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1. Full Text Ligand occupancy in crystal structure of [beta]1-adrenergic G protein-coupled receptor
by Andrew G W Leslie and Tony Warne and Christopher G Tate
Nature Structural & Molecular Biology, ISSN 1545-9993, 12/2015, Volume 22, Issue 12, p. 941
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2. Full Text Disorders of sex development: Insights from targeted gene sequencing of a large international patient cohort
by Eggers, Stefanie and Sadedin, S and van den Bergen, J.A and Robevska, G and Ohnesorg, T and Hewitt, Joanne and Lambeth, L and Bouty, A and Knarston, I.M and Tan, T.Y and Cameron, Fergus and Werther, G and Hutson, J and O'Connell, M and Grover, S.R and Heloury, Y and Zacharin, Margaret and Bergman, P and Kimber, C and Brown, J and Webb, N and Hunter, M.F and Shubha Srinivasan and Titmuss, A and Verge, C.F and Mowat, David and Smith, G and Smith, J and Ewans, L and Shalhoub, C and Crock, P and Cowell, C and Leong, G.M and Ono, M and Lafferty, A.R and Huynh, T and Visser, U and Choong, C.S and McKenzie, F and Pachter, N and Thompson, Elizabeth M and Couper, J and Baxendale, A and Gecz, Jozef and Wheeler, B.J and Jefferies, C and MacKenzie, K and Hofman, P and Carter, P and King, R.I and Krausz, Csilla and Ravenswaaij-Arts, Conny and Looijenga, Leendert and p, S and Riedl, S and Cools, Martine and Dawson, A and Juniarto, Achmad and Khadilkar, V and Khadilkar, A and Bhatia, V and Dũng, V.C and Atta, I and Raza, J and thi Diem Chi, N and Hao, T.K and Harley, Vincent and Koopman, Peter and Warne, G and Faradz, Sultana and Oshlack, A and Ayers, K.L and Sinclair, Anew
Genome Biology, ISSN 1474-7596, 11/2016, Volume 17, Issue 1, p. 243
textabstractBackground: Disorders of sex development (DSD) are congenital conditions in which chromosomal, gonadal, or phenotypic sex is atypical. Clinical... 
Testis | Variant | Massively parallel sequencing | MPS | Cohort | Gonad | Disorders of sex development | Mutation | Ovaries | Ovotestes | Genetic diagnosis | Targeted gene panel | DIAGNOSIS | ANDROGEN-RECEPTOR GENE | REPEAT LENGTH | GONADOTROPIN-RELEASING-HORMONE | DESERT-HEDGEHOG GENE | IDENTIFICATION | HUMAN TESTIS DETERMINATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GONADAL-DYSGENESIS | MUTATIONS | HYPOSPADIAS | Disorders of Sex Development - diagnosis | Genetic Predisposition to Disease | Ovary - pathology | Genetic Association Studies | Humans | Gonads - pathology | Male | Disorders of Sex Development - genetics | Mutation - genetics | Testis - growth & development | Ovary - growth & development | Genetic Variation | Phenotype | Testis - pathology | Disorders of Sex Development - pathology | Pedigree | Gonads - growth & development | Chromosome Aberrations | Female | High-Throughput Nucleotide Sequencing | Cohort Studies | Performance evaluation | Congenital diseases | Genes | Sex | Families & family life | Genomes | Patients | Genetic screening | Genetic counseling | Etiology | Infertility | Diagnosis | Deoxyribonucleic acid--DNA
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3. Full Text Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis
by White, Stefan and Ohnesorg, Thomas and Notini, Amanda and Roeszler, Kelly and Hewitt, Jacqueline and Daggag, Hinda and Smith, Craig and Turbitt, Erin and Gustin, Sonja and van den Bergen, Jocelyn and Miles, Denise and Western, Patrick and Arboleda, Valerie and Schumacher, Valerie and Gordon, Lavinia and Bell, Katrina and Bengtsson, Henrik and Speed, Terry and Hutson, John and Warne, Garry and Harley, Vincent and Koopman, Peter and Vilain, Eric and Sinclair, Andrew
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17793
Disorders of sex development (DSD), ranging in severity from mild genital abnormalities to complete sex reversal, represent a major concern for patients and... 
SRY-RELATED GENE | DEPENDENT PROBE AMPLIFICATION | TESTIS DETERMINATION | CAMPOMELIC DYSPLASIA | ARRAY-CGH | BIOLOGY | KB UPSTREAM | DETERMINATION REVEALS | TRANSLOCATION BREAKPOINTS | SOX9 | MUTATIONS | Chromosome Deletion | Gonads - embryology | Chromosomes, Human, Pair 8 - genetics | Calcium-Calmodulin-Dependent Protein Kinase Type 1 - genetics | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Regulation | GATA4 Transcription Factor - genetics | Male | DNA Copy Number Variations - genetics | Chromosomes, Human, Pair 17 - genetics | Gonads - metabolism | Algorithms | Animals | Gonadal Dysgenesis, 46,XY - genetics | Chromosome Aberrations | Female | Calcium-Calmodulin-Dependent Protein Kinase Type 1 - metabolism | Mice | Gene Rearrangement - genetics | SOX9 Transcription Factor - genetics | Genes | Analysis | Genomics | Transcription factors | Copy number | Gene regulation | Sox9 protein | Disorders | Sex | Genomes | Single-nucleotide polymorphism | Gene sequencing | Genotype & phenotype | Pathways | Clonal deletion | Cooperation | Deletion | Licensed products | Chromosomes | Dysplasia | Sex reversal | Abnormalities | Functional analysis | Gene expression | Patients | Children & youth | Genetic programs | Gonadal dysgenesis | Enhancers | Hospitals | Gene duplication | Diabetes | Mutation | Disruption | Binding sites
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4. Full Text Worldwide Initiation of Holocene Marine Deltas by Deceleration of Sea-Level Rise
by Daniel Jean Stanley and Andrew G. Warne
Science, ISSN 0036-8075, 7/1994, Volume 265, Issue 5169, pp. 228 - 231
Radiocarbon-dated deltaic sequences of Holocene age from different parts of the world began to accumulate within a restricted time range, from about 8500 to... 
Tropical regions | Climate change | Radiocarbon dating | Paleoclimatology | Isostasy | Sea level rise | Reports | Sediments | Sea level | Acceleration | Tectonics | NORTHERN AUSTRALIA | MARGIN | RATES | SUBSIDENCE | EGYPT | CHINA | MULTIDISCIPLINARY SCIENCES | SHELF | NILE-DELTA | RIVER DELTA | Deltas | Research | Paleogeography | Holocene
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5. Full Text Functional characterization of novelNR5A1variants reveals multiple complex roles in disorders of sex development
by Robevska, G and van den Bergen, JA and Ohnesorg, T and Eggers, S and Hanna, C and Hersmus, R and Thompson, EM and Baxendale, A and Verge, CF and Lafferty, AR and Marzuki, NS and Santosa, A and Listyasari, NA and Riedl, S and Warne, G and Looijenga, L and Faradz, S and Ayers, KL and Sinclair, AH
HUMAN MUTATION, ISSN 1059-7794, 01/2018, Volume 39, Issue 1, pp. 124 - 139
Variants in the NR5A1 gene encoding SF1have been described in a diverse spectrum of disorders of sex development (DSD). Recently, we reported the use of a... 
variable expressivity | PROTEIN-STRUCTURE | genotype-phenotype correlation | CRYPTORCHIDISM | VARIANT | STEROIDOGENIC FACTOR-I | oligogenic | NR5A1 | GLY146ALA POLYMORPHISM | mutation | FACTOR-1 | NR5A1 GENE | GENETICS & HEREDITY | 46,XY PATIENTS | disorders of sex development | PATIENT | MUTATIONS
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6. Full Text Functional characterisation of novel NR5A1 variants reveals multiple complex roles in Disorders of Sex Development
by Robevska, G and Den Bergen, J.A and Ohnesorg, T and Eggers, Stefanie and Hanna, C and Hersmus, Remko and Thompson, Elizabeth M and Baxendale, A and Verge, C.F and Lafferty, A.R and Marzuki, N.S and Santosa, A and Listyasari, N.A and Riedl, S and Warne, G and Looijenga, Leendert and Faradz, Sultana and Ayers, K.L and Sinclair, Anew
Human Mutation, ISSN 1059-7794, 01/2017
textabstractVariants in the NR5A1 gene encoding SF1 have been described in a diverse spectrum of disorders of sex development (DSD). Recently, we reported the... 
Variable expressivity | Genotype-phenotype correlation | Disorders of sex development | Mutation | Oligogenic | Nr5a1
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7. Full Text Nile Delta: Recent Geological Evolution and Human Impact
by Daniel Jean Stanley and Andrew G. Warne
Science, ISSN 0036-8075, 4/1993, Volume 260, Issue 5108, pp. 628 - 634
Few countries in the world are as dependent on water from a single source as Egypt. The natural Nile cycle of flow and sediment discharge has been disrupted by... 
Paleoclimatology | Sand | Coasts | Floodplains | Lagoons | Sediments | Sea level | River deltas | Mud | Alluvial plains | SEDIMENT TRANSPORT | RATES | SUBSIDENCE | COAST | DEPOSITS | LATE QUATERNARY | HEAVY MINERALS | EGYPT | MULTIDISCIPLINARY SCIENCES | PALEOCLIMATIC OSCILLATIONS | HOLOCENE SEQUENCES | Rivers | Research | Geology | Geological time | HUMAN POPULATIONS | CLIMATIC CHANGE | POPULATIONS | COASTAL REGIONS | LEVELS | NILE RIVER | EROSION | ENVIRONMENTAL IMPACTS | 540210 - Environment, Terrestrial- Basic Studies- (1990-) | ENVIRONMENTAL SCIENCES | MASS TRANSFER | RIVER DELTAS | SEA LEVEL | STREAMS | ENVIRONMENTAL TRANSPORT | RIVERS | SURFACE WATERS | GROUND SUBSIDENCE
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8. Full Text Erratum: Structure of the adenosine A 2A receptor bound to an engineered G protein
by Carpenter, Byron and Nehmé, Rony and Warne, Tony and Leslie, Andrew G W and Tate, Christopher G
Nature, 10/2016, Volume 538, Issue 7626, p. 542
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9. Full Text Late Quaternary Evolution of the Orinoco Delta, Venezuela
by Andrew G. Warne and Edgar H. Guevara and Andres Aslan
Journal of Coastal Research, ISSN 0749-0208, 4/2002, Volume 18, Issue 2, pp. 225 - 253
The modern Orinoco Delta is the latest of a series of stacked deltas that have infilled the Eastern Venezuelan Basin (EVB) since the Oligocene. During the late... 
Paleoclimatology | Coasts | Geology | Gulfs | Sediment yield | Sediments | Sea level | River deltas | Mud | Sediment transport | Late Pleistocene | Human impacts | Orinoco Delta | Subsidence | Late Quaternary | Venezuela | Guayana littoral current | Orinoco River | Paleoclimate | Guiana Coast | Sea-level change | Eastern Venezuela Basin | Holocene | sea-level change | late Pleistocene | FLUVIAL SYSTEMS | human impacts | paleoclimate | YANGTZE DELTA | GEOSCIENCES, MULTIDISCIPLINARY | subsidence | DEPOSITIONAL PATTERNS | MISSISSIPPI RIVER DELTA | NILE DELTA | SEA-LEVEL RISE | ENVIRONMENTAL SCIENCES | RHINE-MEUSE DELTA | GEOGRAPHY, PHYSICAL | SOUTH-AMERICA | late Quaternary | NORTHEASTERN COAST
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10. Full Text A long-term outcome study of intersex conditions
by Warne, Garry and Grover, Sonia and Hutson, John and Sinclair, Andrew and Metcalfe, Sylvia and Northam, Elisabeth and Freeman, Justin and Loughlin, Elizabeth and Rillstone, Mary and Anderson, Peter and Hughes, Eilis and Hooper, Juliette and Todd, Sheri and Zajac, Jeffrey D and Savulescu, Julian and MCRISSG and Murdoch Childrens Research Institute Sex Study Group
Journal of Pediatric Endocrinology and Metabolism, ISSN 0334-018X, 2005, Volume 18, Issue 6, pp. 555 - 567
Context: Clinical management of intersex conditions is controversial because the available evidence is limited and conflicting, with no longterm population... 
Intersex | Sexual satisfaction | Outcome | Quality of life | sexual satisfaction | 21-HYDROXYLASE DEFICIENCY | CONGENITAL ADRENAL-HYPERPLASIA | AMBIGUOUS GENITALIA | PSYCHOLOGICAL EVALUATION | IDENTITY | WOMEN | intersex | VAGINAL RECONSTRUCTION | ENDOCRINOLOGY & METABOLISM | PEDIATRICS | QUALITY-OF-LIFE | quality of life | SEXUALITY | outcome | FEMALE-PATIENTS | Sexual Behavior | Humans | Hirschsprung Disease - psychology | Male | Treatment Outcome | Diabetes Mellitus, Type 1 - therapy | Socioeconomic Factors | Gender Identity | Disorders of Sex Development - psychology | Family Relations | Social Behavior | Adolescent | Hirschsprung Disease - therapy | Quality of Life | Adult | Female | Surveys and Questionnaires | Marriage | Diabetes Mellitus, Type 1 - psychology | Disorders of Sex Development - therapy
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11. Full Text Ligand occupancy in crystal structure of β 1-adrenergic G protein coupled receptor
by Leslie, Andrew G.W and Warne, Tony and Tate, Christopher G
Nature Structural and Molecular Biology, ISSN 1545-9993, 12/2015, Volume 22, Issue 12, pp. 941 - 942
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12. Full Text Nile delta in its destruction phase
by Stanley, Daniel Jean and Warne, Andrew G
Journal of Coastal Research, ISSN 0749-0208, 06/1998, Volume 14, Issue 3, pp. 794 - 825
All deltas undergo alternating construction to destruction phases due to fundamental changes in the relative influence of sediment input from rivers and... 
River Nile | Aswan dams | Waterways | Canals | Egypt | Delta destruction | Drill cores | Lagoons | Lake Nasser | Coastal erosion | Diseases | Wetlands | Industrial waste | Pollution | Barrages | Delta construction | Land conversion | Salinization | Mediterranean Sea | Nile Cone | Population pressure | Nile delta | land conversion | HEAVY MINERALS | PALEOCLIMATIC OSCILLATIONS | pollution | delta construction | drill cores | wetlands | GEOSCIENCES, MULTIDISCIPLINARY | coastal erosion | RECENT SUBSIDENCE | LATE QUATERNARY STRATIGRAPHY | SEDIMENT DISPERSAL | canals | COAST | diseases | population pressure | SEA-LEVEL | HOLOCENE | industrial waste | salinization | waterways | lagoons | ENVIRONMENTAL SCIENCES | GEOGRAPHY, PHYSICAL | EVOLUTION | delta destruction | barrages
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13. Full Text CITED2 mutations potentially cause idiopathic premature ovarian failure
by Fonseca, Dora Janeth and Ojeda, Diego and Lakhal, Besma and Braham, Rim and Eggers, Stefanie and Turbitt, Erin and White, Stefan and Grover, Sonia and Warne, Garry and Zacharin, Margaret and Nevin Lam, Alexandra and Landolsi, Hanène and Elghezal, Hatem and Saâd, Ali and Restrepo, Carlos Martín and Fellous, Marc and Sinclair, Andrew and Koopman, Peter and Laissue, Paul
Translational Research, ISSN 1931-5244, 2012, Volume 160, Issue 5, pp. 384 - 388
Anomalies in gonadal development in a mouse knockout model of Cited2 have been recently described. In Cited2 −/− female gonads, an ectopic cell migration was... 
Internal Medicine | MEDICINE, RESEARCH & EXPERIMENTAL | SEX DETERMINATION | MEDICINE, GENERAL & INTERNAL | DEFECTS | FOXL2 | MEDICAL LABORATORY TECHNOLOGY | DNA Mutational Analysis | Humans | Middle Aged | Primary Ovarian Insufficiency - genetics | Trans-Activators - genetics | Repressor Proteins - genetics | Adult | Female | Mutation | Case-Control Studies | Genetic research | Cytogenetics | Genetic aspects | Analysis | Genes | Cells
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14. Full Text Ligand occupancy in crystal structure of [[beta].sub.1]-adrenergic G protein-coupled receptor
by Leslie, Andrew G.W and Warne, Tony and Tate, Christopher G
Nature Structural and Molecular Biology, ISSN 1545-9993, 12/2015, Volume 22, Issue 12, p. 941
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15. Full Text Holocene evolution of the western Orinoco Delta, Venezuela
by Aslan, Andres and White, William A and Warne, Andrew G and Guevara, Edgar H
Bulletin of the Geological Society of America, ISSN 0016-7606, 04/2003, Volume 115, Issue 4, pp. 479 - 498
The pristine nature of the Orinoco Delta of eastern Venezuela provides unique opportunities to study the geologic processes and environments of a major... 
Peat accumulation | Avulsion | Delta progradation | Holocene | Mudcapes | Orinoco delta | PEAT DEPOSITS | SYSTEM | avulsion | TRINIDAD | delta progradation | BARRIER | FLOODPLAIN | GEOSCIENCES, MULTIDISCIPLINARY | SEDIMENT | COAL BEDS | mudcapes | MUD VOLCANOS | peat accumulation | RIVER DELTA | HISTORY | Deltas | Natural history
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16. Full Text Structure of the adenosine A(2A) receptor bound to an engineered G protein
by Carpenter, B and Nehme, R and Warne, T and Leslie, AGW and Tate, CG
NATURE, ISSN 0028-0836, 08/2016, Volume 536, Issue 7614, pp. 104 - 104
G-protein-coupled receptors (GPCRs) are essential components of the signalling network throughout the body. To understand the molecular mechanism of... 
ADRENOCEPTOR | ACTIVATION | COMPLEX | CRYSTAL-STRUCTURE | GPCRS | MULTIDISCIPLINARY SCIENCES | COUPLED RECEPTORS | BINDING | AGONIST | INSIGHTS | Amino Acid Sequence | Humans | Crystallization | Models, Molecular | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Cytoplasm - metabolism | Heterotrimeric GTP-Binding Proteins - metabolism | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2A - metabolism | Receptors, Adrenergic, beta-2 - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Heterotrimeric GTP-Binding Proteins - chemistry | Receptor, Adenosine A2A - chemistry | Ligands | Protein Conformation | Binding Sites | Adenosine | G proteins | Analysis | Protein binding
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17. Full Text Geoarchaeological Interpretation of the Canopic, Largest of the Relict Nile Delta Distributaries, Egypt
by Jean-Daniel Stanley and Andrew G. Warne and Gerard Schnepp
Journal of Coastal Research, ISSN 0749-0208, 2004, Volume 20, Issue 3, pp. 920 - 930
Abstract The Canopic branch, the largest relict Nile distributary, once flowed across the NW Nile delta of Egypt to the Mediterranean. This study focuses on... 
avulsion | Canopic promontory | substrate failure | Herakleion | navigation | channel migration | sea-level rise | archaeology | subsidence | trade centers | Abu Qir Bay | Eastern Canopus | Nile floods | Shorelines | Coasts | Geology | Promontories | Bays | Canals | Sea level rise | Sediments | Sea level | River deltas | Navigation | Substrate failure | Subsidence | Archaeology | Channel migration | Avulsion | Sea-level rise | Trade centers | BRANCH | COAST | MOUTH | canopic promontory | POSITION | ENVIRONMENTAL SCIENCES | ROSETTA | GEOGRAPHY, PHYSICAL | GEOSCIENCES, MULTIDISCIPLINARY | ALEXANDRIA | LATE QUATERNARY EVOLUTION | HISTORY | Research | Rivers | Geoarchaeology | Floods | Egypt
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18. Holocene evolution of the western Orinoco Delta, Venezuela
by Andres Aslan and William A White and Andrew G Warne and Edgar H Guevara
Geological Society of America. Geological Society of America Bulletin, ISSN 0016-7606, 04/2003, Volume 115, Issue 4, p. 479
  The pristine nature of the Orinoco Delta of eastern Venezuela provides unique opportunities to study the geologic processes and environments of a major... 
Geology | Basins
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19. Full Text Late Quaternary Evolution of the Northwest Nile Delta and Adjacent Coast in the Alexandria Region, Egypt
by Andrew G. Warne and Daniel Jean Stanley
Journal of Coastal Research, ISSN 0749-0208, 1/1993, Volume 9, Issue 1, pp. 26 - 64
The late Pleistocene to Recent evolution of the Alexandria region, Egypt, is interpreted by sedimentologic- stratigraphic study of radiocarbon- dated borings.... 
Sand | Coasts | Geological facies | Canals | Lagoons | Lakes | Carbonates | Sediments | Sea level | Mud | NEOTECTONISM | HEAVY MINERALS | SEDIMENTS | MARYUT LAKE | GYPSUM NODULES | PALEOCLIMATIC OSCILLATIONS | NILE DELTA | ABU-QIR LAGOON | AFRICA | ENVIRONMENTAL SCIENCES | SUBSIDENCE | GEOGRAPHY, PHYSICAL | GEOSCIENCES, MULTIDISCIPLINARY | ALEXANDRIA | LAKE MARIUT | DEPOSITS | PALEOGEOGRAPHY | CARBONATE RIDGES | MEDITERRANEAN COAST | TIN-COMPOUNDS
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20. Drainage-basin-scale geomorphic analysis to determine reference conditions for ecologic restoration--Kissimmee River, Florida
by Andrew G Warne and Louis A Toth and William A White
Geological Society of America. Geological Society of America Bulletin, ISSN 0016-7606, 06/2000, Volume 112, Issue 6, p. 884
  Major controls on the retention, distribution, and discharge of surface water in the historic (precanal) Kissimmee drainage basin and river were investigated... 
Hydrology | Ecosystems | Rivers | Environmental management
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