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1. Full Text Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
by Jha, Abhishek K and Huang, Stanley Ching-Cheng and Sergushichev, Alexey and Lampropoulou, Vicky and Ivanova, Yulia and Loginicheva, Ekaterina and Chmielewski, Karina and Stewart, Kelly M and Ashall, Juliet and Everts, Bart and Pearce, Edward J and Driggers, Edward M and Artyomov, Maxim N
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 419 - 430
Life Sciences & Biomedicine | Immunology | Science & Technology | Glutamine - deficiency | Aspartic Acid - immunology | Argininosuccinic Acid - immunology | Mitochondria - immunology | Chemokine CCL22 - immunology | Metabolic Networks and Pathways - immunology | Mitochondria - genetics | Argininosuccinic Acid - metabolism | Gene Regulatory Networks - immunology | Isocitrate Dehydrogenase - immunology | Macrophages - immunology | Uridine Diphosphate N-Acetylglucosamine - metabolism | Nitric Oxide - immunology | Macrophages - classification | Aspartate Aminotransferase, Mitochondrial - immunology | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Isocitrate Dehydrogenase - genetics | Glycosylation | Mitochondria - metabolism | Macrophages - cytology | Immunity, Innate | Citric Acid Cycle | Uridine Diphosphate N-Acetylglucosamine - immunology | Chemokine CCL22 - genetics | Macrophages - metabolism | Metabolic Networks and Pathways - genetics | Animals | Interleukin-6 - immunology | Transcription, Genetic - immunology | Aspartic Acid - metabolism | Mice | Aspartate Aminotransferase, Mitochondrial - genetics | Nitric Oxide - metabolism | Enzymes | Tracers (Biology) | Analysis | Nitric oxide | Physiological aspects | Aspartate | Genetic aspects | Genetic transcription | Macrophages | Glutamine | Metabolites | Rodents | Scientific imaging | Metabolism | Labeling | Mass spectrometry | Index Medicus
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2. Full Text Tumor neoantigens: Building a framework for personalized cancer immunotherapy
by Gubin, Matthew M and Artyomov, Maxim N and Mardis, Elaine R and Schreiber, Robert D
The Journal of clinical investigation, ISSN 0021-9738, 09/2015, Volume 125, Issue 9, pp. 3413 - 3421
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Antigens, Neoplasm - genetics | Immunotherapy - methods | Immunity, Cellular - genetics | Antigens, Neoplasm - immunology | Humans | Epitopes - genetics | Epitopes - immunology | Neoplasms - therapy | Immunity, Cellular - drug effects | Neoplasms - genetics | Antigens, Neoplasm - therapeutic use | Epigenesis, Genetic - immunology | Neoplasms - immunology | T-Lymphocytes - immunology | Epigenesis, Genetic - drug effects | High-Throughput Nucleotide Sequencing | Mutation | Neoplasms - pathology | Epitopes - therapeutic use | Precision Medicine - methods | Antigens | T cell receptors | Immunotherapy | Index Medicus | Abridged Index Medicus | Review Series
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3. Full Text Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function
by Wu, Duojiao and Sanin, David E and Everts, Bart and Chen, Qiongyu and Qiu, Jing and Buck, Michael D and Patterson, Annette and Smith, Amber M and Chang, Chih-Hao and Liu, Zhiping and Artyomov, Maxim N and Pearce, Erika L and Cella, Marina and Pearce, Edward J
Immunity (Cambridge, Mass.), ISSN 1074-7613, 06/2016, Volume 44, Issue 6, pp. 1325 - 1336
Life Sciences & Biomedicine | Immunology | Science & Technology | Lymphocytic choriomeningitis virus - immunology | CpG Islands - immunology | Oligodeoxyribonucleotides - immunology | Signal Transduction | Dendritic Cells - immunology | Enoyl-CoA Hydratase - metabolism | Mice, Inbred C57BL | 3-Hydroxyacyl CoA Dehydrogenases - metabolism | Cells, Cultured | Gene Expression Regulation | Oxidative Phosphorylation | Lipid Metabolism | Lymphocytic Choriomeningitis - immunology | Immunity | Carbon-Carbon Double Bond Isomerases - metabolism | Receptors, Interferon - metabolism | Racemases and Epimerases - metabolism | Animals | Acetyl-CoA C-Acyltransferase - metabolism | Interferon Type I - metabolism | Cell Differentiation | Mice | PPAR alpha - metabolism | Toll-Like Receptor 9 - metabolism | Epigenetic inheritance | Medical colleges | Synthesis | Dendritic cells | Physiological aspects | Interferon | Biological response modifiers | Health aspects | Fatty acids | Biomedical engineering | Antigens | Scholarships & fellowships | Lipids | Tumor necrosis factor-TNF | Grants | Metabolism | Gene expression | Index Medicus
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4. Full Text Itaconate: the poster child of metabolic reprogramming in macrophage function
by O’Neill, Luke A. J and Artyomov, Maxim N
Nature reviews. Immunology, ISSN 1474-1733, 05/2019, Volume 19, Issue 5, pp. 273 - 281
Life Sciences & Biomedicine | Immunology | Science & Technology | Animals | Oxidation-Reduction | Macrophage Activation - immunology | Humans | Succinates - immunology | Inflammation - immunology | Interferon Type I - immunology | Child | Macrophages - immunology | Virus diseases | Immune response | Metabolites | Physiological aspects | Interferon | Macrophages | Health aspects | Nuclear reprogramming | Immunological research | Tricarboxylic acid cycle | Cell activation | Oxidative metabolism | Tumorigenesis | Inflammation | Metabolism | Immunity | Tumors | Index Medicus
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5. Full Text Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas
by Campbell, Joshua D and Alexandrov, Anton and Kim, Jaegil and Wala, Jeremiah and Berger, Alice H and Pedamallu, Chandra Sekhar and Shukla, Sachet A and Guo, Guangwu and Brooks, Angela N and Murray, Bradley A and Imielinski, Marcin and Hu, Xin and Ling, Shiyun and Akbani, Rehan and Rosenberg, Mara and Cibulskis, Carrie and Ramachandran, Aruna and Collisson, Eric A and Kwiatkowski, David J and Lawrence, Michael S and Weinstein, John N and Verhaak, Roel G.W and Wu, Catherine J and Hammerman, Peter S and Cherniack, Andrew D and Getz, Gad and Artyomov, Maxim N and Schreiber, Robert and Govindan, Ramaswamy and Meyerson, Matthew and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Nature genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 607 - 616
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Adenocarcinoma | Usage | Squamous cell carcinoma | Nucleotide sequencing | Risk factors | DNA sequencing | Genomics | Lung cancer | Colleges & universities | Quality control | Defense contracts | Genomes | Mutation | Grants | Signatures | Tumors | Smoking | Index Medicus
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6. Full Text Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
by Lampropoulou, Vicky and Sergushichev, Alexey and Bambouskova, Monika and Nair, Sharmila and Vincent, Emma E and Loginicheva, Ekaterina and Cervantes-Barragan, Luisa and Ma, Xiucui and Huang, Stanley Ching-Cheng and Griss, Takla and Weinheimer, Carla J and Khader, Shabaana and Randolph, Gwendalyn J and Pearce, Edward J and Jones, Russell G and Diwan, Abhinav and Diamond, Michael S and Artyomov, Maxim N
Cell metabolism, ISSN 1550-4131, 07/2016, Volume 24, Issue 1, pp. 158 - 166
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Inflammation - pathology | Reactive Oxygen Species - metabolism | Macrophages - pathology | Reperfusion Injury - pathology | Reperfusion Injury - enzymology | Succinate Dehydrogenase - antagonists & inhibitors | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Macrophages - enzymology | Macrophages - metabolism | Animals | Succinic Acid - metabolism | Cell Respiration - drug effects | Lipopolysaccharides - pharmacology | Female | Macrophages - drug effects | Succinate Dehydrogenase - metabolism | Macrophage Activation - drug effects | Inflammation - enzymology | Succinates - pharmacology | Medical colleges | Inflammation | Metabolites | Macrophages | Index Medicus
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7. Full Text Integrating immunometabolism and macrophage diversity
by Artyomov, Maxim N and Sergushichev, Alexey and Schilling, Joel D., M.D., Ph.D
Seminars in immunology, ISSN 1044-5323, 2016, Volume 28, Issue 5, pp. 417 - 424
Allergy and Immunology | Glycolysis | Mitochondria | Inflammation | Metabolism | Nitric oxide | Life Sciences & Biomedicine | Immunology | Science & Technology | Macrophage Activation - genetics | Immunomodulation | Macrophage Activation - immunology | Humans | Gene Expression Regulation | Macrophages - cytology | Organ Specificity - immunology | Organ Specificity - genetics | Macrophages - metabolism | Phenotype | Animals | Energy Metabolism | Metabolic Networks and Pathways | Macrophages - immunology | Macrophages | Medical colleges | Index Medicus | nitric oxide | metabolism | mitochondria | glycolysis
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8. Full Text Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
by Gubin, Matthew M and Zhang, Xiuli and Schuster, Heiko and Caron, Etienne and Ward, Jeffrey P and Noguchi, Takuro and Ivanova, Yulia and Hundal, Jasreet and Arthur, Cora D and Krebber, Willem-Jan and Mulder, Gwenn E and Toebes, Mireille and Vesely, Matthew D and Lam, Samuel S.K and Korman, Alan J and Allison, James P and Freeman, Gordon J and Sharpe, Arlene H and Pearce, Erika L and Schumacher, Ton N and Aebersold, Ruedi and Rammensee, Hans-Georg and Melief, Cornelis J.M and Mardis, Elaine R and Gillanders, William E and Artyomov, Maxim N and Schreiber, Robert D
Nature (London), ISSN 0028-0836, 11/2014, Volume 515, Issue 7528, pp. 577 - 581
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antigens, Neoplasm - genetics | Sarcoma - immunology | Antigens, Neoplasm - immunology | Antibodies, Monoclonal - therapeutic use | Male | Vaccines, Synthetic - therapeutic use | Epitopes - genetics | Sarcoma - therapy | Cancer Vaccines - therapeutic use | Animals | Immunotherapy | Mice | CD8-Positive T-Lymphocytes - immunology | Cell Cycle Checkpoints - immunology | Care and treatment | Sarcoma | Analysis | Development and progression | Drug therapy | Health aspects | Antigenic determinants | Cancer | Antigens | Peptides | Lymphocytes | Mutation | Tumors | Index Medicus
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9. Full Text Immunometabolism in the Single-Cell Era
by Artyomov, Maxim N and Van den Bossche, Jan
Cell metabolism, ISSN 1550-4131, 11/2020, Volume 32, Issue 5, pp. 710 - 725
single-cell RNA-sequencing | immunometabolism | spatiotemporal | flow cytometry | metabolism | CyTOF mass cytometry | next-generation immunometabolism | immunology | Molecular Biology | Physiology | Cell Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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