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Molecular and Cellular Biology, ISSN 0270-7306, 11/2013, Volume 33, Issue 21, pp. 4152 - 4165
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77383
There is large literature describing in vitro experiments on heat shock protein (hsp)B1 but understanding of its function in vivo is limited to studies in mice... 
HUMAN HSP27 | PHOSPHORYLATION | TRISTETRAPROLIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GENE-EXPRESSION | RESISTANCE | MAPKAP KINASE-2 | NECROSIS-FACTOR-ALPHA | STRESS | HEAT-SHOCK-PROTEIN-27 | Skin - cytology | Cell Proliferation | Skin - metabolism | Epithelial Cells - drug effects | Exons - genetics | Peritonitis - chemically induced | Wound Healing | Skin - injuries | HSP27 Heat-Shock Proteins - deficiency | Interleukin-1 - pharmacology | Gene Expression Regulation - drug effects | HSP27 Heat-Shock Proteins - genetics | Zymosan - adverse effects | Collagen - metabolism | Peritonitis - pathology | Animals | Fibroblasts - drug effects | Peritonitis - physiopathology | Fibroblasts - cytology | Mice | Cell Cycle - drug effects | Epithelial Cells - cytology | Interleukin-6 - metabolism | Fibroblasts - metabolism | Animal experimentation | Wound healing | Interleukins | RNA | Collagen | Genes | Heat shock proteins | Gene expression | Cell proliferation | GTP-binding protein | Animal models | Phosphorylation | Interleukin | Kinases | Interleukin 6 | Proteins | Cyclin-dependent kinase | Cell growth | Rodents | Cell cycle | Fibroblasts | Tumor necrosis factor-TNF | Peritonitis | Cyclin-dependent kinases | Neutrophils | Rheumatology | Inflammation | Cyclin-dependent kinase inhibitor p21 | S phase | Cyclin-dependent kinase inhibitor p27 | Infiltration | In vivo methods and tests | Cancer | Apoptosis | Heat shock
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2009, Volume 583, Issue 12, pp. 1933 - 1938
p38 mitogen-activated protein kinase (MAPK) stabilises pro-inflammatory mediator mRNAs by inhibiting AU-rich element (ARE)-mediated decay. We show that in... 
Tristetraprolin | p38 Mitogen-activated protein kinase | Interleukin-10 | COX-2 | glutathione-S-transferase | CXCL1 | BMDM | TNF | LPS | mitogen-activated protein kinase | TTP | UTR | chemokine (C-X-C motif) ligand 1 | Act D | bone marrow-derived macrophages | foetal calf serum | glyceraldehyde-3-phosphate dehydrogenase | interleukin | tristetraprolin | actinomycin D | untranslated region | GST | MAPK | ARE | AU-rich element | FCS | tumour necrosis factor | lipopolysaccharide | GAPDH | ACTIVATED PROTEIN-KINASE | CYCLOOXYGENASE-2 | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | NECROSIS-FACTOR-ALPHA | ARTHRITIS | CELL BIOLOGY | REGULATOR | DEADENYLATION | BIOPHYSICS | AU-RICH ELEMENTS | GENE-EXPRESSION | Mice, Inbred C57BL | RNA, Messenger - genetics | RNA Stability | RNA, Messenger - metabolism | MAP Kinase Signaling System | Mice, Knockout | Tristetraprolin - deficiency | Macrophages - metabolism | Animals | Tristetraprolin - genetics | Base Sequence | Interleukin-10 - antagonists & inhibitors | Interleukin-10 - genetics | Inflammation Mediators - metabolism | Interleukin-6 - biosynthesis | Tristetraprolin - metabolism | Mice | p38 Mitogen-Activated Protein Kinases - metabolism | In Vitro Techniques | Interleukin-12 Subunit p40 - biosynthesis | Phosphates | Messenger RNA | Interleukins | Glutathione transferase | Macrophages | Protein kinases | Mitogens | Sugars | Monosaccharides
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 03/2007, Volume 1773, Issue 3, pp. 330 - 341
The regulators of calcineurin (RCAN) proteins, previously known as calcipressins, have been considered to be a well conserved family from yeast to human based... 
DSCR1L2 | Immunosuppression | Calcineurin | RCAN3 | Cytokine | NFAT | cytokine | CELLS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR NFAT1 | ZAKI-4 | immunosuppression | calcineurin | FAMILY | CELL BIOLOGY | EVOLUTION | SEQUENCE ALIGNMENT | DSCR1 | CALCIUM | SYNDROME CRITICAL REGION | Genetic research | Gene expression | Analysis
Journal Article
The Journal of Biological Chemistry, ISSN 0021-9258, 4/2009, Volume 284, Issue 14, pp. 9394 - 9401
Calcineurin phosphatase plays a crucial role in T cell activation. Dephosphorylation of the nuclear factors of activated T cells (NFATs) by calcineurin is... 
Mechanisms of Signal Transduction
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0113902
The mechanistic target of rapamycin (mTOR) signaling pathway is highly conserved from yeast to humans. It senses various environmental cues to regulate... 
MESSENGER-RNA DEADENYLATION | CAF1 PROTEINS | DIFFERENTIALLY AFFECTS | INITIATION | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | DEGRADATION | TRANSLATION | SACCHAROMYCES-CEREVISIAE | DROSOPHILA | POLY(A) TAIL | Cell Line | Insulin - pharmacology | Phosphorylation | Protein Biosynthesis | Cell Size - drug effects | RNA, Messenger - genetics | Drosophila melanogaster - cytology | Gene Expression Regulation | 3' Untranslated Regions - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Drosophila melanogaster - genetics | Promoter Regions, Genetic - genetics | RNA Stability - genetics | Ribonucleases - metabolism | Peptide Initiation Factors - metabolism | Peptide Initiation Factors - genetics | Animals | Carrier Proteins - metabolism | Transcription, Genetic | Drosophila Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Genetic research | RNA | Genetic translation | Genes | Protein binding | TOR protein | Deregulation | Yeast | Transcription | Homeostasis | Kinases | Proteins | Signal transduction | Cascades | Cues | Biodegradation | RNA-mediated interference | Drosophila | Translation initiation | Rapamycin | Gene expression | Insulin | Signaling | Cellular biology | Insects | 3' Untranslated regions | Regulatory mechanisms (biology) | Molecular biology | Cancer
Journal Article
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