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1. Full Text Activating mutations in Kir6.2 and neonatal diabetes: New clinical syndromes, new scientific insights, and new therapy
by Hattersley, Andrew T and Ashcroft, Frances M
Diabetes (New York, N.Y.), ISSN 0012-1797, 09/2005, Volume 54, Issue 9, pp. 2503 - 2513
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Phenotype | Diabetes Mellitus, Type 1 - physiopathology | Humans | Potassium Channels, Inwardly Rectifying - physiology | Diabetes Mellitus, Type 1 - genetics | Genotype | Potassium Channels, Inwardly Rectifying - genetics | Protein Conformation | Mutation | Potassium Channels, Inwardly Rectifying - chemistry | Infant, Newborn | Infants (Newborn) | Care and treatment | Diabetes | Research | Diseases | Index Medicus | Abridged Index Medicus
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2. Full Text Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study
by Rawshani, Araz and Sattar, Naveed and Franzén, Stefan and Rawshani, Aidin and Hattersley, Andrew T and Svensson, Ann-Marie and Eliasson, Björn and Gudbjörnsdottir, Soffia and Institute of Medicine, Department of Molecular and Clinical Medicine and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
The Lancet (British edition), ISSN 0140-6736, 08/2018, Volume 392, Issue 10146, pp. 477 - 486
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiovascular Diseases - etiology | Age Factors | Humans | Proportional Hazards Models | Child, Preschool | Infant | Male | Sweden - epidemiology | Diabetes Complications - mortality | Diabetes Mellitus, Type 1 - mortality | Young Adult | Adolescent | Age of Onset | Cardiovascular Diseases - epidemiology | Adult | Female | Registries | Child | Infant, Newborn | Cohort Studies | Stroke (Disease) | Heart | Sweden | Type 1 diabetes | Analysis | Atrial fibrillation | Mortality | Development and progression | Youth | Teenagers | Heart attack | Target marketing | Myocardial infarction | Heart attacks | Cardiovascular disease | Diabetes mellitus (insulin dependent) | Risk factors | Fibrillation | Blood pressure | Diagnosis | Heart diseases | Age | Cerebral infarction | Stroke | Young adults | Diabetes mellitus | Health risks | Patients | Coronary artery disease | Studies | Lungs | Infarction | Adults | Diabetes | Cardiovascular diseases | Health risk assessment | Index Medicus | Abridged Index Medicus | glycemic control | mellitus | thickness | lowering therapy | American-Heart-Association | individuals | endothelial dysfunction | Kardiologi | Cardiac and Cardiovascular Systems | scientific statement | Endokrinologi och diabetes | general-population | children | Endocrinology and Diabetes
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3. Full Text Precision diabetes: learning from monogenic diabetes
by Hattersley, Andrew T and Patel, Kashyap A
Diabetologia, ISSN 0012-186X, 5/2017, Volume 60, Issue 5, pp. 769 - 777
Type 2 diabetes | Human Physiology | KCNJ11 | Metabolic Diseases | Monogenic diabetes | Internal Medicine | HNF1A | Maturity onset diabetes of the young | Review | GCK | Precision diabetes | MODY | Medicine & Public Health | Precision medicine | HNF4A | Neonatal diabetes | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Diabetes Mellitus, Type 2 - metabolism | Diabetes Mellitus, Type 2 - pathology | Mutation - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Precision Medicine - methods | Infants (Newborn) | Medical colleges | Hypoglycemic agents | Index Medicus
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4. Full Text Type 2 Diabetes, SGLT2 Inhibitors, and Glucose Secretion
by Hattersley, Andrew T and Thorens, Bernard
The New England journal of medicine, ISSN 0028-4793, 09/2015, Volume 373, Issue 10, pp. 974 - 976
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Glucosides - pharmacology | Sodium-Glucose Transporter 2 - metabolism | Glucagon-Secreting Cells - metabolism | Humans | Glucose - metabolism | Benzhydryl Compounds - pharmacology | Sodium-Glucose Transporter 1 - metabolism | Diabetes Mellitus, Type 2 - metabolism | Glucagon - secretion | Diabetes Mellitus, Type 2 - drug therapy | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Type 2 diabetes | Symptomatology | Care and treatment | Dapagliflozin | Blood sugar | Analysis | Dosage and administration | Glucose transporter | Inhibitor drugs | Secretion | Diabetes mellitus | Reabsorption | Glucose | Insulin | Hyperglycemia | Sodium | Diabetes | Islets of Langerhans | Pancreas | Drug therapy | Diabetes mellitus (non-insulin dependent) | Index Medicus | Abridged Index Medicus
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5. Full Text Genetic Epidemiology 5 - What makes a good genetic association study?
by Hattersley, AT and McCarthy, MI
The Lancet (British edition), ISSN 0140-6736, 10/2005, Volume 366, Issue 9493, pp. 1315 - 1323
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Genetic aspects | Epidemiology | Epidemiologic methods | Analysis | Genetics | Genes
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6. Full Text Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk
by Hana Lango and Colin N.A. Palmer and Andrew D. Morris and Eleftheria Zeggini and Andrew T. Hattersley and Mark I. McCarthy and Timothy M. Frayling and Michael N. Weedon and UK Type Diab Genetics Consortium and UK Type 2 Diabetes Genetics Consortium and the U.K. Type 2 Diabetes Genetics Consortium
Diabetes (New York, N.Y.), ISSN 0012-1797, 11/2008, Volume 57, Issue 11, pp. 3129 - 3135
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Body Mass Index | Genetic Predisposition to Disease - genetics | Age Factors | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Diabetes Mellitus, Type 2 - prevention & control | Genotype | Male | Female | ROC Curve | Aged | Polymorphism, Single Nucleotide | Diabetes Mellitus, Type 2 - pathology | Type 2 diabetes | Genetic aspects | Research | Risk factors | Index Medicus | Abridged Index Medicus | Genetics
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7. Full Text Switching from Insulin to Oral Sulfonylureas in Patients with Diabetes Due to Kir6.2 Mutations
by Pearson, Ewan R and Flechtner, Isabelle and Njølstad, Pål R and Malecki, Maciej T and Flanagan, Sarah E and Larkin, Brian and Ashcroft, Frances M and Klimes, Iwar and Codner, Ethel and Iotova, Violeta and Slingerland, Annabelle S and Shield, Julian and Robert, Jean-Jacques and Holst, Jens J and Clark, Penny M and Ellard, Sian and Søvik, Oddmund and Polak, Michel and Hattersley, Andrew T and Neonatal Diabet Int Collaborative and Neonatal Diabetes International Collaborative Group
The New England journal of medicine, ISSN 0028-4793, 08/2006, Volume 355, Issue 5, pp. 467 - 477
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Glycated Hemoglobin A - analysis | Tolbutamide - pharmacology | Diabetes Mellitus - genetics | Humans | Infant | Male | Sulfonylurea Receptors | Potassium Channels - metabolism | Insulin-Secreting Cells - metabolism | Sulfonylurea Compounds - pharmacology | ATP-Binding Cassette Transporters - metabolism | Glyburide - therapeutic use | Female | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Glyburide - adverse effects | Infant, Newborn | Hypoglycemic Agents - therapeutic use | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Potassium Channels, Inwardly Rectifying - genetics | Receptors, Drug - metabolism | Insulin-Secreting Cells - drug effects | Heterozygote | Mutation | Hypoglycemic Agents - adverse effects | Potassium Channels, Inwardly Rectifying - metabolism | Insulin - therapeutic use | Receptors, Drug - antagonists & inhibitors | ATP-Binding Cassette Transporters - antagonists & inhibitors | Cohort Studies | Care and treatment | Control | Blood sugar | Hypoglycemic sulfonylureas | Sulfonylurea compounds | Insulin | Health aspects | Diabetes | Potassium | Index Medicus | Abridged Index Medicus
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8. Full Text Type 1 diabetes genetic risk score: A novel tool to discriminate monogenic and type 1 diabetes
by Patel, Kashyap A and Oram, Richard A and Flanagan, Sarah E and De Franco, Elisa and Colclough, Kevin and Shepherd, Maggie and Ellard, Sian and Weedon, Michael N and Hattersley, Andrew T
Diabetes (New York, N.Y.), ISSN 0012-1797, 07/2016, Volume 65, Issue 7, pp. 2094 - 2099
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Diagnosis, Differential | Genetic Predisposition to Disease | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Type 1 - genetics | Genotype | Male | Young Adult | Diabetes Mellitus, Type 1 - diagnosis | Diabetes Mellitus, Type 2 - diagnosis | Adolescent | Adult | Female | Mutation | Genetics | Care and treatment | Research | Biological markers | Type 1 diabetes | Genetic variation | Diabetes | Genes | Maturity | Index Medicus | Abridged Index Medicus
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9. Full Text Mutations in hepatocyte nuclear factor-1β and their related phenotypes
by Edghill, E L and Bingham, C and Ellard, S and Hattersley, A T
Journal of medical genetics, ISSN 0022-2593, 01/2006, Volume 43, Issue 1, pp. 84 - 90
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Cardiology. Vascular system | General aspects. Genetic counseling | Biological and medical sciences | Medical sciences | Medical genetics | renal cysts | HNF‐1β | RCAD syndrome | genetics | MODY | Medical Genetics in Practice | maturity‐onset diabetes of the young
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10. Full Text GATA6 haploinsufficiency causes pancreatic agenesis in humans
by Allen, H.L and Flanagan, S.E and Shaw-Smith, C and Franco, E. De and Akerman, I and Caswell, R and Ferrer, J and Hattersley, A.T and Ellard, S and Aanstoot, H.J and Aberg, E and Adolfsson, P and Anthony, M and Batlle, M and Bruining, J and Bühr, P and Cummings, E and Edge, J and Garcia-Hurtado, J and Hathout, E and Ho, J and Jeffries, C and Temple, I.K and Kaufman, E and Kotori, V.M and Krijger, R. de and Kummer, M and Mackay, D and Mace, J and Noordam, C and O'Brien, F and Rubio-Cabezas, O and Shield, J and Skidmore, D and White, S and Zanier, U and Int Pancreatic Agenesis Consortium and International Pancreatic Agenesis Consortium and the International Pancreatic Agenesis Consortium and Sahlgrenska akademin and Institute of Clinical Sciences, Department of Pediatrics and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, Avdelningen för pediatrik and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 2011, Volume 44, Issue 1, pp. 20 - 22
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Pancreas - abnormalities | Phenotype | GATA6 Transcription Factor - genetics | Humans | Haploinsufficiency | Agenesis | Transcription factors | Gene mutations | Pancreatic diseases | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Studies | Medical research | Genomes | Mutation | Genetic testing | Pancreas | Deoxyribonucleic acid--DNA | Index Medicus | Pediatrics | GATA6 Transcription Factor | genetics | Pediatrik | abnormalities
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