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1. Full Text Development of a Performance Prediction Program for EVs Powered by Lithium-ion Batteries
by Amada, Naoki, author
SAE technical paper series, Volume 970239.
The performance capabilities which hold the key to the acceptance of electric vehicles (EVs) includes range and acceleration. Range can be effectively extended... 
Lithium-ion batteries | Lithium | Vehicle performance | Energy storage systems | Electric motors
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2. Full Text Global Trends in Alzheimer Disease Clinical Development: Increasing the Probability of Success
by Sugino, Haruhiko, PhD and Watanabe, Akihito, PhD and Amada, Naoki, PhD and Yamamoto, Miho and Ohgi, Yuta, PhD and Kostic, Dusan, PhD and Sanchez, Raymond, MD
Clinical Therapeutics, ISSN 0149-2918, 2015, Volume 37, Issue 8, pp. 1632 - 1642
Abstract Purpose Alzheimer disease (AD) is a growing global health and economic issue as elderly populations increase dramatically across the world. Despite... 
Internal Medicine | Medical Education | drug development | mild cognitive impairment (MCI) | Alzheimer disease (AD) | biomarker | early stage | Key words Alzheimer disease (AD) | CRITERIA | TRIALS | DEMENTIA | SAFETY | DRUG-DEVELOPMENT | MILD COGNITIVE IMPAIRMENT | NATIONAL INSTITUTE | RECOMMENDATIONS | DIAGNOSTIC GUIDELINES | PHARMACOLOGY & PHARMACY | ASSOCIATION WORKGROUPS | Neuroprotective Agents - therapeutic use | Global Health | Alzheimer Disease - prevention & control | Humans | Alzheimer Disease - drug therapy | Nootropic Agents - therapeutic use | Clinical Trials as Topic | Drug Approval | Biomarkers - blood | Research Design | Alzheimer Disease - blood | Alzheimer's disease | Drugs | Health care | Immunoglobulins | Candidates | Activities of daily living | Cognitive ability | Clinical trials | Patients | Success | Hypotheses | Alzheimers disease | Pharmaceutical industry | Dementia | Apoptosis
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3. Full Text Nanoparticulate BaTiO3 film produced by aerosol-type nanoparticle deposition
by Imanaka, Yoshihiko and Amada, Hideyuki and Kumasaka, Fumiaki and Awaji, Naoki and Kumamoto, Akihito
Journal of Nanoparticle Research, ISSN 1388-0764, 4/2016, Volume 18, Issue 4, pp. 1 - 9
Aerosol-type nanoparticle deposition (NPD) is a magical method to form a dense electroceramic film with a fine, nanoscale structure on a substrate surface by... 
Electronic Ceramics | Ceramic Film | Optics, Optoelectronics, Plasmonics and Optical Devices | Physical Chemistry | Nanoparticle | Characterization and Evaluation of Materials | Material Science | Inorganic Chemistry | Flexible Electronics | Low-temperature Process | Nanotechnology
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4. Full Text Brexpiprazole I: In vitro and in vivo characterization of a novel serotonin-dopamine activity modulator
by Maeda, Kenji and Sugino, Haruhiko and Akazawa, Hitomi and Amada, Naoki and Shimada, Jun and Futamura, Takashi and Yamashita, Hiroshi and Ito, Nobuaki and McQuade, Robert D and Mørk, Arne and Pehrson, Alan L and Hentzer, Morten and Nielsen, Vibeke and Bundgaard, Christoffer and Arnt, Jørn and Stensbøl, Tine Bryan and Kikuchi, Tetsuro
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2014, Volume 350, Issue 3, pp. 589 - 604
Brexpiprazole (OPC-34712, 7-{4-[4-(1-benzothiophen-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one) is a novel drug candidate in clinical development for... 
ATYPICAL ANTIPSYCHOTIC-DRUGS | 5-HT2A RECEPTOR ANTAGONISTS | D-3 RECEPTOR | SCHIZOAFFECTIVE DISORDER | HIGH-AFFINITY | SCHIZOPHRENIA | PHARMACOLOGY & PHARMACY | RAT-BRAIN | BINDING-SITES | PREFRONTAL CORTEX | ARIPIPRAZOLE | Cricetulus | Rats, Wistar | Humans | Male | Thiophenes - metabolism | Quinolones - pharmacology | Receptors, Dopamine D2 - metabolism | Dopamine Agents - chemistry | Dose-Response Relationship, Drug | Quinolones - chemistry | Dopamine - metabolism | Receptor, Serotonin, 5-HT1A - metabolism | CHO Cells | Cricetinae | Receptors, Dopamine D2 - agonists | Quinolones - metabolism | Rats | Thiophenes - pharmacology | Serotonin Agents - metabolism | Dopamine Agents - metabolism | Animals | Serotonin Agents - chemistry | Serotonin - metabolism | Cell Line, Tumor | Thiophenes - chemistry | Dopamine D2 Receptor Antagonists | Protein Binding - physiology
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5. Full Text Nanoparticulate BaTiO.sub.3 film produced by aerosol-type nanoparticle deposition
by Imanaka, Yoshihiko and Amada, Hideyuki and Kumasaka, Fumiaki and Awaji, Naoki and Kumamoto, Akihito
Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology, ISSN 1388-0764, 04/2016, Volume 18, Issue 4, p. 1
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s11051-016-3407-0... 
Powders | Barium | Crystals | Structure
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6. Full Text Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ 9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour
by Deiana, Serena and Watanabe, Akihito and Yamasaki, Yuki and Amada, Naoki and Arthur, Marlene and Fleming, Shona and Woodcock, Hilary and Dorward, Patricia and Pigliacampo, Barbara and Close, Steve and Platt, Bettina and Riedel, Gernot
Psychopharmacology, ISSN 0033-3158, 02/2012, Volume 219, Issue 3, pp. 859 - 873
Systemic administration | Elimination half-life | Pharmacodynamic | Rats | Phytocannabinoids | Mice | Bioavailability | Pharmacokinetic | Area under curve
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7. Full Text An artificial photosynthesis anode electrode composed of a nanoparticulate photocatalyst film in a visible light responsive GaN-ZnO solid solution system
by Imanaka, Yoshihiko and Anazawa, Toshihisa and Manabe, Toshio and Amada, Hideyuki and Ido, Sachio and Kumasaka, Fumiaki and Awaji, Naoki and Sánchez-Santolino, Gabriel and Ishikawa, Ryo and Ikuhara, Yuichi
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 35593
The artificial photosynthesis technology known as the Honda-Fujishima effect, which produces oxygen and hydrogen or organic energy from sunlight, water, and... 
HYDROGEN | TEMPERATURE | CONVERSION | MULTIDISCIPLINARY SCIENCES | EFFICIENCY | (GA1-XZNX)(N1-XOX) NANOCRYSTALS | WATER | RANGE | Electrodes | Nanoparticles | Solid solutions | Films | Energy | Tin oxide | Carbon dioxide | Tin | Sunlight | Photosynthesis | Powder | Glass substrates
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8. Full Text Brexpiprazole II: Antipsychotic-like and procognitive effects of a novel serotonin-dopamine activity modulator
by Maeda, Kenji and Lerdrup, Linda and Sugino, Haruhiko and Akazawa, Hitomi and Amada, Naoki and McQuade, Robert D and Stensbøl, Tine Bryan and Bundgaard, Christoffer and Arnt, Jørn and Kikuchi, Tetsuro
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2014, Volume 350, Issue 3, pp. 605 - 614
Brexpiprazole (OPC-34712, 7-{4-[4-(1-benzothiophen-4-yl)piperazin- 1-yl] butoxy} quinolin-2(1H)-one) is a novel serotonin-dopamine activity modulator with... 
BLINK RATE | 5-HT1A RECEPTORS | CLINICAL-TRIALS | INDUCED DEFICITS | PHENCYCLIDINE-INDUCED IMPAIRMENT | OBJECT RECOGNITION | SCHIZOPHRENIA | PHARMACOLOGY & PHARMACY | RECEPTOR OCCUPANCY | DRUG ACTION | ARIPIPRAZOLE | Motor Activity - physiology | Serotonin - physiology | Rats, Wistar | Macaca fascicularis | Motor Activity - drug effects | Rats | Receptor, Serotonin, 5-HT1A - physiology | Male | Treatment Outcome | Avoidance Learning - physiology | Cognition - drug effects | Dose-Response Relationship, Drug | Receptor, Serotonin, 5-HT2A - physiology | Animals | Dopamine - physiology | Cognition - physiology | Receptors, Dopamine D2 - physiology | Avoidance Learning - drug effects | Antipsychotic Agents - pharmacology
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9. Full Text Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
by Amada, Naoki and Yamasaki, Yuki and Williams, Claire M and Whalley, Benjamin J
PeerJ, ISSN 2167-8359, 2013, Volume 2013, Issue 1, p. e214
To date, anticonvulsant effects of the plant cannabinoid, cannabidivarin (CBDV), have been reported in several animal models of seizure. However, these... 
Cannabidivarin | Pentylenetetrazole | qPCR | Seizure | Cannabinoid | Epilepsy | MULTIDISCIPLINARY SCIENCES | Neuropeptide Y | Brain | Messenger RNA | Analysis | Genes | Seizures (Medicine) | Gene expression | Enzymes | Animal models | EGR-1 protein | Cortex | CCL3 protein | Pharmacology | Kinases | Latency | Animals | Brain research | Brain-derived neurotrophic factor | Fos protein | Rodents | Ligands | Hippocampus | Chemokines | Seizures
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10. Full Text A low mortality, high morbidity reduced intensity status epilepticus (rise) model of epilepsy and epileptogenesis in the rat
by Modebadze, Tamara and Morgan, Nicola H and Pérès, Isabelle A. A and Hadid, Rebecca D and Amada, Naoki and Hill, Charlotte and Williams, Claire and Stanford, Ian M and Morris, Christopher M and Jones, Roland S. G and Whalley, Benjamin J and Woodhall, Gavin L
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0147265
Animal models of acquired epilepsies aim to provide researchers with tools for use in understanding the processes underlying the acquisition, development and... 
ENTORHINAL CORTEX | SEIZURES | TEMPORAL-LOBE EPILEPSY | GLUTAMATE | MULTIDISCIPLINARY SCIENCES | PILOCARPINE-INDUCED EPILEPSY | SPATIAL MEMORY | RECEPTORS | DEFICITS | ELECTRICAL STIMULATION | KETAMINE | Recurrence | Rats, Wistar | Humans | Status Epilepticus - pathology | Rats | Male | Disease Progression | Morbidity | Behavior, Animal | Animals | Status Epilepticus - mortality | Status Epilepticus - epidemiology | Disease Models, Animal | Models | Prognosis | Research | Seizures (Medicine) | Status epilepticus | Seizing | Brain | Health sciences | Animal models | Epilepsy | Memory | Mortality | Lithium | Pilocarpine | Electrophysiological recording | Ethics | Convulsions & seizures | Brain research | Rodents | Pharmacy | Brain damage | Life sciences | Laboratory animals | Drug dosages | Brain injury | Seizures
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11. Full Text Limited utility of blood cultures in the management of febrile outpatient kidney transplant recipients
by Tokodai, Kazuaki and Amada, Noritoshi and Haga, Izumi and Nakamura, Atsushi and Kashiwadate, Toshiaki and kawagishi, Naoki and Ohuchi, Noriaki
Journal of Microbiology, Immunology and Infection, ISSN 1684-1182, 2015, Volume 50, Issue 5, pp. 634 - 639
Abstract Background/Purpose Blood cultures for patients suspected of having bacteremia are standard practice, although several studies demonstrate that blood... 
Infectious Disease | Medical Education | C-reactive protein | white blood cell count | blood culture | community-acquired infection | kidney transplantation | ADULT PATIENTS | INFECTIOUS DISEASES | COMMUNITY-ACQUIRED PNEUMONIA | GUIDELINES | MICROBIOLOGY | IMMUNOLOGY | WOMEN | EMERGENCY-DEPARTMENT | SERIOUS BACTERIAL-INFECTIONS | BACTEREMIA | SEVERITY | Humans | Middle Aged | Male | Kidney Transplantation | Bacteremia - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Bacteria - isolation & purification | Blood Culture - methods | Fever - blood | Outpatients | Community-Acquired Infections - drug therapy | Sensitivity and Specificity | Adult | Female | Urinary Tract Infections - microbiology | Retrospective Studies | Immunocompromised Host | Leukocyte Count - methods | C-Reactive Protein - analysis | Organ transplant recipients | Complications and side effects | Care and treatment | Transplantation | Kidneys | Bacteremia | Prevention | Medical examination
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12. Full Text CCAAT/enhancer-binding protein is epigenetically silenced by Histone Deacetylation in endometriosis and promotes the pathogenesis of endometriosis
by Kawano, Yukie and Nasu, Kaei and Hijiya, Naoki and Tsukamoto, Yoshiyuki and Amada, Kohei and Abe, Wakana and Kai, Kentaro and Moriyama, Masatsugu and Narahara, Hisashi
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 09/2013, Volume 98, Issue 9, pp. E1474 - E1482
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13. Full Text MK-801-induced deficits in social recognition in rats: reversal by aripiprazole, but not olanzapine, risperidone, or cannabidiol
by Deiana, Serena and Watanabe, Akihito and Yamasaki, Yuki and Amada, Naoki and Kikuchi, Tetsuro and Stott, Colin and Riedel, Gernot
Behavioural Pharmacology, ISSN 0955-8810, 12/2015, Volume 26, Issue 8 - Special Issue Pharmacological Approaches To The Study Of Social Behaviour - Part 3: Drug Effects On Social Behaviour, pp. 748 - 765
Deficiencies in social activities are hallmarks of numerous brain disorders. With respect to schizophrenia, social withdrawal belongs to the category of... 
cannabidiol | dizocilpine (MK-801) | rat | Social interaction | risperidone | Short-term memory | recognition | Aripiprazole | Three-chamber apparatus | DOPAMINE-D-2 RECEPTOR | three-chamber apparatus | SCHIZOPHRENIC-PATIENTS | MORRIS WATER MAZE | COGNITIVE IMPAIRMENT | short-term memory | NEUROSCIENCES | NMDA RECEPTOR ANTAGONISTS | PARTIAL AGONIST | ATYPICAL ANTIPSYCHOTIC-DRUG | aripiprazole | social interaction | SPATIAL WORKING-MEMORY | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | EQUILIBRATIVE NUCLEOSIDE TRANSPORTER | Memory - drug effects | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Benzodiazepines - pharmacology | Receptors, Dopamine D2 - agonists | Risperidone - pharmacology | Rats | Serotonin 5-HT1 Receptor Agonists - pharmacology | Cannabidiol - pharmacology | Male | Serotonin Antagonists - pharmacology | Animals | Recognition (Psychology) - drug effects | Aripiprazole - pharmacology | Dopamine Antagonists - pharmacology | Social Behavior | Models, Animal | Dizocilpine Maleate - antagonists & inhibitors | Dizocilpine Maleate - pharmacology
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14. Full Text Right versus left retroperitoneoscopic living-donor nephrectomy
by Kashiwadate, Toshiaki and Tokodai, Kazuaki and Amada, Noritoshi and Haga, Izumi and Takayama, Tetsuro and Nakamura, Atsushi and Jimbo, Takuya and Hara, Yasuyuki and kawagishi, Naoki and Ohuchi, Noriaki
International Urology and Nephrology, ISSN 0301-1623, 7/2015, Volume 47, Issue 7, pp. 1117 - 1121
To compare the safety and efficacy of right-side and left-side retroperitoneoscopic donor nephrectomy (RDN) using our hybrid technique.We retrospectively... 
Nephrology | Graft survival | Medicine & Public Health | Donor selection | Laparoscopic surgery | Living donors | Urology | Kidney transplantation | UROLOGY & NEPHROLOGY | KIDNEY | Postoperative Complications - etiology | Humans | Middle Aged | Male | Living Donors | Kidney Transplantation - methods | Nephrectomy - methods | Operative Time | Laparoscopy - methods | Laparoscopy - adverse effects | Retroperitoneal Space | Adult | Female | Retrospective Studies | Tissue and Organ Harvesting - adverse effects | Tissue and Organ Harvesting - methods | Length of Stay | Tissue and Organ Harvesting - statistics & numerical data | Japan | Nephrectomy - statistics & numerical data | Donor Selection - methods | Graft Survival | Postoperative Complications - epidemiology | Laparoscopy - statistics & numerical data | Transplant Donor Site - physiopathology | Nephrectomy - adverse effects | Laparoscopy
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15. Full Text Genomic loss of DUSP4 contributes to the progression of intraepithelial neoplasm of pancreas to invasive carcinoma
by Hijiya, Naoki and Tsukamoto, Yoshiyuki and Nakada, Chisato and Nguyen, Lam Tung and Kai, Tomoki and Matsuura, Keiko and Shibata, Kohei and Inomata, Masafumi and Uchida, Tomohisa and Tokunaga, Akinori and Amada, Kohei and Shirao, Kuniaki and Yamada, Yasunari and Mori, Hiromu and Takeuchi, Ichiro and Seto, Masao and Aoki, Masahiro and Takekawa, Mutsuhiro and Moriyama, Masatsugu
Cancer Research, ISSN 0008-5472, 05/2016, Volume 76, Issue 9, pp. 2612 - 2625
The progression from precursor lesions of pancreatic cancer, including pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasm (IPMN),... 
Oligonucleotide Array Sequence Analysis | Adenocarcinoma, Mucinous - pathology | Humans | Adenocarcinoma, Papillary - genetics | Transcriptome | Carcinoma, Pancreatic Ductal - genetics | Heterografts | Dual-Specificity Phosphatases - genetics | Carcinoma, Pancreatic Ductal - mortality | Pancreatic Neoplasms - mortality | Adenocarcinoma, Papillary - pathology | Adenocarcinoma in Situ - pathology | Adenocarcinoma in Situ - genetics | Dual-Specificity Phosphatases - metabolism | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | Kaplan-Meier Estimate | Pancreatic Neoplasms - genetics | Adenocarcinoma, Papillary - mortality | Carcinoma, Pancreatic Ductal - pathology | Mitogen-Activated Protein Kinase Phosphatases - genetics | Disease Progression | Adenocarcinoma, Mucinous - mortality | Microscopy, Confocal | Animals | Comparative Genomic Hybridization | Mice | Adenocarcinoma, Mucinous - genetics | Mitogen-Activated Protein Kinase Phosphatases - metabolism
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16. Anticonvulsant potential of the phytocannabinoid, cannabidivarin, on epilepsy disease progression
by Amada, Naoki
2014
Epilepsy affects about 0.8% of individuals [1]. Many treatments are available but more effective and better-tolerated antiepileptic drugs (AEDs) with new... 
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17. Full Text Pretransplant HbA1c is a useful predictor for the development of new-onset diabetes in renal transplant recipients receiving no or low-dose erythropoietin
by Tokodai, Kazuaki and Amada, Noritoshi and Haga, Izumi and Nakamura, Atsushi and Kashiwadate, Toshiaki and Kawagishi, Naoki and Ohuchi, Noriaki
International Journal of Endocrinology, ISSN 1687-8337, 2014, Volume 2014, pp. 436725 - 7
Aims. To evaluate the predictive power of pretransplant HbA1c for new-onset diabetes after transplantation (NODAT) in kidney transplant candidates, who had... 
GLYCATED HEMOGLOBIN | SURVIVAL | HBA(1C) | FASTING PLASMA-GLUCOSE | GLYCEMIC CONTROL | LIFE-STYLE | TOLERANCE TEST | ENDOCRINOLOGY & METABOLISM | PATIENT | MELLITUS | GLYCOSYLATED HEMOGLOBIN | Prevention | Complications and side effects | Kidneys | Erythropoietin | Physiological aspects | Genetic aspects | Transplantation | Diabetes | Research | Risk factors
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