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BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 10/2013, Volume 1829, Issue 10, pp. 981 - 986
DNA and histone chromatin modifying enzymes play a crucial role in chromatin remodeling in several biological processes. Lysine-specific demethylase 1 (LSD1),... 
Histone modification | Chromatin | Stem cell | LSD1 | Cancer | LYSINE-SPECIFIC-DEMETHYLASE-1 | METHYLATION | NETWORK | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | PLURIPOTENCY | BIOPHYSICS | TAL1 FUNCTION | DNA OXIDATION | REGULATORY CIRCUITRY | GENE ACTIVATION | PROTEINS | Enzymes | Embryonic development | Development and progression | Genetic transcription
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56592
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 324
Studies of alterations in histone methylation in cancer have led to the identification of histone methyltransferases and demethylases as novel targets for... 
Epigenetics | Histone demethylase | LncRNAs | LSD1 | Cancer | lncRNAs | EXERTS ONCOGENIC PROPERTIES | CELL-PROLIFERATION | LNCRNA HOTAIR | E-CADHERIN | histone demethylase | epigenetics | EPITHELIAL-MESENCHYMAL TRANSITION | TERRA | PROMOTES PROLIFERATION | LONG NONCODING RNA | ONCOLOGY | EPIGENETIC REGULATION | cancer | BINDING
Journal Article
Cell Cycle, ISSN 1538-4101, 08/2010, Volume 9, Issue 15, pp. 3074 - 3076
Myc oncogene is a transcription factor that contributes to the genesis of a wide variety of tumors by regulating proliferation, differentiation and apoptosis.... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Transcription | Histone | Methylation | Myc | Oxidative burst | oxidative burst | transcription | MECHANISM | methylation | LSD1 | C-MYC | histone | CELL BIOLOGY | Animals | Oxidation-Reduction | Models, Biological | Humans | DNA Repair Enzymes - metabolism | Transcription, Genetic | DNA - metabolism | Proto-Oncogene Proteins c-myc - metabolism
Journal Article
Cell Cycle, ISSN 1538-4101, 08/2007, Volume 6, Issue 16, pp. 2031 - 2037
Journal Article
Cell death & disease, ISSN 2041-4889, 06/2017, Volume 8, Issue 6, pp. e2842 - e2842
Mitochondria are the powerhouses of energy production and the sites where metabolic pathway and survival signals integrate and focus, promoting adaptive... 
ANCHOR PROTEIN | ACTIVATION | COMPLEX | SIGNALING PATHWAY | C-MYC | DEPENDENT PROTEIN-KINASE | STRESS | OXIDATIVE-METABOLISM | CANCER | CAMP | CELL BIOLOGY | Neoplasm Transplantation | RNA, Small Interfering - genetics | Cell Proliferation | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Lung Neoplasms - mortality | Neuroglia - pathology | Lung Neoplasms - metabolism | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | Brain Neoplasms - metabolism | A Kinase Anchor Proteins - genetics | TOR Serine-Threonine Kinases - genetics | Mitochondria - genetics | Transcription, Genetic | Nuclear Proteins - genetics | A Kinase Anchor Proteins - metabolism | Lung Neoplasms - genetics | A Kinase Anchor Proteins - antagonists & inhibitors | Signal Transduction | Brain Neoplasms - genetics | Epithelial Cells - pathology | Nuclear Proteins - metabolism | Mitochondria - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Animals | Mice, Nude | Survival Analysis | Cell Line, Tumor | Protein Binding | Neuroglia - metabolism | Proto-Oncogene Proteins c-myc - genetics | RNA, Small Interfering - metabolism | TOR protein | Phosphorylation | Integration | Cell survival | Transcription | Oxidative metabolism | Lung cancer | Glioblastoma | Cyclic AMP | Rapamycin | Myc protein | Leucine | Src protein | Metabolism | Survival | Signal transduction | Mitochondria | Nutrient availability | Tumorigenesis | Cancer | Original
Journal Article
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 05/2019, Volume 1862, Issue 5, pp. 535 - 546
Senescence is a stress-responsive cellular program that leads to cell cycle arrest. In cancer cells, senescence has profound implications for tumor... 
mTOR | Senescence | HIF-1α | KDM1A | LSD1 | Glioblastoma | HIF-1 alpha | BIOCHEMISTRY & MOLECULAR BIOLOGY | MESENCHYMAL TRANSITION | CELLULAR SENESCENCE | HIF1-ALPHA | HYPOXIA-INDUCIBLE FACTORS | THERAPY | BIOPHYSICS | METABOLISM | ROLES | GROWTH | LSD1/KDM1A | PROMOTES
Journal Article