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Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific... 
UNFOLDED PROTEIN RESPONSE | PATHWAY | ER STRESS | HOST-DEFENSE | ENDOPLASMIC-RETICULUM STRESS | FRANCISELLA-TULARENSIS INFECTION | IMMUNOLOGY | LIVE VACCINE STRAIN | INFLAMMATORY RESPONSE | NEGATIVE REGULATOR | SYSTEMS BIOLOGY | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 6/2008, Volume 320, Issue 5882, pp. 1492 - 1496
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 2016, Volume 473, Issue 17, pp. 2603 - 2610
Journal Article
Oncogenesis, ISSN 2157-9024, 03/2019, Volume 8, Issue 3, pp. 12 - 10
In cancer, activation of X-box binding protein (XBP1) has a critical role in tumorigenesis and cancer progression. Transcriptional regulatory mechanism of XBP1... 
TUMOR-SUPPRESSOR | DEGRADATION | ONCOLOGY | UBIQUITIN LIGASE | NF-KAPPA-B | EXPRESSION | NF-κB protein | Phosphorylation | Transcription factors | Transcription | Activator protein 1 | Myc protein | E2F1 protein | Cullin | Signal transduction | E2F protein | Ubiquitination | Feedback | Tumorigenesis | Ubiquitin-protein ligase | Cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2012, Volume 287, Issue 4, pp. 2558 - 2567
Hepatic insulin resistance has been attributed to both increased endoplasmic reticulum (ER) stress and accumulation of intracellular lipids, specifically... 
GLUCOSE-HOMEOSTASIS | ENERGY-EXPENDITURE | MESSENGER-RNA | STEATOSIS | FATTY LIVER-DISEASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | DIET-INDUCED OBESITY | TRANSCRIPTION FACTOR | RECEPTOR SUBSTRATE-1 | Endoribonucleases - genetics | Phosphorylation | Endoplasmic Reticulum - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Insulin Receptor Substrate Proteins - metabolism | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Heat-Shock Proteins - genetics | Eukaryotic Initiation Factor-2 - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Insulin Receptor Substrate Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Endoplasmic Reticulum - genetics | Endoribonucleases - metabolism | Heat-Shock Proteins - metabolism | Liver - metabolism | Insulin Resistance | Protein-Serine-Threonine Kinases - genetics | Lipid Metabolism | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Mice, Knockout | Transcription Factors - metabolism | Animals | Endoplasmic Reticulum Stress | Eukaryotic Initiation Factor-2 - genetics | Mice | Index Medicus | Liver Metabolism | ER Stress | Protein Kinase C (PKC) | Diacylglycerol | Glucose Metabolism | Ceramide | Metabolism | Gluconeogenesis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2003, Volume 100, Issue 17, pp. 9946 - 9951
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 21, pp. 8885 - 8890
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 829 - 837
The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in... 
ALTERNATIVELY ACTIVATED MACROPHAGES | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | ER-STRESS | BONE-MARROW | DISEASE | GENE-EXPRESSION | MICE | IMMUNOLOGY | PLASMA-CELL DIFFERENTIATION | MAJOR BASIC-PROTEIN | Endoribonucleases - genetics | Eosinophils - metabolism | Humans | Gene Expression Profiling | Endoplasmic Reticulum Stress - genetics | Eosinophils - immunology | Granulocyte Precursor Cells - ultrastructure | Endoplasmic Reticulum Stress - immunology | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | Signal Transduction - immunology | Flow Cytometry | Gene Expression - immunology | HEK293 Cells | Transcription Factors - immunology | Protein-Serine-Threonine Kinases - metabolism | Granulocyte Precursor Cells - immunology | Eosinophils - ultrastructure | Microscopy, Electron, Transmission | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Granulocyte Precursor Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Mice, Knockout | Transcription Factors - metabolism | Cell Differentiation - immunology | Microscopy, Confocal | Animals | Protein-Serine-Threonine Kinases - immunology | Mice, Inbred BALB C | Endoribonucleases - immunology | Transcription factors | Genetic aspects | Properties | Cell differentiation | Eosinophils | Immune system | Index Medicus
Journal Article
Journal Article