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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2578 - 2589
Abstract Background Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl),... 
Cardiovascular | Internal Medicine | coronary artery disease | gene sequencing | genetics | low-density lipoprotein cholesterol | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | MYOCARDIAL-INFARCTION | RANDOMIZED-TRIALS | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | RISK | MUTATION DETECTION RATE | CORONARY-HEART-DISEASE | ASSOCIATION | PARTICIPANTS | Receptors, LDL - genetics | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Case-Control Studies | Genetic Variation | Cholesterol, LDL - blood | Female | Heterozygote | Coronary Artery Disease - epidemiology | Sequence Analysis | Cohort Studies | Hypercholesterolemia - epidemiology | Hyperlipoproteinemia Type II - genetics | Medical colleges | Care and treatment | Low density lipoproteins | Genes | Coronary heart disease | Population genetics | Epidemiology | Blood | Hypercholesterolemia | Analysis and chemistry | Atherosclerosis | Genetic research | Genetic aspects | Diagnosis | Research institutes | Cardiology | Trans fatty acids | Heart attacks | Cardiovascular disease | Lipids | Apolipoproteins | Low density lipoprotein | Cholesterol | Proteins | Studies | Confidence intervals | Consortia | Algorithms | Coronary vessels | Population | Mutation | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 375, Issue 9711, pp. 283 - 293
Journal Article
by Voight, Benjamin F, PhD and Peloso, Gina M, PhD and Orho-Melander, Marju, PhD and Frikke-Schmidt, Ruth, DMSc and Barbalic, Maja, PhD and Jensen, Majken K, PhD and Hindy, George, MD and Hólm, Hilma, MD and Ding, Eric L, ScD and Johnson, Toby, PhD and Schunkert, Heribert, Prof and Samani, Nilesh J, Prof and Clarke, Robert, MD and Hopewell, Jemma C, PhD and Thompson, John F, Prof and Li, Mingyao, PhD and Thorleifsson, Gudmar, PhD and Newton-Cheh, Christopher, MD and Musunuru, Kiran, MD and Pirruccello, James P, BS and Saleheen, Danish, MBBS and Chen, Li, MSc and Stewart, Alexandre FR, PhD and Schillert, Arne, PhD and Thorsteinsdottir, Unnur, PhD and Thorgeirsson, Gudmundur, MD and Anand, Sonia, Prof and Engert, James C, PhD and Morgan, Thomas, MD and Spertus, John, Prof and Stoll, Monika, Prof and Berger, Klaus, Prof and Martinelli, Nicola, MD and Girelli, Domenico, Prof and McKeown, Pascal P, Prof and Patterson, Christopher C, PhD and Epstein, Stephen E, MD and Devaney, Joseph, PhD and Burnett, Mary-Susan, PhD and Mooser, Vincent, MD and Ripatti, Samuli, PhD and Surakka, Ida, BSci and Nieminen, Markku S, Prof and Sinisalo, Juha, MD and Lokki, Marja-Liisa, PhD and Perola, Markus, Prof and Havulinna, Aki, PhD and de Faire, Ulf, Prof and Gigante, Bruna, MD and Ingelsson, Erik, PhD and Zeller, Tanja, PhD and Wild, Philipp, MD and de Bakker, Paul I W, Prof and Klungel, Olaf H, PhD and Maitland-van der Zee, Anke-Hilse, PhD and Peters, Bas J M, PhD and de Boer, Anthonius, Prof and Grobbee, Diederick E, Prof and Kamphuisen, Pieter W, PhD and Deneer, Vera H M, PhD and Elbers, Clara C, PhD and Onland-Moret, N Charlotte, PhD and Hofker, Marten H, Prof and Wijmenga, Cisca, Prof and Verschuren, WM Monique, PhD and Boer, Jolanda MA, PhD and van der Schouw, Yvonne T, Prof and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem, PhD and Willer, Cristen, PhD and Do, Ron, PhD and Ordovas, Jose M, Prof and Abecasis, Gonçalo R, Prof and Boehnke, Michael, Prof and Mohlke, Karen L, PhD and Daly, Mark J, PhD and Guiducci, Candace, BS and Burtt, Noël P, BS and Surti, Aarti, BS and Gonzalez, Elena, BS and Purcell, Shaun, PhD and Gabriel, Stacey, PhD and Marrugat, Jaume, PhD and Peden, John, PhD and Erdmann, Jeanette, PhD and Diemert, Patrick, MD and Willenborg, Christina, MSc and König, Inke R, PhD and Fischer, Marcus, MD and Hengstenberg, Christian, MD and Ziegler, Andreas, PhD and Buysschaert, Ian, MD and Lambrechts, Diether, PhD and Van de Werf, Frans, Prof and Fox, Keith A, Prof and El Mokhtari, Nour Eddine, MD and Rubin, Diana, MD and Schrezenmeir, Jürgen, PhD and Schreiber, Stefan, Prof and ...
Lancet, The, ISSN 0140-6736, 08/2012, Volume 380, Issue 9841, pp. 572 - 580
Journal Article
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10081, pp. 1799 - 1808
Summary Background Dual antiplatelet therapy (DAPT), aspirin plus a P2Y12 inhibitor, is the standard antithrombotic treatment following acute coronary... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | PRACTICE GUIDELINES | MYOCARDIAL-INFARCTION | STENT THROMBOSIS | IN-VIVO | AMERICAN-COLLEGE | ASSOCIATION TASK-FORCE | PHASE-II | ST-SEGMENT ELEVATION | SECONDARY PREVENTION | ANTIPLATELET THERAPY | Purinergic P2Y Receptor Antagonists - administration & dosage | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Myocardial Infarction - diagnostic imaging | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Coronary Angiography - methods | Adenosine - therapeutic use | Thrombolytic Therapy - methods | Ticlopidine - administration & dosage | Female | Myocardial Infarction - physiopathology | Aspirin - therapeutic use | Platelet Aggregation Inhibitors - therapeutic use | Ticagrelor | Electrocardiography - methods | Purinergic P2Y Receptor Antagonists - therapeutic use | Rivaroxaban - therapeutic use | Double-Blind Method | Treatment Outcome | Adenosine - administration & dosage | Ticlopidine - analogs & derivatives | Acute Coronary Syndrome - drug therapy | Drug Therapy, Combination - methods | Factor Xa Inhibitors - therapeutic use | Myocardial Infarction - drug therapy | Adenosine - analogs & derivatives | Clopidogrel | Aged | Hemorrhage - chemically induced | Medical research | Medical colleges | Aspirin | Mortality | Cardiac patients | Clinical trials | Medicine, Experimental | Dosage and administration | Research institutes | France | Coronary heart disease | Analysis | Myocardial infarction | Therapy | Angiography | Medical services | Disorders | Angina | Bleeding | Elevation | Randomization | Motivation | Atherosclerosis | Bioindicators | Safety | Drug therapy | Drug dosages | Heart diseases | Anticoagulants | Research & development--R&D | Strata | Coronary artery | Patients | Thrombosis | Thrombolysis | Inhibitors | Arteriosclerosis | Biomarkers | Infarction | Acute coronary syndromes | Index Medicus | Abridged Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 2, pp. 111 - 121
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7616, pp. 285 - 291
Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe... 
HUMAN-DISEASE | EVOLUTION | MULTIDISCIPLINARY SCIENCES | MUTATION | GUIDELINES | FRAMEWORK | SEQUENCE VARIANTS | NETWORKS | DISCOVERY | HUMAN-POPULATION HISTORY | Genetic aspects | Research | Man | Human beings | Genetic variation | Analysis | Datasets | Proteins | Disease | Genes | Principal components analysis | Genetics | Genomes | Data bases | Index Medicus
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 12/2016, Volume 68, Issue 25, pp. 2761 - 2772
Journal Article