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PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e86447
Background: Although obesity has been associated with metabolic and cardiac disturbances, the carrier mechanisms for these responses are poorly understood.... 
CROSS-TALK | ZUCKER RATS | METABOLIC SYNDROME | SPONTANEOUSLY HYPERTENSIVE-RATS | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | HEART-FAILURE | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | ANGIOTENSIN-II | FATTY-ACIDS | EXPRESSION | Class Ia Phosphatidylinositol 3-Kinase - metabolism | Insulin Resistance | Losartan - pharmacology | Rats | Rats, Inbred WKY | Blood Glucose | Male | Myocardium - pathology | Angiotensin II Type 1 Receptor Blockers - pharmacology | Energy Intake | Myosin Heavy Chains - metabolism | MAP Kinase Signaling System | Obesity - metabolism | Obesity - pathology | Ventricular Remodeling | Animals | Myocardium - metabolism | Receptor, Angiotensin, Type 1 - metabolism | Angiotensins - metabolism | Receptor, Insulin - metabolism | Type 2 diabetes | Obesity | Medical research | Triglycerides | Glucose | Muscle proteins | Dextrose | Cardiovascular agents | Diet | Leptin | Angiotensin | Myosin | Physiological aspects | Medicine, Experimental | Insulin resistance | Phosphotransferases | Transcription factors | Enzyme activity | Disorders | Kinases | Glucose metabolism | Enzymatic activity | Peptidyl-dipeptidase A | Rodents | Attenuation | Blood pressure | Lipid metabolism | Angiotensin II | Heart diseases | Echocardiography | Extracellular signal-regulated kinase | JNK protein | Metabolism | Insulin | 1-Phosphatidylinositol 3-kinase | Glucose tolerance | Fibrosis | In vivo methods and tests | Hypertrophy
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 16
Obesity is a pandemic associated with a high incidence of cardiovascular disease; however, the mechanisms are not fully elucidated. Proteomics may provide a... 
MYO1C | WESTERN DIET | MULTIDISCIPLINARY SCIENCES | FATTY-ACID-METABOLISM | GENE-EXPRESSION | CARDIAC DYSFUNCTION | MICE | TERM | PROTEINS | STRESS | FAILURE | Obesity | Echocardiography | Gel electrophoresis | Therapeutic applications | Mass spectroscopy | Fatty acids | Muscle contraction | Antioxidants | Ultrasonic imaging | Diet | Rodents | Proteomics | Cytoskeleton | Cardiovascular diseases
Journal Article
Journal Article
Cardiovascular Diabetology, ISSN 1475-2840, 10/2013, Volume 12, Issue 1, pp. 152 - 152
Background: The combination of systemic arterial hypertension and diabetes mellitus (DM) induces greater cardiac remodeling than either condition alone.... 
Oxidative stress | Spontaneously hypertensive rats | Systemic hypertension | Elderly | Diabetes mellitus | FIBROSIS | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | CARDIOMYOPATHY | MODEL | HYPERTROPHY | ENDOCRINOLOGY & METABOLISM | FOOD RESTRICTION | TYPE-1 | MYOCARDIAL DYSFUNCTION | EXPRESSION | Diabetic Cardiomyopathies - metabolism | Oxidative Stress - physiology | Diabetes Mellitus, Experimental - genetics | Transcriptome | Myosin Heavy Chains - genetics | Male | Hypertrophy, Left Ventricular - genetics | Atrial Natriuretic Factor - genetics | Myocardium - metabolism | Ventricular Remodeling - genetics | Diabetes Mellitus, Experimental - complications | Hypertension - genetics | Diabetes Mellitus, Experimental - metabolism | Rats, Inbred SHR | Diabetic Cardiomyopathies - diagnostic imaging | Echocardiography | Cardiac Myosins - genetics | Hydroxyproline - metabolism | Hypertrophy, Left Ventricular - metabolism | Oxidative Stress - genetics | Rats | Ventricular Remodeling - physiology | Reverse Transcriptase Polymerase Chain Reaction | Hypertension - metabolism | Diabetic Cardiomyopathies - genetics | Animals | Hypertension - complications | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Hypertrophy, Left Ventricular - diagnostic imaging | Studies | Hypertension | Heart failure | Medical research | Heart attacks | Mortality | Rodents
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, p. e0193553
Pathological cardiac hypertrophy leads to derangements in lipid metabolism that may contribute to the development of cardiac dysfunction. Since previous... 
OXIDATION | PRESSURE-OVERLOAD | OBESITY | DIET | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | DISEASE | RATS | IMPROVES | STRESS | ADIPOSE-TISSUE | Unsaturated fatty acids | Fatty acid metabolism | Heart enlargement | Physiological aspects | Genetic aspects | Research | Risk factors
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0138605
Obesity has been shown to impair myocardial performance. Some factors have been suggested as responsible for possible cardiac abnormalities in models of... 
RAT CARDIOMYOCYTES | PHOSPHOLAMBAN PHOSPHORYLATION | HIGH-FAT-DIET | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | CYCLASE ACTIVITY | CONTRACTILE RESPONSE | LEFT-VENTRICULAR MASS | SYSTOLIC FUNCTION | FAILING HEARTS | UP-REGULATION | GTP-Binding Protein alpha Subunits, Gs - metabolism | Heart - physiopathology | Adiposity - drug effects | Calcium - pharmacology | Rats, Wistar | Adrenergic beta-Agonists - pharmacology | Diet, High-Fat - adverse effects | Myocardial Contraction - drug effects | Male | Obesity - physiopathology | Blotting, Western | Obesity - metabolism | Papillary Muscles - physiopathology | Animals | Signal Transduction - drug effects | Time Factors | Isoproterenol - pharmacology | Heart - drug effects | Obesity - etiology | Papillary Muscles - metabolism | Blood Pressure - drug effects | Papillary Muscles - drug effects | Receptors, Adrenergic, beta - metabolism | Heart | Phosphorylation | Adipose tissue | Calcium | Impairment | Isoproterenol | Heart function | Kinases | Contraction | High fat diet | Proteins | Signal transduction | Receptors | Rodents | Blood pressure | Cardiology | Physical education | Heart diseases | Obesity | Carbohydrates | Cardiac muscle | Abnormalities | Muscles | Rats | Cardiomyocytes | Fatty acids | Medicine | Signaling | Diet | Diabetes | Laboratory animals | Calcium (extracellular) | Calcium ions
Journal Article
Journal Article
Journal Article
Arquivos Brasileiros de Cardiologia, ISSN 0066-782X, 11/2017, Volume 109, Issue 5, pp. 432 - 439
Background: Different types of high-fat and/or high-energy diets have been used to induce obesity in rodents. However, few studies have reported on the effects... 
Obesity | Hight-fat | Adiposity | Calcium | Diet | Cardiac function | Rats | SPRAGUE-DAWLEY RATS | LEPTIN | CARDIAC & CARDIOVASCULAR SYSTEMS | HIGH-FAT-DIET | CARBOHYDRATE | Hight-Fat | PATHWAY | RESISTANCE | HYPERTENSION | RODENT MODEL | Original | Ratos | Cálcio | Função cardíaca | Obesidade | Dieta Hiperlipídica | Adiposidade
Journal Article
Journal Article