X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (25) 25
humans (12) 12
biochemistry & molecular biology (11) 11
animals (10) 10
protein binding (9) 9
electricity (8) 8
mice (8) 8
binding sites (7) 7
models, molecular (7) 7
binding (6) 6
biophysics (6) 6
blasting (6) 6
circuit arrangements or systems for supplying or distributingelectric power (6) 6
climate change mitigation technologies related totransportation (6) 6
combustion engines (6) 6
computer simulation (6) 6
conversion or distribution of electric power (6) 6
crystal-structure (6) 6
general tagging of cross-sectional technologies spanning over several sections of the ipc (6) 6
general tagging of new technological developments (6) 6
generation (6) 6
heating (6) 6
hot-gas or combustion-product engine plants (6) 6
lighting (6) 6
mechanical engineering (6) 6
starting aids for such engines, not otherwise providedfor (6) 6
starting of combustion engines (6) 6
systems for storing electric energy (6) 6
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (6) 6
technologies or applications for mitigation or adaptation againstclimate change (6) 6
weapons (6) 6
activation (5) 5
conformational dynamics (5) 5
crystal structure (5) 5
gas turbine (5) 5
male (5) 5
molecular dynamics simulation (5) 5
protein structure, tertiary (5) 5
structural basis (5) 5
drug discovery (4) 4
energy storage (4) 4
guanosine triphosphate - chemistry (4) 4
liquid air (4) 4
multidisciplinary sciences (4) 4
oncogene (4) 4
physics (4) 4
protein (4) 4
protein conformation (4) 4
protein structure, secondary (4) 4
proto-oncogene proteins p21 - chemistry (4) 4
ras (4) 4
signal transduction (4) 4
activating protein (3) 3
amino acid sequence (3) 3
base sequence (3) 3
chemotherapy (3) 3
cool storage unit (3) 3
docking (3) 3
female (3) 3
g proteins (3) 3
hydrolysis (3) 3
in situ hybridization (3) 3
inhibitors (3) 3
investigating or analysing materials by determining theirchemical or physical properties (3) 3
kinases (3) 3
light (3) 3
measuring (3) 3
mice, inbred c57bl (3) 3
middle aged (3) 3
molecular dynamics (3) 3
molecular sequence data (3) 3
molecular-dynamics (3) 3
monomeric gtp-binding proteins - metabolism (3) 3
mutation (3) 3
mutation, missense (3) 3
neurosciences (3) 3
nmr-spectroscopy (3) 3
nuclear magnetic resonance, biomolecular (3) 3
numerical simulation (3) 3
p21 (3) 3
peptides (3) 3
proteins (3) 3
proto-oncogene proteins p21 - metabolism (3) 3
research (3) 3
stability (3) 3
testing (3) 3
thermodynamics (3) 3
acyclic or carbocyclic compounds (2) 2
adult (2) 2
afatinib (2) 2
alzheimer's disease (2) 2
amyloid beta-peptides - metabolism (2) 2
antimitotic agents (2) 2
antineoplastic agents (2) 2
article (2) 2
basic electric elements (2) 2
binding proteins (2) 2
biological sciences (2) 2
cancer (2) 2
cell line, tumor (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, pp. 14768 - 14768
Osimertinib has been demonstrated to overcome the epidermal growth factor receptor (EGFR)-T790M, the most relevant acquired resistance to first-generation... 
1ST-LINE TREATMENT | GEFITINIB | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | OPEN-LABEL | INHIBITORS | MUTATIONS | AFATINIB | CHEMOTHERAPY | AZD9291 | ERLOTINIB | Index Medicus
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, pp. 340A - 340A
Conference Proceeding
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 20, pp. 8182 - 8187
Journal Article
Journal of Chemical Theory and Computation, ISSN 1549-9618, 06/2017, Volume 13, Issue 6, pp. 2389 - 2399
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 56a - 56a
Journal Article
Journal Article
Journal Article
Bioinformatics, ISSN 1367-4803, 03/2018, Volume 34, Issue 5, pp. 770 - 778
Abstract Motivation Fast and accurate prediction of protein-ligand binding structures is indispensable for structure-based drug design and accurate estimation... 
MOLECULAR-DYNAMICS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PERFORMANCE | STABILITY | DRUG DISCOVERY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Index Medicus | Original Papers
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2019, Volume 116, Issue 20, pp. 10025 - 10030
Journal Article
Journal of Physical Chemistry B, ISSN 1520-6106, 03/2019, Volume 123, Issue 11, pp. 2479 - 2490
A medium-sized and highly flexible inhibitor to the enzyme beta-secretase 1 (BACE), which produces the amyloid beta-peptide by cleavage of its precursor... 
BETA-HAIRPIN | PROTEIN | FORCE | FREE-ENERGY LANDSCAPE | APP CLEAVING ENZYME | CHEMISTRY, PHYSICAL | COMPLEX STRUCTURE | BINDING | PEPTIDE | STRUCTURE-BASED DESIGN | FLEXIBLE DOCKING
Journal Article
Molecular Brain, ISSN 1756-6606, 12/2018, Volume 11, Issue 1, pp. 1 - 13
Abstract The deposition of Amyloid-beta peptides (Aβ) is detected at an earlier stage in Alzheimer’s disease (AD) pathology. Thus, the approach toward Aβ... 
Journal Article
Biochemistry, ISSN 0006-2960, 09/2018, Volume 57, Issue 36, pp. 5350 - 5358
The ras oncogene products (H-Ras, K-Ras, and N-Ras) have been regarded as some of the most promising targets for anticancer drug discovery because their... 
TRIPHOSPHATE CONFORMATION | ACTIVATION | K-RAS | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | CONFORMATIONAL DYNAMICS | LIGAND | EFFECTOR INTERACTION | BINDING | Index Medicus
Journal Article
Breast Cancer, ISSN 1340-6868, 7/2016, Volume 23, Issue 4, pp. 617 - 623
Journal Article
Folia Pharmacologica Japonica, ISSN 0015-5691, 2017, Volume 149, Issue 6, pp. 281 - 287
Journal Article
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, ISSN 0015-5691, 2017, Volume 149, Issue 6, p. 281
Journal Article