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animals (116) 116
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Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7
Gq[alpha] signaling has been implicated in cardiac hypertrophy. In addition, angiotensin II (Ang II) was also shown to induce its hypertrophic effect through... 
Hypertension | Complications and side effects | Heart enlargement | Physiological aspects | Muscle cells | Development and progression | Genetic aspects | Research
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2019, Volume 97, Issue 9, pp. 872 - 879
Resveratrol (RV), a polyphenolic component of red wine, has been shown to attenuate high blood pressure (BP) in spontaneously hypertensive rats (SHRs). We... 
Giα proteins | blood pressure | cellules musculaires lisses vasculaires | protéines Giα | tension artérielle | VSMC | SHR | rat SHR | resveratrol
Journal Article
American Journal of Physiology, ISSN 0363-6135, 03/2016, Volume 310, Issue 5, p. H608
  We showed previously that vascular smooth muscle cells (VSMCs) from spontaneously hypertensive rats (SHRs) exhibit overexpression of Gqa/PLCβ1 proteins,... 
Oxidative stress | Signal transduction | Cell growth | Protein synthesis | Rodents | Protein expression | T cell receptors | Kinases
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2017, Volume 95, Issue 8, pp. 945 - 953
We previously showed that augmented levels of endogenous angiotensin II (AngII) contribute to vascular smooth muscle cell (VSMC) hypertrophy through the... 
c-Src | récepteur de facteurs de croissance | angiotensin II | resvératrol | growth factor receptor | angiotensine II | resveratrol | oxidative stress | stress oxydatif
Journal Article
American Journal of Physiology, ISSN 0363-6143, 07/2014, Volume 307, Issue 1, p. C97
  Vascular ... signaling has been shown to contribute to cardiac hypertrophy. In addition, angiotensin II (ANG II) was shown to induce vascular smooth muscle... 
Proteins | Phosphorylation | Protein synthesis | Rodents | Smooth muscle | ACE inhibitors
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2012, Volume 302, Issue 8, pp. H1591 - H1602
Journal Article
Journal Article
Physiological Reports, 03/2018, Volume 6, Issue 6, pp. e13658 - n/a
We earlier showed that vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) exhibit enhanced expression of Giα proteins which was... 
Giα proteins | cGMP | SHR | oxidative stress | Hypertension | Peroxynitrite | Hydrogen peroxide | Intracellular levels | Body weight | Smooth muscle | Superoxide | NAD(P)H oxidase | Proteins | Sodium nitroprusside | Molecular modelling | Sodium | Cyclic GMP | Rodents | Nitric oxide | Blood pressure | Intracellular
Journal Article
Pharmacology Research & Perspectives, ISSN 2052-1707, 02/2018, Volume 6, Issue 1, pp. e00375 - n/a
Hypertension is associated with vascular remodeling due to hyperproliferation and hypertrophy of vascular smooth muscle cells (VSMC). Recently, we showed the... 
Gqα/PLCβ proteins | VSMC | SHR | hypertrophy | NPR‐C | NPR-C
Journal Article
American Journal of Physiology, ISSN 0363-6143, 06/2013, Volume 304, Issue 12, p. C1198
  We previously showed that angiotensin II (ANG II)-induced overexpression of inhibitory G proteins (G...) was attenuated by dibutyryl-cAMP (db-cAMP) in A10... 
Proteins | Hypertension | Cell growth | Phosphorylation | Gene expression | Kinases
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0179301
Vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) exhibit decreased levels of nitric oxide (NO) that may be responsible for the... 
Cyclic GMP - pharmacology | Reactive Oxygen Species - metabolism | Nitric Oxide - pharmacology | NADPH Oxidases - metabolism | Rats, Inbred WKY | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Nitroprusside - pharmacology | Protein Carbonylation - drug effects | Cyclic GMP - analogs & derivatives | Oxadiazoles - pharmacology | Superoxides - metabolism | src-Family Kinases - metabolism | DNA - biosynthesis | Flavonoids - pharmacology | Nitric Oxide Donors - pharmacology | Phosphorylation - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Rats, Inbred SHR | Myocytes, Smooth Muscle - enzymology | Thiobarbituric Acid Reactive Substances - metabolism | Muscle, Smooth, Vascular - cytology | Animals | Signal Transduction - drug effects | Receptor, Angiotensin, Type 1 - metabolism | Cell Proliferation - drug effects | Oxidative Stress - drug effects | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | S-Nitroso-N-Acetylpenicillamine - pharmacology | Oxidative stress | Phosphorylation | Platelet-derived growth factor | Pathogenesis | Oxidase | Antibodies | Smooth muscle | Kinases | NAD(P)H oxidase | Western blotting | Proteins | Signal transduction | Receptors | NOX4 protein | Epidermal growth factor | Pathways | Rodents | Cyclic GMP | Cell cycle | Attenuation | Physiology | Growth factors | Carbonyls | Hypertension | Intracellular levels | Extracellular signal-regulated kinase | Rats | MAP kinase | Superoxide | Pharmacology | Growth factor receptors | Src protein | NAD | Inhibitors | Nitric oxide
Journal Article
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