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Science, ISSN 0036-8075, 11/2011, Volume 334, Issue 6057, pp. 809 - 813
Phospholipase A₂ (PLA₂) enzymes are considered the primary source of arachidonic acid for cyclooxygenase (COX)-mediated biosynthesis of prostaglandins. Here,... 
Datasets | Brain | Enzymes | Prostaglandins | Cytokines | Neurodegenerative diseases | REPORTS | Eicosanoids | Lipids | Endocannabinoids | Vehicles | SYSTEM | INHIBITION | CYCLOOXYGENASE-2 | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | INJURY | LIPOPOLYSACCHARIDE | PHOSPHOLIPASE A | MICE | PARKINSONS-DISEASE | Cannabinoid Receptor Modulators - metabolism | Inflammation - pathology | Metabolomics | Arachidonic Acid - metabolism | Monoacylglycerol Lipases - antagonists & inhibitors | Monoacylglycerol Lipases - genetics | Brain - metabolism | Parkinsonian Disorders - metabolism | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Inflammation - metabolism | Neuroprotective Agents - pharmacology | Piperidines - pharmacology | Inflammation Mediators - pharmacology | Lung - metabolism | Cytokines - metabolism | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Phospholipases A2 - metabolism | Prostaglandins - biosynthesis | Glycerides - metabolism | Brain - drug effects | Hydrolysis | Animals | Parkinsonian Disorders - pathology | Eicosanoids - metabolism | Lipopolysaccharides - pharmacology | Brain - pathology | Mice | Cyclooxygenase 1 - metabolism | Benzodioxoles - pharmacology | Phospholipases A2 - genetics | Prostaglandins - metabolism | Physiological aspects | Inflammation | Research | Risk factors | Hydrology | Neurology | Inflammatory diseases | Animal models | Index Medicus
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 09/2009, Volume 330, Issue 3, pp. 902 - 910
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2009, Volume 106, Issue 48, pp. 20270 - 20275
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 09/2010, Volume 13, Issue 9, pp. 1113 - 1119
Prolonged exposure to drugs of abuse, such as cannabinoids and opioids, leads to pharmacological tolerance and receptor desensitization in the nervous system.... 
PRECIPITATED WITHDRAWAL | NEUROPATHIC PAIN | ACID AMIDE HYDROLASE | IN-VIVO | ANANDAMIDE | DELTA-TETRAHYDROCANNABINOL | CANNABINOID RECEPTOR ADAPTATION | MICE | RAT-BRAIN | NEUROSCIENCES | KNOCKOUT MOUSE | Cannabinoid Receptor Modulators - metabolism | Analgesics - pharmacology | Monoacylglycerol Lipases - antagonists & inhibitors | Neuronal Plasticity - drug effects | Male | Benzodioxoles - administration & dosage | Pain - metabolism | Brain - physiology | Monoacylglycerol Lipases - genetics | Enzyme Inhibitors - administration & dosage | Monoacylglycerol Lipases - metabolism | Neuronal Plasticity - physiology | Piperidines - pharmacology | Pain - drug therapy | Female | Models, Animal | Endocannabinoids | Amidohydrolases - metabolism | Synapses - drug effects | Piperidines - administration & dosage | Synapses - physiology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Analgesics - administration & dosage | Amidohydrolases - antagonists & inhibitors | Mice, Transgenic | Mice, Knockout | Brain - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Animals | Cannabinoid Receptor Modulators - antagonists & inhibitors | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Benzodioxoles - pharmacology | Complications and side effects | Cannabinoids | Drug tolerance | Physiological aspects | Neuropharmacology | Research | Properties | Drug receptors | Index Medicus
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 10/2013, Volume 229, Issue 4, p. 591
  Whereas cannabinoid CB^sub 1^ receptors have long been known to contribute to the rewarding effects and dependence liability of many drugs of abuse, recent... 
Neurons | Behavioral psychology | Rodents | Nicotine
Journal Article
Nature Neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 7, pp. 971 - 980
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2017, Volume 8, Issue 1, pp. 13958 - 13958
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous... 
MOLECULAR CHARACTERIZATION | INHIBITION | MULTIDISCIPLINARY SCIENCES | DIACYLGLYCEROL LIPASE-ALPHA | THERAPEUTIC TARGET | IN-VIVO | ANANDAMIDE | ENDOCANNABINOID SYSTEM | BIOLOGICAL EVALUATION | TRICYCLIC PYRAZOLES | HEPATIC ISCHEMIA/REPERFUSION INJURY | Index Medicus
Journal Article
Journal Article