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Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2110 - 16
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 04/2017, Volume 77, Issue 7, pp. 1741 - 1752
Glioma-initiating cells (GIC) are considered the underlying cause of recurrences of aggressive glioblastomas, replenishing the tumor population and undermining... 
Oncology | Cancer Research | INHIBITION | ONCOLOGY | HUMAN GLIOBLASTOMA | HIGH-THROUGHPUT | GENE-EXPRESSION | T-TYPE | MULTIDRUG-RESISTANCE | IDENTIFICATION | CULTURE | TUMOR-INITIATING CELLS | CANCER STEM-CELLS | Unfolded Protein Response - drug effects | Calcium Channels, T-Type - physiology | Humans | Brain Neoplasms - pathology | Sodium - metabolism | Brain Neoplasms - drug therapy | Calcium Channel Blockers - pharmacology | Brain Neoplasms - metabolism | Glioma - metabolism | Amino Acids - metabolism | Animals | Biological Transport | Glioma - pathology | Cell Death | Proteomics | Cell Line, Tumor | Dihydropyridines - pharmacology | Neoplastic Stem Cells - pathology | Mice | Potassium Channels, Calcium-Activated - antagonists & inhibitors | Mycotoxins - pharmacology | Glioma - drug therapy | Drugs | Brain tumors | Glioblastoma | Bioelectricity | Amino acids | Drug development | Channels | Potassium channels (calcium-gated) | Depolarization | Protein folding | Glioma cells | Nutrients | Membrane potential | Protein transport | Calcium channels | Starvation | Integrated approach | Nutrient transport | Cell survival | Mortality | Calcium channels (voltage-gated) | Calcium channels (T-type) | Signaling | Chemotherapy | Acids | Cell death | Transport | Apoptosis | Life Sciences | Cellular Biology | Cancer | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
Nature, ISSN 0028-0836, 01/2008, Volume 451, Issue 7177, pp. 460 - 464
Stem cell self-renewal implies proliferation under continued maintenance of multipotency. Small changes in numbers of stem cells may lead to large differences... 
Cell proliferation | Histones | Physiological aspects | Research | Neurotransmitter receptors | Neurotransmitters | Cellular biology | DNA damage | Stem cells | Cell cycle
Journal Article
SpringerPlus, ISSN 2193-1801, 12/2016, Volume 5, Issue 1, pp. 1 - 10
Pluripotent stem cells are the starting cell type of choice for the development of many cell-based regenerative therapies due to their rapid and unlimited... 
Cell cycle | Science | ZD7288 | Serum | Proliferation | Embryonic stem cells | Differentiation | Ion channel modulator | Pluripotency | Science, general | TRANSPORTERS | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | STATE | PLURIPOTENT CELLS | OCT4 | PHASE | NANOG | EXPRESSION | CYCLE
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2017, Volume 12, Issue 12, p. e0188772
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 10/2017, Volume 8, p. 726
Stem cells display a fundamentally different mechanism of proliferation control when compared to somatic cells. Uncovering these mechanisms would maximize the... 
PDD | Small molecules | Zebrafish | Phenotype | Mouse | Stem cells | phenotype | MOTOR-NEURONS | stem cells | PROTEIN | GROUND-STATE | DRUG DISCOVERY | SELF-RENEWAL | PLURIPOTENCY | OLIGODENDROCYTES | mouse | GROWTH | PHARMACOLOGY & PHARMACY | zebrafish | small molecules | CYCLE | Drug discovery
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e115698
Tumor-initiating cells are a subpopulation in aggressive cancers that exhibit traits shared with stem cells, including the ability to self-renew and... 
GLIOBLASTOMA | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | CHEMOTHERAPY | TUMOR-INITIATING CELLS | BRAIN-TUMORS | Oligonucleotide Array Sequence Analysis | Neoplastic Stem Cells - drug effects | Humans | Brain Neoplasms - pathology | Gene Expression Profiling | Glioma - genetics | Neoplastic Stem Cells - metabolism | Glioma - pathology | Neoplastic Stem Cells - pathology | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Calcium - pharmacology | RNA, Messenger - genetics | Neural Stem Cells - drug effects | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Neural Stem Cells - pathology | Blotting, Western | Signal Transduction - drug effects | Cell Differentiation - drug effects | Fluorescent Antibody Technique | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Neural Stem Cells - metabolism | Glioma - drug therapy | Drugs | Brain | Cell culture | Nestin | Calcium | Brain tumors | Brain cancer | Genes | Lipid-binding protein | Radiation | Homeostasis | Genomes | Biochemistry | Glutamic acid receptors | Cancer therapies | Calcium signalling | Thapsigargin | Immunology | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid | Glioma cells | Cell cycle | Calcium buffering | Physiology | Ion channels | Calcimycin | Calcium homeostasis | Sodium channels | Calcium channels | Sensitivity analysis | Dopamine | Functional analysis | Radiation therapy | Biophysics | Potassium channels | Gene expression | Pathology | Chemotherapy | Sensitivity | Sodium | Medical prognosis | Stem cells | Radiation tolerance | Neural stem cells | Potassium | Basic Medicine | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Cancer and Oncology | Klinisk medicin | Immunology in the medical area | Cancer och onkologi
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2013, Volume 110, Issue 16, pp. E1524 - E1532
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 45, pp. 73200 - 73215
Glioblastoma multiforme (GBM, astrocytoma grade IV) is the most common malignant primary brain tumor in adults. Addressing the shortage of effective treatment... 
Drug repurposing | Stilbenoids | Cancer therapeutics | Glioblastoma initiating cells | Glioblastoma | RESVERATROL | APOPTOSIS | stilbenoids | OXIDATIVE STRESS | STEM-CELLS | PROTEIN TXNIP | cancer therapeutics | GENOMIC ANALYSIS | CELL-CYCLE ARREST | CANCER | TEMOZOLOMIDE | CELL BIOLOGY | IN-VITRO | glioblastoma | drug repurposing | glioblastoma initiating cells | Stilbenes - therapeutic use | Humans | Middle Aged | Brain Neoplasms - pathology | Transcriptome | Male | Gene Expression Profiling | Stilbenes - pharmacology | DNA Copy Number Variations | Gene Knockdown Techniques | Aged, 80 and over | Female | Antineoplastic Agents, Phytogenic - therapeutic use | Brain Neoplasms - drug therapy | Drug Synergism | Phenotype | MAP Kinase Signaling System - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Glioblastoma - pathology | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Mutation | Antineoplastic Agents, Phytogenic - pharmacology | Cell Cycle - drug effects | Glioblastoma - drug therapy | Quinazolines - pharmacology | Biological Sciences | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell and Molecular Biology | Cell Biology | Naturvetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences | Cellbiologi | Cell- och molekylärbiologi
Journal Article