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Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2009, Volume 15, Issue 24, pp. 7652 - 7657
Purpose: The association of chemotherapy and antiangiogenic drugs has shown efficacy in clinical oncology. However, there is a need for biomarkers that allow... 
metronomic chemotherapy | Angiogenesis | antiangiogenesis | VEGF | circulating endothelial cells | CAPECITABINE | SURVIVAL | THERAPY | ONCOLOGY | CYCLOPHOSPHAMIDE | VIABILITY | PHASE-II | RECURRENT OVARIAN-CANCER | TUMOR ANGIOGENESIS
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, p. 18673
Journal Article
Carcinogenesis, ISSN 0143-3334, 5/2014, Volume 35, Issue 5, pp. 1055 - 1066
Summary We have investigated the effect of metformin on the mechanisms of angiogenesis. We show that metformin, particularly in the context of obesity,... 
IN-VITRO | ACTIVATED PROTEIN-KINASE | ONCOLOGY | NITRIC-OXIDE | CYP1B1 | ADIPONECTIN STIMULATES ANGIOGENESIS | TUMOR ANGIOGENESIS | CANCER PREVENTION | GROWTH-FACTOR | NF-KAPPA-B | TYPE-2 DIABETES-MELLITUS | Human Umbilical Vein Endothelial Cells | Neoplasms - metabolism | Neovascularization, Physiologic - drug effects | AMP-Activated Protein Kinases - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Adipose Tissue - cytology | Male | Gene Expression Profiling | Stem Cells - cytology | Stem Cells - metabolism | Neoplasms - genetics | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Vascular Endothelial Growth Factor A - pharmacology | Disease Models, Animal | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | Metformin - pharmacology | Angiogenesis Inhibitors - pharmacology | Enzyme Activation - drug effects | Aryl Hydrocarbon Hydroxylases - metabolism | Neoplasms - drug therapy | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Endothelial Cells - cytology | Neovascularization, Pathologic - drug therapy | Cytochrome P-450 CYP1B1 | Stem Cells - drug effects | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Neoplasms - pathology | Adipose Tissue - drug effects | Cluster Analysis | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | Original Manuscript
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e114713
Background: The endothelium is not a homogeneous organ. Endothelial cell heterogeneity has been described at the level of cell morphology, function, gene... 
PROGENITOR CELLS | BREAST-CANCER | HETEROGENEITY | LUNG-CANCER | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FLOW-CYTOMETRY | PATHOLOGICAL ANGIOGENESIS | IDENTIFICATION | METRONOMIC CHEMOTHERAPY | Neoplastic Cells, Circulating - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Neoplastic Cells, Circulating - metabolism | Male | CD146 Antigen - genetics | Antigens, CD - genetics | CD146 Antigen - blood | Antigens, CD - analysis | Neoplasms - blood | Glioblastoma - genetics | Neoplasms - genetics | Adult | Female | Neoplasm Proteins - genetics | CD146 Antigen - analysis | Endothelial Cells - metabolism | GPI-Linked Proteins - analysis | Glioblastoma - blood | Antigens, CD - blood | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Glioblastoma - pathology | Breast Neoplasms - blood | GPI-Linked Proteins - blood | Neoplasm Proteins - analysis | Neoplasm Proteins - blood | Aged | Endothelial Cells - pathology | Neoplasms - pathology | GPI-Linked Proteins - genetics | Flow cytometry | Laboratories | Glioblastoma | Cytology | Oncology | Identification | Kinases | Blood | CD45 antigen | Cell morphology | Angiogenesis | Embryogenesis | Peripheral blood | Deoxyribonucleic acid--DNA | Antigens | Phenotypes | Hematology | Breast cancer | Gene expression | Cadherin | Patients | Endothelial cells | Endothelium | Embryonic growth stage | Polymerase chain reaction | White blood cells | Cytometry | Blood circulation | Ribonucleic acids | Viability | Cancer | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e74345
Background: Recent data suggest that circulating endothelial and progenitor cells (CECs and CEPs, respectively) may have predictive potential in cancer... 
PROGENITOR CELLS | PHASE-II TRIAL | COLORECTAL-CANCER PATIENTS | 1ST-LINE CHEMOTHERAPY | VEGF | MULTIDISCIPLINARY SCIENCES | RESPONSE ASSESSMENT | MALIGNANT GLIOMAS | CLINICAL-VALUE | FLOW-CYTOMETRY | HEMATOPOIETIC STEM | Prognosis | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antineoplastic Agents - administration & dosage | Neoplasm Proteins - metabolism | Antigens, CD - metabolism | Bevacizumab | Young Adult | Angiogenesis Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Adult | Camptothecin - administration & dosage | Female | Glioblastoma - metabolism | Camptothecin - analogs & derivatives | Endothelial Cells - metabolism | Neoplasm Recurrence, Local | Immunophenotyping | Treatment Outcome | Disease Progression | GPI-Linked Proteins - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Glioblastoma - pathology | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | Medical research | Care and treatment | Relapse | Antibodies | Development and progression | Diseases | Endothelium | Viral antibodies | Chemotherapy | Gliomas | Medicine, Experimental | Angiogenesis inhibitors | Vascular endothelial growth factor | Cancer | Flow cytometry | Enzymes | Hematology | Glioblastoma | Oncology | Cancer therapies | Survival | Patients | Endothelial cells | Angiogenesis | Irinotecan | Cytometry | Magnetic resonance imaging | Stem cells | Cells (biology) | Bone marrow | Lesions | Tumors
Journal Article