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Monthly Notices of the Royal Astronomical Society, ISSN 0035-8711, 09/2018, Volume 479, Issue 3, pp. 3197 - 3205
AR CrB (GSC 2040-1361) is a W UMa-type binary system (P = 0.397351 d) which has been poorly studied since first detected over 17 yr ago; only a single... 
Techniques: photometric | Techniques: radial velocities | Starspots | Binaries: eclipsing | binaries: eclipsing | CONTACT | EVOLUTION | techniques: radial velocities | techniques: photometric | ASTRONOMY & ASTROPHYSICS | VARIABLE-STARS | LIGHT CURVES | starspots | URSAE-MAJORIS BINARIES
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2011, Volume 255, Issue 1, pp. 48 - 56
An investigative renal toxicity study using metabolomics was conducted with a potent nicotinic acid receptor (NAR) agonist, SCH 900424. Liquid... 
3-indoxyl sulfate | Metabolomics | Mice | Nicotinic acid agonist | Acute kidney injury | Central nervous system | ORGANIC ANION TRANSPORTER | UREMIC TOXINS | BIOMARKER | RENAL METABOLISM | INVOLVEMENT | FAILURE | INDOXYL SULFATE | AMINO-ACIDS | TUBULAR INJURY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | NEPHROTOXICITY | Kidney - drug effects | Indican - analysis | Male | Indican - blood | Brain - metabolism | Organic Anion Transport Protein 1 - physiology | Animals | Biomarkers | Acute Kidney Injury - chemically induced | Acute Kidney Injury - metabolism | Nicotinic Agonists - toxicity | Organic Anion Transporters, Sodium-Independent - physiology | Urea | Methylcellulose | Analysis | Tryptophan | Sulfates | Niacin | Investigations | Index Medicus | AZOLES | BODY FLUIDS | NICOTINIC ACID | NERVOUS SYSTEM | HETEROCYCLIC COMPOUNDS | PYRIDINES | CHROMATOGRAPHY | 60 APPLIED LIFE SCIENCES | PLASMA | LIQUID COLUMN CHROMATOGRAPHY | AMINO ACIDS | KETO ACIDS | VERTEBRATES | VITAMINS | ORGANIC NITROGEN COMPOUNDS | BRAIN | BLOOD | MEMBRANE PROTEINS | BIOLOGICAL MATERIALS | ORGANIC ACIDS | TOXICITY | CENTRAL NERVOUS SYSTEM | PYRROLES | INDOLES | CARBOXYLIC ACIDS | MONOCARBOXYLIC ACIDS | GAS CHROMATOGRAPHY | RECEPTORS | BODY | MATERIALS | ANIONS | OXYGEN COMPOUNDS | IMINES | SULFUR COMPOUNDS | RATS | IONS | MASS SPECTROSCOPY | AZINES | KIDNEYS | CARBONIC ACID DERIVATIVES | BIOLOGICAL MARKERS | CHARGED PARTICLES | DRUGS | SEPARATION PROCESSES | MICE | AROMATICS | UREA | MAMMALS | KYNURENINE | TRYPTOPHAN | ANIMALS | HETEROCYCLIC ACIDS | SULFATES | RODENTS | ORGANIC COMPOUNDS | IMIDAZOLES | ORGANS | SPECTROSCOPY | CREATININE | PROTEINS | AZAARENES | VITAMIN B GROUP | AMIDES
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 03/2011, Volume 39, Issue 3, pp. 510 - 521
Boceprevir (SCH 503034), a protease inhibitor, is under clinical development for the treatment of human hepatitis C virus infections. In human liver... 
METABOLISM | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NS3 PROTEASE | ALDO-KETO REDUCTASES | CARBONYL REDUCTION | NEUROSTEROIDS | SUPERFAMILY | PHARMACOLOGY & PHARMACY | AGENTS | DEHYDROGENASE | HIV-INTEGRASE INHIBITOR | Liver - enzymology | Proline - metabolism | Stereoisomerism | Humans | Drugs, Investigational - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Urea - chemistry | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Drugs, Investigational - chemistry | Serine Proteinase Inhibitors - chemistry | Cytochrome P-450 CYP3A - genetics | Urea - analogs & derivatives | 3-Hydroxysteroid Dehydrogenases - metabolism | Hydroxysteroid Dehydrogenases - metabolism | Urea - metabolism | Molecular Structure | Oligopeptides - chemistry | Recombinant Proteins - metabolism | Oxidation-Reduction | Proline - analogs & derivatives | Subcellular Fractions - drug effects | Enzyme Inhibitors - pharmacology | Serine Proteinase Inhibitors - metabolism | Hydroxysteroid Dehydrogenases - genetics | Oligopeptides - metabolism | Subcellular Fractions - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Proline - chemistry | Hepacivirus - enzymology | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Cytochrome P-450 CYP3A Inhibitors | Aldo-Keto Reductase Family 1 Member C3 | Cytochrome P-450 CYP3A - metabolism | Biotransformation - drug effects | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Viral Nonstructural Proteins - antagonists & inhibitors | Subcellular Fractions - enzymology | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Drug Metabolism Letters, ISSN 1872-3128, 08/2009, Volume 3, Issue 3, pp. 162 - 170
Journal Article
Rapid Communications in Mass Spectrometry, ISSN 0951-4198, 2001, Volume 15, Issue 22, pp. 2085 - 2090
The diagnostic fragmentation of N-oxides resulting from loss of the oxygen atom (MH+ --> MH+-O) in electrospray and atmospheric pressure chemical ionization... 
SPECTROSCOPY | CHEMISTRY, ANALYTICAL | Cyclic N-Oxides - chemistry | Pharmaceutical Preparations - metabolism | Temperature | Animals | Spectrometry, Mass, Electrospray Ionization | Hydroxylation | Cyclic N-Oxides - urine | Urine - chemistry | Chromatography, Liquid | Rats | Atmospheric Pressure | Cyclic N-Oxides - pharmacokinetics | Index Medicus
Journal Article
2005, ISBN 9780444517104, Volume 6, Issue C
This chapter introduces a book that deals with the role of modem liquid chromatography-mass spectrometer (LC-MS) in Drug Metabolism. Clearly, advances in mass... 
Book Chapter
Biopharmaceutics & Drug Disposition, ISSN 0142-2782, 09/2004, Volume 25, Issue 6, pp. 243 - 252
Desloratadine is a non‐sedating antihistamine recently approved for the treatment of seasonal allergic rhinitis. The major metabolite of desloratadine in human... 
UGT1A3 | UGT | UGT1A1 | glucuronides | desloratadine | UGT2B15 | Glucuronides | Desloratadine | 1A1 | RAT | HUMAN LIVER-MICROSOMES | LOCUS | IN-VITRO GLUCURONIDATION | PHARMACOLOGY & PHARMACY | EXPRESSION | Diclofenac - pharmacology | Glucuronosyltransferase - administration & dosage | Humans | Microsomes, Liver - metabolism