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1. Full Text n−3 Fatty Acids in Patients with Multiple Cardiovascular Risk Factors
by Roncaglioni, Maria Carla and Avanzini, Fausto and Barlera, Simona and Marzona, Irene and Milani, Valentina and Tombesi, Massimo and Caimi, Vittorio and Longoni, Paolo and Silletta, Maria Giuseppina and Tognoni, Gianni and Marchioli, Roberto and Nicolis, E.B and Casola, C and Massa, E and Marrocco, W and Micalella, M and Franzosi, M.G and Geraci, E and Giansiracusa, N and Rocchetti, L and Decarli, A and Satolli, R and Alli, C and Beghi, E and Bertele', V and Volpi, A and Baviera, M and Monesi, L and Pangrazzi, I and Nicolis, E and Clerici, F and Palumbo, A and Sgaroni, G and Pioggiarella, R and Scarano, M and Marfisi, R.M and Flamminio, A and Macino, L and Ferri, B and Pera, C and Polidoro, A and Abbatino, D and Acquati, M and Addorisio, G and Adinolfi, D and Adreani, L and Agistri, M.R and Agneta, A and Agnolio, M.L and Agostini, N and Agostino, G and Airò, A and Alaimo, N and Albano, M and Albano, N and Alecci, G and Alemanno, S and Alexanian, A and Alfarano, M and Alfè, L and Alonzo, N and Alvino, S and Ancora, A and Andiloro, S and Andreatta, E and Angeli, S and Angiari, F and Angilletti, V and Annicchiarico, C and Anzivino, M and Aprea, R and Aprile, A and Aprile, E and Aprile, I and Aprile, L and Armellani, V and Arnetoli, M and Aronica, A and Autiero, V and Bacca, G and Baccalaro, A.M and Bacci, M and Baglio, G and Bagnani, M and Baiano, A and Baldari, A and Ballarini, L and Banchi, G and Bandera, R and Bandini, F and Baratella, M and Barbieri, A and Barbieri Vita, A and Bardi, M and Barlocchi, M and Baron, P and Bartoli, M and Basile, A and Basile, F and Basile, S and ... and The Risk and Prevention Study Collaborative Group and Risk Prevention Study Collaborativ and Risk and Prevention Study Collaborative Group
The New England Journal of Medicine, ISSN 0028-4793, 05/2013, Volume 368, Issue 19, pp. 1800 - 1808
In a randomized trial, patients with cardiovascular risk factors but no history of myocardial infarction were assigned to receive n−3 fatty acids or placebo.... 
MEDICINE, GENERAL & INTERNAL | Primary Prevention | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Hospitalization | Treatment Failure | General Practice | Cardiovascular Diseases - mortality | Fatty Acids, Omega-3 - therapeutic use | Female | Aged | Fatty Acids, Omega-3 - adverse effects | Prevention | Complications and side effects | Cardiovascular diseases | Health aspects | Risk factors | Omega-3 fatty acids | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | Polyunsaturated fatty acids | Mortality | Clinical trials | Cardiovascular disease | Olive oil | Angina pectoris | Patients | Fatty acids | Morbidity | Disease prevention | Vascular diseases | Arteriosclerosis | Patient safety | Heart diseases
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2. AVATARÂŽ: An electronic evidence-based medicine friendly tool for vascular access planning
by Faraone, Vincenzo and Aprea, Pasquale and Spencer, Timothy R
Minerva Medica, ISSN 0026-4806, 08/2018, Volume 109, Issue 4, pp. 326 - 333
In today's demanding healthcare setting, many patients who are referred to hospital for treatment require some form of intravascular access device to... 
Computer-assisted decision making | Software | Planning techniques | Vascular surgical procedures | POWER INJECTION | MEDICINE, GENERAL & INTERNAL
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3. Full Text The coffee genome provides insight into the convergent evolution of caffeine biosynthesis
by Denoeud, France and Carretero-Paulet, Lorenzo and Carretero-Paulet, Lorenzo and Dereeper, Alexis and Dereeper, Alexis and Droc, GaÍtan and Droc, GaÍtan and Guyot, Romain and Guyot, Romain and Pietrella, Marco and Pietrella, Marco and Zheng, Chunfang and Alberti, Adriana and Anthony, François and Anthony, François and Aprea, Giuseppe and Aprea, Giuseppe and Aury, Jean-Marc and Bento, Pascal and Bernard, Maria and Bocs, StÊphanie and Bocs, StÊphanie and Campa, Claudine and Campa, Claudine and Cenci, Alberto and Cenci, Alberto and Combes, Marie-Christine and Combes, Marie-Christine and Crouzillat, Dominique and Da Silva, Corinne and Daddiego, Loretta and De Bellis, Fabien and De Bellis, Fabien and Dussert, StÊphane and Dussert, StÊphane and Garsmeur, Olivier and Garsmeur, Olivier and Gayraud, Thomas and Gayraud, Thomas and Guignon, Valentin and Guignon, Valentin and Jahn, Katharina and Jahn, Katharina and Jamilloux, VÊronique and JoÍt, Thierry and JoÍt, Thierry and Labadie, Karine and Lan, Tianying and Lan, Tianying and Leclercq, Julie and Leclercq, Julie and Lepelley, Maud and Leroy, Thierry and Leroy, Thierry and Li, Lei-Ting and Li, Lei-Ting and Librado, Pablo and Librado, Pablo and Lopez, Loredana and Muùoz, Adriana and Muùoz, Adriana and Noel, Benjamin and Pallavicini, Alberto and Perrotta, Gaetano and Perrotta, Gaetano and Poncet, ValÊrie and Poncet, ValÊrie and Pot, David and Pot, David and Priyono, Priyono and Priyono, P and Rigoreau, Michel and Rouard, Mathieu and Rouard, Mathieu and Rozas, Julio and Rozas, Julio and Tranchant-Dubreuil, Christine and Tranchant-Dubreuil, Christine and VanBuren, Robert and Zhang, Qiong and Zhang, Qiong and Andrade, Alan C and Andrade, Alan C and Argout, Xavier and Argout, Xavier and Bertrand, BenoÎt and De Kochko, Alexandre and De Kochko, Alexandre and Graziosi, Giorgio and Henry, Robert J and Jayarama, J and Jayarama, Jayarama and Ming, Ray and Nagai, Chifumi and Nagai, Chifumi and Rounsley, Steve and Sankoff, David and Giuliano, Giovanni and Giuliano, Giovanni and Albert, Victor A and ...
Science, ISSN 0036-8075, 09/2014, Volume 345, Issue 6201, pp. 1181 - 1184
Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome... 
ARABICA | SEEDS | PATHWAY | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | GENE CLUSTERS | PLANTS | HORIZONTAL TRANSFERS | FAMILY | Plant Proteins - genetics | Coffea - genetics | Methyltransferases - physiology | Caffeine - biosynthesis | Plant Proteins - physiology | Methyltransferases - genetics | Caffeine - genetics | Coffea - classification | Genome, Plant | Phylogeny | Evolution, Molecular | Biosynthesis | Genetic aspects | Properties | Caffeine | Evolution | Genomes | Coffee | Tea | Reproduction | Genes | Chocolate
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4. Full Text Rational design of small molecules as vaccine adjuvants
by Wu, Tom Y.-H and Singh, Manmohan and Miller, Andrew T and De Gregorio, Ennio and Doro, Francesco and D'Oro, Ugo and Skibinski, David A. G and Mbow, M. Lamine and Bufali, Simone and Herman, Ann E and Cortez, Alex and Li, Yongkai and Nayak, Bishnu P and Tritto, Elaine and Filippi, Christophe M and Otten, Gillis R and Brito, Luis A and Monaci, Elisabetta and Li, Chun and Aprea, Susanna and Valentini, Sara and Calabro, Samuele and Laera, Donatello and Brunelli, Brunella and Caproni, Elena and Malyala, Padma and Panchal, Rekha G and Warren, Travis K and Bavari, Sina and O'Hagan, Derek T and Cooke, Michael P and Valiante, Nicholas M
Science Translational Medicine, ISSN 1946-6234, 11/2014, Volume 6, Issue 263, pp. 263ra160 - 263ra160
Adjuvants increase vaccine potency largely by activating innate immunity and promoting inflammation. Limiting the side effects of this inflammation is a major... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNIZATION | ASSAY | NEISSERIA-MENINGITIDIS | SEROGROUP-B MENINGOCOCCUS | INFECTION | CANDIDATES | IDENTIFICATION | AGONISTS | DISCOVERY | RESIQUIMOD | CELL BIOLOGY | Adjuvants, Immunologic - pharmacokinetics | Biological Availability | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Vaccines - administration & dosage | Drug Design
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5. Full Text Efficacy of n-3 polyunsaturated fatty acids and feasibility of optimizing preventive strategies in patients at high cardiovascular risk: Rationale, design and baseline characteristics of the Rischio and Prevenzione study, a large randomised trial in general practice
by Avanzini, F and Barlera, S and Caimi, V and Longoni, P and Marchioli, R and Roncaglioni, MC and Silletta, MG and Tognoni, G and Tombesi, M and Massa, E and Marrocco, W and Micalella, M and Aprile, L and Franzosi, MG and Geraci, E and Giansiracusa, N and Rocchetti, L and Decarli, A and Satolli, R and Alli, C and Beghi, E and Volpi, VBA and Monesi, L and Marzona, I and Baviera, M and Milani, V and Nicolis, E and Casola, C and Clerici, F and Palumbo, A and Sgaroni, G and Pioggiarella, R and Scarano, M and Marfisi, RM and Flamminio, A and Mancino, L and Ferri, B and Pera, C and Polidoro, A and Abbatino, D and Acquati, M and Addorisio, G and Adinolfi, D and Adreani, L and Agistri, MR and Agneta, A and Agnolio, ML and Agostini, N and Agostino, G and Airo, A and Alaimo, N and Albano, M and Albano, N and Alecci, G and Alemanno, S and Alexanian, A and Alfarano, M and Alfe, L and Alonzo, N and Alvino, S and Ancora, A and Andiloro, S and Andreatta, E and Angeli, S and Angiari, F and Angilletti, V and Annicchiarico, C and Anzivino, M and Aprea, R and Aprile, A and Aprile, E and Aprile, I and Armellani, V and Arnetoli, M and Aronica, A and Autiero, V and Bacca, G and Baccalaro, AM and Bacci, M and Baglio, G and Bagnani, M and Baiano, A and Baldari, A and Ballarini, L and Banchi, G and Bandera, R and Bandini, F and Baratella, M and Barbieri, A and Vita, AB and Bardi, M and Barlocchi, M and Baron, P and Bartoli, M and Basile, A and Basile, F and Basile, S and Battaggia, A and Battaglia, A and Bau, A and ... and Rischio Prevenzione Investigators and Rischio and Prevenzione Investigators
Trials, ISSN 1745-6215, 05/2010, Volume 11, Issue 1, pp. 68 - 68
Background: The optimization of preventive strategies in patients at high risk of cardiovascular events and the evaluation of bottlenecks and limitations of... 
MORTALITY | MEDICINE, RESEARCH & EXPERIMENTAL | VITAMIN-E | FISH CONSUMPTION | PRIMARY-CARE | MYOCARDIAL-INFARCTION | TASK-FORCE | EUROPEAN COUNTRIES | SUDDEN-DEATH | CORONARY-HEART-DISEASE | SECONDARY PREVENTION | Follow-Up Studies | Cardiovascular Diseases - drug therapy | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Risk Factors | Male | Feasibility Studies | Cardiotonic Agents - therapeutic use | Family Practice | Diabetes Mellitus - epidemiology | Cardiovascular Diseases - epidemiology | Fatty Acids, Omega-3 - therapeutic use | Female | Italy - epidemiology | Aged | Prevention | Unsaturated fatty acids | Complications and side effects | Care and treatment | Prognosis | Cardiovascular diseases | Health aspects | Heart attack | Risk factors
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6. Full Text Effect of 5% transdermal lidocaine patches on postoperative analgesia in dogs undergoing hemilaminectomy
by Re Bravo, V and Aprea, F and Bhalla, R. J and De Gennaro, C and Cherubini, G. B and Corletto, F and Vettorato, E
Journal of Small Animal Practice, ISSN 0022-4510, 03/2019, Volume 60, Issue 3, pp. 161 - 166
Objectives To investigate the effect of 5% lidocaine patches on postoperative analgesia in dogs undergoing hemilaminectomy. Materials and Methods Client‐owned... 
SURGERY | TOPICAL LIDOCAINE | NEUROPATHIC PAIN | PHARMACOKINETICS | POSTHERPETIC NEURALGIA | MEDICATED PLASTER | VETERINARY SCIENCES | ABSORPTION | Methadone hydrochloride | Analgesia | Gabapentin | Diazepam | Transdermal medication | Dogs | Pain perception | Fentanyl | Inflammation | Methadone | Isoflurane | Pain | Surgery | Anesthesia | Skin | Propofol | Lidocaine
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