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Nature Reviews Microbiology, ISSN 1740-1526, 10/2005, Volume 3, Issue 10, pp. 819 - 823
  Chagas disease is a debilitating human illness caused by infection with the protozoan Trypanosoma cruzi. A capacity to invade and replicate within many... 
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 09/2019, Volume 87, Issue 12
ABSTRACT The molecular mechanisms underlying biological differences between two Leishmania species that cause cutaneous disease, L. major and L. amazonensis,... 
Journal Article
International Journal for Parasitology, ISSN 0020-7519, 05/2019, Volume 49, Issue 6, pp. 423 - 427
The Leishmania plasma membrane transporter Leishmania Iron Regulator 1 (LIR1) facilitates iron export and is required for parasite virulence. By modulating... 
Drug target | Cationic ferritin | Amastigotes | Virulence | Endocytic pathway | Heme
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 12/2015, Volume 211, Issue 6, pp. 1193 - 1193
Cells rapidly repair plasma membrane (PM) damage by a process requiring Ca...-dependent lysosome exocytosis. Acid sphingomyelinase (ASM) released from... 
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2016, Volume 12, Issue 12
  Iron, an essential co-factor of respiratory chain proteins, is critical for mitochondrial function and maintenance of its redox balance. We previously... 
Mitochondria | Parasitic diseases | Plasmids | Laboratories | Cloning | Mortality | Colleges & universities | Iron | Parasites | Mammals | Gene expression | Deoxyribonucleic acid--DNA
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1
  Leishmania parasites infect macrophages, cells that play an important role in organismal iron homeostasis. By expressing ferroportin, a membrane protein... 
Proteins | Competition | Peptides | Parasitic diseases | Homeostasis | Iron | Software | Parasites | Mammals
Journal Article
Methods in molecular biology (Clifton, N.J.), 2017, Volume 1594, p. 205
Elevation in the cytosolic Ca concentration triggers exocytosis of lysosomes in many cell types. This chapter describes a method to detect lysosomal exocytosis... 
Epitopes - analysis | Animals | Lysosomes - metabolism | Exocytosis - genetics | Calcium - metabolism | Humans | Lysosomal-Associated Membrane Protein 1 - metabolism | Cell Membrane - metabolism | Exocytosis - physiology
Journal Article
Current Biology, ISSN 0960-9822, 04/2018, Volume 28, Issue 8, pp. R392 - R397
Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | DAMAGE | CELL BIOLOGY | Cell death | Cell membranes
Journal Article
The Journal of General Physiology, ISSN 0022-1295, 03/2013, Volume 141, Issue 3, pp. i7 - i7
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2012, Volume 122, Issue 7, pp. 2352 - 2354
The immune system's battle against pathogens includes the "respiratory burst," a rapid release of ROS from leukocytes, thought to play a role in destroying the... 
MEDICINE, RESEARCH & EXPERIMENTAL | LEISHMANIA-AMAZONENSIS | TRANSFERRIN | DNA | ACQUISITION | DISEASE | Parasitemia - parasitology | Chagas Disease - parasitology | Animals | Oxidative Stress | Trypanosoma cruzi - physiology | Infection | Prevention | Antioxidants | Causes of | Oxidative stress | Health aspects
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