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Cancer Cell, ISSN 1535-6108, 05/2015, Volume 27, Issue 5, pp. 609 - 611
In this issue of , Polprasert and colleagues identified recurrent mutations in the DEAD/H-box RNA helicase gene in familial and acquired cases of... 
ONCOLOGY | LEUKEMIA | CELL BIOLOGY | DEAD-box RNA Helicases - genetics | Animals | Humans | Germ-Line Mutation | Female | Male | Leukemia, Myeloid, Acute - genetics | Genetic aspects | RNA | Cells | Cancer | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2015, Volume 27, Issue 4, pp. 502 - 515
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2017, Volume 127, Issue 12, pp. 4297 - 4313
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 06/2017, Volume 21, Issue 6, pp. 1237 - 1242
Journal Article
Nature chemical biology, ISSN 1552-4450, 11/2015, Volume 11, Issue 11, pp. 878 - 886
Neomorphic mutations in isocitrate dehydrogenase 1 (IDH1) are driver mutations in acute myeloid leukemia (AML) and other cancers. We report the development of... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 07/2014, Volume 124, Issue 1, pp. 5 - 6
In this issue of Blood, Placke et al identify the cell-cycle regulator CDK6 as a promising new target in mixed lineage leukemia (MLL)-rearranged acute myeloid... 
HEMATOLOGY | INHIBITION | LEUKEMOGENESIS | Cyclin-Dependent Kinase 6 - metabolism | Animals | Myeloid-Lymphoid Leukemia Protein - genetics | Humans | Leukemia, Myeloid, Acute - metabolism | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2018, Volume 215, Issue 6, pp. 1709 - 1727
The surface molecule interleukin-1 receptor accessory protein (IL1RAP) is consistently overexpressed across multiple genetic subtypes of acute myeloid leukemia... 
MEDICINE, RESEARCH & EXPERIMENTAL | XENOGRAFT MODELS | RECEPTOR ACCESSORY PROTEIN | HEMATOPOIETIC STEM-CELLS | MAST-CELLS | ANALYSIS DEFINES | ACUTE MYELOID-LEUKEMIA | IL-1 RECEPTOR | IMMUNOLOGY | FLT3 LIGAND | NF-KAPPA-B | MYELODYSPLASTIC SYNDROMES | Apoptosis - drug effects | Humans | Leukemia, Myeloid, Acute - metabolism | Middle Aged | Male | Proto-Oncogene Proteins c-kit - metabolism | Carcinogenesis - metabolism | Hematopoiesis - drug effects | Interleukin-1 Receptor Accessory Protein - metabolism | Gene Deletion | Protein Binding - drug effects | Adult | Female | Membrane Proteins - metabolism | Stem Cell Factor - metabolism | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Down-Regulation - drug effects | Antibodies - pharmacology | Carcinogenesis - pathology | Animals | Cell Differentiation - drug effects | Models, Biological | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Tyrosine | Therapeutic applications | Myeloid leukemia | Pathogenesis | Leukemia | RNA-mediated interference | Interleukin | Antibodies | Interleukin 1 receptors | Kinases | Ribonucleic acid--RNA | c-Kit protein | Molecular chains | Hemopoiesis | Proteins | Signal transduction | Signaling | Clonal deletion | Stem cells | Interleukin 1 | Deletion | Acute myeloid leukemia | Viability | Index Medicus | 304
Journal Article
Blood, ISSN 0006-4971, 02/2015, Volume 125, Issue 6, pp. 930 - 940
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 11/2015, Volume 11, Issue 11, pp. 878 - 886
Neomorphic mutations in isocitrate dehydrogenase 1 (IDH1) are driver mutations in acute myeloid leukemia (AML) and other cancers. We report the development of... 
ISOCITRATE DEHYDROGENASE 1 | SELECTIVE-INHIBITION | PROGENITOR CELLS | DNA METHYLATION | SMALL-MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLINICAL-IMPLICATIONS | KINASE INHIBITORS | CELL-DIFFERENTIATION | MYELODYSPLASTIC SYNDROMES | ACUTE PROMYELOCYTIC LEUKEMIA | Neoplastic Stem Cells - drug effects | Allosteric Regulation | Humans | Crystallography, X-Ray | Male | Isocitrate Dehydrogenase - antagonists & inhibitors | Dose-Response Relationship, Drug | Leukemia, Myeloid, Acute - enzymology | Pyrazoles - chemistry | Enzyme Inhibitors - pharmacokinetics | Granulocytes - drug effects | Cytosine - metabolism | Dihydropyridines - pharmacokinetics | Enzyme Inhibitors - chemistry | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Granulocytes - pathology | Pyrazoles - pharmacokinetics | Pyrazoles - pharmacology | Dihydropyridines - chemistry | Leukemia, Myeloid, Acute - pathology | Enzyme Inhibitors - pharmacology | Models, Molecular | Isocitrate Dehydrogenase - genetics | Cytosine - chemistry | Granulocytes - enzymology | Xenograft Model Antitumor Assays | Animals | Cell Differentiation - drug effects | Isocitrate Dehydrogenase - chemistry | Allosteric Site | Cell Line, Tumor | CpG Islands | Dihydropyridines - pharmacology | Protein Binding | Isocitrate Dehydrogenase - metabolism | Mice | Kinetics | Mutation | Primary Cell Culture | DNA Methylation - drug effects | Neoplastic Stem Cells - enzymology | Leukemia, Myeloid, Acute - genetics | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 09/2012, Volume 120, Issue 13, pp. 2719 - 2722
RUNX1 gene alterations are associated with acquired and inherited hematologic malignancies that include familial platelet disorder/acute myeloid leukemia,... 
THROMBOCYTOPENIA | FREQUENT | MUTATIONS | HEMATOLOGY | BINDING | CHRONIC MYELOMONOCYTIC LEUKEMIA | Blood Platelets - pathology | Leukemia, Myelomonocytic, Chronic - diagnosis | Nonmuscle Myosin Type IIB - metabolism | Prognosis | Humans | Leukemia, Myeloid, Acute - metabolism | Leukemia, Myelomonocytic, Chronic - genetics | Myosin Heavy Chains - genetics | Immunoblotting | Male | Core Binding Factor Alpha 2 Subunit - physiology | Leukemia, Myelomonocytic, Chronic - metabolism | Myosin Heavy Chains - metabolism | Case-Control Studies | Jacobsen Distal 11q Deletion Syndrome - genetics | Thrombocytopenia - genetics | Proto-Oncogene Protein c-fli-1 - metabolism | Female | Biomarkers - metabolism | Blood Platelet Disorders - genetics | Genetic Predisposition to Disease | Proto-Oncogene Protein c-fli-1 - genetics | Nonmuscle Myosin Type IIB - genetics | Jacobsen Distal 11q Deletion Syndrome - metabolism | Blood Platelet Disorders - diagnosis | Thrombocytopenia - metabolism | Megakaryocytes - pathology | Animals | Leukemia, Myeloid, Acute - diagnosis | Comparative Genomic Hybridization | Blood Platelets - metabolism | Pedigree | Ploidies | Jacobsen Distal 11q Deletion Syndrome - diagnosis | Thrombocytopenia - diagnosis | Mice | Blood Platelet Disorders - metabolism | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
Journal Article