Plos Genetics, ISSN 1553-7404, 2013, Volume 9, Issue 3, p. e1003284
Various common genetic susceptibility loci have been identified for breast cancer; however, it is unclear how they combine with lifestyle/environmental risk...
CONSORTIUM | MAMMOGRAPHIC DENSITY | WOMEN | 14Q24.1 RAD51L1 | HORMONE-THERAPY | TUMOR SUBTYPES | VARIANTS | GENETICS & HEREDITY | POOLED ANALYSIS | FGFR2 | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Middle Aged | Risk Factors | European Continental Ancestry Group | Genotype | Gene-Environment Interaction | Caspase 8 - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Alleles | Female | Polymorphism, Single Nucleotide | Microfilament Proteins - genetics | Physiological aspects | Environmental aspects | Breast cancer | Genetic aspects | Disease susceptibility | Research | Risk factors | Cancer | Medicine | Confidence intervals | Medical research | Body mass index | Hospitals | Biomedical research | Councils | Womens health | Genes | Colleges & universities | Endocrine therapy
CONSORTIUM | MAMMOGRAPHIC DENSITY | WOMEN | 14Q24.1 RAD51L1 | HORMONE-THERAPY | TUMOR SUBTYPES | VARIANTS | GENETICS & HEREDITY | POOLED ANALYSIS | FGFR2 | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Middle Aged | Risk Factors | European Continental Ancestry Group | Genotype | Gene-Environment Interaction | Caspase 8 - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Alleles | Female | Polymorphism, Single Nucleotide | Microfilament Proteins - genetics | Physiological aspects | Environmental aspects | Breast cancer | Genetic aspects | Disease susceptibility | Research | Risk factors | Cancer | Medicine | Confidence intervals | Medical research | Body mass index | Hospitals | Biomedical research | Councils | Womens health | Genes | Colleges & universities | Endocrine therapy
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 9/2008, Volume 168, Issue 6, pp. 620 - 631
The study aim was to determine the risk of cataract among radiologic technologists with respect to occupational and nonoccupational exposures to ionizing...
Cataract | Technology, radiologic | Radiation | X-rays | SURGERY | POPULATION | cataract | ATOMIC-BOMB SURVIVORS | LENS OPACITIES | x-rays | technology | GAMMA-RADIATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | radiation | radiologic | EPIDEMIOLOGIC ASSOCIATIONS | BODY-MASS INDEX | LENTICULAR OPACITIES | HEALTH | EYE CARE | Smoking - adverse effects | United States - epidemiology | Confidence Intervals | Follow-Up Studies | Cataract - etiology | Occupational Exposure - adverse effects | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Adult | Female | Surveys and Questionnaires | Dose-Response Relationship, Radiation | Cohort Studies | Radiation, Ionizing | Occupational health and safety | Ionizing radiation | Radiologists | Research | Health aspects | Risk factors | Cataracts | Radiation therapy | Epidemiology | Clinical outcomes | Index Medicus | technology, radiologic | Original Contributions
Cataract | Technology, radiologic | Radiation | X-rays | SURGERY | POPULATION | cataract | ATOMIC-BOMB SURVIVORS | LENS OPACITIES | x-rays | technology | GAMMA-RADIATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | radiation | radiologic | EPIDEMIOLOGIC ASSOCIATIONS | BODY-MASS INDEX | LENTICULAR OPACITIES | HEALTH | EYE CARE | Smoking - adverse effects | United States - epidemiology | Confidence Intervals | Follow-Up Studies | Cataract - etiology | Occupational Exposure - adverse effects | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Adult | Female | Surveys and Questionnaires | Dose-Response Relationship, Radiation | Cohort Studies | Radiation, Ionizing | Occupational health and safety | Ionizing radiation | Radiologists | Research | Health aspects | Risk factors | Cataracts | Radiation therapy | Epidemiology | Clinical outcomes | Index Medicus | technology, radiologic | Original Contributions
Journal Article
Radiation Research, ISSN 0033-7587, 2010, Volume 174, Issue 6, pp. 741 - 752
Abstract Previous studies have indicated that thyroid cancer risk after a first childhood malignancy is curvilinear with radiation dose, increasing at low to...
Radiation dose response relationship | Dose response relationship | Chemotherapy | Thyroid cancer | Leukemia | Childhood | Radiotherapy | Parametric models | Radiation dosage | Age | CERVIX | BIOPHYSICS | UKRAINE | DISEASE | BIOLOGY | ACCIDENT | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CHEMOTHERAPY | EXPOSURE | Age Factors | Humans | Neoplasms, Radiation-Induced - etiology | Thyroid Neoplasms - etiology | Survivors | Male | Risk | Neoplasms, Second Primary - etiology | Female | Neoplasms - radiotherapy | Child | Dose-Response Relationship, Radiation | Cohort Studies
Radiation dose response relationship | Dose response relationship | Chemotherapy | Thyroid cancer | Leukemia | Childhood | Radiotherapy | Parametric models | Radiation dosage | Age | CERVIX | BIOPHYSICS | UKRAINE | DISEASE | BIOLOGY | ACCIDENT | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CHEMOTHERAPY | EXPOSURE | Age Factors | Humans | Neoplasms, Radiation-Induced - etiology | Thyroid Neoplasms - etiology | Survivors | Male | Risk | Neoplasms, Second Primary - etiology | Female | Neoplasms - radiotherapy | Child | Dose-Response Relationship, Radiation | Cohort Studies
Journal Article
The Lancet, ISSN 0140-6736, 2005, Volume 365, Issue 9476, pp. 2014 - 2023
Survivors of malignant disease in childhood who have had radiotherapy to the head, neck, or upper thorax have an increased risk of subsequent primary thyroid...
IRRADIATION | MEDICINE, GENERAL & INTERNAL | HODGKINS-DISEASE | BONE-MARROW-TRANSPLANTATION | EPIDEMIOLOGIC EVIDENCE | RISK | THERAPEUTIC RADIATION | NEUROBLASTOMA | RADIOTHERAPY | ADOLESCENCE | 2ND MALIGNANT NEOPLASMS | Radiotherapy Dosage | Thyroid Gland - radiation effects | Humans | Thyroid Neoplasms - etiology | Male | Case-Control Studies | Neoplasms, Second Primary - etiology | Adolescent | Adult | Female | Child | Dose-Response Relationship, Radiation | Neoplasms, Radiation-Induced | Case studies | Thyroid cancer | Children | Health aspects | Thyroid gland | Health risk assessment | Cancer | Children & youth
IRRADIATION | MEDICINE, GENERAL & INTERNAL | HODGKINS-DISEASE | BONE-MARROW-TRANSPLANTATION | EPIDEMIOLOGIC EVIDENCE | RISK | THERAPEUTIC RADIATION | NEUROBLASTOMA | RADIOTHERAPY | ADOLESCENCE | 2ND MALIGNANT NEOPLASMS | Radiotherapy Dosage | Thyroid Gland - radiation effects | Humans | Thyroid Neoplasms - etiology | Male | Case-Control Studies | Neoplasms, Second Primary - etiology | Adolescent | Adult | Female | Child | Dose-Response Relationship, Radiation | Neoplasms, Radiation-Induced | Case studies | Thyroid cancer | Children | Health aspects | Thyroid gland | Health risk assessment | Cancer | Children & youth
Journal Article
Radiation Research, ISSN 0033-7587, 2014, Volume 182, Issue 5, pp. 507 - 528
In this article, we describe recent methodological enhancements and findings from the dose reconstruction component of a study of health risks among U.S....
UNITED-STATES | REGRESSION | CALIBRATION | WORKERS | CANCER INCIDENCE | RISK | DIAGNOSTIC-RADIOLOGY | LUNG-CANCER | PERSONNEL | BIOPHYSICS | BIOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | EXPOSURE | Uncertainty | Occupational Exposure - analysis | Time Factors | United States | Humans | Technology, Radiologic | Female | Male | Radiation Dosage | Cohort Studies
UNITED-STATES | REGRESSION | CALIBRATION | WORKERS | CANCER INCIDENCE | RISK | DIAGNOSTIC-RADIOLOGY | LUNG-CANCER | PERSONNEL | BIOPHYSICS | BIOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | EXPOSURE | Uncertainty | Occupational Exposure - analysis | Time Factors | United States | Humans | Technology, Radiologic | Female | Male | Radiation Dosage | Cohort Studies
Journal Article
International Journal of Cancer, ISSN 0020-7136, 11/2018, Volume 143, Issue 9, pp. 2145 - 2149
Although childhood exposure to ionizing radiation is a well‐established risk factor for thyroid cancer, the risk associated with adulthood exposure remains...
thyroid cancer | cohort study | radiologic technologists | occupational exposure | ionizing radiation | ONCOLOGY | WORKERS | RISK | HEALTH | REGISTRY | Care and treatment | Ionizing radiation | Thyroid cancer | Oncology, Experimental | Research | Risk factors | Cancer | Radiation effects | Statistical analysis | Health risks | Thyroid gland | Exposure | Risk analysis | Occupational exposure | Radiation dosage | Incidence | Body mass index | Body mass | Body size | Poisson density functions | Technologists | Children | Health risk assessment | Thyroid
thyroid cancer | cohort study | radiologic technologists | occupational exposure | ionizing radiation | ONCOLOGY | WORKERS | RISK | HEALTH | REGISTRY | Care and treatment | Ionizing radiation | Thyroid cancer | Oncology, Experimental | Research | Risk factors | Cancer | Radiation effects | Statistical analysis | Health risks | Thyroid gland | Exposure | Risk analysis | Occupational exposure | Radiation dosage | Incidence | Body mass index | Body mass | Body size | Poisson density functions | Technologists | Children | Health risk assessment | Thyroid
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e39103
The strong and consistent relationship between irradiation at a young age and subsequent thyroid cancer provides an excellent model for studying radiation...
EPIGENETIC MECHANISMS | GAMMA-IRRADIATION | CELLS | IN-VITRO | UKRAINE | POST-CHERNOBYL | MULTIDISCIPLINARY SCIENCES | IONIZING-RADIATION | REARRANGEMENTS | PAPILLARY CARCINOMAS | EXPOSURE | Humans | Middle Aged | Chernobyl Nuclear Accident | Gene Expression Regulation, Neoplastic | Real-Time Polymerase Chain Reaction - methods | Male | Neoplasms, Radiation-Induced - metabolism | Iodine Radioisotopes - metabolism | RNA, Neoplasm - biosynthesis | Adult | Female | Neoplasms, Radiation-Induced - pathology | Dose-Response Relationship, Radiation | Cohort Studies | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Thyroid cancer | RNA | Analysis | Genomics | Genes | Quality control | Radiation | Genetic aspects | Gene expression | Cancer | Laboratories | Genomes | Hybridization | Tissues | Epidemiology | Carcinogenesis | Stomach cancer | Carcinogens | Regression models | Gangrene | Genetics | Nuclear power plants | Dosimetry | Deoxyribonucleic acid--DNA | Iodine | Thyroid | Statistical analysis | Iodine 131 | Radioactive fallout | Data processing | Regression analysis | Metabolism | Ribonucleic acid--RNA | Radiation dosage | Studies | Pathology | DNA microarrays | Epigenetics | Irradiation | Lymphomas | Endocrinology | Apoptosis | Deoxyribonucleic acid | Ribonucleic acid | DNA
EPIGENETIC MECHANISMS | GAMMA-IRRADIATION | CELLS | IN-VITRO | UKRAINE | POST-CHERNOBYL | MULTIDISCIPLINARY SCIENCES | IONIZING-RADIATION | REARRANGEMENTS | PAPILLARY CARCINOMAS | EXPOSURE | Humans | Middle Aged | Chernobyl Nuclear Accident | Gene Expression Regulation, Neoplastic | Real-Time Polymerase Chain Reaction - methods | Male | Neoplasms, Radiation-Induced - metabolism | Iodine Radioisotopes - metabolism | RNA, Neoplasm - biosynthesis | Adult | Female | Neoplasms, Radiation-Induced - pathology | Dose-Response Relationship, Radiation | Cohort Studies | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Thyroid cancer | RNA | Analysis | Genomics | Genes | Quality control | Radiation | Genetic aspects | Gene expression | Cancer | Laboratories | Genomes | Hybridization | Tissues | Epidemiology | Carcinogenesis | Stomach cancer | Carcinogens | Regression models | Gangrene | Genetics | Nuclear power plants | Dosimetry | Deoxyribonucleic acid--DNA | Iodine | Thyroid | Statistical analysis | Iodine 131 | Radioactive fallout | Data processing | Regression analysis | Metabolism | Ribonucleic acid--RNA | Radiation dosage | Studies | Pathology | DNA microarrays | Epigenetics | Irradiation | Lymphomas | Endocrinology | Apoptosis | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
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Full Text
Melanoma, thyroid cancer, and gynecologic cancers in a cohort of female flight attendants
American Journal of Industrial Medicine, ISSN 0271-3586, 07/2018, Volume 61, Issue 7, pp. 572 - 581
Background Flight attendants may have an increased risk of some cancers from occupational exposure to cosmic radiation and circadian disruption. Methods The...
circadian rhythm disruption | cohort studies | cancer | exposure response | cosmic ionizing radiation | flight attendants | COSMIC-RADIATION EXPOSURE | OVARIAN-CANCER | CHERNOBYL ACCIDENT | OCCUPATIONAL COHORT | BREAST-CANCER | CABIN CREW | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | AIRLINE PILOTS | NIGHT-SHIFT WORK | NURSES HEALTH | SKIN-CANCER | Occupational health and safety | Thyroid cancer | Analysis | Melanoma | Radiation | Flight attendants | Risk factors | Cervical cancer | Circadian rhythms | Flight | Health risks | Exposure | Regression analysis | Cervix | Risk analysis | Occupational exposure | Cosmic radiation | Cosmic rays | Radiation dosage | Incidence | Occupational health | Uterine cancer | Cancer | Thyroid
circadian rhythm disruption | cohort studies | cancer | exposure response | cosmic ionizing radiation | flight attendants | COSMIC-RADIATION EXPOSURE | OVARIAN-CANCER | CHERNOBYL ACCIDENT | OCCUPATIONAL COHORT | BREAST-CANCER | CABIN CREW | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | AIRLINE PILOTS | NIGHT-SHIFT WORK | NURSES HEALTH | SKIN-CANCER | Occupational health and safety | Thyroid cancer | Analysis | Melanoma | Radiation | Flight attendants | Risk factors | Cervical cancer | Circadian rhythms | Flight | Health risks | Exposure | Regression analysis | Cervix | Risk analysis | Occupational exposure | Cosmic radiation | Cosmic rays | Radiation dosage | Incidence | Occupational health | Uterine cancer | Cancer | Thyroid
Journal Article
Occupational and Environmental Medicine, ISSN 1351-0711, 01/2016, Volume 73, Issue 1, pp. 21 - 27
ObjectivesAlthough fluoroscopically guided interventional procedures (FGIP) have provided major advances in the treatment of various common diseases, radiation...
STROKE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | RADIATION RISKS | EXPOSURE | Radiology - methods | United States - epidemiology | Prospective Studies | Humans | Middle Aged | Occupational Diseases - etiology | Occupations | Male | Incidence | Allied Health Personnel | Occupational Diseases - mortality | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Radiation Exposure - adverse effects | Adult | Female | Stroke - epidemiology | Stroke - mortality | Cardiovascular Diseases - etiology | Occupational Exposure - adverse effects | Risk Factors | Proportional Hazards Models | Fluoroscopy | X-Rays - adverse effects | Stroke - etiology | Technology, Radiologic | Occupational Diseases - epidemiology | Stroke (Disease) | United States | Mortality | Analysis | Risk factors | Studies | Heart attacks | Health risk assessment | Radiation effects | Risk | Strokes | Technologists | Heart diseases | Diseases
STROKE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | RADIATION RISKS | EXPOSURE | Radiology - methods | United States - epidemiology | Prospective Studies | Humans | Middle Aged | Occupational Diseases - etiology | Occupations | Male | Incidence | Allied Health Personnel | Occupational Diseases - mortality | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Radiation Exposure - adverse effects | Adult | Female | Stroke - epidemiology | Stroke - mortality | Cardiovascular Diseases - etiology | Occupational Exposure - adverse effects | Risk Factors | Proportional Hazards Models | Fluoroscopy | X-Rays - adverse effects | Stroke - etiology | Technology, Radiologic | Occupational Diseases - epidemiology | Stroke (Disease) | United States | Mortality | Analysis | Risk factors | Studies | Heart attacks | Health risk assessment | Radiation effects | Risk | Strokes | Technologists | Heart diseases | Diseases
Journal Article
Radiation Research, ISSN 0033-7587, 2014, Volume 182, Issue 1, pp. 1 - 17
Chromosome translocations are a well-recognized biological marker of radiation exposure and cancer risk. However, there is uncertainty about the lowest dose at...
X-RAY EXAMINATIONS | WORKERS | PERIPHERAL-BLOOD | BIOPHYSICS | MEASUREMENT ERROR | BIOLOGY | CANCER-RISK | FISH | UNCERTAINTY | IONIZING-RADIATION | ABERRATIONS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | INCREASED FREQUENCY | Translocation, Genetic - radiation effects | Occupational Exposure - adverse effects | Humans | Middle Aged | Probability | In Situ Hybridization, Fluorescence | Male | Risk | Time Factors | Aged, 80 and over | Female | Aged | Technology, Radiologic - statistics & numerical data | Dose-Response Relationship, Radiation | Monte Carlo Method | Occupational Exposure - statistics & numerical data | Cohort Studies
X-RAY EXAMINATIONS | WORKERS | PERIPHERAL-BLOOD | BIOPHYSICS | MEASUREMENT ERROR | BIOLOGY | CANCER-RISK | FISH | UNCERTAINTY | IONIZING-RADIATION | ABERRATIONS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | INCREASED FREQUENCY | Translocation, Genetic - radiation effects | Occupational Exposure - adverse effects | Humans | Middle Aged | Probability | In Situ Hybridization, Fluorescence | Male | Risk | Time Factors | Aged, 80 and over | Female | Aged | Technology, Radiologic - statistics & numerical data | Dose-Response Relationship, Radiation | Monte Carlo Method | Occupational Exposure - statistics & numerical data | Cohort Studies
Journal Article
Scandinavian Journal of Work, Environment & Health, ISSN 0355-3140, 11/2016, Volume 42, Issue 6, pp. 538 - 546
Objective The aim of this study was to examine the association of breast cancer incidence with cosmic radiation dose and circadian rhythm disruption in a...
cohort study | CIRCADIAN-RHYTHM DISRUPTION | METAANALYSIS | RISK | cosmic ionizing radiation | BOMB SURVIVORS | circadian rhythm disruption | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | AIRLINE CABIN ATTENDANTS | COSMIC-RADIATION | airline attendant | COHORT | ICELAND | CREW | United States - epidemiology | Aircraft - history | Occupational Exposure - adverse effects | History, 20th Century | Humans | Risk Factors | Incidence | Occupational Health - statistics & numerical data | Cosmic Radiation - adverse effects | Female | Interviews as Topic | Surveys and Questionnaires | Retrospective Studies | Circadian Rhythm - radiation effects | Breast Neoplasms - epidemiology
cohort study | CIRCADIAN-RHYTHM DISRUPTION | METAANALYSIS | RISK | cosmic ionizing radiation | BOMB SURVIVORS | circadian rhythm disruption | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | AIRLINE CABIN ATTENDANTS | COSMIC-RADIATION | airline attendant | COHORT | ICELAND | CREW | United States - epidemiology | Aircraft - history | Occupational Exposure - adverse effects | History, 20th Century | Humans | Risk Factors | Incidence | Occupational Health - statistics & numerical data | Cosmic Radiation - adverse effects | Female | Interviews as Topic | Surveys and Questionnaires | Retrospective Studies | Circadian Rhythm - radiation effects | Breast Neoplasms - epidemiology
Journal Article
Radiation Research, ISSN 0033-7587, 2016, Volume 185, Issue 4, pp. 366 - 374
With therapeutic successes and improved survival after a cancer diagnosis in childhood, increasing numbers of cancer survivors are at risk of subsequent...
UNITED-STATES | SURGERY | OCULAR COMPLICATIONS | IRRADIATION | BIOPHYSICS | BONE-MARROW-TRANSPLANTATION | BIOLOGY | COHORT | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | EXPOSURE | Cataract - etiology | Humans | Lens, Crystalline - radiation effects | Middle Aged | Survivors - statistics & numerical data | Male | Cataract - epidemiology | Models, Statistical | Radiation Injuries - etiology | Young Adult | Radiation Injuries - epidemiology | Adolescent | Adult | Female | Neoplasms - radiotherapy | Child | Dose-Response Relationship, Radiation | Physiological aspects | Cataract | Radiotherapy | Patient outcomes | Risk factors | Cancer in children | Cataracts | Ionizing radiation | Regression | Risk | Diagnosis | Logistics | Cancer
UNITED-STATES | SURGERY | OCULAR COMPLICATIONS | IRRADIATION | BIOPHYSICS | BONE-MARROW-TRANSPLANTATION | BIOLOGY | COHORT | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | EXPOSURE | Cataract - etiology | Humans | Lens, Crystalline - radiation effects | Middle Aged | Survivors - statistics & numerical data | Male | Cataract - epidemiology | Models, Statistical | Radiation Injuries - etiology | Young Adult | Radiation Injuries - epidemiology | Adolescent | Adult | Female | Neoplasms - radiotherapy | Child | Dose-Response Relationship, Radiation | Physiological aspects | Cataract | Radiotherapy | Patient outcomes | Risk factors | Cancer in children | Cataracts | Ionizing radiation | Regression | Risk | Diagnosis | Logistics | Cancer
Journal Article