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Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11127 - 11143
Selective immunoproteasome inhibition is a promising approach for treating autoimmune disorders, but optimal proteolytic active site subunit inhibition... 
Journal Article
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 2014, Volume 33, Issue 1, pp. 111 - 111
Journal Article
Journal Article
Journal of visualized experiments : JoVE, ISSN 1940-087X, 2009, Issue 27
High Content Analysis (HCA) assays combine cells and detection reagents with automated imaging and powerful image analysis algorithms, allowing measurement of... 
Astrocytes - cytology | Astrocytes - drug effects | Animals | Rats | Neurons - cytology | Toxicity Tests - methods | Coculture Techniques - methods | Neurons - drug effects | Index Medicus
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 04/2017, Volume 8, Issue 4, pp. 413 - 417
Building upon the success of bortezomib (VELCADE) and carfilzomib (KYPROLIS), the design of a next generation of inhibitors targeting specific subunits within... 
LMP2 | β1c | immunoproteasome | constitutive proteasome | β1i | 20S PROTEASOME | CARFILZOMIB | DESIGN | CHEMISTRY, MEDICINAL | beta 1i | PHARMACOKINETICS | METABOLISM | beta lc
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 1022 - 1022
Journal Article
NEUROSCIENCE RESEARCH, ISSN 0168-0102, 2010, Volume 68, pp. E128 - E128
Conference Proceeding
oncology, ISSN 2162-3619, 2013, Volume 2, Issue 1, pp. 2 - 2
In clinical and experimental settings, antibody-based anti-CD20/rituximab and small molecule proteasome inhibitor (PI) bortezomib (BTZ) treatment proved... 
Viral antibodies | Parenting | Bortezomib | RNA | Antibodies | Biological products industry | B cells | Comparative analysis | Drug resistance | Resistance | Anti-CD20/rituximab therapy | Autoimmune disorders | Proteasome inhibitors
Journal Article
Journal Article
HUMAN MUTATION, ISSN 1059-7794, 08/2013, Volume 34, Issue 8, pp. 1085 - 1093
Cystathionine beta-synthase (CBS) deficiency is an inborn error of metabolism characterized by extremely elevated levels of plasma total homocysteine. The vast... 
aminoaciduria | SINGLE-AGENT CARFILZOMIB | SEVERE HYPERHOMOCYSTEINEMIA | MULTIPLE-MYELOMA | HOMOCYSTEINE | PROTEIN | inborn error | NATURAL-HISTORY | missense mutation | chaperone | MUTATION | DISEASE | GENETICS & HEREDITY | BETA-SYNTHASE | HOMOCYSTINURIA | genetic disease | Heat shock proteins | Physiological aspects | Analysis | Homocysteine | Mutation
Journal Article
Journal of Hematology and Oncology, ISSN 1756-8722, 01/2014, Volume 7, Issue 1, pp. 7 - 7
Journal Article
Journal of Hematology & Oncology, ISSN 1756-8722, 01/2014, Volume 7, Issue 1, pp. 7 - 7
Despite encouraging results with the proteasome inhibitor bortezomib in the treatment of hematologic malignancies, emergence of resistance can limit its... 
Studies | Medical research | Cytokines | Blood diseases | Acquisitions & mergers
Journal Article
by Frankenfeld, John W and Schulz, Wolfgang and McMurty, George J and Petersen, Gary W and May, G. A and Hering, F. S and Schwartz, J. I and Heywood, J. B and Chigier, N. A and Grohse, E. W and Walker, J. D and Colwell, R. R and Petrakis, L and Pergament, H. S and Thorpe, R. D and Schoepf, Richard W and Krzyczkowski, Roman and Henneman, Suzanne S and Hudson, Charles L and Putnam, Evelyn S and Thiesen, Donna J and Parks, G. A and McCarty, Perry L and Leckie, J. O and Schrumpf, Barry J and Simonson, G. H and Paine, D. P and Lawrence, R. D and Pyott, W. T and Leh, M and Elders, W and Combs, J and Caplen, T and Harrison, F. L and Wong, K. M and Heft, R. E and Charnell, Robert L and Lehmann, Edward J and Mallon, Lawrence G and Hatfield, Cecile and Adams, Gerald H and Johanning, James and Talvitie, Antti and Noll, Kenneth E and Miller, Terry and Smiarowski, Joseph F and Willis, Cleve E and Foster, John H and Schlesinger, Benjamin and Daetz, Douglas and Lear, Donald U and Smith, Mona F and Hundemann, Audrey S and Crockett, Pernell W and Werner, Kirk G and Carroll, Thomas E and Maase, David L and Genco, Joseph E and Ifeadi, Christopher N and Lowman, F. G and Christensen, S. W and Van Winkle, W and Mattice, J. S and Harrison, Elizabeth A and Barker, James C and Chesness, Jerry L and Smith, Ralph E and Shaheeen, Donald G and Raney, R. Keith and Borton, T and Wezernak, C. T and Raney, R. K and Sherwani, Jabbor K and Moreau, David H and Eisenberg, Norman A and Lynch, Cornelius J and Breeding, Roger J and Johnson, J. D and Foster, K. E and Mouat, D. A and Clark, R and Hyden, John William and Owen, Wilfred and Bayfield, Neil G and Barrow, Graham C and Stolz, Stephanie B and Wienckowski, Louis A and Brown, Betram S and Keyfitz, Nathan and Wilson, W. L and Newman, Peter W. G and Bammi, Deepak and Bammi, Dalip and Goddard, James E and Chisholm, Tony and Walsh, Cliff and Brennan, Geoffrey and Thompson, K. S and Richardson, R and Jensen, Clayton E and ... and Office of Technology Assessment and Office of Science and Technology
Environmental Management, ISSN 0364-152X, 01/1977, Volume 1, Issue 1, pp. 67 - 96
Journal Article
2012, Volume 32, Issue 5
Fluorescently labeled gelatin has been an informative tool in the study of cell invasion and matrix degradation. The method involves plating cells on a culture... 
Magazine Article
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