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STEM CELLS, ISSN 1066-5099, 01/2017, Volume 35, Issue 1, pp. 158 - 169
Human patient‐derived induced pluripotent stem cells (hiPSCs) provide unique opportunities for disease modeling and drug development. However, adapting hiPSCs... 
High throughput | FMRP | Induced pluripotent stem cells | FMR1 | Luciferase | Fragile X syndrome | Drug discovery | IDENTIFY COMPOUNDS | KNOCKOUT MICE | DNA DEMETHYLATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | FULL MUTATION | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN EXPRESSION | MOUSE MODEL | HUMAN FIBROBLASTS | HISTONE MODIFICATIONS | HEMATOLOGY | Cell Line | Small Molecule Libraries - pharmacology | Luciferases - metabolism | Pluripotent Stem Cells - cytology | Nanoparticles - chemistry | Humans | Transcriptional Activation - drug effects | Neural Stem Cells - drug effects | Neurons - cytology | Fragile X Mental Retardation Protein - metabolism | Neural Stem Cells - cytology | Pluripotent Stem Cells - metabolism | Azacitidine - pharmacology | Cell Differentiation - genetics | Cell Differentiation - drug effects | Pluripotent Stem Cells - drug effects | Fragile X Mental Retardation Protein - genetics | Neurons - metabolism | Neurons - drug effects | Neural Stem Cells - metabolism | Genes, Reporter | Autism | Analysis | Genes | Genomics | Journalists | Stem cells | Development and progression | Genetic engineering | Gene expression | Mental illness | CRISPR | High-throughput screening | Activation | Genomes | Drug screening | Drug development | Mental retardation | Progenitor cells | Gene silencing | Organic chemistry | Screening | Fragile X mental retardation protein | Cells (biology) | Phenotyping | Neural stem cells | Modelling | Pluripotency | Index Medicus | drug discovery | luciferase | induced pluripotent stem cells | high throughput
Journal Article
Organic Letters, ISSN 1523-7060, 09/2018, Volume 20, Issue 18, pp. 5529 - 5532
Screening of a marine natural products library for inhibitors of TGF/beta revealed five pyrimidinedione derivatives, biemamides A-E (1-5). The structures were... 
FIBROSIS | CELLS | CIRCULAR-DICHROISM | NATURAL-PRODUCTS | CONFIGURATION | CHEMISTRY, ORGANIC | RECEPTORS | CANCER | TRANSDIFFERENTIATION | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e89349 - e89349
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 516 - 11
Journal Article
PLoS computational biology, ISSN 1553-734X, 08/2019, Volume 15, Issue 8, pp. e1006813 - e1006813
Prediction of compounds that are active against a desired biological target is a common step in drug discovery efforts. Virtual screening methods seek some... 
Index Medicus
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 01/2019, Volume 59, Issue 1, pp. 282 - 293
Virtual (computational) high-throughput screening provides a strategy for prioritizing compounds for experimental screens, but the choice of virtual screening... 
ACCURATE | CHEMISTRY, MEDICINAL | DOCKING | DRUG DISCOVERY | ALGORITHM | METRICS | COMPUTER SCIENCE, INFORMATION SYSTEMS | CHEMISTRY, MULTIDISCIPLINARY | DNA-REPLICATION | PREDICTION | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | GENERATION | PAINS | Proteins | Screening | Algorithms | Neural networks | Machine learning | Docking | Strategy | Workflow | Screens
Journal Article
Biologia Plantarum, ISSN 0006-3134, 6/2011, Volume 55, Issue 2, pp. 269 - 278
Journal Article
01/2008, ISBN 054962970X
The completion of the human genome project has ushered in the genomics age. Genomic science can be characterized by the creation and analysis of large datasets... 
Molecular biology | Genetics | Bioinformatics
Dissertation
Nature Biomedical Engineering, ISSN 2157-846X, 06/2017, Volume 1, Issue 7
The physiological relevance of Matrigel as a cell-culture substrate and in angiogenesis assays is often called into question. Here, we describe an array-based... 
MORPHOGENESIS | IN-VITRO | HYDROGELS | RECEPTOR TYROSINE KINASES | INHIBITION | ANGIOGENESIS | ENGINEERING, BIOMEDICAL | ENDOTHELIAL-CELLS | DIFFERENTIATION | TUMOR-GROWTH | BASEMENT-MEMBRANE MATRICES
Journal Article
POLISH JOURNAL OF PATHOLOGY, ISSN 1233-9687, 2017, Volume 68, Issue 3, pp. 234 - 240
The aim of this study was to examine the expression of TGF-beta 1 and TGF-beta receptor type II (RII) and the impact of the -509C > T single nucleotide... 
POPULATION | CELLS | 509C > T SNP | METASTASIS | gastric cancer | TGF-beta 1 | RISK | PATHOLOGY | ASSOCIATION | BETA | TGF-BETA-1
Journal Article
Genome, ISSN 0831-2796, 1991, Volume 34, Issue 6, pp. 1028 - 1031
Nontranscribed spacers of plant genes coding for ribosomal 5S RNA were amplified using the polymerase chain reaction. Primers were synthesized that were... 
CHROMOSOME | POLYMERASE CHAIN REACTION | RNA GENES | SEQUENCES | DNA POLYMORPHISM | BARLEY | GENETICS & HEREDITY | PLANTS | 5S GENES | WHEAT
Journal Article
01/2008, ISBN 054962970X, Volume 69, Issue 5
The completion of the human genome project has ushered in the genomics age. Genomic science can be characterized by the creation and analysis of large datasets... 
Book Chapter
Thesis (Ph.D.)-- University of Wisconsin--Madison, 2008. Includes bibliographical references (p. 153-155). Also available on the Internet. 
Dissertation
Thesis (Ph.D.)-- University of Wisconsin--Madison, 2008. Includes bibliographical references (p. 153-155). 
Dissertation
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