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Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 419 - 430
Macrophage polarization involves a coordinated metabolic and transcriptional rewiring that is only partially understood. By using an integrated high-throughput... 
IMMUNITY | CELLS | ACTIVATION | INFLAMMATION | NITRIC-OXIDE | INNATE | GLYCOSYLATION | IMMUNOLOGY | Glutamine - deficiency | Aspartic Acid - immunology | Argininosuccinic Acid - immunology | Mitochondria - immunology | Chemokine CCL22 - immunology | Metabolic Networks and Pathways - immunology | Mitochondria - genetics | Argininosuccinic Acid - metabolism | Gene Regulatory Networks - immunology | Isocitrate Dehydrogenase - immunology | Macrophages - immunology | Uridine Diphosphate N-Acetylglucosamine - metabolism | Nitric Oxide - immunology | Macrophages - classification | Aspartate Aminotransferase, Mitochondrial - immunology | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Isocitrate Dehydrogenase - genetics | Glycosylation | Mitochondria - metabolism | Macrophages - cytology | Immunity, Innate | Citric Acid Cycle | Uridine Diphosphate N-Acetylglucosamine - immunology | Chemokine CCL22 - genetics | Macrophages - metabolism | Metabolic Networks and Pathways - genetics | Animals | Interleukin-6 - immunology | Transcription, Genetic - immunology | Aspartic Acid - metabolism | Mice | Aspartate Aminotransferase, Mitochondrial - genetics | Nitric Oxide - metabolism | Enzymes | Tracers (Biology) | Analysis | Nitric oxide | Physiological aspects | Aspartate | Genetic aspects | Genetic transcription | Macrophages | Glutamine | Metabolites | Rodents | Scientific imaging | Metabolism | Labeling | Mass spectrometry
Journal Article
Nature immunology, ISSN 1529-2908, 2014, Volume 15, Issue 4, pp. 323 - +
The ligation of Toll-like receptors (TLRs) leads to rapid activation of dendritic cells (DCs). However, the metabolic requirements that support this process... 
TRANSFORMATION | IMMUNE-RESPONSE | METABOLISM | MEMORY | PHOSPHORYLATION | MACROPHAGES | NITRIC-OXIDE | AKT | ACCUMULATION | IMMUNOLOGY | BINDING
Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7528, pp. 577 - 581
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 05/2019, Volume 19, Issue 5, pp. 273 - 281
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 607 - 616
Journal Article
Physical Review Letters, ISSN 0031-9007, 04/2009, Volume 102, Issue 14
Journal Article
Cell, ISSN 0092-8674, 08/2017, Volume 170, Issue 4, pp. 649 - 663.e13
Journal Article
eLife, ISSN 2050-084X, 04/2014, Volume 2014, Issue 3, p. e01659
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2209 - 16
Changes in bulk transcriptional profiles of heterogeneous samples often reflect changes in proportions of individual cell types. Several robust techniques have... 
HEAD | EXPRESSION | MULTIDISCIPLINARY SCIENCES | Deconvolution | Composition |