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1. Nephroprotektive Effekte des SGLT2-Inhibitors Empagliflozin
by Artunc, Ferruh
Diabetes Aktuell, ISSN 1861-6089, 2018, Volume 16, Issue 7, p. 270
Journal Article
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2. Diabetes und Niere
by Artunc, Ferruh
Diabetes Aktuell, ISSN 1861-6089, 2018, Volume 16, Issue 7, p. 272
Journal Article
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3. Treating Shiga toxin induced haemolytic uraemic syndrome
by Ferruh Artunc
British Medical Journal, ISSN 0959-8146, 08/2012, Volume 345, Issue 7869, p. 7
  Shiga toxin induced hemolytic uremic syndrome occurs in a minority of patients alter infection with enterohemorrhagic Escherichia coil or Shigella spp. It is... 
Digestive system | Anemia | Infections | Toxins | Blood | Clinical outcomes
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4. Full Text Suicidal erythrocyte death in end-stage renal disease
by Abed, Majed and Artunc, Ferruh and Alzoubi, Kousi and Honisch, Sabina and Baumann, Dorothea and Föller, Michael and Lang, Florian
Journal of Molecular Medicine, ISSN 0946-2716, 8/2014, Volume 92, Issue 8, pp. 871 - 879
Anemia in end-stage renal disease (ESRD) results mainly from erythropoietin and iron deficiency. Anemia could be confounded, however, by accelerated clearance... 
Human Genetics | Eryptosis | Oxidative stress | End-stage renal disease | Biomedicine | Calcium | Ceramide abundance | Anemia | Internal Medicine | Molecular Medicine | Dialysis | Phosphatidylserine | MEDICINE, RESEARCH & EXPERIMENTAL | IRON | HYPORESPONSIVENESS | ERYTHROPOIESIS-STIMULATING AGENTS | GENETICS & HEREDITY | CHRONIC KIDNEY-DISEASE | EXPOSURE | Reactive Oxygen Species - metabolism | Oxidative Stress | Calcium - metabolism | Phosphatidylserines - pharmacology | Humans | Middle Aged | Male | Case-Control Studies | Ceramides - biosynthesis | Kidney Failure, Chronic - pathology | Cell Death | Aged, 80 and over | Erythrocytes - pathology | Adult | Female | Kidney Failure, Chronic - diagnosis | Erythrocytes - drug effects | Kidney Failure, Chronic - metabolism | Kidney Failure, Chronic - therapy | Annexin A5 - metabolism | Intracellular Space - metabolism | Erythrocytes - metabolism | Aged | Apoptosis | Kidney Failure, Chronic - etiology | Complications and side effects | Suicidal behavior | Chronic kidney failure | Patient outcomes | Fluorescein | Development and progression | Research | Health aspects
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5. Paricalcitol: Potentere VDRAktivierung bei geringerem Hypercalcämie-Risiko
by Artunc, Ferruh
Nieren- und Hochdruckkrankheiten, ISSN 0300-5224, 12/2014, Volume 43, Issue 12, pp. 529 - 531
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6. Full Text Reduced Erythrocyte Survival in Uremic Patients Under Hemodialysis or Peritoneal Dialysis
by Bissinger, Rosi and Artunc, Ferruh and Qadri, Syed M and Lang, Florian
Kidney and Blood Pressure Research, ISSN 1420-4096, 12/2016, Volume 41, Issue 6, pp. 966 - 977
Background/Aims: Recent observations in end-stage renal disease (ESRD)-patients on hemodialysis revealed that anemia is, in part, due to stimulated suicidal... 
Original Paper | End-stage renal disease | Eryptosis | Anemia | Hemodialysis | Peritoneal dialysis | UNITED-STATES | OXIDATIVE STRESS | PHYSIOLOGY | INDUCED SUICIDAL DEATH | CATION CHANNELS | ERYTHROPOIESIS-STIMULATING AGENTS | IN-VITRO | UROLOGY & NEPHROLOGY | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | PHOSPHATIDYLSERINE EXPOSURE | CHRONIC KIDNEY-DISEASE | Reactive Oxygen Species | Oxidative Stress | Erythropoietin - therapeutic use | Humans | Middle Aged | Phosphatidylserines - metabolism | Male | Peritoneal Dialysis - adverse effects | Renal Insufficiency - therapy | Uremia - blood | Cell Death | Renal Dialysis - adverse effects | Ceramides | Erythrocytes - pathology | Adult | Female | Renal Insufficiency - blood | Apoptosis
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7. Full Text The impact of insulin resistance on the kidney and vasculature
by Artunc, Ferruh and Schleicher, Erwin and Weigert, Cora and Fritsche, Andreas and Stefan, Norbert and Häring, Hans-Ulrich
Nature Reviews Nephrology, ISSN 1759-5061, 12/2016, Volume 12, Issue 12, pp. 721 - 737
Insulin resistance is a systemic disorder that affects many organs and insulin-regulated pathways. The disorder is characterized by a reduced action of insulin... 
GLOMERULAR-FILTRATION-RATE | LIFE-STYLE INTERVENTION | FETUIN-A LEVELS | NONALCOHOLIC FATTY LIVER | NITRIC-OXIDE SYNTHASE | ALPHA-HEREMANS-SCHMID GLYCOPROTEIN/FETUIN-A | UROLOGY & NEPHROLOGY | IMPAIRED GLUCOSE-TOLERANCE | COTRANSPORTER 2 INHIBITION | PERIVASCULAR ADIPOSE-TISSUE | METABOLIC SYNDROME SUBJECTS | Adipose Tissue - physiology | Kidney - blood supply | Receptor Cross-Talk | Signal Transduction | Humans | Kidney Tubules - physiology | Metabolic Syndrome - therapy | Sodium Chloride, Dietary | Kidney - metabolism | Animals | Insulin Resistance - physiology | Endothelium - physiology | Disease Models, Animal
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8. Mineralocorticoid and SGK1-sensitive inflammation and tissue fibrosis
by Artunc, Ferruh and Lang, Florian
Nephron - Physiology, ISSN 1660-2137, 04/2014, Volume 128, Issue 1-2, pp. 35 - 39
Effects of mineralocorticoids are not restricted to regulation of epithelial salt transport, extracellular volume and blood pressure; mineralocorticoids also... 
Connective tissue growth factor | TGF-β | SGK1 | Mineralocorticoid receptor | T H 17 cells | SALT HYPERTENSIVE-RATS | ALDOSTERONE ACTION | METABOLIC SYNDROME | RECEPTOR ANTAGONISTS | GLUCOCORTICOID-INDUCIBLE KINASE | PATHOGENIC T(H)17 CELLS | HEART-FAILURE | VASCULAR FUNCTION | CARDIOVASCULAR-DISEASE | UROLOGY & NEPHROLOGY | CARDIAC FIBROSIS | Up-Regulation | Th17 Cells - physiology | Animals | Protein-Serine-Threonine Kinases - physiology | Fibrosis - etiology | Transforming Growth Factor beta - physiology | Rats | Mice | Inflammation - etiology | Mineralocorticoids - physiology | Receptors, Mineralocorticoid - physiology
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9. Full Text Serum erythropoietin concentrations and responses to anaemia in patients with or without chronic kidney disease
by Artunc, Ferruh and Risler, Teut
Nephrology Dialysis Transplantation, ISSN 0931-0509, 10/2007, Volume 22, Issue 10, pp. 2900 - 2908
Background. Renal anaemia is caused by a relative erythropoietin (EPO) deficiency. Due to difficult interpretation of serum EPO concentrations adapted to... 
Response | Diagnostic value | Renal anaemia | Erythropoietin | CKD | response | LIVER | UROLOGY & NEPHROLOGY | diagnostic value | CANCER | renal anaemia | DIALYSIS | erythropoietin | RENAL-INSUFFICIENCY | TRANSPLANTATION | Polycystic Kidney Diseases - metabolism | Humans | Middle Aged | Hemoglobins - metabolism | Male | Erythropoietin - blood | Chemistry, Clinical - methods | Regression Analysis | Anemia - complications | Anemia - drug therapy | Kidney Failure, Chronic - blood | Models, Biological | Kidney Failure, Chronic - complications | Adult | Female | Aged | Retrospective Studies
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10. Full Text Proteasuria—The impact of active urinary proteases on sodium retention in nephrotic syndrome
by Artunc, Ferruh and Wörn, Matthias and Schork, Anja and Bohnert, Bernhard N
Acta Physiologica, ISSN 1748-1708, 04/2019, Volume 225, Issue 4, pp. e13249 - n/a
Sodium retention and extracellular volume expansion are typical features of patients with nephrotic syndrome. In recent years, from in vitro data, endoluminal... 
aprotinin | proteinuria | proteasuria | ENaC | serine protease | nephrotic syndrome | proteolysis | PHYSIOLOGY | INCREASED EXPRESSION | EPITHELIAL NA+ CHANNEL | PROTEOLYTIC ACTIVATION | ANGIOTENSIN-ALDOSTERONE SYSTEM | AMILORIDE | COLLECTING DUCT | EDEMA FORMATION | PLASMIN | GAMMA-SUBUNIT | Aprotinin | Nephrotic syndrome | Proteases | Proteolysis | Urine | Edema | Sodium | Serine | Avidity | Serine proteinase | Retention | Health risk assessment
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11. Full Text FP278CHARACTERIZATION AND QUANTIFICATION OF PROTEASURIA IN NEPHROTIC SYNDROME
by Artunc, Ferruh and Alenazi, Fawza and Kalbacher, Hubert and Wörn, Matthias
Nephrology Dialysis Transplantation, ISSN 0931-0509, 05/2018, Volume 33, Issue suppl_1, pp. i125 - i125
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12. Full Text Eryptosis - the Neglected Cause of Anemia in End Stage Renal Disease
by Lang, Florian and Bissinger, Rosi and Abed, Majed and Artunc, Ferruh
Kidney and Blood Pressure Research, ISSN 1420-4096, 12/2017, Volume 42, Issue 4, pp. 749 - 760
End stage renal disease (ESRD) invariably leads to anemia which has been mainly attributed to compromised release of erythropoietin from the defective kidneys... 
Review | Eryptosis | Microcirculation | Uremic toxins | End-stage renal disease (ESRD) | Cell membrane scrambling | Cell shrinkage | OXIDATIVE STRESS | PHYSIOLOGY | IRON | SUICIDAL ERYTHROCYTE DEATH | ENERGY DEPLETION | HYPORESPONSIVENESS | ERYTHROPOIESIS-STIMULATING AGENTS | BAY 11-7082 | UROLOGY & NEPHROLOGY | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | PHOSPHATIDYLSERINE EXPOSURE | CHRONIC KIDNEY-DISEASE | Erythropoiesis | Signal Transduction | Humans | Erythrocytes - metabolism | Kidney Failure, Chronic - complications | Anemia - etiology | Eryptosis - drug effects | Oxidative stress | GTP-binding protein | Erythropoietin | Calcium | Syngeneic grafts | Indole | Erythrocytes | Mental health | Impairment | Stimulation | Kinases | Macrophages | Cell surface | Cyclin-dependent kinase 4 | Blood | Peritoneal dialysis | Proteins | Cyclin-dependent kinase | Acrolein | Stimulators | Red blood cells | Allografts | Casein | Cyclic GMP | Ceramide | Janus kinase | Inhibition | Xenobiotics | Tyrosine | Translocation | Kidneys | AMP | Anemia | p21-activated kinase | Calpain | Cell membranes | Shrinkage | Blood circulation | Toxins | Kidney diseases | Acetic acid | Pyruvaldehyde | Calcium ions
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13. Full Text Performance of a novel high sensitivity cardiac troponin I assay in asymptomatic hemodialysis patients – evidence for sex-specific differences
by Artunc, Ferruh and Haag, Stefanie and Friedrich, Björn and Mueller, Christian and Häring, Hans-Ulrich and Peter, Andreas
Clinical Chemistry and Laboratory Medicine (CCLM), ISSN 1434-6621, 07/2019, Volume 57, Issue 8, pp. 1261 - 1270
Background: High sensitivity assays for the determination of cardiac troponin I (cTnI) are able to reliably measure cTnI far below the 99th percentile of... 
hemodialysis | high sensitivity | sex-specific | troponin I | prognosis | POPULATION | PREDICTIVE-VALUE | ACUTE CORONARY SYNDROME | PROGNOSTIC VALUE | BIOMARKERS | FLUID | 99TH PERCENTILE | MEDICAL LABORATORY TECHNOLOGY | STAGE RENAL-DISEASE | Women | Renal function | Hemodialysis | Mortality | Sex | Coronary artery disease | Sensitivity | Accuracy | Troponin | Troponin I | Ischemia | Calcium-binding protein | Men | Death | Dialysis | Heart diseases
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14. Full Text FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair
by Zhou, Weibin and Otto, Edgar A and Cluckey, Andrew and Airik, Rannar and Hurd, Toby W and Chaki, Moumita and Diaz, Katrina and Lach, Francis P and Bennett, Geoffrey R and Gee, Heon Yung and Ghosh, Amiya K and Natarajan, Sivakumar and Thongthip, Supawat and Veturi, Uma and Allen, Susan J and Janssen, Sabine and Ramaswami, Gokul and Dixon, Joanne and Burkhalter, Felix and Spoendlin, Martin and Moch, Holger and Mihatsch, Michael J and Verine, Jerome and Reade, Richard and Soliman, Hany and Godin, Michel and Kiss, Denes and Monga, Guido and Mazzucco, Gianna and Amann, Kerstin and Artunc, Ferruh and Newland, Ronald C and Wiech, Thorsten and Zschiedrich, Stefan and Huber, Tobias B and Friedl, Andreas and Slaats, Gisela G and Joles, Jaap A and Goldschmeding, Roel and Washburn, Joseph and Giles, Rachel H and Levy, Shawn and Smogorzewska, Agata and Hildebrandt, Friedhelm
Nature Genetics, ISSN 1061-4036, 08/2012, Volume 44, Issue 8, pp. 910 - 915
Chronic kidney disease (CKD) represents a major health burden(1). Its central feature of renal fibrosis is not well understood. By exome sequencing, we... 
KIAA1018/FAN1 | ZEBRAFISH | ENTITY | PATHWAY | INVERSIN | CYSTIC-DISEASE | GENETICS & HEREDITY | HOODED HYPERTENSIVE-RATS | FANCONI-ANEMIA | MULTIPOINT LINKAGE ANALYSIS | NUCLEASE | Cell Line | Nephritis, Interstitial - complications | Fanconi Anemia Complementation Group D2 Protein - genetics | Renal Insufficiency, Chronic - etiology | Humans | Zebrafish - abnormalities | DNA Repair - genetics | Genes, Recessive | Genetic Complementation Test | Zebrafish - genetics | Gene Knockdown Techniques | Renal Insufficiency, Chronic - metabolism | Animals | Nephritis, Interstitial - metabolism | Nephritis, Interstitial - pathology | Nephritis, Interstitial - genetics | Renal Insufficiency, Chronic - genetics | DNA Damage | Exodeoxyribonucleases - genetics | Mutation | Chronic kidney failure | Gene mutations | Genetic aspects | Research | DNA repair | Health aspects | Risk factors | Proteins | Studies | Genotype & phenotype | Anemia | Genomes | Diabetes | Kidney diseases | Charitable foundations | Chromosomes | Deoxyribonucleic acid--DNA | Defects
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15. Full Text Prognostic value and link to atrial fibrillation of soluble klotho and FGF23 in hemodialysis patients
by Nowak, Albina and Friedrich, Björn and Artunc, Ferruh and Serra, Andreas L and Breidthardt, Tobias and Twerenbold, Raphael and Peter, Myriam and Mueller, Christian
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e100688
Deranged calcium-phosphate metabolism contributes to the burden of morbidity and mortality in dialysis patients. This study aimed to assess the association of... 
MORTALITY | RISK-FACTORS | MYOCARDIAL-INFARCTION | MULTIDISCIPLINARY SCIENCES | GROWTH-FACTOR 23 | MEDIA CALCIFICATION | CHRONIC KIDNEY-DISEASE | SECRETED KLOTHO | STAGE RENAL-DISEASE | ARTERY CALCIFICATION | DIALYSIS | Phosphates | Prognosis | Hemodialysis | Analysis | Abnormalities | Physiological aspects | Fibroblast growth factors | Health aspects | Muscle contraction | Plasma | Fibroblast growth factor | Nephrology | Transplants & implants | Calcium | Fibroblast growth factor 23 | Laboratories | Calcium metabolism | Cardiovascular disease | Peritoneal dialysis | Proteins | Fibrillation | Fibroblasts | Cardiology | Growth factors | Age | Internal medicine | Blood & organ donations | Mortality | Regression analysis | Metabolism | Patients | Morbidity | Calcium phosphates | Hospitals | Klotho protein | Coronary vessels | Calcification | Dialysis | Kidney diseases | Health risk assessment | Endocrinology
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16. Full Text Reversal of Cardiovascular Risk Factors in Patients with End-Stage-Renal-Disease
by Artunc, Ferruh
Turkish Nephrology Dialysis Transplantation, ISSN 1300-7718, 01/2012, Volume 21, Issue 1, pp. 10 - 20
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17. Full Text Treating Shiga toxin induced haemolytic uraemic syndrome: Clinical lessons from a recent outbreak of Escherichia coli O104:H4 in Germany
by Ferruh Artunc
BMJ: British Medical Journal, ISSN 0959-8138, 8/2012, Volume 345, Issue 7869, pp. 7 - 7
Nervous system diseases | EDITORIALS | Antibiotics | Escherichia coli | Disease outbreaks | Sprains and strains | Shiga toxins | Plasmapheresis
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18. Full Text Sensitive Troponins - Which Suits Better for Hemodialysis Patients? Associated Factors and Prediction of Mortality
by Artunc, Ferruh and Mueller, Christian and Breidthardt, Tobias and Twerenbold, Raphael and Peter, Andreas and Thamer, Claus and Weyrich, Peter and Haering, Hans-Ulrich and Friedrich, Bjoern
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47610
Background: In hemodialysis patients, elevated plasma troponin concentrations are a common finding that has even increased with the advent of newly developed... 
CARDIAC TROPONIN | I ASSAYS | MYOCARDIAL-INFARCTION | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | DEATH | LEFT-VENTRICULAR MASS | RELEASE | CHRONIC KIDNEY-DISEASE | ASYMPTOMATIC PATIENTS | STAGE RENAL-DISEASE | Myocardial Infarction - blood | Prognosis | Cross-Sectional Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Renal Dialysis - methods | Male | Troponin I - blood | Troponin T - blood | Kidney Failure, Chronic - blood | Renal Dialysis - mortality | Female | Aged | Diagnosis | Research | Health aspects | Heart attack | Risk factors | Hemodialysis patients | Heart | Plasma | Diuresis | Nephrology | Hemodialysis | Assaying | Regression models | Ischemia | Calcium-binding protein | Blood pressure | Workloads | Cardiology | Heart diseases | Heart failure | Internal medicine | Mortality | Regression analysis | Patients | Troponin T | Medicine | Troponin | Troponin I | Medical prognosis | Coronary vessels | Predictions | Dialysis | Kidney diseases | Endocrinology
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