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performing operations (16) 16
transporting (16) 16
arrangement or mounting of plural diverse prime-movers invehicles (15) 15
arrangement or mounting of propulsion units or oftransmissions in vehicles (15) 15
arrangements in connection with cooling, air intake, gasexhaust or fuel supply of propulsion units, in vehicles (15) 15
auxiliary drives for vehicles (15) 15
climate change mitigation technologies related totransportation (15) 15
conjoint control of vehicle sub-units of different type ordifferent function (15) 15
control systems specially adapted for hybrid vehicles (15) 15
electric equipment or propulsion of electrically-propelledvehicles (15) 15
electrodynamic brake systems for vehicles, in general (15) 15
general tagging of cross-sectional technologies spanning over several sections of the ipc (15) 15
general tagging of new technological developments (15) 15
instrumentation or dashboards for vehicles (15) 15
magnetic suspension or levitation for vehicles (15) 15
road vehicle drive control systems for purposes not related tothe control of a particular sub-unit (15) 15
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (15) 15
technologies or applications for mitigation or adaptation againstclimate change (15) 15
vehicles in general (15) 15
blasting (12) 12
combustion engines (12) 12
controlling combustion engines (12) 12
heating (12) 12
hot-gas or combustion-product engine plants (12) 12
lighting (12) 12
mechanical engineering (12) 12
weapons (12) 12
gastroenterology and hepatology (10) 10
acetaldehyde (8) 8
humans (8) 8
starting aids for such engines, not otherwise providedfor (8) 8
starting of combustion engines (8) 8
animals (7) 7
cancer (7) 7
esophageal cancer (7) 7
esophageal squamous cell carcinoma (7) 7
index medicus (7) 7
squamous cell carcinoma (7) 7
dna damage (5) 5
esophagus (5) 5
male (5) 5
oncology (5) 5
risk (5) 5
arrangement of braking elements on vehicles in general (4) 4
brake control systems or parts thereof, in general (4) 4
brakes (4) 4
clutches (4) 4
couplings for transmitting rotation (4) 4
dna (4) 4
engineering elements and units (4) 4
gastroenterology & hepatology (4) 4
gearing (4) 4
general measures for producing and maintaining effectivefunctioning of machines or installations (4) 4
land vehicles for travelling otherwise than on rails (4) 4
mice (4) 4
motor vehicles (4) 4
portable devices for preventing unwanted movement ofvehicles (4) 4
squamous-cell carcinoma (4) 4
technical subjects covered by former uspc (4) 4
technical subjects covered by former uspc cross-reference artcollections [xracs] and digests (4) 4
thermal insulation in general (4) 4
trailers (4) 4
vehicle brake control systems or parts thereof (4) 4
vehicle modifications to facilitate cooling of brakes (4) 4
adducts (3) 3
alcohol (3) 3
alcohol-consumption (3) 3
carcinogenesis (3) 3
carcinoma, squamous cell - pathology (3) 3
chemotherapy (3) 3
endoscopic mucosal resection (3) 3
endoscopy (3) 3
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esophageal neoplasms - pathology (3) 3
female (3) 3
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acetaldehyde - toxicity (2) 2
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aged, 80 and over (2) 2
alcohol drinking - adverse effects (2) 2
aldehyde dehydrogenase (2) 2
aldehyde dehydrogenase 2 (2) 2
aldehyde dehydrogenase genotypes (2) 2
aldehydes (2) 2
article (2) 2
biochemistry & molecular biology (2) 2
biomarkers, tumor - genetics (2) 2
carcinoma, squamous cell - epidemiology (2) 2
carcinoma, squamous cell - etiology (2) 2
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Nature, ISSN 0028-0836, 01/2019, Volume 565, Issue 7739, pp. 312 - 317
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 7, pp. 1700 - 1715
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive squamous cell carcinomas and is highly prevalent in Asia. Alcohol and its metabolite,... 
Gastroenterology and Hepatology | Field Cancerization | Genetic Polymorphism | Squamous Differentiation | Aldehyde Dehydrogenase 2 | Acetaldehyde | DNA-ADDUCTS | ENDOSCOPIC MUCOSAL RESECTION | HUMAN-PAPILLOMAVIRUS | PHASE-III TRIAL | GROWTH-FACTOR RECEPTOR | TO-MESENCHYMAL TRANSITION | EPITHELIAL-CELLS | NEOADJUVANT CHEMOTHERAPY | CISPLATIN PLUS FLUOROURACIL | DEFINITIVE CHEMORADIOTHERAPY | GASTROENTEROLOGY & HEPATOLOGY | Smoking - adverse effects | Predictive Value of Tests | Life Style | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Humans | Esophageal Neoplasms - epidemiology | Esophageal Neoplasms - pathology | Cell Transformation, Neoplastic - genetics | Esophageal Neoplasms - metabolism | Biomarkers, Tumor - metabolism | Papillomavirus Infections - virology | Esophageal Neoplasms - therapy | Esophageal Squamous Cell Carcinoma | Genetic Predisposition to Disease | Signal Transduction | Carcinoma, Squamous Cell - epidemiology | Papillomavirus Infections - epidemiology | Risk Factors | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Combined Modality Therapy | Alcohol Drinking - adverse effects | Cell Transformation, Neoplastic - metabolism | Esophageal Neoplasms - virology | Animals | Esophageal Neoplasms - genetics | Alcohol Drinking - epidemiology | Smoking - epidemiology | Biomarkers, Tumor - genetics | Cell Transformation, Neoplastic - pathology | Neoplasm Staging | Medical research | Enzymes | Squamous cell carcinoma | PET imaging | Genomics | Clinical trials | Cell differentiation | Genetic polymorphisms | Fanconi's anemia | Chemotherapy | Metabolites | Medicine, Experimental | Endoscopy | Tumor proteins | Health aspects | Esophageal cancer | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 1943
Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA, including DNA adducts, single- and/or double-strand breaks (DSBs), point... 
Cancer development | DNA damage | DNA adduct | Esophageal squamous cell carcinoma | Head and neck squamous cell carcinoma | Acetaldehyde | DNA repair pathway | esophageal squamous cell carcinoma | HUMAN-LYMPHOCYTES | ALDEHYDE DEHYDROGENASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEHYDROGENASE GENE POLYMORPHISMS | ALCOHOL-CONSUMPTION | cancer development | FANCONI-ANEMIA | CHEMISTRY, MULTIDISCIPLINARY | CELL CARCINOMA | NECK-CANCER | DNA CROSS-LINKS | acetaldehyde | ESOPHAGEAL CANCER | head and neck squamous cell carcinoma | SISTER-CHROMATID EXCHANGES | Esophageal Neoplasms - etiology | Head and Neck Neoplasms - prevention & control | Acetaldehyde - metabolism | Ethanol - metabolism | Acetaldehyde - toxicity | Humans | Carcinogenesis - genetics | Esophageal Neoplasms - prevention & control | Carcinoma, Squamous Cell - prevention & control | Carcinogenesis - metabolism | Carcinoma, Squamous Cell - etiology | Animals | Head and Neck Neoplasms - etiology | Ethanol - adverse effects | DNA Damage | Alcohol | Aldehydes | Damage prevention | Carcinogenesis | DNA repair | Epidemiology | Aldehyde dehydrogenase | Carcinogens | Head and neck | Neck | Beverages | Deoxyribonucleic acid--DNA | Adducts | Squamous cell carcinoma | Anemia | Crosslinking | Epithelium | Fanconi syndrome | Metabolism | Esophagus | Molecular modelling | Deoxyguanosine | Alcoholic beverages | Mutation | DNA adducts | Cancer
Journal Article
Diseases of the Esophagus, ISSN 1120-8694, 09/2018, Volume 31, Issue Supplement_1, pp. 130 - 131
Journal Article
Diseases of the Esophagus, ISSN 1120-8694, 09/2018, Volume 31, Issue Supplement_1, pp. 129 - 129
Journal Article
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 08/2017, Volume 36, Issue 1, pp. 101 - 13
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2016, Volume 150, Issue 4, pp. S367 - S367
Journal Article
Nippon Laser Igakkaishi, ISSN 0288-6200, 04/2019, Volume 40, Issue 1, pp. 57 - 61
Journal Article
Carcinogenesis, ISSN 0143-3334, 05/2019
Alcohol consumption is the key risk factor for the development of esophageal squamous cell carcinoma (ESCC), and acetaldehyde, a metabolite of alcohol, is an... 
Journal Article
Gastroenterology, ISSN 0016-5085, 2016, Volume 151, Issue 5, pp. 860 - 869.e7
Background & Aims Some patients develop multiple squamous cell carcinomas (SCCs) in the upper aerodigestive tract, attributed to field cancerization; alcohol... 
Gastroenterology and Hepatology | Drinking Alcohol | Genetics Methods | Risk Factor | Carcinogenesis | ENDOSCOPIC MUCOSAL RESECTION | SUBMUCOSAL DISSECTION | CANCER | REGION | ALDEHYDE DEHYDROGENASE GENOTYPES | PATTERN | LUGOL-VOIDING LESIONS | MEN | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | Esophageal Neoplasms - etiology | Optical Imaging | Prospective Studies | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Carcinoma, Squamous Cell - diagnostic imaging | Neoplasms, Multiple Primary - diagnostic imaging | Esophageal Neoplasms - epidemiology | Esophageal Neoplasms - pathology | Esophagoscopy | Incidence | Neoplasm Grading | Head and Neck Neoplasms - epidemiology | Aged, 80 and over | Adult | Esophagus - diagnostic imaging | Female | Esophageal Squamous Cell Carcinoma | Neoplasms, Multiple Primary - etiology | Carcinoma, Squamous Cell - epidemiology | Head and Neck Neoplasms - diagnostic imaging | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Alcohol Abstinence | Neoplasms, Multiple Primary - epidemiology | Neoplasms, Multiple Primary - pathology | Alcohol Drinking - adverse effects | Head and Neck Neoplasms - pathology | Neoplasms, Second Primary - epidemiology | Neoplasms, Second Primary - etiology | Carcinoma, Squamous Cell - etiology | Esophagus - pathology | Head and Neck Neoplasms - etiology | Aged | Neoplasms, Second Primary - diagnostic imaging | Longitudinal Studies | Neoplasms, Second Primary - pathology | Esophageal Neoplasms - diagnostic imaging | Smoking Cessation | Medical colleges | Squamous cell carcinoma | Oncology, Experimental | Research | Endoscopy | Drinking of alcoholic beverages | Esophageal cancer | Risk factors | Cancer
Journal Article
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, ISSN 2155-384X, 06/2017, Volume 8, Issue 6, pp. e96 - e96
OBJECTIVES: Acetaldehyde, the first metabolite of ethanol, is a definite carcinogen for the esophagus, head, and neck; and aldehyde dehydrogenase 2 (ALDH2) is... 
HUMAN-LYMPHOCYTES | ALDEHYDE DEHYDROGENASE GENOTYPES | GENETIC-POLYMORPHISM | ACETALDEHYDE CONCENTRATIONS | SQUAMOUS-CELL CARCINOMA | RISK | ETHANOL | JAPANESE ALCOHOLIC MEN | ESOPHAGEAL | GASTROENTEROLOGY & HEPATOLOGY | LIVER ALCOHOL | Breath tests | Genotype & phenotype | Aldehydes | Esophagus | Original Communication
Journal Article