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Journal Article
Journal Article
Letters in Drug Design and Discovery, ISSN 1570-1808, 2016, Volume 13, Issue 1, pp. 64 - 76
A series of 6,7-disubstituted-3-{2-[4-(substituted) piperazin-1-yl]-2-oxoethyl}quinazoline-2,4(1H, 3H)-dione derivatives (7-34) were synthesized and their... 
Cytotoxicity | Sulforhodamine B method | Quinazoline | Anticancer | Quinazoline-2,4(1H,3H)-dione | Piperazine | SUBSTITUTED QUINAZOLINEDIONES | DESIGN | CHEMISTRY, MEDICINAL | AMPA | PROTEIN | piperazine | sulforhodamine B method | ANTICONVULSANT | anticancer | QUINAZOLINE-2,4-DIONE | IN-VITRO | DNA GYRASE | INHIBITORS | TOPOISOMERASE-IV | cytotoxicity | quinazoline-2,4(1H,3H)-dione
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11021 - 11036
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a... 
CHEMISTRY, MEDICINAL | MODIFIERS | IDENTIFICATION | SINGLE NUCLEOTIDE
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2016, Volume 59, Issue 10, pp. 4926 - 4947
Journal Article
Synthesis (Stuttgart), ISSN 0039-7881, 11/2016, Volume 48, Issue 21, pp. 3701 - 3712
A fast and efficient synthesis of libraries of positional isomeric 1H-tetrazoles and 5H-tetrazoles, for the purpose of testing binding hypothesis of isomeric... 
n butyl 2 (1h tetrazol 5 yl)acetamide | unclassified drug | n dodecyl 2 (1h tetrazol 5 yl)acetamide | n (4 chlorobenzyl) 2 (1h tetrazol 5 yl)acetamide | n (3 phenylpropyl) 2 (1h tetrazol 5 yl)acetamide | n (2 hydroxy 2 phenylethyl) 2 (1h tetrazol 5 yl)acetamide | n (4 fluorobenzyl) 2 isocyanoacetamide | isocyano acetamide | 2 isocyano n (1 phenylethyl)acetamide | 5h tetrazole | precipitation | cyanoacetamide | n (2,2 diphenylethyl) 2 (1h tetrazol 5 yl)acetamide | 5 H -tetrazole | 1 H -tetrazole | n (3,4 dimethoxybenzyl) 2 (1h tetrazol 5 yl)acetamide | temperature | n (naphthalen 2 ylmethyl) 2 (1h tetrazol 5 yl)acetamide | [2+3] cycloaddition | n (4 fluorobenzyl) 2 (1h tetrazol 5 yl)acetamide | n cyclopropyl 2 (1h tetrazol 5 yl)acetamide | n (4 phenylbutyl) 2 (1h tetrazol 5 yl)acetamide | n phenethyl 2 (1h tetrazol 5 yl)acetamide | synthesis | Oliveri-Mandala and Alagna reaction | n cyclohexyl 2 (1h tetrazol 5 yl)acetamide | 1 morpholino 2 (1h tetrazol 5 yl)ethan 1 one | n (4 chlorobenzyl) 2 isocyanoacetamide | n benzyl 2 isocyanoacetamide | tetrazole derivative | 2 (1h tetrazol 5 yl) n [1 (para tolyl)ethyl]acetamide | n allyl 2 (1h tetrazol 5 yl)acetamide | 1h tetrazole | 2 (1h tetrazol 5 yl) n [2 (thiophen 2 yl)ethyl]acetamide | n (furan 2 ylmethyl) 2 (1h tetrazol 5 yl)acetamide | article | n [1 (4 chlorophenyl)ethyl] 2 (1h tetrazol 5 yl)acetamide | fragment-based drug discovery | cycloaddition | n benzyl 2 (1h tetrazol 5 yl)acetamide | reaction time | 1 (pyrrolidin 1 yl) 2 (1h tetrazol 5 yl)ethan 1 one | unindexed drug | substitution reaction | n (4 fluorophenethyl) 2 (1h tetrazol 5 yl)acetamide | chemical binding | paper | 5H-tetrazole | NITRILES | CHEMISTRY, ORGANIC | 1H-tetrazole | isocyanoacetamide
Journal Article
Synthesis (Stuttgart), ISSN 0039-7881, 2016, Volume 48, Issue 8, pp. 1122 - 1130
We describe the hitherto unknown use of N-Boc-protected hydrazine in the Ugi tetrazole reaction to access a library of highly substituted... 
tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 methylbutyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 methyl 1 (1 phenethyl 1h tetrazol 5 yl)propyl]hydrazine 1 carboxylic acid | unclassified drug | proton transport | Ugi reaction | Ugi tetrazole reaction | tert butyl 2[1 (1 tert butyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | hydrazine | drug isolation | electrospray mass spectrometry | isocyanides | benzyl 4 [2 (tert butoxycarbonyl)hydrazino] 4[1 [2 (1h indol 3 yl)ethyl] 1h tetrazol 5 yl]piperidine 1 carboxylic acid | deprotection reaction | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 phenylethyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (1 methoxy 4 methyl 1 oxopentan 2 yl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | mass spectrometry | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 methylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl(1 cyclohexyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | proton nuclear magnetic resonance | hydrazine derivative | drug screening | chemical reaction | supercritical fluid chromatography | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl)(cyclohexyl)methyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 phenethyl 1h tetrazol 5 yl)cyclohexyl]hydrazine 1 carboxylic acid | article | carbon nuclear magnetic resonance | To be checked by Faculty | tert butyl 2 [3 methyl 1 (1 phenethyl 1h tetrazol 5 yl)butyl]hydrazine 1 carboxylic acid | one pot synthesis | tetrazoles | tert butyl 2 [1 chloro 2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]butan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [1 [1 benzyl 4 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]piperidin 4 yl]]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl (1 phenethyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | multicomponent reaction | tert butyl 2 [2 chloro 1 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]ethyl]hydrazine 1 carboxylic acid | paper | 3-COMPONENT REACTION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | MULTICOMPONENT REACTIONS | DIASTEREOSELECTIVE SYNTHESIS | CHEMISTRY | DIVERSITY | LEWIS-ACIDS | 4-COMPONENT CONDENSATION | EFFICIENT
Journal Article
DALTON TRANSACTIONS, ISSN 1477-9226, 01/2018, Volume 47, Issue 4, pp. 1003 - 1009
.... The vast majority of these complexes feature a linear uranyl group (e.g., O-yl-U-O-yl = 180 degrees); however, there are a handful of complexes that feature much more acute O-yl-U-O-yl angles... 
URANIUM | INFRARED-SPECTRA | CIS-DIOXIDO URANYL | CRYSTAL-STRUCTURE | BETA-DIKETONES | STRUCTURAL-CHARACTERIZATION | COORDINATION | ACTINIDE CHEMISTRY | LIGAND | F-ELEMENT COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | Chemistry
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 06/2015, Volume 23, Issue 11, pp. 2699 - 2715
[Display omitted] Scaffold diversity is key in the ongoing exercise of discovery of novel bioactive compounds using high throughput screening (HTS). Based on... 
Synthesis | Tetrazol | Parallel | Isocyanide | Ugi | Pictet–Spengler | unclassified drug | n [[(4 chlorophenyl)[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]methyl] 2 3,4 dimethoxyphenyl]ethanamine | 8 ethyl 2,3 dimethoxy 8 methyl 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | n [2 (1h indol 3 yl)ethyl] 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]propan 1 amine | tetracyclic tetrazole scaffold | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)cyclohexanamine | n [[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl](4 fluorophenyl)methyl] 2 (3,4 dimethoxy phenyl)ethanamine | 8 (4 chlorophenyl) 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 isopropyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 phenylethanamine | high throughput screening | mass spectrometry | Pictet-Spengler | multicomponent reaction chemistry | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)propan 1 amine | thin layer chromatography | 1 benzyl 4 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxy phenethyl)piperidin 4 amine | proton nuclear magnetic resonance | n [2 (1h indol 3 yl)ethyl] 1 benzyl 4 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]piperidin 4 amine | 2,3 dimethoxy 8 phenyl 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 7',12',12b',13' tetrahydro 6'h spiro[cyclohexane 1,4' tetrazolo[1'',5'' 4',5']pyrazino[1',2' 1,2]pyrido[3,4 b]indole] | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 phenylpropan 1 amine | 2,3 dimethoxy 8 phenethyl 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | chemical reaction | supercritical fluid chromatography | tetrazole derivative | n [2 (1h indol 3 yl)ethyl] 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]cyclohexanamine | article | carbon nuclear magnetic resonance | n [[1,1' biphenyl] 4 yl[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]methyl] 2 (3,4 dimethoxyphenyl)ethanamine | controlled study | 8 (4 fluorophenyl) 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 benzyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 ethyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 methylpropan 1 amine | 8 [[1,1' biphenyl] 4 yl] 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 benzyl 2',3'dimethoxy 5',6',13',13a' tetrahydrospiro[piperidine 4,8' tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline] | 4 ethyl 4,6,7,12,12b,13 hexahydro tetrazolo[1'',5'' 4',5']pyrazino[1',2' 1,2]pyrido[3,4 b]indole | 2',3'dimethoxy 5',6',13',13a' tetrahydrospiro[cyclohexane 1,8' tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline] | unindexed drug | pharmacophore | n [[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl](phenyl)methyl] 2 (3,4 dimethoxy phenyl)ethanamine | 2 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)butan 2 amine | CHEMISTRY, MEDICINAL | ONE-POT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | PRAZIQUANTEL | LIBRARIES | MULTICOMPONENT REACTIONS | CHEMISTRY | DIVERSITY | EFFICIENT | DERIVATIVES | Models, Molecular | Molecular Structure | Tetrazoles - chemical synthesis | Polycyclic Compounds - chemical synthesis | Drug Discovery | Pictet-spengler
Journal Article
Australian journal of chemistry, ISSN 0004-9425, 2017, Volume 70, Issue 5, pp. 468 - 477
The reaction of 1-(4,2′:6′,4″-terpyridin-4′-yl)ferrocene (2) with ZnI2 leads to [{ZnI2(2)}4·1.4MeOH·0.8H2O] which contains a discrete... 
POLYMERS | DESIGN | METALLOMACROCYCLES | LIGANDS | LINKERS | CRYSTAL-STRUCTURES | BUILDING-BLOCK | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | METAL-COMPLEXES
Journal Article
Acta Crystallographica Section E: Structure Reports Online, ISSN 1600-5368, 2009, Volume 65, Issue 11, pp. o2948 - U2600
In the title compound, C28H30ClNO2, the cyclopentane ring adopts an envelope conformation. In the crystal structure, molecules are linked by intermolecular O-H... 
SCHIFF-BASES | CRYSTALLOGRAPHY | COMPLEXES
Journal Article
Journal of polymer science. Part A, Polymer chemistry, ISSN 1099-0518, 2019, Volume 57, Issue 13, pp. 1478 - 1485
ABSTRACT A series of novel donor–acceptor (D–A) random conjugated terpolymers P2‐P4 along with the homopolymers P1 (BDT‐DPP) and P5 (BDT‐BTDQ) were designed... 
power conversion efficiency | polymer solar cells | random terpolymer | benzothiadiazolequinoxaline | BANDGAP | DESIGN | POLYMER SCIENCE | COPOLYMERS
Journal Article
16.