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Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2015, Volume 463, Issue 1-2, pp. 154 - 160
Lysine ε-aminotransferase (LAT) converts lysine to α-aminoadipate-δ-semialdehyde in a PLP-mediated reaction. We mutated active-site T330, N328 and E243, and... 
Glu243 switch | Lysine ε-aminotransferase | Mycobacterium tuberculosis | 2-Aminomethyl piperidine derivative | α-ketoglutarate | Crystal structure | ACID | alpha-ketoglutarate | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | GRAPHICS | RV3290C | BIOPHYSICS | Lysine epsilon-aminotransferase | ENZYMES
Journal Article
Journal Article
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 09/2016, Volume 73, Issue 17, pp. 3401 - 3417
Mycobacterium tuberculosis codes for a HAD-phosphatase, Rv3042c (MtSerB2), that has earlier been characterized as a metabolic enzyme. Here we demonstrate that... 
MAPK p38 | Clofazimine | Mycobacterium tuberculosis | Phosphoserine phosphatase | Actin dynamics | Secretory protein | Drug target | Riminophenazine | Immune evasion | MYCOBACTERIUM-TUBERCULOSIS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | TYROSINE-PHOSPHATASE | COFILIN | CELL BIOLOGY | BACTERIAL PATHOGENS | PORPHYROMONAS-GINGIVALIS SERB | NF-KAPPA-B | CELL | Humans | Actins - metabolism | Bacterial Proteins - chemistry | Tuberculosis - microbiology | Recombinant Proteins - biosynthesis | Mycobacterium tuberculosis - drug effects | Tuberculosis - diagnosis | Recombinant Proteins - isolation & purification | Actin Cytoskeleton - drug effects | Protein Structure, Quaternary | Bronchoalveolar Lavage Fluid - cytology | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | Binding Sites | Dimerization | Mycobacterium tuberculosis - metabolism | Macrophages - microbiology | Cell Line | Phosphoric Monoester Hydrolases - genetics | Heat-Shock Proteins - metabolism | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Macrophages - cytology | Down-Regulation - drug effects | Tuberculosis - immunology | Macrophages - metabolism | Transcription Factor RelA - metabolism | Bacterial Proteins - metabolism | Molecular Docking Simulation | Bronchoalveolar Lavage Fluid - chemistry | Phosphoric Monoester Hydrolases - metabolism | Heat-Shock Proteins - chemistry | Phosphoric Monoester Hydrolases - chemistry | Enzymes | Tuberculosis | Phosphatases | Interleukins | Actin | Heat shock proteins | Research institutes | Pharmaceutical industry | Muscle proteins | Inflammation | Phosphatase | Immune system
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2015, Volume 463, Issue 1-2, pp. 154 - 160
Lysine -aminotransferase (LAT) converts lysine to alpha -aminoadipate- delta -semialdehyde in a PLP-mediated reaction. We mutated active-site T330, N328 and... 
Journal Article
Indian Journal of Dermatology, Venereology and Leprology, ISSN 0378-6323, 05/2018, Volume 84, Issue 3, pp. 328 - 331
{Table 2}{Table 3}{Figure 1} Thirty eight patients (63.3%) had features of atypical hand, foot and mouth disease [Table 1], [Table 2], [Table 3] and [Figure... 
OUTBREAK | COXSACKIEVIRUS A6 | DERMATOLOGY | Laboratories | Dermatology | Viruses | Infections | Patients | Epidemiology | Virology | Polymerase chain reaction | Higher education | Consent | Influenza | Guardians | Viral infections
Journal Article
The Journal of the Association of Physicians of India, ISSN 0004-5772, 01/2016, Volume 64, Issue 1, p. 118
Journal Article
The Journal of the Association of Physicians of India, ISSN 0004-5772, 01/2016, Volume 64, Issue 1, p. 48
Journal Article
Cardiovascular Toxicology, ISSN 1530-7905, 4/2017, Volume 17, Issue 2, pp. 175 - 184
Journal Article
IEEE Journal of Solid-State Circuits, ISSN 0018-9200, 01/2008, Volume 43, Issue 1, pp. 6 - 20
Journal Article
Indian Journal of Medical Research, ISSN 0971-5916, 2019, Volume 150, Issue 3, pp. 282 - 289
Background & objectives: Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder and is caused mainly by deletion, duplication and point mutations... 
Studies | Proteins | Sample size | Scoliosis | Genes | Mutation | Kinases | Patients | Deoxyribonucleic acid--DNA | deletions - duchenne muscular dystrophy - multiplex ligation-dependent probe amplification - next-generation sequencing - partial deletion - single-nucleotide variation
Journal Article
eLife, ISSN 2050-084X, 12/2018, Volume 7
Journal Article