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Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1316 - 1338
While a potential causal factor in Alzheimer's disease (AD), brain insulin resistance has not been demonstrated directly in that disorder. We provide such a... 
MEDICINE, RESEARCH & EXPERIMENTAL | SKELETAL-MUSCLE | RECEPTOR SUBSTRATE-1 IRS-1 | TYROSINE PHOSPHORYLATION | GLUCOSE-TRANSPORTER | A-BETA | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | TYPE-2 DIABETES-MELLITUS | GROWTH-FACTOR-I | AMYLOID-BETA OLIGOMERS | Insulin-Like Growth Factor I - pharmacology | Phosphorylation | Apolipoprotein E4 - genetics | Cerebellar Cortex - metabolism | Humans | Middle Aged | Cognition Disorders - metabolism | Male | Alzheimer Disease - pathology | Brain - metabolism | Cognition Disorders - etiology | Aged, 80 and over | Female | Insulin Receptor Substrate Proteins - genetics | Insulin Receptor Substrate Proteins - chemistry | Alzheimer Disease - psychology | Drug Resistance | Insulin - pharmacology | Signal Transduction | Insulin Receptor Substrate Proteins - physiology | Insulin Resistance | Hippocampus - pathology | Recombinant Proteins - pharmacology | Phosphoserine - metabolism | Diabetes Complications - complications | Brain - drug effects | Hippocampus - metabolism | Insulin - metabolism | Insulin-Like Growth Factor I - physiology | Cerebellar Cortex - pathology | Alzheimer Disease - metabolism | Brain - pathology | Glucose - metabolism | Aged | Protein Processing, Post-Translational | Care and treatment | Insulin resistance | Insulin-like growth factors | Cellular signal transduction | Diagnosis | Research | Properties | Alzheimer's disease | Index Medicus | Abridged Index Medicus
Journal Article
1976, Working papers in linguistics, Volume no. 21, 253 p. --
Book
1989, ISBN 9780275923303, xv, 326
Book
2000, Disease-a-month, Volume 46, no. 10., 651-723
Book
Annals of Internal Medicine, ISSN 0003-4819, 11/2013, Volume 159, Issue 10, pp. 688 - 697
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 16
Alzheimer’s disease (AD) is a leading cause of mortality in the elderly. While the coding change of APOE-ε4 is a key risk factor for late-onset AD and has been... 
Haplotypes | Brain | Chromatin | Pathogenesis | Cognitive ability | Health risks | Genomes | Gene expression | Risk analysis | Loci | Risk factors | Apolipoprotein E | Coding | Chromosomes | Alzheimer's disease | Conformation | Geriatrics
Journal Article
Annals of neurology, ISSN 0364-5134, 8/2018, Volume 84, Issue 2, pp. 168 - 175
Conventional parallel group randomized controlled clinical trials (RCT) in Alzheimer’s disease (AD) are too large, long, expensive and insensitive to clinical... 
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 06/2010, Volume 119, Issue 6, pp. 669 - 678
Journal Article
Annals of Neurology, ISSN 0364-5134, 08/2018, Volume 84, Issue 2, pp. 168 - 175
Journal Article
by Naj, Adam C and Jun, Gyungah and Beecham, Gary W and Wang, Li-San and Vardarajan, Badri Narayan and Buros, Jacqueline and Gallins, Paul J and Buxbaum, Joseph D and Jarvik, Gail P and Crane, Paul K and Larson, Eric B and Bird, Thomas D and Boeve, Bradley F and Graff-Radford, Neill R and De Jager, Philip L and Evans, Denis and Schneider, Julie A and Carrasquillo, Minerva M and Ertekin-Taner, Nilufer and Younkin, Steven G and Cruchaga, Carlos and Kauwe, John S. K and Nowotny, Petra and Kramer, Patricia and Hardy, John and Huentelman, Matthew J and Myers, Amanda J and Barmada, Michael M and Demirci, F Yesim and Baldwin, Clinton T and Green, Robert C and Rogaeva, Ekaterina and George-Hyslop, Peter St and Arnold, Steven E and Barber, Robert and Beach, Thomas and Bigio, Eileen H and Bowen, James D and Boxer, Adam and Burke, James R and Cairns, Nigel J and Carlson, Chris S and Carney, Regina M and Carroll, Steven L and Chui, Helena C and Clark, David G and Corneveaux, Jason and Cotman, Carl W and Cummings, Jeffrey L and Decarli, Charles and Dekosky, Steven T and Diaz-Arrastia, Ramon and Dick, Malcolm and Dickson, Dennis W and Ellis, William G and Faber, Kelley M and Fallon, Kenneth B and Farlow, Martin R and Ferris, Steven and Frosch, Matthew P and Galasko, Douglas R and Ganguli, Mary and Gearing, Marla and Geschwind, Daniel H and Ghetti, Bernardino and Gilbert, John R and Gilman, Sid and Giordani, Bruno and Glass, Jonathan D and Growdon, John H and Hamilton, Ronald L and Harrell, Lindy E and Head, Elizabeth and Honig, Lawrence S and Hulette, Christine M and Hyman, Bradley T and Jicha, Gregory A and Jin, Lee-Way and Johnson, Nancy and Karlawish, Jason and Karydas, Anna and Kaye, Jeffrey A and Kim, Ronald and Koo, Edward H and Kowall, Neil W and Lah, James J and Levey, Allan I and Lieberman, Andrew P and Lopez, Oscar L and MacK, Wendy J and Marson, Daniel C and Martiniuk, Frank and Mash, Deborah C and Masliah, Eliezer and McCormick, Wayne C and McCurry, Susan M and McDavid, Andrew N and McKee, Ann C and Mesulam, Marsel and Miller, Bruce L and ...
Nature Genetics, ISSN 1061-4036, 05/2011, Volume 43, Issue 5, pp. 436 - 443
Journal Article
PLOS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, pp. e0193707 - e0193707
Objective Alzheimer's disease (AD) is a complex neurodegenerative disease driven by multiple interacting pathophysiological processes that ultimately results... 
BLOOD BIOMARKERS | DEMENTIA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ACID-BINDING PROTEIN | BRAIN INSULIN-RESISTANCE | CSF | MARKERS | NEUROFILAMENT LIGHT | TAU | PATHOLOGY | Development and progression | Diagnosis | Biological markers | Health aspects | Alzheimer's disease | Cerebrospinal fluid proteins | Index Medicus
Journal Article
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
Journal Article