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Critical Care Medicine, ISSN 0090-3493, 01/2020, Volume 48, Issue 1 Suppl 1, pp. 253 - 253
Journal Article
Blood, ISSN 0006-4971, 11/2019
Key Points PF4 improves outcome in sepsis by stabilizing NETs and enhancing NET-mediated microbial entrapment. KKO, an Fc-modified HIT-like antibody, further... 
Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1164 - 1164
Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often required to support infants with congenital defects, congenital heart disease,... 
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 11/2019, Volume 17, Issue 11, pp. 1956 - 1965
Background The presence of a hypercoagulable disorder such as heparin‐induced thrombocytopenia (HIT) may protect against anticoagulant‐associated bleeding.... 
heparin/adverse event | anticoagulants/adverse event | thrombosis | anticoagulants/therapeutic use | thrombocytopenia | Thrombocytopenia | Anticoagulants | Renal function | Mortality | Heparin | Thrombosis | Bleeding
Journal Article
Blood Advances, ISSN 2473-9529, 10/2019, Volume 3, Issue 19, pp. 2778 - 2789
Key Points In a whole blood assay, ICs cause neutrophil activation and degranulation. Individuals have a fixed susceptibility to neutrophil activation by ICs. 
Journal Article
Journal of Clinical and Translational Science, ISSN 2059-8661, 03/2019, Volume 3, Issue s1, pp. 67 - 68
OBJECTIVES/SPECIFIC AIMS: 1.Identify barriers to pursuing research for physician trainees 2.Develop a sustainable pipeline of physician-scientists at Duke... 
Medical personnel | Population studies | Students | Laboratories | Research programs | Research funding
Journal Article
BLOOD, ISSN 0006-4971, 02/2019, Volume 133, Issue 9, pp. 902 - 905
Recent multistate outbreaks of coagulopathy caused by brodifacoum-tainted synthetic cannabinoids or "fake weed" highlight the public health impact of... 
RESISTANT | MARIJUANA | PHARMACOKINETICS | WARFARIN | INGESTION | RODENTICIDE | BRODIFACOUM | OUTBREAK | VITAMIN-K-1 | HEMATOLOGY
Journal Article
Lab on a Chip, ISSN 1473-0197, 2019, Volume 19, Issue 3, pp. 394 - 402
Platelet separation is a crucial step for both blood donation and treatment of essential thrombocytosis. Here we present an acoustofluidic device that is... 
STANDING-WAVE | WHOLE-BLOOD | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | EXOSOMES | IN-VITRO PROPERTIES | PARTICLE MANIPULATION | NANOSCIENCE & NANOTECHNOLOGY | RICH | ACOUSTIC RADIATION FORCE | CHEMISTRY, MULTIDISCIPLINARY | AMICUS
Journal Article
ISSN 1473-0197, 1/2019, Volume 19, Issue 3, pp. 394 - 42
Platelet separation is a crucial step for both blood donation and treatment of essential thrombocytosis. Here we present an acoustofluidic device that is... 
Journal Article
Lab on a Chip, ISSN 1473-0197, 01/2019, Volume 19, Issue 3, pp. 394 - 402
Platelet separation is a crucial step for both blood donation and treatment of essential thrombocytosis. Here we present an acoustofluidic device that is... 
White blood cells | Sound waves | Separation | Blood platelets | Blood & organ donations | Biocompatibility | Platelets
Journal Article
Blood, ISSN 0006-4971, 12/2018, Volume 132, Issue 23, pp. 2431 - 2440
The mechanisms by which exposure to heparin initiates antibody responses in many, if not most, recipients are poorly understood. We recently demonstrated that... 
Plenary Paper
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 271 - 271
Abstract Sepsis is characterized by life-threatening organ dysfunction caused by a dysregulated response to infection. Neutrophils play a crucial role in... 
Journal Article
Blood advances, ISSN 2473-9529, 11/2018, Volume 2, Issue 22, pp. 3360 - 3392
Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and... 
Journal Article
Blood advances, ISSN 2473-9529, 11/2018, Volume 2, Issue 22, pp. 3155 - 3162
The HIT Expert Probability (HEP) score compared favorably with the 4Ts score in a retrospective study. We assessed the diagnostic accuracy of the HEP score... 
Journal Article
JCI INSIGHT, ISSN 2379-3708, 09/2018, Volume 3, Issue 18
Heparin-induced thrombocytopenia (HIT) is an immune-mediated thrombocytopenic disorder associated with a severe prothrombotic state. We investigated whether... 
PATHOGENESIS | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | ANTIGENIC COMPLEXES | PLATELET | DEGRADATION | HEPARIN-INDUCED THROMBOCYTOPENIA | FC-GAMMA-RIIA | EXTRACELLULAR TRAPS | PLATELET-FACTOR-4 | ANTIPHOSPHOLIPID SYNDROME
Journal Article
Nature Biotechnology, ISSN 1087-0156, 08/2018, Volume 36, Issue 7, pp. 606 - 613
Journal Article