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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2018, Volume 38, Issue Suppl_1
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2018, Volume 38, Issue 12, pp. 2827 - 2842
OBJECTIVE—HDL (high-density lipoprotein) in plasma is a heterogeneous group of lipoproteins typically containing apo AI as the principal protein. Most HDLs... 
apolipoproteins | proteomics | enzyme-linked immunosorbent assay | lipoproteins, HDL | peptides | cardiovascular diseases | humans | OXIDATIVE STRESS | COMPLEMENT | PROTEIN | CLUSTERIN | HDL | A-II | METABOLISM | HIGH-RISK | CHOLESTEROL EFFLUX | PERIPHERAL VASCULAR DISEASE | PLATELET ACTIVATION | ALTERS | HEMATOLOGY | lipoproteins | CVD | Diagnostic tools | LDL | VLDL | Proteomics | HDL function | Antibodies | Risk prediction | HDL characterization | HDL proteome
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2019, Volume 39, Issue 11, pp. 2411 - 2430
OBJECTIVE:Clinical evidence has linked low HDL (high-density lipoprotein) cholesterol levels with high cardiovascular disease risk; however, its significance... 
apolipoprotein | high-density lipoprotein | TRIGLYCERIDE-RICH LIPOPROTEINS | PRE-BETA-HDL | RISK | IDENTIFICATION | carbohydrate | proteome | REPLACEMENT | monounsaturated fat | PLASMA | CHOLESTEROL LEVELS | ESTROGEN | PERIPHERAL VASCULAR DISEASE | metabolism | diet | CORONARY-HEART-DISEASE | HEMATOLOGY | APOLIPOPROTEIN-A-I
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2018, Volume 38, Issue Suppl_1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 30, pp. 9394 - 9399
Journal Article
Proteomics, ISSN 1615-9853, 01/2017, Volume 17, Issue 1-2, p. 1770014
  DOI: 10.1002/pmic.201600085 Metabolism studies traditionally use D3-Leu tracer for endogenous labeling of circulating proteins such as those on lipoproteins... 
Tracers (Biology) | Apolipoproteins | Metabolism | Automation | Lipoproteins
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 07/2015, Volume 112, Issue 30, p. 9394
IL-21 is a type I cytokine essential for immune cell differentiation and function. Although IL-21 can activate several STAT family transcription factors,... 
Transcription factors | Interleukins | T cells | Health aspects
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2015, Volume 112, Issue 30, p. 9394
  IL-21 is a type I cytokine essential for immune cell differentiation and function. Although IL-21 can activate several STAT family transcription factors,... 
Phosphorylation | Cytokines | T cell receptors | Gene expression | Cells
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 07/2015, Volume 112, Issue 30, pp. 9394 - 9394
IL-21 is a type I cytokine essential for immune cell differentiation and function. Although IL-21 can activate several STAT family transcription factors,... 
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, p. 307
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
B cells
Journal Article
Nature Communications, 08/2015, Volume 6, p. 7988
The canonical pathway for IL-1β production requires TLR-mediated NF-κB-dependent Il1b gene induction, followed by caspase-containing inflammasome-mediated... 
NF-κB protein | Dendritic cells | Serine | Stat3 protein | Caspase | Viruses | Lymphocytes T | IL-1β | Caspase-1 | CD4 antigen | Caspase-8 | Lymphocytes | Interleukin 1 | Interleukin 21 | Serine proteinase
Journal Article
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