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1. Full Text MicroRNAs in metabolism and metabolic disorders
by Rottiers, Veerle and Näär, Anders M
Nature reviews. Molecular cell biology, ISSN 1471-0072, 04/2012, Volume 13, Issue 4, pp. 239 - 250
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fatty Liver - genetics | Fatty Liver - metabolism | Signal Transduction | Humans | Homeostasis | Lipid Metabolism | Metabolic Syndrome - metabolism | MicroRNAs - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Oligoribonucleotides, Antisense - pharmacology | Cholesterol - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Obesity - genetics | Obesity - metabolism | Insulin - metabolism | Metabolic Diseases - metabolism | Metabolic Syndrome - genetics | Endocrine System - metabolism | Non-alcoholic Fatty Liver Disease | Glucose - metabolism | Metabolic Diseases - genetics | MicroRNAs - genetics | MicroRNA | Physiological aspects | Metabolic diseases | Genetic aspects | Research | Lipid metabolism | Genetic regulation | Metabolism | Risk factors | Index Medicus
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2. Full Text SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling
by Toiber, Debra and Erdel, Fabian and Bouazoune, Karim and Silberman, Dafne M and Zhong, Lei and Mulligan, Peter and Sebastian, Carlos and Cosentino, Claudia and Martinez-Pastor, Barbara and Giacosa, Sofia and D’Urso, Agustina and Näär, Anders M and Kingston, Robert and Rippe, Karsten and Mostoslavsky, Raul
Molecular cell, ISSN 1097-2765, 08/2013, Volume 51, Issue 4, pp. 454 - 468
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genomic Instability | Immunoprecipitation | Humans | DNA Repair - genetics | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Chromatin Immunoprecipitation | DNA Damage - genetics | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Sirtuins - genetics | Chromosomal Proteins, Non-Histone - metabolism | Cells, Cultured | Sirtuins - physiology | Adenosine Triphosphatases - metabolism | Chromatin Assembly and Disassembly | Nucleosomes - metabolism | Hippocampus - cytology | Chromosomal Proteins, Non-Histone - genetics | Mice, Knockout | Hippocampus - metabolism | Animals | Adenosine Triphosphatases - genetics | Mice | Histones - metabolism | Chromatin - genetics | Sirtuins - metabolism | Genetic research | Chromatin | DNA damage | Genomics | DNA | Cells | Index Medicus
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3. Full Text SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait
by Wu, Su and Näär, Anders M
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 10369 - 17
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell survival | Therapeutic applications | Gene regulation | Melanoma | Cytotoxicity | Antisense oligonucleotides | RNA polymerase | Gene expression | Fatty acids | DNA-directed RNA polymerase | Skin cancer | Metastases | Signal transduction | Medical prognosis | Index Medicus
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4. Full Text MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
by S. Hani Najafi-Shoushtari and Fjoralba Kristo and Yingxia Li and Toshi Shioda and David E. Cohen and Robert E. Gerszten and Anders M. Näär
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2010, Volume 328, Issue 5985, pp. 1566 - 1569
MicroRNA | Genes | HDL lipoproteins | REPORTS | Cell lines | Stem cells | Journalism | Gene expression regulation | Mice | Macrophages | Cholesterols | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Up-Regulation | Humans | Homeostasis | MicroRNAs - metabolism | Sterol Regulatory Element Binding Proteins - genetics | ATP-Binding Cassette Transporters - genetics | RNA Interference | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | 3' Untranslated Regions | ATP Binding Cassette Transporter 1 | Sterol Regulatory Element Binding Protein 1 - metabolism | Cell Line | Oligonucleotides, Antisense - pharmacology | Introns | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Sterol Regulatory Element Binding Proteins - metabolism | Cholesterol - metabolism | Macrophages - metabolism | Animals | Diet | Sterol Regulatory Element Binding Protein 1 - genetics | Cholesterol, HDL - blood | MicroRNAs - genetics | Physiological aspects | Genetic aspects | Binding proteins | Cholesterol | Biosynthesis | Cellular biology | Ribonucleic acid--RNA | Gene expression | Index Medicus
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5. Full Text A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans
by Walker, Amy K and Jacobs, René L and Watts, Jennifer L and Rottiers, Veerle and Jiang, Karen and Finnegan, Deirdre M and Shioda, Toshi and Hansen, Malene and Yang, Fajun and Niebergall, Lorissa J and Vance, Dennis E and Tzoneva, Monika and Hart, Anne C and Näär, Anders M
Cell (Cambridge), ISSN 0092-8674, 2011, Volume 147, Issue 4, pp. 840 - 852
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Caenorhabditis elegans - metabolism | Humans | Phosphatidylcholines - biosynthesis | Caenorhabditis elegans Proteins - metabolism | Endoplasmic Reticulum - metabolism | S-Adenosylmethionine - biosynthesis | Transcription Factors - metabolism | Animals | RNA Interference | Cell Line, Tumor | Models, Animal | Mice | Lipogenesis | Sterol Regulatory Element Binding Protein 1 - metabolism | Proteins | Caenorhabditis elegans | Synthesis | Genetic disorders | Genes | Insulin resistance | Phospholipids | Methylation | Fatty acids | S-adenosylmethionine | Cells | Obesity | Binding proteins | Carbon cycle (Biogeochemistry) | Protein binding | Index Medicus
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6. Full Text miR-33: A Metabolic Conundrum
by Näär, Anders M
Trends in endocrinology and metabolism, ISSN 1043-2760, 10/2018, Volume 29, Issue 10, pp. 667 - 668
microRNA | miR-33 | insulin resistance | obesity | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Obesity | Tissue Expansion | Animals | Adiposity | MicroRNAs | Insulin Resistance | Mice | Mice, Knockout | Insulin resistance | MicroRNA | Atherosclerosis | Index Medicus
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7. Full Text A SIRT1-LSD1 Corepressor Complex Regulates Notch Target Gene Expression and Development
by Mulligan, Peter and Yang, Fajun and Di Stefano, Luisa and Ji, Jun-Yuan and Ouyang, Jian and Nishikawa, Joy L and Toiber, Debra and Kulkarni, Madhura and Wang, Qun and Najafi-Shoushtari, S. Hani and Mostoslavsky, Raul and Gygi, Steven P and Gill, Grace and Dyson, Nicholas J and Näär, Anders M
Molecular cell, ISSN 1097-2765, 06/2011, Volume 42, Issue 5, pp. 689 - 699
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Sirtuin 1 - metabolism | Oxidoreductases, N-Demethylating - genetics | Immunoprecipitation | Receptors, Notch - metabolism | Epigenesis, Genetic | Oxidoreductases, N-Demethylating - physiology | Receptors, Notch - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Sirtuin 1 - genetics | Drosophila Proteins - physiology | Phenotype | Animals | Gene Expression Regulation, Developmental | Sirtuin 1 - physiology | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | Histones - metabolism | Mutation | Oxidoreductases, N-Demethylating - metabolism | Index Medicus
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8. Full Text Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction
by Nishikawa, Joy L and Boeszoermenyi, Andras and Vale-Silva, Luis A and Torelli, Riccardo and Posteraro, Brunella and Sohn, Yoo-Jin and Ji, Fei and Gelev, Vladimir and Sanglard, Dominique and Sanguinetti, Maurizio and Sadreyev, Ruslan I and Mukherjee, Goutam and Bhyravabhotla, Jayaram and Buhrlage, Sara J and Gray, Nathanael S and Wagner, Gerhard and Naar, Anders M and Arthanari, Haribabu
Nature (London), ISSN 0028-0836, 02/2016, Volume 530, Issue 7591, pp. 485 - 489
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fluconazole - pharmacology | Mediator Complex - metabolism | Transcriptional Activation - drug effects | Thiourea - pharmacology | Candidiasis - microbiology | Trans-Activators - chemistry | Ketoconazole - pharmacology | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Fungal - drug effects | Mediator Complex - chemistry | Drug Resistance, Multiple, Fungal - drug effects | Candidiasis - drug therapy | Protein Binding - drug effects | Nuclear Magnetic Resonance, Biomolecular | Binding Sites - drug effects | Antifungal Agents - pharmacology | Protein Structure, Tertiary | Hydrazines - pharmacology | Drug Resistance, Fungal - drug effects | Hydrazines - pharmacokinetics | Models, Molecular | Thiourea - pharmacokinetics | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Candida glabrata - metabolism | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Saccharomyces cerevisiae Proteins - metabolism | Trans-Activators - metabolism | Mice | Candida glabrata - genetics | Thiourea - analogs & derivatives | Candida glabrata - drug effects | Fungal Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Prevention | Drug resistance in microorganisms | Gene mutations | Yeast fungi | Physiological aspects | Genetic aspects | Research | Fungi | Transcription factors | Genes | Mutation | Fungal infections | RNA polymerase | Drug resistance | Urogenital system | Index Medicus
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