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Immunity, ISSN 1074-7613, 02/2017, Volume 46, Issue 2, pp. 197 - 204
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2014, Volume 371, Issue 15, pp. 1426 - 1433
After a prolonged response, an anaplastic thyroid cancer developed resistance to mammalian target of rapamycin (mTOR) inhibition by somatic mutation of mTOR at... 
MEDICINE, GENERAL & INTERNAL | ACTIVATION | MTOR MUTATIONS | PROTEIN | LYMPHANGIOLEIOMYOMATOSIS | INHIBITION | TUBEROUS SCLEROSIS COMPLEX | ANGIOMYOLIPOMA | GENE-PRODUCTS | SENSITIVITY | SIROLIMUS | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Humans | Middle Aged | Thyroid Neoplasms - diagnostic imaging | Thyroid Carcinoma, Anaplastic | Antineoplastic Agents - therapeutic use | Combined Modality Therapy | Neoplasm Recurrence, Local - pathology | Radiography | Thyroid Neoplasms - therapy | Thyroid Neoplasms - genetics | Drug Resistance, Neoplasm - genetics | TOR Serine-Threonine Kinases - genetics | Neoplasm Recurrence, Local - diagnostic imaging | TOR Serine-Threonine Kinases - chemistry | Lymphatic Metastasis - pathology | Tumor Suppressor Proteins - genetics | Female | Protein Conformation | Mutation | Everolimus | Thyroid Neoplasms - pathology | Thyroid cancer | Research | Drug therapy | Patient outcomes | TOR protein | Tuberous sclerosis 2 protein | Nonsense mutation | Genomes | Metastasis | Drug resistance | Kinases | Cancer therapies | Metastases | Thyroid carcinoma | Proteins | Allosteric properties | Deoxyribonucleic acid--DNA | Crystal structure | Thyroid | Rapamycin | FDA approval | Radiation therapy | Patients | Studies | TSC2 protein | Chemotherapy | Womens health | Biopsy | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 4, pp. 857 - 865
Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome... 
Journal Article
Nature Biotechnology, ISSN 1087-0156, 2014, Volume 32, Issue 7, pp. 644 - 652
Molecular profiling of tumors promises to advance the clinical management of cancer, but the benefits of integrating molecular data with traditional clinical... 
CELL LUNG-CANCER | SURVIVAL | BIOMARKERS | SUPPRESSOR | EVEROLIMUS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | VALIDATION | RESISTANCE | MUTATIONS | EXPRESSION | BREAST | Clinical trials | Genetic aspects | Research | Methods | Proteomics | Cancer | Oncology | Genomics | Medical prognosis | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2016, Volume 540, Issue 7631, pp. 114 - 118
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1564 - 1564
Journal Article
Genome Medicine, ISSN 1756-994X, 07/2016, Volume 8, Issue 1, pp. 79 - 79
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2017, Volume 23, Issue 12, pp. 3214 - 3222
Journal Article
Nature, ISSN 0028-0836, 2019, Volume 569, Issue 7757, pp. 503 - 503
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0178189 - e0178189
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1010 - 1010
Journal Article
Journal Article