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Tetrahedron, ISSN 0040-4020, 08/2019, Volume 75, Issue 32, pp. 4255 - 4260
Substrates were designed to undergo tandem radical cyclizations to afford the , -fused hexahydrobenzofurobenzopyran ring system of the bisabosquals. Studies... 
cis fused ring system | Tandem | Cyclization | Radical | Photoredox | Cascade | KETONES | ALKYL | CHEMISTRY, ORGANIC
Journal Article
Chemical Science, ISSN 2041-6520, 2019, Volume 10, Issue 11, pp. 3237 - 3241
Herein, we report the radiosynthesis of F-difluoromethylarenes the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and... 
Journal Article
The Journal of organic chemistry, ISSN 0022-3263, 04/2019, Volume 84, Issue 8, pp. 4904 - 4909
Herein we describe the 2,2,2-trifluoroethoxy group as an alternative leaving group for hydrolytically unstable heteroaryl chlorides. This group provides... 
CHEMISTRY, ORGANIC
Journal Article
Chemical Science, ISSN 2041-6520, 02/2018, Volume 9, Issue 7, pp. 1953 - 1963
A photochemical synthesis of AgNO3 complexes of trans-cycloheptene (TCH) and trans-1-sila-4-cycloheptene (Si-TCH) derivatives is described. A low temperature... 
ALKENES | CYCLOADDITION | CIS-CYCLOOCTENE | CLICK CHEMISTRY | DIELS-ALDER REACTION | COPPER(I) TRIFLATE | REACTIVITY | RELEASE | TETRAZINE LIGATION | CHEMISTRY, MULTIDISCIPLINARY | LIVING CELLS | Labelling | Cycloaddition | Derivatives | Chemical synthesis | Crystallography | Reagents
Journal Article
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 11, pp. 3237 - 3241
Herein, we report the radiosynthesis of 18F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and... 
Boron | Cross coupling | Aromatic compounds | Reagents | Chemical reactions | Fluorides | Cyclotrons
Journal Article
The Journal of organic chemistry, ISSN 0022-3263, 01/2019, Volume 84, Issue 8, pp. 4921 - 4925
An efficient synthesis of pyridopyrazine-1,6-dione -secretase modulators (GSMs) is described. Our route features the construction of a crystalline lactone... 
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 12/2017, Volume 82, Issue 23, pp. 12791 - 12797
We present an operationally simple lactone-to-lactam transformation utilizing diverse amine nucleophiles. The key steps of amidation, alcohol activation, and... 
CHEMISTRY, ORGANIC | GAMMA-SECRETASE MODULATORS | DERIVATIVES | DISCOVERY | ESTERS | LACTAMIZATION | Chemical properties | Chemical synthesis | Analysis | Pyridazine | Lactones
Journal Article
Journal Article
ISSN 2041-6520, 3/2019, Volume 1, Issue 11, pp. 3237 - 3241
Herein, we report the radiosynthesis of 18 F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and... 
Journal Article
Chemical Science, ISSN 2041-6520, 03/2019, Volume 10, Issue 11, pp. 3237 - 3241
Journal Article
Organic Letters, ISSN 1523-7060, 02/2018, Volume 20, Issue 3, pp. 812 - 815
The design, synthesis, and application of [4-(acetylamino)phenyl]imidodisulfuryl difluoride (AISF), a shelf-stable, crystalline reagent for the synthesis of... 
PALLADIUM | POLYSULFATES | ARYL FLUOROSULFONATES | COUPLING REACTIONS | ACIDS | PHENOLS | CHEMISTRY | CHEMISTRY, ORGANIC | SUFEX
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2019, Volume 141, Issue 28, pp. 10932 - 10937
Sulfenylation (RSH ->RSOH) is a post-translational protein modification associated with cellular mech-anisms for signal transduction as well as the regula-tion... 
SPECIFICITY | SULFENIC ACID | CANCER | CHEMISTRY, MULTIDISCIPLINARY | DIMEDONE | BIOLOGY
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2019, Volume 75, Issue 32, pp. 4307 - 4317
Conformationally strained cyclooctenes (TCOs) engage in bioorthogonal reactions with tetrazines with second order rate constants that can exceed 10  M s . The... 
Silver complexation | Radical inhibitor | Stability | Bioorthogonal chemistry | Trans-cyclooctene | Cellular labeling | ACIDS | REACTIVITY | CHEMISTRY, ORGANIC | LIVE CELLS | CYCLOPROPENES | BIOORTHOGONAL REACTIONS | CHEMISTRY | DIENOPHILE | PROBE | TAGS | Silver | Thermodynamics | Thiols | Chemical tests and reagents | Isomerization
Journal Article
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