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medical and health sciences (32) 32
medicin och hälsovetenskap (32) 32
clinical medicine (28) 28
klinisk medicin (28) 28
rheumatology (28) 28
reumatologi och inflammation (27) 27
rheumatology and autoimmunity (27) 27
humans (26) 26
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peptides, cyclic - immunology (4) 4
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arthritis, rheumatoid - epidemiology (3) 3
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autoimmune diseases (3) 3
biological specimen banks (3) 3
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classification (3) 3
cytokines (3) 3
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stroke - genetics (3) 3
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by Okada, Yukinori and Wu, Di and Trynka, Gosia and Raj, Towfique and Terao, Chikashi and Ikari, Katsunori and Kochi, Yuta and Ohmura, Koichiro and Suzuki, Akari and Yoshida, Shinji and Graham, Robert R and Manoharan, Arun and Ortmann, Ward and Bhangale, Tushar and Denny, Joshua C and Carroll, Robert J and Eyler, Anne E and Greenberg, Jeffrey D and Kremer, Joel M and Pappas, Dimitrios A and Jiang, Lei and Yin, Jian and Ye, Lingying and Su, Ding-Feng and Yang, Jian and Xie, Gang and Keystone, Ed and Westra, Harm-Jan and Esko, Tõnu and Metspalu, Anes and Zhou, Xuezhong and Gupta, Namrata and Mirel, Daniel and Stahl, Eli A and Diogo, Dorothée and Cui, Jing and Liao, Katherine and Guo, Michael H and Myouzen, Keiko and Kawaguchi, Takahisa and Coenen, Marieke J. H and van Riel, Piet L. C. M and van de Laar, Mart A. F. J and Guchelaar, Henk-Jan and Huizinga, Tom W. J and Dieudé, Philippe and Mariette, Xavier and Bridges, S. Louis and Zhernakova, Alexana and Toes, Rene E. M and Tak, Paul P and Miceli-Richard, Corinne and Bang, So-Young and Lee, Hye-Soon and Martin, Javier and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Rantapää-Dahlqvist, Solbritt and Arlestig, Lisbeth and Choi, Hyon K and Kamatani, Yoichiro and Galan, Pilar and Lathrop, Mark and Eyre, Steve and Bowes, John and Barton, Anne and de Vries, Niek and Moreland, Larry W and Criswell, Lindsey A and Karlson, Elizabeth W and Taniguchi, Atsuo and Yamada, Ryo and Kubo, Michiaki and Liu, Jun S and Bae, Sang-Cheol and Worthington, Jane and Padyukov, Leonid and Klareskog, Lars and Gregersen, Peter K and Raychaudhuri, Soumya and Stranger, Barbara E and de Jager, Philip L and Franke, Lude and Visscher, Peter M and Brown, Matthew A and Yamanaka, Hisashi and Mimori, Tsuneyo and Takahashi, Atsushi and Xu, Huji and Behrens, Timothy W and Siminovitch, Katherine A and Momohara, Shigeki and Matsuda, Fumihiko and Yamamoto, Kazuhiko and Plenge, Robert M and Lee, Annette and Martin, Paul and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and ... and RACI Consortium and GARNET Consortium and RACI consortium and GARNET consortium and the RACI consortium and the GARNET consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 376 - +
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets... 
RECEPTOR INHIBITION | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY | RISK | LOCI | IDENTIFICATION | TRAITS | GENOME-WIDE ASSOCIATION | RESOURCE | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Asian Continental Ancestry Group - genetics | Computational Biology | Male | Drug Repositioning | Molecular Targeted Therapy | Drug Discovery | Case-Control Studies | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - genetics | Animals | Arthritis, Rheumatoid - drug therapy | Alleles | Polymorphism, Single Nucleotide - genetics | Female | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - metabolism | Quantitative trait loci | Genome-wide association studies | Rheumatoid arthritis | Genetic research | Genetic aspects | Research | Human genetics | Disease | Hematology | Cytokines | Genes | Genomics | Genomes | Meta-analysis | Proteins | Confidence intervals | Hypotheses | Quality control | Epigenetics | Population | Genetics | Health risk assessment | Asians | Cancer | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Virtual screening | Klinisk medicin
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0164196 - e0164196
Objective The early diagnosis of rheumatoid arthritis (RA) is desirable to install treatment to prevent disease progression and joint destruction.... 
TRYPTOPHAN | COLLAGEN-INDUCED ARTHRITIS | MALDI-TOF MS | LYSOPHOSPHOLIPID RECEPTORS | SERIAL MEASUREMENTS | LYSOPHOSPHATIDYLCHOLINE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | BLOOD-DONORS | XANTHINE | Body Mass Index | Metabolomics | Carnitine - analysis | Area Under Curve | Humans | Middle Aged | Lysophosphatidylcholines - metabolism | Fatty Acids - analysis | Biomarkers - blood | Chromatography, High Pressure Liquid | Discriminant Analysis | Biological Specimen Banks | Least-Squares Analysis | Adult | Female | ROC Curve | Carnitine - analogs & derivatives | Lipids - analysis | Arthritis, Rheumatoid - diagnosis | Principal Component Analysis | Lysophosphatidylcholines - analysis | Tryptophan - analysis | Surveys | Autoimmunity | Rheumatoid factor | Metabolites | Physiological aspects | Antiarthritic agents | Tryptophan | Development and progression | Lipids | Arthritis | Liquid chromatography | Mass spectrometry | Oxidative stress | Profiling | Identification methods | Phospholipids | Immunology | Atherosclerosis | Oxidation | Life sciences | Bioindicators | Diagnosis | Public health | Autoantibodies | Medical treatment | Rheumatology | Rheumatic diseases | Mass spectroscopy | Inflammation | Metabolism | Fatty acids | Chromatography | Studies | Hospitals | Rheumatoid arthritis | Biomarkers | Sampling methods | Clinical medicine | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Naturvetenskap | Medical and Health Sciences | Kemi | Medicin och hälsovetenskap | Reumatologi och inflammation | Natural Sciences | Klinisk medicin | Chemical Sciences
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2012, Volume 71, Issue 6, pp. 825 - 829
Background Rheumatoid factors (RFs) and antibodies against cyclic citrullinated peptides (CCPs) of IgG, IgA and IgM isotype have been shown to precede disease... 
PROTEIN ANTIBODY | ASSOCIATIONS | METAANALYSIS | RISK-FACTOR | GENETICS | NATIONWIDE | SUSCEPTIBILITY | PTPN22 | POLYMORPHISM | RHEUMATOLOGY | SHARED EPITOPE ALLELES | Predictive Value of Tests | Rheumatoid Factor - blood | Immunoglobulin G - blood | Humans | Middle Aged | Risk Factors | Arthritis, Rheumatoid - epidemiology | Male | Peptides, Cyclic - immunology | Sweden - epidemiology | Immunoenzyme Techniques | Isoantibodies - blood | Arthritis, Rheumatoid - genetics | Immunoglobulin M - blood | Smoking - epidemiology | Sensitivity and Specificity | Immunoglobulin A - blood | Adult | Family | Female | Aged | Arthritis, Rheumatoid - immunology | Genetic Predisposition to Disease - epidemiology | Immunoassay | Rheumatoid factor | Usage | Care and treatment | Rheumatoid arthritis | Diagnosis | Health aspects | Studies | Immunoglobulins | Statistical analysis | Questionnaires | Heredity | Software | Twins | Age | Smoking | Index Medicus | Immunoglobulin M | Enzymes | Immunoglobulin G | Epitopes | Leukocytes | Enzyme immunoassay | Immunoglobulin A | Risk factors | Histocompatibility antigen HLA | citrulline | Immunoassays | Protein-tyrosine-phosphatase | Rheumatology and Autoimmunity | Clinical Medicine | familial studies | reumatologi | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | ACPA and RF | rheumatology | Klinisk medicin
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2015, Volume 74, Issue 3, pp. e13 - e13
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e66456 - e66456
Journal Article
Journal of Rheumatology, ISSN 0315-162X, 10/2015, Volume 42, Issue 10, pp. 1740 - 1745
Objective. Inflammasomes are intracellular protein complexes important for the production of proinflammatory cytokines. Studies have suggested that the NLRP3... 
Cardiovascular disease | Genetics | Inflammasomes | Rheumatoid arthritis | CARD8 RS2043211 | RS2043211 P.C10X | CROHNS-DISEASE | CORONARY | SUSCEPTIBILITY | ATHEROSCLEROSIS | RHEUMATOLOGY | GENETICS | CARDIOVASCULAR DISEASE | P.C10X POLYMORPHISM | RHEUMATOID ARTHRITIS | CARDIOVASCULAR-DISEASE | INFLAMMASOMES | ISCHEMIC-STROKE | EXPRESSION | Confidence Intervals | Age Distribution | Ischemic Attack, Transient - therapy | Ischemic Attack, Transient - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Male | Cardiovascular Diseases - genetics | Stroke - genetics | Incidence | Genetic Variation | Arthritis, Rheumatoid - drug therapy | Cardiovascular Diseases - epidemiology | Female | Stroke - epidemiology | Retrospective Studies | Arthritis, Rheumatoid - diagnosis | Stroke - therapy | Cardiovascular Diseases - diagnosis | Cross-Sectional Studies | Comorbidity | Arthritis, Rheumatoid - epidemiology | Genotype | Logistic Models | Sweden - epidemiology | Inflammasomes - genetics | Carrier Proteins - genetics | Ischemic Attack, Transient - epidemiology | Sex Distribution | Aged | Polymorphism, Single Nucleotide | Index Medicus | Clinical Medicine | RHEUMATOID ARTHRITIS; INFLAMMASOMES; GENETICS; CARDIOVASCULAR DISEASE | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article