Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. AB130 - AB130
Rationale Although an oral food challenge is the gold standard for confirming peanut allergy, skin prick tests and peanut specific IgE and component testing...
Allergy and Immunology | Immunoglobulin E | Skin | Peanuts | Food allergies
Allergy and Immunology | Immunoglobulin E | Skin | Peanuts | Food allergies
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 2, pp. 424 - 432.e8
Background The hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by infections of the lung and skin, elevated serum IgE, and involvement of...
Allergy and Immunology | STAT3 mutations | Hyper-IgE syndrome | diagnostic guidelines | T H17 cells | HIES | Job syndrome | CELLS | ALLERGY | HOST-DEFENSE | IMMUNOLOGY | T(H)17 cells | Job Syndrome - immunology | Job Syndrome - genetics | Enzyme-Linked Immunosorbent Assay | Job Syndrome - diagnosis | Cell Separation | Humans | Middle Aged | Interleukin-17 - immunology | Child, Preschool | Infant | Male | Immunoglobulin E - blood | Young Adult | Flow Cytometry | T-Lymphocytes, Helper-Inducer - immunology | Adolescent | Polymerase Chain Reaction | Adult | Female | Mutation | Child | STAT3 Transcription Factor - genetics | Practice Guidelines as Topic | Allergy | Medical colleges | Asthma in children | Immunodeficiency | Immunoglobulin E | Bone marrow | Transplantation | Diagnosis | Children | Gene therapy | Health aspects | Allergic reaction | Signal transduction | Cell culture | Genotype & phenotype | Pneumonia | Hypotheses | Fractures | Cytokines | Patients | Age | Deoxyribonucleic acid--DNA
Allergy and Immunology | STAT3 mutations | Hyper-IgE syndrome | diagnostic guidelines | T H17 cells | HIES | Job syndrome | CELLS | ALLERGY | HOST-DEFENSE | IMMUNOLOGY | T(H)17 cells | Job Syndrome - immunology | Job Syndrome - genetics | Enzyme-Linked Immunosorbent Assay | Job Syndrome - diagnosis | Cell Separation | Humans | Middle Aged | Interleukin-17 - immunology | Child, Preschool | Infant | Male | Immunoglobulin E - blood | Young Adult | Flow Cytometry | T-Lymphocytes, Helper-Inducer - immunology | Adolescent | Polymerase Chain Reaction | Adult | Female | Mutation | Child | STAT3 Transcription Factor - genetics | Practice Guidelines as Topic | Allergy | Medical colleges | Asthma in children | Immunodeficiency | Immunoglobulin E | Bone marrow | Transplantation | Diagnosis | Children | Gene therapy | Health aspects | Allergic reaction | Signal transduction | Cell culture | Genotype & phenotype | Pneumonia | Hypotheses | Fractures | Cytokines | Patients | Age | Deoxyribonucleic acid--DNA
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 3, pp. 825 - 830.e9
Background Inherited deficiencies of IL-10 or IL-10 receptor (IL-10R) lead to immune dysregulation with life-threatening early-onset enterocolitis. Objectives...
Allergy and Immunology | colectomy | hematopoietic stem cell transplantation | mutations | IL-10 receptor | enterocolitis | IL-10 | COMPLEX | CROHNS-DISEASE | INTERLEUKIN-10 RECEPTOR | CYTOKINE | IMMUNOLOGY | FAMILY | INFLAMMATORY-BOWEL-DISEASE | GENE | ALLERGY | IMMUNODEFICIENCY | Immunologic Deficiency Syndromes - therapy | Interleukin-10 - deficiency | Immunologic Deficiency Syndromes - complications | Colitis - genetics | Humans | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Colitis - etiology | Colitis - therapy | Colitis - diagnosis | Immunologic Deficiency Syndromes - genetics | Adult | Female | Mutation | Receptors, Interleukin-10 - deficiency | Immunologic Deficiency Syndromes - diagnosis | Child | Infant, Newborn | Medical colleges | Patient outcomes | Children's hospitals | Immunodeficiency | Stem cells | Transplantation | Hematopoietic stem cells | Inflammatory bowel disease | Proteins | Pediatrics | Hospitals | Disease | Lymphocytes | Colleges & universities | Family medical history | Patients | Deoxyribonucleic acid--DNA
Allergy and Immunology | colectomy | hematopoietic stem cell transplantation | mutations | IL-10 receptor | enterocolitis | IL-10 | COMPLEX | CROHNS-DISEASE | INTERLEUKIN-10 RECEPTOR | CYTOKINE | IMMUNOLOGY | FAMILY | INFLAMMATORY-BOWEL-DISEASE | GENE | ALLERGY | IMMUNODEFICIENCY | Immunologic Deficiency Syndromes - therapy | Interleukin-10 - deficiency | Immunologic Deficiency Syndromes - complications | Colitis - genetics | Humans | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Colitis - etiology | Colitis - therapy | Colitis - diagnosis | Immunologic Deficiency Syndromes - genetics | Adult | Female | Mutation | Receptors, Interleukin-10 - deficiency | Immunologic Deficiency Syndromes - diagnosis | Child | Infant, Newborn | Medical colleges | Patient outcomes | Children's hospitals | Immunodeficiency | Stem cells | Transplantation | Hematopoietic stem cells | Inflammatory bowel disease | Proteins | Pediatrics | Hospitals | Disease | Lymphocytes | Colleges & universities | Family medical history | Patients | Deoxyribonucleic acid--DNA
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 133, Issue 1, pp. 265 - 267
Inherited deficiency of the C1q component of the classical complement pathway is a severe autosomal recessive immunodeficiency disease associated with a high...
Allergy and Immunology | COMPLEMENT | MICE | IMMUNOLOGY | ALLERGY | Autoantibodies - blood | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Postoperative Complications - prevention & control | Child, Preschool | Cardiolipins - immunology | Male | Recovery of Function | Antibodies, Monoclonal, Humanized - administration & dosage | Pakistan | Ribonucleoproteins - immunology | Transplantation Conditioning - methods | Immunologic Deficiency Syndromes - immunology | Child | Graft vs Host Disease - etiology | Immunologic Deficiency Syndromes - therapy | Hematopoietic Stem Cell Transplantation | Rituximab | Alemtuzumab | Complement C1q - genetics | Disease-Free Survival | Pedigree | Adolescent | Graft vs Host Disease - prevention & control | Consanguinity | Chimerism | Transplantation | Hematopoietic stem cells | Lupus | Bone marrow | Transplants & implants | Autoimmune diseases | Stem cells
Allergy and Immunology | COMPLEMENT | MICE | IMMUNOLOGY | ALLERGY | Autoantibodies - blood | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Postoperative Complications - prevention & control | Child, Preschool | Cardiolipins - immunology | Male | Recovery of Function | Antibodies, Monoclonal, Humanized - administration & dosage | Pakistan | Ribonucleoproteins - immunology | Transplantation Conditioning - methods | Immunologic Deficiency Syndromes - immunology | Child | Graft vs Host Disease - etiology | Immunologic Deficiency Syndromes - therapy | Hematopoietic Stem Cell Transplantation | Rituximab | Alemtuzumab | Complement C1q - genetics | Disease-Free Survival | Pedigree | Adolescent | Graft vs Host Disease - prevention & control | Consanguinity | Chimerism | Transplantation | Hematopoietic stem cells | Lupus | Bone marrow | Transplants & implants | Autoimmune diseases | Stem cells
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 2, pp. AB199 - AB199
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 141, Issue 1, pp. 457 - 458
To the Editor: We read with interest the report by van Erp et al1 showing that in 81 Swedish children with suspected peanut allergy, 0.1 and 5.0 kUA/L Ara h2...
Allergy and Immunology | IMMUNOLOGY | ALLERGY | ARA H 2 | IGE | CHILDREN | Allergens | Skin Tests | Basophils | Humans | Arachis - immunology | Immunoglobulin E | Peanut Hypersensitivity | Child | Peanuts | Food allergies | Food hypersensitivity
Allergy and Immunology | IMMUNOLOGY | ALLERGY | ARA H 2 | IGE | CHILDREN | Allergens | Skin Tests | Basophils | Humans | Arachis - immunology | Immunoglobulin E | Peanut Hypersensitivity | Child | Peanuts | Food allergies | Food hypersensitivity
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 5, pp. 1006 - 1015.e4
Background Accumulating evidence implicates TH 17 cytokines in protection against Candida species infections, but the clinical relevance is not clear. Chronic...
Allergy and Immunology
Allergy and Immunology
Journal Article
Journal of Allergy and Clinical Immunology: In Practice, ISSN 2213-2198, 2014, Volume 2, Issue 4, pp. 388 - 395
A 7-year-old girl presented with atopic dermatitis (AD) that did not respond to standard therapy. She was avoiding dairy, egg, and wheat in her diet because of...
Internal Medicine | Allergy and Immunology | Food allergy | Hyper IgE syndrome | Atopic dermatitis | Staphylococcus aureus | Zinc | MRSA | ANTIBIOTIC-RESISTANCE | IMMUNOLOGY | RESISTANT STAPHYLOCOCCUS-AUREUS | ADHERENCE | CELIAC-DISEASE | METHICILLIN-RESISTANT | ALLERGY | ECZEMA HERPETICUM | DOUBLE-BLIND | FILAGGRIN MUTATIONS | EOSINOPHILIC ESOPHAGITIS | Administration, Sublingual | Skin - microbiology | Humans | Dermatitis, Atopic - therapy | Staphylococcal Infections - complications | Immunoglobulin E - blood | Dermatitis, Atopic - diagnosis | Anti-Bacterial Agents - therapeutic use | Obsessive-Compulsive Disorder - complications | Obsessive-Compulsive Disorder - diagnosis | Female | Child | Skin - pathology | Skin - immunology | Obsessive-Compulsive Disorder - therapy | Feeding Behavior | Dermatitis, Atopic - complications | Staphylococcal Infections - therapy | Staphylococcal Infections - diagnosis | Animals | Quality of Life | Cognitive Therapy | Pyroglyphidae | Staphylococcus aureus - immunology | Desensitization, Immunologic - methods | Food allergies | Dermatitis | Allergies | Milk
Internal Medicine | Allergy and Immunology | Food allergy | Hyper IgE syndrome | Atopic dermatitis | Staphylococcus aureus | Zinc | MRSA | ANTIBIOTIC-RESISTANCE | IMMUNOLOGY | RESISTANT STAPHYLOCOCCUS-AUREUS | ADHERENCE | CELIAC-DISEASE | METHICILLIN-RESISTANT | ALLERGY | ECZEMA HERPETICUM | DOUBLE-BLIND | FILAGGRIN MUTATIONS | EOSINOPHILIC ESOPHAGITIS | Administration, Sublingual | Skin - microbiology | Humans | Dermatitis, Atopic - therapy | Staphylococcal Infections - complications | Immunoglobulin E - blood | Dermatitis, Atopic - diagnosis | Anti-Bacterial Agents - therapeutic use | Obsessive-Compulsive Disorder - complications | Obsessive-Compulsive Disorder - diagnosis | Female | Child | Skin - pathology | Skin - immunology | Obsessive-Compulsive Disorder - therapy | Feeding Behavior | Dermatitis, Atopic - complications | Staphylococcal Infections - therapy | Staphylococcal Infections - diagnosis | Animals | Quality of Life | Cognitive Therapy | Pyroglyphidae | Staphylococcus aureus - immunology | Desensitization, Immunologic - methods | Food allergies | Dermatitis | Allergies | Milk
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 4, pp. 993 - 1006.e1
Background Follicular helper T (TFH ) cells underpin T cell–dependent humoral immunity and the success of most vaccines. TFH cells also contribute to human...
Allergy and Immunology | cytokine signaling | humoral immunity | Follicular helper T cells | primary immunodeficiencies | IFN-GAMMA | AGAMMAGLOBULINEMIA | PHENOTYPE | IL-21 RECEPTOR | IMMUNOLOGY | TRANSCRIPTION FACTOR STAT3 | DEFICIENCY | B-CELLS | COMMITMENT | ALLERGY | ANTIBODY-RESPONSES | T-Lymphocyte Subsets - immunology | Cell Proliferation - genetics | Lymphocyte Activation | Humans | Immunity, Humoral - genetics | Cells, Cultured | Signal Transduction - genetics | I-kappa B Kinase - genetics | Interferon-gamma - metabolism | Mutation - genetics | STAT1 Transcription Factor - genetics | Cell Differentiation - genetics | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | B-Lymphocytes - immunology | CD40 Ligand - genetics | T-Lymphocytes, Helper-Inducer - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | Immunologic Deficiency Syndromes - genetics | Immunologic Memory | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Receptors, Cytokine - genetics | STAT3 Transcription Factor - genetics | Autoimmunity | Care and treatment | Genetic aspects | Immunodeficiency | Antigens | Immunoglobulins | Cytokines | Lymphocytes | Human immunodeficiency virus--HIV | T cell receptors | Infections | Gene expression
Allergy and Immunology | cytokine signaling | humoral immunity | Follicular helper T cells | primary immunodeficiencies | IFN-GAMMA | AGAMMAGLOBULINEMIA | PHENOTYPE | IL-21 RECEPTOR | IMMUNOLOGY | TRANSCRIPTION FACTOR STAT3 | DEFICIENCY | B-CELLS | COMMITMENT | ALLERGY | ANTIBODY-RESPONSES | T-Lymphocyte Subsets - immunology | Cell Proliferation - genetics | Lymphocyte Activation | Humans | Immunity, Humoral - genetics | Cells, Cultured | Signal Transduction - genetics | I-kappa B Kinase - genetics | Interferon-gamma - metabolism | Mutation - genetics | STAT1 Transcription Factor - genetics | Cell Differentiation - genetics | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | B-Lymphocytes - immunology | CD40 Ligand - genetics | T-Lymphocytes, Helper-Inducer - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | Immunologic Deficiency Syndromes - genetics | Immunologic Memory | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Receptors, Cytokine - genetics | STAT3 Transcription Factor - genetics | Autoimmunity | Care and treatment | Genetic aspects | Immunodeficiency | Antigens | Immunoglobulins | Cytokines | Lymphocytes | Human immunodeficiency virus--HIV | T cell receptors | Infections | Gene expression
Journal Article
10.
Full Text
The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 402 - 412
Background Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE...
Allergy and Immunology | Primary combined immunodeficiency | autosomal recessive hyper-IgE syndrome | signal transducer and activator of transcription 3 | Molluscum contagiosum | hyper-IgE syndrome | dedicator of cytokinesis 8 | SURVIVAL | BONE-MARROW-TRANSPLANTATION | STAT3 | GLYCOSYLATION | IMMUNOLOGY | ALLERGY | DOCK8 DEFICIENCY | DISORDER | MUTATIONS | STEM-CELL TRANSPLANTATION | IMMUNODEFICIENCY | Job Syndrome - genetics | Job Syndrome - mortality | Humans | Middle Aged | Child, Preschool | Male | Support Vector Machine | Virus Diseases - complications | Eosinophils - immunology | Immunoglobulin E - blood | CD4-Positive T-Lymphocytes - immunology | Bacterial Infections - genetics | Eosinophils - pathology | Virus Diseases - genetics | Child | Guanine Nucleotide Exchange Factors - deficiency | STAT3 Transcription Factor - genetics | Skin Diseases - mortality | Immunoglobulin M - genetics | Guanine Nucleotide Exchange Factors - genetics | Virus Diseases - immunology | Skin Diseases - immunology | Antigens, Viral - immunology | Phenotype | Skin Diseases - complications | Job Syndrome - complications | Adolescent | Survival Analysis | Virus Diseases - mortality | Mutation | STAT3 Transcription Factor - immunology | CD8-Positive T-Lymphocytes - immunology | Bacterial Infections - mortality | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - pathology | Skin Diseases - genetics | Antigens, Bacterial - immunology | Infant | Antigens, Bacterial - blood | CD4-Positive T-Lymphocytes - pathology | Antigens, Viral - blood | Bacterial Infections - complications | Immunoglobulin E - genetics | Bacterial Infections - immunology | Adult | Female | Immunoglobulin M - blood | Guanine Nucleotide Exchange Factors - immunology | Lymphocyte Count | Genotype & phenotype | Immunoglobulins | Laboratories | Lymphocytes | Families & family life | Lymphomas | Viral infections | Deoxyribonucleic acid--DNA | Immunoglobulin M | Immunoglobulin E | CD8-Positive T-Lymphocytes | Life Sciences | Antigens, Viral | Bacterial Infections | Job Syndrome | CD4-Positive T-Lymphocytes | Virus Diseases | Skin Diseases | Antigens, Bacterial | Guanine Nucleotide Exchange Factors | STAT3 Transcription Factor | Eosinophils
Allergy and Immunology | Primary combined immunodeficiency | autosomal recessive hyper-IgE syndrome | signal transducer and activator of transcription 3 | Molluscum contagiosum | hyper-IgE syndrome | dedicator of cytokinesis 8 | SURVIVAL | BONE-MARROW-TRANSPLANTATION | STAT3 | GLYCOSYLATION | IMMUNOLOGY | ALLERGY | DOCK8 DEFICIENCY | DISORDER | MUTATIONS | STEM-CELL TRANSPLANTATION | IMMUNODEFICIENCY | Job Syndrome - genetics | Job Syndrome - mortality | Humans | Middle Aged | Child, Preschool | Male | Support Vector Machine | Virus Diseases - complications | Eosinophils - immunology | Immunoglobulin E - blood | CD4-Positive T-Lymphocytes - immunology | Bacterial Infections - genetics | Eosinophils - pathology | Virus Diseases - genetics | Child | Guanine Nucleotide Exchange Factors - deficiency | STAT3 Transcription Factor - genetics | Skin Diseases - mortality | Immunoglobulin M - genetics | Guanine Nucleotide Exchange Factors - genetics | Virus Diseases - immunology | Skin Diseases - immunology | Antigens, Viral - immunology | Phenotype | Skin Diseases - complications | Job Syndrome - complications | Adolescent | Survival Analysis | Virus Diseases - mortality | Mutation | STAT3 Transcription Factor - immunology | CD8-Positive T-Lymphocytes - immunology | Bacterial Infections - mortality | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - pathology | Skin Diseases - genetics | Antigens, Bacterial - immunology | Infant | Antigens, Bacterial - blood | CD4-Positive T-Lymphocytes - pathology | Antigens, Viral - blood | Bacterial Infections - complications | Immunoglobulin E - genetics | Bacterial Infections - immunology | Adult | Female | Immunoglobulin M - blood | Guanine Nucleotide Exchange Factors - immunology | Lymphocyte Count | Genotype & phenotype | Immunoglobulins | Laboratories | Lymphocytes | Families & family life | Lymphomas | Viral infections | Deoxyribonucleic acid--DNA | Immunoglobulin M | Immunoglobulin E | CD8-Positive T-Lymphocytes | Life Sciences | Antigens, Viral | Bacterial Infections | Job Syndrome | CD4-Positive T-Lymphocytes | Virus Diseases | Skin Diseases | Antigens, Bacterial | Guanine Nucleotide Exchange Factors | STAT3 Transcription Factor | Eosinophils
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 4, pp. 988 - 997.e6
Background Common variable immunodeficiency (CVID) is usually well controlled with immunoglobulin substitution and immunomodulatory drugs. A subgroup of...
Allergy and Immunology | Common variable immunodeficiency | immunologic reconstitution | survival | hematopoietic stem cell transplantation | immunoglobulin substitution/replacement | mortality | hypogammaglobulinemia | outcome | BONE-MARROW-TRANSPLANTATION | ACUTE GVHD | DISORDERS | CLASSIFICATION | SEVERE APLASTIC-ANEMIA | EUROPEAN GROUP | VERSUS-HOST-DISEASE | WORKING PARTY | Journal Article | B-CELL | Research Support, Non-U.S. Gov't | Multicenter Study | BLOOD | ABNORMALITIES | BONE-MARROW | IMMUNOLOGY | ALLERGY | Follow-Up Studies | Humans | Middle Aged | Graft Survival | Male | Treatment Outcome | Common Variable Immunodeficiency - complications | Cause of Death | Young Adult | Common Variable Immunodeficiency - mortality | Common Variable Immunodeficiency - therapy | Adolescent | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Graft vs Host Disease - prevention & control | Retrospective Studies | Transplantation Conditioning | Child | Graft vs Host Disease - etiology | Hematopoietic Stem Cells | Complications and side effects | Hospitals | Mortality | Stem cells | Immunological deficiency syndromes | Transplantation | Hematopoietic stem cells | Cytomegalovirus | Life expectancy | Transplants & implants | Lung diseases | Liver | Values | Infections | Patients | Variables | Cell growth | Software | Lymphomas | Age
Allergy and Immunology | Common variable immunodeficiency | immunologic reconstitution | survival | hematopoietic stem cell transplantation | immunoglobulin substitution/replacement | mortality | hypogammaglobulinemia | outcome | BONE-MARROW-TRANSPLANTATION | ACUTE GVHD | DISORDERS | CLASSIFICATION | SEVERE APLASTIC-ANEMIA | EUROPEAN GROUP | VERSUS-HOST-DISEASE | WORKING PARTY | Journal Article | B-CELL | Research Support, Non-U.S. Gov't | Multicenter Study | BLOOD | ABNORMALITIES | BONE-MARROW | IMMUNOLOGY | ALLERGY | Follow-Up Studies | Humans | Middle Aged | Graft Survival | Male | Treatment Outcome | Common Variable Immunodeficiency - complications | Cause of Death | Young Adult | Common Variable Immunodeficiency - mortality | Common Variable Immunodeficiency - therapy | Adolescent | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Graft vs Host Disease - prevention & control | Retrospective Studies | Transplantation Conditioning | Child | Graft vs Host Disease - etiology | Hematopoietic Stem Cells | Complications and side effects | Hospitals | Mortality | Stem cells | Immunological deficiency syndromes | Transplantation | Hematopoietic stem cells | Cytomegalovirus | Life expectancy | Transplants & implants | Lung diseases | Liver | Values | Infections | Patients | Variables | Cell growth | Software | Lymphomas | Age
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 2, pp. 400 - 411.e9
Background The capacity of CD8+ T cells to control infections and mediate antitumor immunity requires the development and survival of effector and memory...
Allergy and Immunology | Autosomal dominant hyper-IgE syndrome | human CD8+ T cells | memory | differentiation | STAT1 | STAT3 | IL-21 | IFN-GAMMA | IL-21 RECEPTOR | IL-15 | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | INBORN-ERRORS | CUTTING EDGE | ADAPTIVE IMMUNITY | NK CELLS | ALLERGY | IN-VIVO | COMMON GAMMA-CHAIN | human CD8(+) T cells | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - cytology | Job Syndrome - genetics | Receptors, Interleukin-21 - immunology | Humans | Receptors, Interleukin-21 - genetics | Receptors, Interleukin-21 - metabolism | Interleukins - metabolism | Cell Differentiation - genetics | Cell Differentiation - immunology | Interleukins - genetics | Interleukins - immunology | CD8-Positive T-Lymphocytes - metabolism | Immunologic Memory | Job Syndrome - pathology | Mutation | CD8-Positive T-Lymphocytes - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | T cell receptors | Kinases | Viral infections | Immune system
Allergy and Immunology | Autosomal dominant hyper-IgE syndrome | human CD8+ T cells | memory | differentiation | STAT1 | STAT3 | IL-21 | IFN-GAMMA | IL-21 RECEPTOR | IL-15 | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | INBORN-ERRORS | CUTTING EDGE | ADAPTIVE IMMUNITY | NK CELLS | ALLERGY | IN-VIVO | COMMON GAMMA-CHAIN | human CD8(+) T cells | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - cytology | Job Syndrome - genetics | Receptors, Interleukin-21 - immunology | Humans | Receptors, Interleukin-21 - genetics | Receptors, Interleukin-21 - metabolism | Interleukins - metabolism | Cell Differentiation - genetics | Cell Differentiation - immunology | Interleukins - genetics | Interleukins - immunology | CD8-Positive T-Lymphocytes - metabolism | Immunologic Memory | Job Syndrome - pathology | Mutation | CD8-Positive T-Lymphocytes - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | T cell receptors | Kinases | Viral infections | Immune system
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 2, pp. 615 - 619.e1
Patient 4 (sibling to patient 3) was well until he presented with inflammatory colitis and Hodgkin lymphoma (inguinal and para-aortic region) at age 16...
Allergy and Immunology | IMMUNE DYSREGULATION | MUTATIONS | IMMUNOLOGY | VARIANTS | ALLERGY | Transplantation | Hospitals | Hematopoietic stem cells | Stem cells | Pediatrics | Immunoglobulins | Transplants & implants | Lung diseases | Mortality | Parenteral nutrition | Arthritis | Patients | Children & youth | Inflammatory bowel disease | Bone marrow | Ligands | Skin | Lymphomas | Mutation | Diabetes | Age | Steroids | Neutropenia
Allergy and Immunology | IMMUNE DYSREGULATION | MUTATIONS | IMMUNOLOGY | VARIANTS | ALLERGY | Transplantation | Hospitals | Hematopoietic stem cells | Stem cells | Pediatrics | Immunoglobulins | Transplants & implants | Lung diseases | Mortality | Parenteral nutrition | Arthritis | Patients | Children & youth | Inflammatory bowel disease | Bone marrow | Ligands | Skin | Lymphomas | Mutation | Diabetes | Age | Steroids | Neutropenia
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016
Background Dedicator of cytokinesis 8 (DOCK8) deficiency is a combined immunodeficiency caused by autosomal recessive loss-of-function mutations in DOCK8 ....
Allergy and Immunology
Allergy and Immunology
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 6, pp. 1733 - 1736.e2
Initial immune investigations revealed a distinctive phenotype of a high CD4/CD8 ratio (10:1) with low numbers of CD8+ T cells (0.29 x 109/L) and normal...
Allergy and Immunology | ALLERGY | IMMUNODEFICIENCY | IMMUNOLOGY | Bone marrow | Killer cells | Transplantation | T cells | Flow cytometry | Transplants & implants | Families & family life | T cell receptors | Streptococcus infections | Proteins | Genotype & phenotype | Lymphocytes | Ulcers | Stem cells | Ligands | Age | Letter to the Editor
Allergy and Immunology | ALLERGY | IMMUNODEFICIENCY | IMMUNOLOGY | Bone marrow | Killer cells | Transplantation | T cells | Flow cytometry | Transplants & implants | Families & family life | T cell receptors | Streptococcus infections | Proteins | Genotype & phenotype | Lymphocytes | Ulcers | Stem cells | Ligands | Age | Letter to the Editor
Journal Article