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Current issues in molecular biology, ISSN 1467-3037, 2018, Volume 25, pp. 99 - 132
Inflammasomes are multiprotein platforms assembled in the cytosol in response to pathogens and cell stress. Inflammasomes are recognized by their important... 
UNFOLDED PROTEIN RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MYCOBACTERIUM-TUBERCULOSIS INFECTION | INNATE IMMUNE-RESPONSE | TOLL-LIKE RECEPTORS | NF-KAPPA-B | APOPTOSIS IN-VIVO | FRANCISELLA-TULARENSIS | PYROPTOTIC CELL-DEATH | III SECRETION SYSTEM | LEGIONELLA-PNEUMOPHILA REPLICATION | Humans | Pyrin - genetics | Caspase 1 - immunology | Interleukin-1beta - genetics | Gram-Negative Bacteria - immunology | CARD Signaling Adaptor Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Calcium-Binding Proteins - immunology | Pyrin - immunology | Adaptor Proteins, Signal Transducing - immunology | Apoptosis Regulatory Proteins - genetics | Gram-Positive Bacteria - growth & development | Gram-Positive Bacteria - immunology | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | T-Lymphocytes - microbiology | DNA-Binding Proteins - immunology | Signal Transduction | Gene Expression Regulation | Interleukin-1beta - immunology | DNA-Binding Proteins - genetics | Immunity, Innate | Pyroptosis - genetics | Host-Pathogen Interactions | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Caspase 1 - genetics | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - genetics | Gram-Negative Bacteria - growth & development | T-Lymphocytes - immunology | Calcium-Binding Proteins - genetics | Pyroptosis - immunology
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 1/2018, Volume 200, Issue 2, pp. 768 - 774
Innate immune receptors have a key role in the sensing of malaria and initiating immune responses. As a consequence of infection, systemic inflammation emerges... 
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 01/2013, Volume 13, Issue 1, pp. 42 - 53
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 09/2019, Volume 106, Issue 3, pp. 631 - 640
The NLRP3 inflammasome is activated in response to multiple stimuli and triggers activation of caspase‐1 (CASP1), IL‐1β production, and inflammation. NLRP3... 
innate immunity | caspase‐1 | Leishmaniasis | MECHANISM | INTERLEUKIN-1-BETA | INNATE | IMMUNOLOGY | DECTIN-1 | CELL BIOLOGY | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | RESISTANCE | INFECTION | IL-1-BETA | HEMATOLOGY | caspase-1
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1, pp. e1003885 - e1003885
Cyclic paroxysm and high fever are hallmarks of malaria and are associated with high levels of pyrogenic cytokines, including IL-1. In this report, we describe... 
IMMUNE-RESPONSE | NECROSIS-FACTOR CACHECTIN | DENDRITIC CELLS | CHRONIC GRANULOMATOUS-DISEASE | MICROBIOLOGY | NALP3 INFLAMMASOME | PLASMODIUM-VIVAX MALARIA | DIFFERENTIAL REQUIREMENT | VIROLOGY | EXPERIMENTAL CEREBRAL MALARIA | TOLL-LIKE RECEPTORS | NF-KAPPA-B | PARASITOLOGY | Inflammation - pathology | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Intracellular Signaling Peptides and Proteins - immunology | Male | Monocytes - metabolism | Caspase 1 - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Monocytes - immunology | Interleukin-1beta - genetics | Shock, Septic - immunology | Malaria, Vivax - microbiology | Shock, Septic - metabolism | Plasmodium chabaudi - immunology | Bacterial Infections - genetics | Inflammation - metabolism | Bacterial Infections - immunology | Monocytes - pathology | Female | Intracellular Signaling Peptides and Proteins - genetics | Carrier Proteins - immunology | Malaria, Vivax - pathology | Shock, Septic - genetics | Shock, Septic - pathology | Plasmodium vivax - metabolism | Interleukin-1beta - immunology | Inflammation - immunology | Malaria, Vivax - metabolism | Plasmodium chabaudi - metabolism | Plasmodium vivax - immunology | Inflammasomes - genetics | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | Inflammasomes - immunology | Inflammation - genetics | Malaria, Vivax - immunology | Mice | Bacterial Infections - metabolism | Physiological aspects | Host-parasite relationships | Microbiological research | Inflammation | Research | Malaria | Index Medicus | Bacterial infections | Pathogenesis | Rodents | Deoxyribonucleic acid | DNA | Infections | Gene expression | Experiments | Patients | Viral infections | Fever
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 01/2019, Volume 26, Issue 2, pp. 429 - 437.e5
Activation of the NLRP3 inflammasome by parasites is critical for the outcome of leishmaniasis, a disease that affects millions of people worldwide. We... 
LPG | Leishmania | inflammasome | NLRP3 | macrophage | caspase-11 | non-canonical inflammasome | Leishmaniasis | lipophosphoglycan | caspase-1 | INNATE | IL-1-BETA | RECEPTORS | DECTIN-1 | CELL BIOLOGY
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1
  Cyclic paroxysm and high fever are hallmarks of malaria and are associated with high levels of pyrogenic cytokines, including IL-1β. In this report, we... 
Bacterial infections | Malaria | Pathogenesis | Rodents | Infections | Gene expression | Experiments | Patients | Viral infections | Fever | Deoxyribonucleic acid--DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36245
Journal Article
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