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Journal of Clinical Investigation, ISSN 0021-9738, 06/2012, Volume 122, Issue 6, pp. 2221 - 2233
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2013, Volume 45, Issue 3, pp. 279 - 284
Journal Article
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 8, pp. 864 - 871
Journal Article
Journal Article
Monoclonal antibodies in immunodiagnosis and immunotherapy, 04/2019, Volume 38, Issue 2, pp. 38 - 59
Cytotoxic NK/CD8 T cells interact with MHC-I ligands on tumor cells through either activating or inhibiting receptors. One of the inhibitory receptors is... 
Cell proliferation | Toxicity | CD8 antigen | Clinical trials | Cytotoxicity | Lymphocytes T | Helices | Proteins | NKG2 antigen | Receptors | Lymphocytes | Immunotherapy | Natural killer cells | Medical research | Cell survival | Tumor cells | Epitopes | CD4 antigen | White blood cells | Major histocompatibility complex | Monoclonal antibodies | Ligands | Histocompatibility antigen HLA | Cancer | Tumors
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 804 - 813
Purpose: Immunotherapy of high-risk neuroblastoma using the anti-GD2 antibody dinutuximab induces antibody-dependent cell-mediated cytotoxicity (ADCC).... 
BREAST-CANCER | RECEPTOR KINASE INHIBITOR | TGF-BETA | GAMMA PRODUCTION | METASTASIS | ONCOLOGY | GROWTH | TUMOR-TISSUE | ANTITUMOR-ACTIVITY | EX-VIVO | CYTOTOXICITY | Receptor, Transforming Growth Factor-beta Type I | Receptors, Transforming Growth Factor beta - genetics | Humans | Neoplasm Proteins - physiology | Male | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | Receptors, Transforming Growth Factor beta - physiology | Smad2 Protein - antagonists & inhibitors | Quinolines - pharmacology | RNA, Messenger - biosynthesis | Protein Processing, Post-Translational - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Phosphorylation - drug effects | Neuroblastoma - pathology | Transforming Growth Factor beta1 - biosynthesis | Pyrazoles - pharmacology | Killer Cells, Natural - transplantation | Specific Pathogen-Free Organisms | Immunotherapy, Adoptive | Protein-Serine-Threonine Kinases - physiology | Antibodies, Monoclonal - pharmacology | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Smad2 Protein - metabolism | Transforming Growth Factor beta1 - genetics | Transforming Growth Factor beta1 - physiology | Antineoplastic Agents, Immunological - pharmacology | Drug Synergism | Protein-Serine-Threonine Kinases - biosynthesis | Xenograft Model Antitumor Assays | Receptors, Transforming Growth Factor beta - biosynthesis | Animals | RNA, Neoplasm - biosynthesis | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Cell Line, Tumor | RNA, Neoplasm - genetics | Mice, Inbred NOD | Mice | Neuroblastoma - metabolism | Cytotoxicity, Immunologic | Phosphorylation | Smad protein | Severe combined immunodeficiency | Toxicity | Cytotoxicity | Activation | Neuroblastoma | Blood | Neuroblastoma cells | NKG2 antigen | Receptors | Smad2 protein | Immunotherapy | Xenografts | Bone marrow | Plasmas | CD226 antigen | Natural killer cells | Perforin | Antibody-dependent cell-mediated cytotoxicity | Cell survival | Transforming growth factor-b1 | Risk groups | Gene expression | Experimental design | Cell lines | TRAIL protein | Bone | Tumors | Cancer | Index Medicus | TGFβR1 inhibitor | dinutuximab | adoptive cell therapy | galunisertib | immunotherapy
Journal Article
Cancer Research, ISSN 0008-5472, 09/2017, Volume 77, Issue 18, pp. 5142 - 5157
Cancer-associated fibroblasts (CAF) have been suggested to originate from mesenchymal stromal cells (MSC), but their relationship with MSCs is not clear. Here,... 
SURVIVAL | STEM-CELLS | MICROENVIRONMENT | ONCOLOGY | ACTIVATION PROTEIN | STAT3 | TUMOR-ASSOCIATED MACROPHAGES | MYOFIBROBLASTS | NEUROBLASTOMA | DRUG-RESISTANCE | INTERLEUKIN-6 | Apoptosis - drug effects | Cancer-Associated Fibroblasts - metabolism | Humans | Cancer-Associated Fibroblasts - drug effects | Culture Media, Conditioned - pharmacology | Male | Janus Kinase 2 - metabolism | Biomarkers, Tumor - metabolism | Bone Marrow Cells - drug effects | Female | Pyrimidinones - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Neuroblastoma - pathology | STAT3 Transcription Factor - metabolism | Pyrazoles - pharmacology | Tumor Microenvironment - drug effects | Mesenchymal Stromal Cells - drug effects | Bone Marrow Cells - pathology | Mesenchymal Stromal Cells - metabolism | MAP Kinase Kinase 1 - metabolism | Mice, SCID | Xenograft Model Antitumor Assays | Cancer-Associated Fibroblasts - pathology | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Differentiation - drug effects | Neuroblastoma - drug therapy | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Neuroblastoma - metabolism | Mesenchymal Stromal Cells - pathology | Bone Marrow Cells - metabolism | Pyridones - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Cell survival | Mesenchyme | Immunodeficiency | Stat3 protein | Extracellular signal-regulated kinase | Etoposide | Bone tumors | Neuroblastoma | Macrophages | Survival | Neuroblastoma cells | Chemotherapy | Stromal cells | Janus kinase 2 | Xenografts | Bone marrow | Fibroblasts | Cancer | Tumors | Immune system
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2009, Volume 41, Issue 6, pp. 718 - 723
Journal Article
Journal of the American College of Surgeons, ISSN 1072-7515, 10/2019, Volume 229, Issue 4, pp. S217 - S217
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2008, Volume 358, Issue 24, pp. 2585 - 2593
Journal Article