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Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 5/2018, Volume 36, Issue 5, pp. 775 - 784
Macrophages are crucial drivers of inflammatory corneal neovascularization and thus are potential targets for immunomodulatory therapies. We hypothesized that... 
Angiogenesis | Cornea | PEDF | Mesenchymal Stromal Cells | Inflammation | Macrophages | Pigment Epithelial Derived Factor
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e59965
The pathogenesis of acute lung injury (ALI) involves bidirectional cooperation and close interaction between inflammatory and coagulation pathways. A key... 
NEUTROPHIL ADHESION | VASCULAR INJURY | TISSUE-FACTOR | INTERCELLULAR-ADHESION MOLECULE-1 | ICAM-1 EXPRESSION | MULTIDISCIPLINARY SCIENCES | COAGULATION | ACTIN CYTOSKELETON | RELA/P65 NUCLEAR TRANSLOCATION | NF-KAPPA-B | RESPIRATORY-DISTRESS-SYNDROME | Human Umbilical Vein Endothelial Cells | Endothelial Cells - metabolism | Humans | Mice, Inbred C57BL | Gene Expression Regulation | Male | Mice, Transgenic | Inflammation | Myosin-Light-Chain Kinase - physiology | Intercellular Adhesion Molecule-1 - metabolism | Animals | Cell Nucleus - metabolism | Transcription Factor RelA - metabolism | Endothelial Cells - cytology | Blood Coagulation | Female | Leukocytes, Mononuclear - cytology | Lung - metabolism | Mice | Thrombin - metabolism | Neutrophils - metabolism | Peroxidase - metabolism | Thrombin | Muscle proteins | Lung diseases | Myosin | Endothelium | Pediatrics | Phosphorylation | Transcription factors | Transcription | Pathogenesis | Serine | Coagulation | Chains | Inflammatory response | Kinases | Myosin-light-chain kinase | Proteins | Rodents | Cooperation | Translocation | Edema | Immunoglobulins | Stability | Intercellular adhesion molecule 1 | Computational fluid dynamics | Neutrophils | Muscles | Permeability | Dentistry | Nuclear transport | Endothelial cells | Medicine | Respiratory distress syndrome | Lungs | Sepsis | Serine proteinase | Infiltration | RelA protein
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 05/2003, Volume 92, Issue 10, pp. 1089 - 1097
ABSTRACT—We tested the hypothesis that TNF-α induces early-onset endothelial adhesivity toward PMN by activating the constitutive endothelial cell surface... 
Polymorphonuclear leukocyte adhesion | Protein kinase Cζ | Tumor necrosis factor-α | Intercellular adhesion molecule-1 | Endothelium
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 10/2000, Volume 279, Issue 4, pp. 906 - 914
We addressed the role of protein kinase C (PKC) isozymes in mediating tumor necrosis factor-α (TNF-α)-induced oxidant generation in endothelial cells, a... 
Protein kinase C isoforms | Oxidants | Nuclear factor-κB | Intercellular adhesion molecule-1 | Endothelium
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 09/2002, Volume 91, Issue 5, pp. 398 - 405
ABSTRACT—As thrombin binding to the G protein–coupled proteinase activated receptor-1 (PAR-1) induces endothelial adhesivity to leukocytes through NF-κB... 
Akt | G proteins | Protein kinase C-δ | Nuclear factor-κB | Intercellular adhesion molecule-1
Journal Article
Journal of Parenteral and Enteral Nutrition, ISSN 0148-6071, 05/2003, Volume 27, Issue 3, pp. 176 - 181
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 04/2005, Volume 288, Issue 4, pp. 655 - 662
Journal Article
American Journal of Physiology, ISSN 1040-0605, 04/2005, Volume 32, Issue 4, p. L655
  We identify herein a novel signaling function of the Toll-like receptor-4 (TLR4), the lipopolysaccharide (LPS) receptor mediating the innate immune response,... 
Leucocytes | Respiratory system | Cell adhesion & migration
Journal Article
American Journal of Physiology, ISSN 1040-0605, 11/2004, Volume 31, Issue 5, p. L1017
  We investigated the mechanisms by which elevated intracellular cAMP concentration inhibits the thrombin-induced ICAM-1 expression in endothelial cells.... 
Proteins | Circulatory system | Respiratory system | Cells
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2004, Volume 173, Issue 11, pp. 6965 - 6972
We investigated the involvement of the RhoA/Rho-associated kinase (ROCK) pathway in regulating ICAM-1 expression in endothelial cells by the procoagulant,... 
Journal Article
Journal of Parenteral and Enteral Nutrition, ISSN 0148-6071, 07/2004, Volume 28, Issue 4, pp. 232 - 240
Journal Article
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN 1040-0605, 04/2005, Volume 288, Issue 4, pp. L655 - L662
We identify herein a novel signaling function of the Toll-like receptor-4 (TLR4), the lipopolysaccharide (LPS) receptor mediating the innate immune response,... 
Journal Article
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