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1. Full Text Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
by Quarraisha Abdool Karim and Salim S. Abdool Karim and Janet A. Frohlich and Anneke C. Grobler and Cheryl Baxter and Leila E. Mansoor and Ayesha B. M. Kharsany and Sengeziwe Sibeko and Koleka P. Mlisana and Zaheen Omar and Tanuja N. Gengiah and Silvia Maarschalk and Natasha Arulappan and Mukelisiwe Mlotshwa and Lynn Morris and Douglas Taylor and CAPRISA 004 Trial Grp and CAPRISA 004 Trial Group and on behalf of the CAPRISA 004 Trial Group
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5996, pp. 1168 - 1174
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of... 
Human sexual behavior | HIV infections | Antiinfectives | Gels | HIV | RESEARCH ARTICLES | Placebos | Experimentation | AIDS | Infections | Condoms | VAGINAL GEL | INDIVIDUALS | SOUTH-AFRICA | PROPHYLAXIS | IN-VITRO | TRANSMISSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | MALE CIRCUMCISION | RANDOMIZED CONTROLLED-TRIAL | CHALLENGES | HIV Infections - prevention & control | Anti-Infective Agents, Local - therapeutic use | Urban Population - statistics & numerical data | HIV Infections - epidemiology | Humans | Anti-Infective Agents, Local - adverse effects | Drug Resistance, Viral | Administration, Intravaginal | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Tenofovir | Young Adult | Adenine - adverse effects | HIV-1 - physiology | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Vaginal Creams, Foams, and Jellies | Rural Population - statistics & numerical data | Sexual Behavior | Adenine - analogs & derivatives | Double-Blind Method | Organophosphonates - therapeutic use | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | South Africa - epidemiology | Organophosphonates - adverse effects | Adenine - administration & dosage | Pregnancy | Organophosphonates - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Adolescent | Patient Compliance | Pregnancy Outcome | Prevention | Anti-infective agents | Research | HIV infection
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2. Full Text Symptomatic Vaginal Discharge Is a Poor Predictor of Sexually Transmitted Infections and Genital Tract Inflammation in High-Risk Women in South Africa
by Koleka Mlisana and Nivashnee Naicker and Lise Werner and Lindi Roberts and Francois van Loggerenberg and Cheryl Baxter and Jo-Ann S. Passmore and Anneke C. Grobler and A. Willem Sturm and Carolyn Williamson and Katharina Ronacher and Gerhard Walzl and Salim S. Abdool Karim
The Journal of Infectious Diseases, ISSN 0022-1899, 7/2012, Volume 206, Issue 1, pp. 6 - 14
Background. Diagnosis and treatment of sexually transmitted infections (STIs) is a public health priority, particularly in regions where the incidence of human... 
HIV/AIDS | Bacterial vaginosis | HIV infections | Genitalia | Sexually transmitted diseases | Cytokines | HIV | Human herpesvirus 2 | Infections | Symptoms | HIV 1 | INFECTIOUS DISEASES | BARRIER FUNCTION | SYNDROMIC MANAGEMENT | MICROBIOLOGY | NECROSIS-FACTOR-ALPHA | RANDOMIZED CONTROLLED-TRIAL | SEX WORKERS | IMMUNOLOGY | VIRUS TYPE-1 | TRANSMISSION | ULCER DISEASE | EPITHELIAL MONOLAYERS | HIV-1 INFECTION | Prevalence | Follow-Up Studies | Cytokines - analysis | HIV Infections - epidemiology | Humans | Genitalia, Female - virology | Sexually Transmitted Diseases - epidemiology | Sexually Transmitted Diseases - diagnosis | Genitalia, Female - pathology | Incidence | HIV-1 - isolation & purification | HIV Infections - diagnosis | Vaginal Discharge - virology | Reproductive Tract Infections - diagnosis | Adult | Female | Inflammation - diagnosis | Sexually Transmitted Diseases - virology | HIV Infections - virology | South Africa - epidemiology | Inflammation - virology | Reproductive Tract Infections - epidemiology | Inflammation - epidemiology | Reproductive Tract Infections - virology | Vaginal Discharge - diagnosis | Cohort Studies | Vaginal diseases | Research | Diagnosis | Analysis | Major and Brief Reports
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3. Full Text Multiple imputation in the presence of an incomplete binary variable created from an underlying continuous variable
by Grobler, Anneke C and Lee, Katherine
Biometrical journal. Biometrische Zeitschrift, ISSN 0323-3847, 07/2019
Multiple imputation (MI) is used to handle missing at random (MAR) data. Despite warnings from statisticians, continuous variables are often recoded into... 
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4. Full Text The impact of missing data on clinical trials: a re-analysis of a placebo controlled trial of Hypericum perforatum (St Johns wort) and sertraline in major depressive disorder
by Grobler, Anneke C and Matthews, Glenda and Molenberghs, Geert
Psychopharmacology, ISSN 0033-3158, 5/2014, Volume 231, Issue 9, pp. 1987 - 1999
Hypericum perforatum (St John's wort) is used to treat depression, but the effectiveness has not been established. Recent guidelines described the analysis of... 
Hypericum perforatum | Antidepressant | Neurosciences | Missing at random | Bayesian | Missing not at random | St John's wort | Sertraline | Herbal medicine | Biomedicine | Pharmacology/Toxicology | Multiple imputation | Psychiatry | Hamilton depression scale | PSYCHIATRY | INFERENCE | NEUROSCIENCES | RANDOMIZED CONTROLLED TRIAL | TOLERABILITY | PHARMACOLOGY & PHARMACY | Double-Blind Method | Follow-Up Studies | Humans | Hypericum | Male | Treatment Outcome | Models, Statistical | Patient Dropouts | Antidepressive Agents - therapeutic use | Psychiatric Status Rating Scales | Sensitivity and Specificity | Sertraline - therapeutic use | Female | Phytotherapy | Longitudinal Studies | Plant Extracts - therapeutic use | Depressive Disorder, Major - drug therapy | Complications and side effects | Usage | Physiological aspects | Dosage and administration | Research | Drug therapy | Major depressive disorder | St. John's wort | Clinical trials | Mental depression | Psychopharmacology | antidepressant | missing not at random | multiple imputation | missing at random | St John’s Wort | hypericum perforatum | herbal medicine | sertraline
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5. Full Text Cost-Effectiveness of Initiating Antiretroviral Therapy at Different Points in TB Treatment in HIV-TB Coinfected Ambulatory Patients in South Africa
by Naidoo, Kogieleum and Grobler, Anneke C and Deghaye, Nicola and Reddy, Tarylee and Gengiah, Santhanalakshmi and Gray, Andrew and Abdool Karim, Salim
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 08/2015, Volume 69, Issue 5, pp. 576 - 584
OBJECTIVE:Initiation of antiretroviral therapy (ART) during tuberculosis (TB) treatment improves survival in TB-HIV coinfected patients. In patients with CD4... 
ART integration | cost-effectiveness | SAPiT trial | tuberculosis | INFECTIOUS DISEASES | START | RESOURCE-LIMITED SETTINGS | IMMUNOLOGY | INTEGRATION | TUBERCULOSIS | Tuberculosis - epidemiology | Anti-HIV Agents - economics | Drug Administration Schedule | HIV Infections - economics | HIV Infections - epidemiology | Humans | South Africa - epidemiology | Tuberculosis - complications | Tuberculosis - economics | Anti-HIV Agents - administration & dosage | Antitubercular Agents - economics | Health Care Costs | Cost-Benefit Analysis | Tuberculosis - drug therapy | HIV Infections - complications | Antitubercular Agents - administration & dosage | Anti-HIV Agents - therapeutic use | HIV Infections - drug therapy | Antitubercular Agents - therapeutic use | Variables | Antiretroviral drugs | Effectiveness | Tuberculosis | Human immunodeficiency virus--HIV
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6. Full Text Disclosure of Microbicide Gel Use to Sexual Partners: Influence on Adherence in the CAPRISA 004 Trial
by Mngadi, Kathryn Therese and Maarschalk, Silvia and Grobler, Anneke C and Mansoor, Leila E and Frohlich, Janet A and Madlala, Bernadette and Ngcobo, Nelisiwe and Abdool Karim, Salim S and Abdool Karim, Quarraisha
AIDS and Behavior, ISSN 1090-7165, 5/2014, Volume 18, Issue 5, pp. 849 - 854
Young women in sub-Saharan Africa are disproportionately affected by HIV, making the development of women initiated and controlled methods of prevention,... 
Adherence | Partner disclosure | Public Health | Microbicides | Medicine & Public Health | Infectious Diseases | Health Psychology | HIV prevention | Pre-exposure prophylaxis | ZIMBABWE | SOCIAL SCIENCES, BIOMEDICAL | VAGINAL MICROBICIDE | ACCEPTABILITY | WOMEN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INFECTION | PREEXPOSURE PROPHYLAXIS | PARTICIPANTS | HIV Infections - prevention & control | Adenine - analogs & derivatives | Medication Adherence - psychology | Gels | Humans | Disclosure | Socioeconomic Factors | Adenine - administration & dosage | Sexual Behavior - psychology | Tenofovir | Young Adult | Organophosphonates - administration & dosage | Anti-Infective Agents - administration & dosage | Adolescent | Adult | Female | Interviews as Topic | South Africa | Surveys and Questionnaires | Condoms - utilization | Sexual Partners | Prevention | Anti-infective agents | Dosage and administration | Research | HIV infection | Antimicrobial agents | Preventive medicine | Domestic partners | Compliance | Human immunodeficiency virus--HIV
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7. Full Text Associations between non-anaemic iron deficiency and outcomes following surgery for colorectal cancer: An exploratory study of outcomes relevant to prospective observational studies
by Miles, Lachlan F and Sandhu, Ravinder N S and Grobler, Anneke C and Heritier, Stephane and Burgess, Adele and Burbury, Kate L and Story, David A
Anaesthesia and Intensive Care, ISSN 0310-057X, 03/2019, Volume 47, Issue 2, pp. 152 - 159
Iron deficiency is common in colorectal cancer. Despite perioperative guidelines advocating for the correction of nonanaemic iron deficiency prior to major... 
Treatment | Surgery, Elective | Anemia | Iron deficiency anemia | Analysis | Hemoglobin | Colon (Anatomy) | Cancer | colonic neoplasms | elective surgical procedures | Anaemia, iron | Colorectal Neoplasms - surgery | Prospective Studies | Humans | Elective Surgical Procedures | Anemia, Iron-Deficiency | Cohort Studies | Blood transfusions | Heart failure | Postoperative period | Intensive care | Mortality | Colorectal cancer | Clinical trials | Infections | Iron | Laparoscopy | Patients | Morbidity | Cancer surgery | Studies | Hospitals | Antibiotics | Trends
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8. Full Text Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection
by Abdool Karim, Quarraisha and Abdool Karim, Salim S and Kharsany, Ayesha B.M and Baxter, Cheryl and Grobler, Anneke C and Werner, Lise and Kashuba, Angela and Mansoor, Leila E and Samsunder, Natasha and Mindel, Adrian and Gengiah, Tanuja N and Caprisa 004 Trial Grp and CAPRISA 004 Trial Group
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 6, pp. 530 - 539
Herpes simplex virus type 2 infection is a common sexually transmitted infection worldwide. Strategies to decrease transmission are needed. In this report from... 
ANTIBODIES | TRIAL | HIV PREVENTION | WOMEN | MEDICINE, GENERAL & INTERNAL | ORAL TENOFOVIR | ACQUISITION | PREVALENCE | PREEXPOSURE PROPHYLAXIS | HSV-2 | HIV Infections - prevention & control | HIV Seronegativity | Adenine - analogs & derivatives | Double-Blind Method | Follow-Up Studies | Gels | Humans | Kaplan-Meier Estimate | Organophosphonates - adverse effects | Administration, Intravaginal | Reverse Transcriptase Inhibitors - administration & dosage | Herpesvirus 2, Human | Adenine - administration & dosage | Incidence | Reverse Transcriptase Inhibitors - adverse effects | Tenofovir | Young Adult | Organophosphonates - administration & dosage | Adenine - adverse effects | Herpes Genitalis - prevention & control | Adult | Female | Herpes Genitalis - epidemiology | Prevention | Usage | Care and treatment | Sexually transmitted diseases | Herpes simplex virus | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Herpes viruses | Immunoglobulin G | Vagina | Herpes simplex | Infections | Preventive medicine | Seroconversion | Enzyme-linked immunosorbent assay | Pharmaceuticals
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9. Full Text Lung function: population epidemiology and concordance in Australian children aged 11-12 years and their parents
by Welsh, Liam and Kathriachchige, Gayan and Raheem, Tahmeed and Grobler, Anneke C and Wake, Melissa and Ranganathan, Sarath
BMJ open, ISSN 2044-6055, 07/2019, Volume 9, Issue Suppl 3, pp. 53 - 62
To describe the epidemiology of lung function in Australian children aged 11-12 years and their parents, and explore the degree of intergenerational... 
GLOBAL BURDEN | reference values | epidemiologic studies | PULMONARY-FUNCTION | ADOLESCENCE | CHILDHOOD | inheritance patterns | MEDICINE, GENERAL & INTERNAL | lung function | spirometry | children | DISEASE | RESEMBLANCE | COHORT | FAMILIAL AGGREGATION
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10. Full Text Health-related quality of life: population epidemiology and concordance in Australian children aged 11-12 years and their parents
by Catchpool, Max and Gold, Lisa and Grobler, Anneke C and Clifford, Susan A and Wake, Melissa
BMJ open, ISSN 2044-6055, 07/2019, Volume 9, Issue Suppl 3, pp. 157 - 164
To describe the distribution of health-related quality of life (HRQL) in a national sample of Australian children aged 11-12 years and their parents, and... 
well-being | reference values | epidemiologic studies | health-related quality of life | RELIABILITY | cross-sectional studies | inheritance patterns | MEDICINE, GENERAL & INTERNAL | children | ADOLESCENTS | VALIDITY | parents | correlation studies | UTILITY 9D
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11. Full Text Sleep: population epidemiology and concordance in Australian children aged 11-12 years and their parents
by Matricciani, Lisa and Fraysse, Francois and Grobler, Anneke C and Muller, Josh and Wake, Melissa and Olds, Timothy
BMJ open, ISSN 2044-6055, 07/2019, Volume 9, Issue Suppl 3, pp. 127 - 135
To describe objectively measured sleep characteristics in children aged 11-12 years and in parents and to examine intergenerational concordance of sleep... 
reference values | METAANALYSIS | epidemiologic studies | OBJECTIVELY-MEASURED SLEEP | sleep | inheritance patterns | SAMPLE | MEDICINE, GENERAL & INTERNAL | METHODOLOGY | children | RECOMMENDATIONS | ADOLESCENTS | WAKE PATTERNS | actigraphy | PHYSICAL-ACTIVITY | ASSOCIATION | DURATION
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12. Full Text Physical activity and sedentary activity: population epidemiology and concordance in Australian children aged 11-12 years and their parents
by Fraysse, François and Grobler, Anneke C and Muller, Josh and Wake, Melissa and Olds, Timothy
BMJ open, ISSN 2044-6055, 07/2019, Volume 9, Issue Suppl 3, pp. 136 - 146
To describe the epidemiology and parent-child concordance of objectively measured physical activity in a population-based sample of Australian parent-child... 
reference values | FITNESS | ASSOCIATIONS | epidemiologic studies | INTENSITY | EXERCISE | physical activity | inheritance patterns | AMERICAN | MEDICINE, GENERAL & INTERNAL | children | YOUTH | UP-IN-AUSTRALIA | ACCELEROMETER | actigraphy | HEALTH | BEHAVIORS
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13. Full Text Impact of a behavioral intervention, delivered by pediatricians or psychologists, on sleep problems in children with ADHD: a cluster-randomized, translational trial
by Hiscock, Harriet and Mulraney, Melissa and Heussler, Helen and Rinehart, Nicole and Schuster, Tibor and Grobler, Anneke C and Gold, Lisa and Bohingamu Mudiyanselage, Shalika and Hayes, Nicole and Sciberras, Emma
Journal of child psychology and psychiatry, and allied disciplines, ISSN 0021-9630, 06/2019
We have demonstrated the efficacy of a brief behavioral intervention for sleep in children with ADHD in a previous randomized controlled trial and now aim to... 
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