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2007, ISBN 9780226313375, 433
Long ago, fish fins evolved into the limbs of land vertebrates and tetrapods. During this transition, some elements of the fin were carried over while new... 
Biology, life sciences | Extremities (Anatomy) | Evolution
Book
Marine Mammal Science, ISSN 0824-0469, 10/2018, Volume 34, Issue 4, pp. 1134 - 1140
Journal Article
Marine Mammal Science, ISSN 0824-0469, 10/2018, Volume 34, Issue 4, pp. 1134 - 1140
Journal Article
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | Index Medicus | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
by Fitzgerald, T.W and Gerety, S.S and Jones, W.D and Van Kogelenberg, M and King, D.A and McRae, J and Morley, K.I and Parthiban, V and Al-Turki, S and Ambridge, K and Barrett, D.M and Bayzetinova, T and Clayton, S and Coomber, E.L and Gribble, S and Jones, P and Krishnappa, N and Mason, L.E and Middleton, A and Miller, R and Prigmore, E and Rajan, D and Sifrim, A and Tivey, A.R and Ahmed, M and Akawi, N and Andrews, R and Anjum, U and Archer, H and Armstrong, R and Balasubramanian, M and Banerjee, R and Baralle, D and Batstone, P and Baty, D and Bennett, C and Berg, J and Bernhard, B and Bevan, A.P and Blair, E and Blyth, M and Bohanna, D and Bourdon, L and Bourn, D and Brady, A and Bragin, E and Brewer, C and Brueton, L and Brunstrom, K and Bumpstead, S.J and Bunyan, D.J and Burn, J and Burton, J and Canham, N and Castle, B and Chandler, K and Clasper, S and Clayton-Smith, J and Cole, T and Collins, A and Collinson, M.N and Connell, F and Cooper, N and Cox, H and Cresswell, L and Cross, G and Crow, Y and D'Alessandro, M and Dabir, T and Davidson, R and Davies, S and Dean, J and Deshpande, C and Devlin, G and Dixit, A and Dominiczak, A and Donnelly, C and Donnelly, D and Douglas, A and Duncan, A and Eason, J and Edkins, S and Ellard, S and Ellis, P and Elmslie, F and Evans, K and Everest, S and Fendick, T and Fisher, R and Flinter, F and Foulds, N and Fryer, A and Fu, B and Gardiner, C and Gaunt, L and Ghali, N and Gibbons, R and Gomes Pereira, S.L and Goodship, J and Goudie, D and ... and Deciphering Dev Disorders Study and Deciphering Developmental Disorders Study and The Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7542, pp. 223 - 228
Despite three decades of successful, predominantly phenotype-driven discovery of the genetic causes of monogenic disorders(1), up to half of children with... 
INTELLECTUAL DISABILITY | HUMAN-DISEASE | DE-NOVO MUTATIONS | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | MODEL | AUTISM SPECTRUM DISORDERS | COPY-NUMBER VARIATION | CHILDREN | Rare Diseases - genetics | Humans | Parents | Child, Preschool | Infant | Male | Developmental Disabilities - genetics | Dynamin I - genetics | Mutation, Missense - genetics | Polycomb Repressive Complex 1 - genetics | Gene Expression Regulation, Developmental | Transposases - genetics | Female | Nuclear Proteins - genetics | Child | Developmental Disabilities - diagnosis | Infant, Newborn | Guanine Nucleotide Exchange Factors - genetics | Protein Phosphatase 2 - genetics | Protein-Serine-Threonine Kinases - genetics | United Kingdom | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Zebrafish - genetics | Chromosomal Proteins, Non-Histone - genetics | Carrier Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Animals | Adolescent | Chromosome Aberrations | Genes, Dominant - genetics | Usage | Genomics | Child development deviations | Genetic aspects | Research | Risk factors | Developmental disabilities | Studies | Hypotheses | Genes | Developmental psychology | Families & family life | Genomes | Mutation | Children & youth | Index Medicus
Journal Article
by Théry, Clotilde and Witwer, Kenneth W and Aikawa, Elena and Alcaraz, Maria Jose and Anderson, Johnathon D and Andriantsitohaina, Ramaroson and Antoniou, Anna and Arab, Tanina and Archer, Fabienne and Atkin-Smith, Georgia K and Ayre, D Craig and Bach, Jean-Marie and Bachurski, Daniel and Baharvand, Hossein and Balaj, Leonora and Baldacchino, Shawn and Bauer, Natalie N and Baxter, Amy A and Bebawy, Mary and Beckham, Carla and Bedina Zavec, Apolonija and Benmoussa, Abderrahim and Berardi, Anna C and Bergese, Paolo and Bielska, Ewa and Blenkiron, Cherie and Bobis-Wozowicz, Sylwia and Boilard, Eric and Boireau, Wilfrid and Bongiovanni, Antonella and Borràs, Francesc E and Bosch, Steffi and Boulanger, Chantal M and Breakefield, Xandra and Breglio, Andrew M and Brennan, Meadhbh Á and Brigstock, David R and Brisson, Alain and Broekman, Marike LD and Bromberg, Jacqueline F and Bryl-Górecka, Paulina and Buch, Shilpa and Buck, Amy H and Burger, Dylan and Busatto, Sara and Buschmann, Dominik and Bussolati, Benedetta and Buzás, Edit I and Byrd, James Bryan and Camussi, Giovanni and Carter, David RF and Caruso, Sarah and Chamley, Lawrence W and Chang, Yu-Ting and Chen, Chihchen and Chen, Shuai and Cheng, Lesley and Chin, Andrew R and Clayton, Aled and Clerici, Stefano P and Cocks, Alex and Cocucci, Emanuele and Coffey, Robert J and Cordeiro-da-Silva, Anabela and Couch, Yvonne and Coumans, Frank AW and Coyle, Beth and Crescitelli, Rossella and Criado, Miria Ferreira and D'Souza-Schorey, Crislyn and Das, Saumya and Datta Chaudhuri, Amrita and de Candia, Paola and De Santana, Eliezer F and De Wever, Olivier and del Portillo, Hernando A and Demaret, Tanguy and Deville, Sarah and Devitt, Andrew and Dhondt, Bert and Di Vizio, Dolores and Dieterich, Lothar C and Dolo, Vincenza and Dominguez Rubio, Ana Paula and Dominici, Massimo and Dourado, Mauricio R and Driedonks, Tom AP and Duarte, Filipe V and Duncan, Heather M and Eichenberger, Ramon M and Ekström, Karin and EL Andaloussi, Samir and Elie-Caille, Celine and Erdbrügger, Uta and Falcón-Pérez, Juan M and Fatima, Farah and Fish, Jason E and Flores-Bellver, Miguel and Försönits, András and Frelet-Barrand, Annie and ... and Institute of Clinical Sciences, Department of Biomaterials and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, Avdelningen för kirurgi and Institute of Clinical Sciences, Department of Surgery and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning and Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap and Institute of Medicine, Department of Rheumatology and Inflammation Research and Krefting Research Centre
Journal of Extracellular Vesicles, ISSN 2001-3078, 12/2018, Volume 7, Issue 1, pp. 1535750 - 43
Journal Article
by Thery, C and Witwer, KW and Aikawa, E and Alcaraz, MJ and Anderson, JD and Andriantsitohaina, R and Antoniou, A and Arab, T and Archer, F and Atkin-Smith, GK and Ayre, DC and Bach, JM and Bachurski, D and Baharvand, H and Balaj, L and Baldacchino, S and Bauer, NN and Baxter, AA and Bebawy, M and Beckham, C and Zavec, AB and Benmoussa, A and Berardi, AC and Bergese, P and Bielska, E and Blenkiron, C and Bobis-Wozowicz, S and Boilard, E and Boireau, W and Bongiovanni, A and Borras, FE and Bosch, S and Boulanger, CM and Breakefield, X and Breglio, AM and Brennan, MA and Brigstock, DR and Brisson, A and Broekman, MLD and Bromberg, JF and Bryl-Gorecka, P and Buch, S and Buck, AH and Burger, D and Busatto, S and Buschmann, D and Bussolati, B and Buzas, EI and Byrd, JB and Camussi, G and Carter, DRF and Caruso, S and Chamley, LW and Chang, YT and Chen, CC and Chen, S and Cheng, L and Chin, AR and Clayton, A and Clerici, SP and Cocks, A and Cocucci, E and Coffey, RJ and Cordeiro-da-Silva, A and Couch, Y and Coumans, FAW and Coyle, B and Crescitelli, R and Criado, MF and D'Souza-Schorey, C and Das, S and Chaudhuri, AD and de Candia, P and De Santana, EF and De Wever, O and del Portillo, HA and Demaret, T and Deville, S and Devitt, A and Dhondt, B and Di Vizio, D and Dieterich, LC and Dolo, V and Rubio, APD and Dominici, M and Dourado, MR and Driedonks, TAP and Duarte, FV and Duncan, HM and Eichenberger, RM and Ekstrom, K and Andaloussi, SEL and Elie-Caille, C and Erdbrugger, U and Falcon-Perez, JM and Fatima, F and Fish, JE and Flores-Bellver, M and Forsonits, A and Frelet-Barrand, A and ...
JOURNAL OF EXTRACELLULAR VESICLES, ISSN 2001-3078, 11/2018, Volume 7, Issue 1
Journal Article