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1. Full Text GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength
by Andrews, Jeffrey C and Schünemann, Holger J and Oxman, Andrew D and Pottie, Kevin and Meerpohl, Joerg J and Coello, Pablo Alonso and Rind, David and Montori, Victor M and Brito, Juan Pablo and Norris, Susan and Elbarbary, Mahmoud and Post, Piet and Nasser, Mona and Shukla, Vijay and Jaeschke, Roman and Brozek, Jan and Djulbegovic, Ben and Guyatt, Gordon
Journal of Clinical Epidemiology, ISSN 0895-4356, 2013, Volume 66, Issue 7, pp. 726 - 735
Abstract In the GRADE approach, the strength of a recommendation reflects the extent to which we can be confident that the composite desirable effects of a... 
Internal Medicine | Strength of evidence | Guideline development | GRADE | Evidence | Quality of evidence | Recommendation | QUALITY | MANAGEMENT | FINDINGS TABLES | SOCIETY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | NONCARDIAC SURGERY | DISEASE | HEALTH CARE SCIENCES & SERVICES | INFECTION | ESTROGEN PLUS PROGESTIN | Risk Assessment | Practice Guidelines as Topic - standards | United States | Humans | Treatment Outcome | Pulmonary Disease, Chronic Obstructive - physiopathology | Quality Assurance, Health Care | Evidence-Based Medicine - standards | Canada | Pulmonary Disease, Chronic Obstructive - rehabilitation | Treatment Failure | Research Design - standards | Pulmonary Disease, Chronic Obstructive - economics | Germany | Intervention | Nuclear magnetic resonance--NMR | Chronic obstructive pulmonary disease | Bone density | Drug therapy | Alternatives | Cancer therapies | Patients | Composite materials
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2. Full Text GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction
by Alonso-Coello, Pablo and Schünemann, Holger J and Moberg, Jenny and Brignardello-Petersen, Romina and Akl, Elie A and Davoli, Marina and Treweek, Shaun and Mustafa, Reem A and Rada, Gabriel and Rosenbaum, Sarah and Morelli, Angela and Guyatt, Gordon H and Oxman, Andrew D and GRADE Working Grp and GRADE Working Group and the GRADE Working Group
BMJ, ISSN 0959-8146, 6/2016, Volume 353, p. i2016
CLINICAL-PRACTICE GUIDELINES | TECHNOLOGY-ASSESSMENT | MULTIPLE CRITERIA | CONFLICT | MEDICINE, GENERAL & INTERNAL | AUSTRALIA | QUALITY | COVERAGE DECISIONS | RECOMMENDATIONS | INTERNATIONAL NETWORK | STANDARDS | Choice Behavior | Evidence-Based Medicine | Delivery of Health Care | Humans | Decision Support Techniques
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3. Full Text GRADE guidelines: 7. Rating the quality of evidence—inconsistency
by Guyatt, Gordon H and Oxman, Andrew D and Kunz, Regina and Woodcock, James and Brozek, Jan and Helfand, Mark and Alonso-Coello, Pablo and Glasziou, Paul and Jaeschke, Roman and Akl, Elie A and Norris, Susan and Vist, Gunn and Dahm, Philipp and Shukla, Vijay K and Higgins, Julian and Falck-Ytter, Yngve and Schünemann, Holger J and GRADE Working Grp and GRADE Working Group
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 12, pp. 1294 - 1302
Abstract This article deals with inconsistency of relative (rather than absolute) treatment effects in binary/dichotomous outcomes. A body of evidence is not... 
Internal Medicine | Heterogeneity | GRADE | Sub-group analysis | Inconsistency | Variability | Interaction | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | METAANALYSIS | CLINICAL-TRIALS | VASOPRESSIN | EPINEPHRINE | Evidence-Based Medicine - standards | Confidence Intervals | Sample Size | Humans | Research Design | Observer Variation | Practice Guidelines as Topic | Randomized Controlled Trials as Topic - standards | Medical colleges | Analysis | Biometry | Medical informatics | Studies | Confidence intervals | Hypotheses | Heart attacks | Bias | Ratings & rankings | Estimates
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4. Full Text GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
by Guyatt, Gordon H and Oxman, Andrew D and Vist, Gunn E and Kunz, Regina and Falck-Ytter, Yngve and Alonso-Coello, Pablo and Schünemann, Holger J and GRADE Working Grp and GRADE Working Group
BMJ, ISSN 0959-8138, 04/2008, Volume 336, Issue 7650, pp. 924 - 926
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE... 
TRIAL | MEDICINE, GENERAL & INTERNAL | THERAPY | DISEASE | PREVENTION | ESTROGEN PLUS PROGESTIN | POSTMENOPAUSAL WOMEN | Decision Making | Evidence-Based Medicine - standards | Practice Guidelines as Topic - standards | Consensus | Quality Indicators, Health Care | Analysis
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5. Full Text GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
by Guyatt, Gordon H and Oxman, Andrew D and Vist, Gunn and Kunz, Regina and Brozek, Jan and Alonso-Coello, Pablo and Montori, Victor and Akl, Elie A and Djulbegovic, Ben and Falck-Ytter, Yngve and Norris, Susan L and Williams, John W and Atkins, David and Meerpohl, Joerg and Schünemann, Holger J
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 4, pp. 407 - 415
Abstract In the GRADE approach, randomized trials start as high-quality evidence and observational studies as low-quality evidence, but both can be rated down... 
Internal Medicine | risk of bias | concealment | GRADE | quality of evidence | confidence in estimates | blinding | RANDOMIZED CONTROLLED-TRIALS | METAANALYSIS | HEART-FAILURE | BENEFIT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | THERAPY | OUTCOME REPORTING BIAS | VENOUS THROMBOEMBOLISM | CLINICAL-TRIALS | EMPIRICAL-EVIDENCE | SPINAL-CORD-INJURY | Evidence-Based Practice | Risk Assessment | Practice Guidelines as Topic - standards | Humans | Publication Bias | Female | Male | Quality Assurance, Health Care - standards | Randomized Controlled Trials as Topic
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6. Full Text GRADE guidelines: 8. Rating the quality of evidence—indirectness
by Guyatt, Gordon H and Oxman, Andrew D and Kunz, Regina and Woodcock, James and Brozek, Jan and Helfand, Mark and Alonso-Coello, Pablo and Falck-Ytter, Yngve and Jaeschke, Roman and Vist, Gunn and Akl, Elie A and Post, Piet N and Norris, Susan and Meerpohl, Joerg and Shukla, Vijay K and Nasser, Mona and Schünemann, Holger J and GRADE Working Group
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 12, pp. 1303 - 1310
Abstract Direct evidence comes from research that directly compares the interventions in which we are interested when applied to the populations in which we... 
Internal Medicine | GRADE | Applicability | Generalizability | Quality of evidence | Indirectness | Indirect comparisons | RANDOMIZED CONTROLLED-TRIALS | INTERVENTIONS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | METAANALYSIS | THERAPY | CANCER | Evidence-Based Medicine - standards | Clinical Competence | Meta-Analysis as Topic | Review Literature as Topic | Bias | Humans | Practice Guidelines as Topic | Randomized Controlled Trials as Topic - standards | Analysis | Biometry | Collateralized debt obligations | Quality management | Medical informatics
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7. Full Text GRADE guidelines: 5. Rating the quality of evidence—publication bias
by Guyatt, Gordon H and Oxman, Andrew D and Montori, Victor and Vist, Gunn and Kunz, Regina and Brozek, Jan and Alonso-Coello, Pablo and Djulbegovic, Ben and Atkins, David and Falck-Ytter, Yngve and Williams, John W and Meerpohl, Joerg and Norris, Susan L and Akl, Elie A and Schünemann, Holger J
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 12, pp. 1277 - 1282
Abstract In the GRADE approach, randomized trials start as high-quality evidence and observational studies as low-quality evidence, but both can be rated down... 
Internal Medicine | Funnel plot | GRADE | Publication bias | Pharmaceutical industry | Quality of evidence | Conflict of interest | DRUG | SYSTEMATIC REVIEWS | METAANALYSIS | GRAPHICAL TEST | DUPLICATE PUBLICATION | ESTIMATING EFFECT SIZE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EMPIRICAL-EVALUATION | HEALTH CARE SCIENCES & SERVICES | CLINICAL-TRIAL REGISTRATION | PHARMACEUTICAL-INDUSTRY | Evidence-Based Medicine - standards | Meta-Analysis as Topic | Cross-Sectional Studies | Review Literature as Topic | Drug Industry | Publication Bias | Statistics as Topic | Practice Guidelines as Topic | Randomized Controlled Trials as Topic - standards | Research | Oncology, Experimental | Biometry | Cancer | Medical informatics
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8. Full Text GRADE guidelines: 12. Preparing Summary of Findings tables—binary outcomes
by Guyatt, Gordon H and Oxman, Andrew D and Santesso, Nancy and Helfand, Mark and Vist, Gunn and Kunz, Regina and Brozek, Jan and Norris, Susan and Meerpohl, Joerg and Djulbegovic, Ben and Alonso-Coello, Pablo and Post, Piet N and Busse, Jason W and Glasziou, Paul and Christensen, Robin and Schünemann, Holger J
Journal of Clinical Epidemiology, ISSN 0895-4356, 2013, Volume 66, Issue 2, pp. 158 - 172
Abstract Summary of Findings (SoF) tables present, for each of the seven (or fewer) most important outcomes, the following: the number of studies and number of... 
Internal Medicine | Systematic reviews | GRADE | Summary of findings | Confidence in estimates | Quality of evidence | Evidence profile | OCTREOTIDE | QUALITY | METAANALYSIS | COCHRANE REVIEWS | NATURAL FREQUENCIES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | DIFFERENCE | SULFONYLUREA-INDUCED HYPOGLYCEMIA | CLINICAL-TRIALS | Decision Making | Quality Assurance, Health Care - organization & administration | Confidence Intervals | Guideline Adherence - standards | Practice Guidelines as Topic - standards | Humans | Models, Organizational | Treatment Outcome | Guideline Adherence - organization & administration | Randomized Controlled Trials as Topic | Evidence-Based Medicine - standards | Evidence-Based Medicine - organization & administration | Quality Improvement | Ontario | Quality Assurance, Health Care - standards | Research Design | Oncology, Experimental | Collateralized debt obligations | Research | Universities and colleges | Biometry | Public health | Cancer | Medical informatics | Studies | Confidence intervals | Compression therapy | Older people | Mortality | Clinical trials | Chronic obstructive pulmonary disease | Drug therapy | Hypoglycemia | Thrombosis | Estimates | Quality of life
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9. Full Text GRADE guidelines: 9. Rating up the quality of evidence
by Guyatt, Gordon H and Oxman, Andrew D and Sultan, Shahnaz and Glasziou, Paul and Akl, Elie A and Alonso-Coello, Pablo and Atkins, David and Kunz, Regina and Brozek, Jan and Montori, Victor and Jaeschke, Roman and Rind, David and Dahm, Philipp and Meerpohl, Joerg and Vist, Gunn and Berliner, Elise and Norris, Susan and Falck-Ytter, Yngve and Murad, M. Hassan and Schünemann, Holger J and GRADE Working Grp and GRADE Working Group
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 12, pp. 1311 - 1316
Abstract The most common reason for rating up the quality of evidence is a large effect. GRADE suggests considering rating up quality of evidence one level... 
Internal Medicine | GRADE | Large effects | Level of evidence | Risk of bias | Observational studies | Guidelines | MORTALITY | VASOVAGAL PACEMAKER | MULTICENTER | SEROCONVERSION | SYNCOPE | VACCINE | PREVENTION | RISK | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | THERAPY | DISEASE | HEALTH CARE SCIENCES & SERVICES | Evidence-Based Medicine - standards | Risk | Evidence-Based Medicine - statistics & numerical data | Practice Guidelines as Topic - standards | Humans | Observer Variation | Medical care | Medical colleges | Analysis | Biometry | Medical informatics | Quality management
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10. Full Text GRADE guidelines 6. Rating the quality of evidence—imprecision
by Guyatt, Gordon H and Oxman, Andrew D and Kunz, Regina and Brozek, Jan and Alonso-Coello, Pablo and Rind, David and Devereaux, P.J and Montori, Victor M and Freyschuss, Bo and Vist, Gunn and Jaeschke, Roman and Williams, John W and Murad, Mohammad Hassan and Sinclair, David and Falck-Ytter, Yngve and Meerpohl, Joerg and Whittington, Craig and Thorlund, Kristian and Andrews, Jeff and Schünemann, Holger J
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 12, pp. 1283 - 1293
Abstract GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal primary approach to decisions regarding imprecision. For... 
Internal Medicine | Confidence intervals | GRADE | Optimal information size | Confidence in estimates | Quality of evidence | Imprecision | MORTALITY | RANDOMIZED CONTROLLED-TRIALS | METAANALYSIS | PREVENTION | ASPIRIN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PERIOPERATIVE BETA-BLOCKERS | NONCARDIAC SURGERY | INTRAVENOUS MAGNESIUM | ACUTE MYOCARDIAL-INFARCTION | ALBUMIN | Evidence-Based Medicine - standards | Confidence Intervals | Meta-Analysis as Topic | Sample Size | Humans | Risk | Practice Guidelines as Topic | Randomized Controlled Trials as Topic - standards | Medical colleges | Evaluation | Health aspects | Biometry | Psychiatric services | Quality management | Medical informatics | Studies | Drug therapy | Ratings & rankings | Bias
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