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Cancer, ISSN 0008-543X, 01/2018, Volume 124, Issue 1, pp. 105 - 109
BACKGROUND In a phase 1 study of pulse/continuous‐dose erlotinib, no patient had disease progression in the central nervous system (CNS). This expansion cohort... 
non–small cell lung cancer | epidermal growth factor receptor (EGFR) | EGFR T790M | brain metastases | erlotinib | non-small cell lung cancer | PHASE-II TRIAL | GEFITINIB | ONCOLOGY | ADENOCARCINOMA | AFATINIB | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Response Evaluation Criteria in Solid Tumors | Brain Neoplasms - secondary | Aged, 80 and over | Female | Adenocarcinoma - genetics | Brain Neoplasms - radiotherapy | Cranial Irradiation - statistics & numerical data | Adenocarcinoma - radiotherapy | Lung Neoplasms - genetics | Erlotinib Hydrochloride - administration & dosage | Brain Neoplasms - genetics | Treatment Outcome | Tumor Burden | Brain Neoplasms - drug therapy | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Aged | Mutation | Brain | Toxicity | Exanthema | Lung cancer | Central nervous system | Radiation | Control systems | Nervous system | Metastasis | Dosage | Metastases | Confidence intervals | Epidermal growth factor | Quality | Lesions | Protein-tyrosine kinase | Tyrosine | Alanine | Epidermal growth factor receptors | Diarrhea | Fatigue | Nausea | Patients | Survival | Lungs | Response rates | Alanine transaminase | Solid tumors | Tumors | Cancer
Journal Article
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, ISSN 0098-7484, 08/2019, Volume 322, Issue 8, pp. 764 - 774
Journal Article
Cancer, ISSN 0008-543X, 06/2018, Volume 124, Issue 11, pp. 2272 - 2275
Progress in the rational development of therapy for patients with epidermal growth factor receptor‐mutant lung cancer depends on pursuing multiple parallel... 
GEFITINIB | OSIMERTINIB | INHIBITION | ONCOLOGY | BEVACIZUMAB | ACQUIRED-RESISTANCE | INITIAL TREATMENT | MUTATIONS | EMERGENCE | ERLOTINIB | AZD9291 | Medical care | Care and treatment | Lung cancer | Innovations | Therapy | Epidermal growth factor | Patients | Cancer therapies | Cancer
Journal Article
Cancer, ISSN 0008-543X, 06/2018, Volume 124, Issue 11, pp. 2272 - 2275
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182665
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2018, Volume 24, Issue 2, pp. 334 - 340
Purpose: KRAS mutations occur in approximately 25% of patients with non-small cell lung cancer (NSCLC). Despite the uniform presence of KRAS mutations,... 
ADJUVANT CHEMOTHERAPY | IMPACT | MUTATION STATUS | MECHANISM | NRF2 | ONCOLOGY | ADENOCARCINOMA | 4 TRIALS | POOLED ANALYSIS | EGFR MUTATION | DOCETAXEL | Adenocarcinoma | p53 Protein | Lung cancer | Non-small cell lung carcinoma | Multivariate analysis | Survival | Patients | Confidence intervals | Alterations | Chemotherapy | Immune checkpoint | Lungs | Experimental design | Platinum | Mutation | Cancer
Journal Article
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2019, Volume 37, Issue 4, pp. 278 - 285
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 12/2019, Volume 37, Issue 36, pp. 3546 - 3546
PURPOSE Response to programmed cell death protein 1 (PD-1) blockade is often conceptualized as resulting from reinvigoration of tumor-infiltrating lymphocytes.... 
IMMUNITY | PEMBROLIZUMAB | DENDRITIC CELLS | ONCOLOGY | TOLERANCE | INDUCTION | SINUSOIDAL-ENDOTHELIAL-CELLS | TUMORS | T-CELLS
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 35, Issue 4_suppl, pp. 458 - 458
458 Background: FOLFIRINOX is an active regimen for metastatic pancreatic cancer demonstrating a median overall survival of 11.1 months at the expense of... 
Journal Article
Evolution, ISSN 0014-3820, 08/2019, Volume 73, Issue 8, pp. 1591 - 1603
Neomorphic, membrane‐associated skeletal rods are found in disparate vertebrate lineages, but their evolution is poorly understood. Here we show that one of... 
flight | neomorphism | morphology | early burst | Chiroptera | evolutionary novelty | REGRESSION | FORAGING BEHAVIOR | MEMBRANE | FISHING BATS | RADIATION | EVOLUTIONARY BIOLOGY | EVOLUTION | GENETICS & HEREDITY | PHYLOGENETIC SIGNAL | UROPATAGIUM | ECOLOGY | HOMOLOGY | EARLY BURSTS | Bats | Flight | Interspecific | Rods | Phylogeny | Diversification | Vertebrates | Forearm | Mechanical loading | Tibia | Calcaneus | Evolution | Synovial joints | Novelty
Journal Article
INTEGRATIVE AND COMPARATIVE BIOLOGY, ISSN 1540-7063, 09/2019, Volume 59, Issue 3, pp. 656 - 668
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 02/2020
Treatment with PD-(L)1 blockade can produce remarkably durable responses in non-small cell lung cancer (NSCLC) patients. However, a significant fraction of... 
Journal Article