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Journal of Clinical Investigation, ISSN 0021-9738, 09/2012, Volume 122, Issue 9, pp. 3281 - 3294
CD4 T follicular helper (TFH) cells interact with and stimulate the generation of antigen-specific B cells. TFH cell interaction with B cells correlates with... 
BINDING PROTEIN-ALPHA | MEDICINE, RESEARCH & EXPERIMENTAL | GERMINAL CENTER B | C/EBP-ALPHA | ACTIVATION | COLONY-STIMULATING FACTOR | PROLIFERATION ARREST | IMMUNE-RESPONSES | IMMUNODEFICIENCY VIRUS-INFECTION | RECEPTOR | DIFFERENTIATION | Cell Proliferation | Lymph Nodes - pathology | Oligonucleotide Array Sequence Analysis | Transcriptome | Macaca mulatta | Antibodies, Viral - blood | T-Lymphocytes, Helper-Inducer - immunology | Cell Death | Receptors, Lysosphingolipid - genetics | Receptors, Lysosphingolipid - metabolism | Simian Acquired Immunodeficiency Syndrome - pathology | B-Lymphocytes - metabolism | Simian Immunodeficiency Virus - immunology | Gene Expression | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Proto-Oncogene Proteins c-maf - genetics | Lymph Nodes - metabolism | Lymph Nodes - virology | Germinal Center - pathology | Transcription Factors - genetics | Simian Acquired Immunodeficiency Syndrome - blood | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Simian Immunodeficiency Virus - physiology | Host-Pathogen Interactions | Transcription Factors - metabolism | Animals | B-Lymphocytes - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Germinal Center - virology | Proto-Oncogene Proteins c-maf - metabolism | CD4 Antigens - metabolism | Genetic aspects | Research | Simian immunodeficiency virus | Gene expression | CD4 lymphocytes
Journal Article
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 05/2017, Volume 46, Issue 5, pp. 777 - 791.e10
Most HIV-1-specific neutralizing antibodies isolated to date exhibit unusual characteristics that complicate their elicitation. Neutralizing antibodies that... 
V1V2 | antibody | bnAb | HIV | trimer | neutralization | glycan shield | VLP | B cell ontogeny | CDRH3 | vaccine-design template | NAb | CONFORMATIONAL EPITOPE | RECOGNITION | BROAD | FUSION PEPTIDE | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | IDENTIFICATION | REVEAL | ELECTRON-MICROSCOPE | QUATERNARY | ENVELOPE TRIMERS | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Protein Multimerization | Antibodies, Neutralizing - metabolism | Vaccines, Virus-Like Particle - metabolism | Phylogeny | HIV Envelope Protein gp120 - metabolism | Vaccines, Virus-Like Particle - chemistry | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Complementarity Determining Regions - chemistry | Peptide Fragments - immunology | Protein Interaction Domains and Motifs | HIV Envelope Protein gp120 - chemistry | Binding Sites | B-Lymphocytes - metabolism | HIV Antibodies - metabolism | Amino Acid Sequence | Peptide Fragments - metabolism | HIV Infections - virology | Models, Molecular | HIV Antibodies - chemistry | HIV-1 - immunology | Peptide Fragments - chemistry | B-Lymphocytes - immunology | Antibodies, Neutralizing - chemistry | Complementarity Determining Regions - immunology | Protein Binding | Protein Conformation | Vaccines, Virus-Like Particle - immunology | Viral antibodies | Medical research | Crystals | Medicine, Experimental | Antibodies | Research institutes | Structure | HIV (Viruses) | Immunoglobulins | Recombination | Particulates | Viruses | Vaccines | Virus-like particles | Lymphocytes B | Plasmids | Human immunodeficiency virus--HIV | Probes | Binding sites | Crystal structure
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2019, Volume 20, Issue 3, pp. 362 - 372
The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes... 
SYSTEM | DESIGN | ANTIBODY RECOGNITION | ANTIGENIC STRUCTURE | VACCINE | BEAM-INDUCED MOTION | IMMUNOLOGY | NEUTRALIZING EPITOPE | GLOBULAR HEAD | STEM | Influenza A Virus, H1N1 Subtype - immunology | Orthomyxoviridae Infections - prevention & control | Antibodies, Neutralizing - administration & dosage | Influenza Vaccines - administration & dosage | Nanoparticles - chemistry | Humans | Influenza A Virus, H1N1 Subtype - physiology | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Antibodies, Neutralizing - immunology | B-Lymphocytes - virology | Female | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - metabolism | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Immunization | Cross Reactions - immunology | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Influenza Vaccines - immunology | Influenza Vaccines - chemistry | Antibodies, Viral - immunology | Cross Reactions - drug effects | Mice, Inbred BALB C | Influenza, Human - prevention & control | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Influenza viruses | Influenza vaccines | Monoclonal antibodies | B cells | Immunity | Influenza | Viral antibodies | Nanoparticles | Composition | Immune response | Antibodies | Glycoproteins | Research | Health aspects | Immunological research | Antigens | Discordance | Admixtures | Viruses | Vaccines | Immunodominance | Lymphocytes B | Hemagglutinins | Avidity | Strains (organisms)
Journal Article
Immunity, ISSN 1074-7613, 2004, Volume 21, Issue 6, pp. 793 - 803
Journal Article
Nature Biotechnology, ISSN 1087-0156, 02/2018, Volume 36, Issue 2, pp. 152 - 155
Journal Article
Journal of experimental medicine, ISSN 0022-1007, 2010, Volume 207, Issue 13, pp. 2869 - 2881
Journal Article