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Journal Article
Psychopharmacology, ISSN 0033-3158, 4/2013, Volume 226, Issue 4, pp. 687 - 698
Glutamate and orexin/hypocretin systems are involved in Pavlovian cue-triggered drug seeking.Here, we asked whether orexin and glutamate interact within... 
Self-administration | Neurosciences | Relapse | AMPA | Glutamate | Hypocretin | Biomedicine | Addiction | Conditioned | NMDA | Cocaine | Pharmacology/Toxicology | Psychiatry | Ventral tegmental area | NUCLEUS-ACCUMBENS DOPAMINE | PSYCHIATRY | HYPOCRETIN-OREXIN | NEUROSCIENCES | DUAL-PROBE MICRODIALYSIS | PREFRONTAL CORTEX | INFRALIMBIC CORTEX | CONTEXTUAL FEAR MEMORY | RECEPTOR ANTAGONISM | PHARMACOLOGY & PHARMACY | CONDITIONED-STIMULUS | METHYL-D-ASPARTATE | Benzoxazoles - pharmacology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Receptors, G-Protein-Coupled - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Receptors, Neuropeptide - drug effects | Male | Receptors, Neuropeptide - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Dose-Response Relationship, Drug | Drug-Seeking Behavior | Self Administration | Urea - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, G-Protein-Coupled - drug effects | Cues | Orexins | Signal Transduction | Rats | Neuropeptides - metabolism | Orexin Receptors | Rats, Sprague-Dawley | 6-Cyano-7-nitroquinoxaline-2,3-dione - administration & dosage | Cocaine - administration & dosage | Animals | Ventral Tegmental Area - metabolism | 2-Amino-5-phosphonovalerate - administration & dosage | Glutamic Acid - metabolism | Urea - pharmacology | Receptors, AMPA - antagonists & inhibitors | Brain | Neurotransmitters | Animal behavior | Rodents | Addictive behaviors
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 08/2009, Volume 30, Issue 3, pp. 493 - 503
Journal Article
Psychopharmacology, ISSN 0033-3158, 3/2013, Volume 226, Issue 1, pp. 155 - 165
The orexin/hypocretin system has recently been implicated in reward-seeking, especially for highly salient food and drug rewards. We reasoned that this system... 
Obesity | Neurosciences | Biomedicine | Addiction | Palatable food | Conditioned stimuli | Pharmacology/Toxicology | Reward-based feeding | Psychiatry | Orexin | DIFFERENTIAL EXPRESSION | INDUCED REINSTATEMENT | PSYCHIATRY | HIGH-FAT DIET | FOOD-INTAKE | RECEPTOR MESSENGER-RNA | NEUROSCIENCES | ANTAGONIST SB-334867 | CORTICAL ACETYLCHOLINE-RELEASE | HYPOTHALAMIC OREXIN NEURONS | OPIOID STIMULATION | PHARMACOLOGY & PHARMACY | NUCLEUS-ACCUMBENS SHELL | Immunohistochemistry | Benzoxazoles - pharmacology | Extinction, Psychological - drug effects | Male | Intracellular Signaling Peptides and Proteins - metabolism | Self Administration | Conditioning, Operant - drug effects | Urea - analogs & derivatives | Behavior, Animal - drug effects | Food Deprivation | Neurons - metabolism | Neurons - drug effects | Sucrose - administration & dosage | Orexins | Receptors, Neuropeptide - antagonists & inhibitors | Rats | Neuropeptides - metabolism | Orexin Receptors | Rats, Sprague-Dawley | Drug-Seeking Behavior - drug effects | Reinforcement Schedule | Animals | Analysis of Variance | Receptors, G-Protein-Coupled - antagonists & inhibitors | Reward | Urea - pharmacology | Drugs | Sucrose | Animal behavior | Rodents | Self-administration | Extinction | Neurons | Hypothalamus (dorsomedial) | Immediate-early proteins | Fos protein | Motivation | Food availability | Reinstatement | Reinforcement | c-Fos protein | Food | reward-based feeding | orexin | palatable food | obesity | addiction | conditioned stimuli
Journal Article
Journal Article
Journal Article
Brain Research, ISSN 0006-8993, 2008, Volume 1224, pp. 43 - 52
Abstract Activation of noradrenergic locus coeruleus (LC) neurons promotes wakefulness and behavioral arousal. In rats, LC neurons receive circadian inputs via... 
Neurology | Dorsomedial | Sleep | Arousal | Norepinephrine | Hypothalamus | Circadian | Orexin | Hypocretin | Locus coeruleus | Waking | norepinephrine | NORADRENERGIC SYSTEM | SPINAL-CORD | dorsomedial | locus coeruleus | NEUROSCIENCES | sleep | circadian | CERULEUS NEURONS | SLEEP-WAKING CYCLE | MESSENGER-RNA | SUPRACHIASMATIC NUCLEUS | BEHAVIORAL STATE | hypocretin | waking | CIRCADIAN REGULATION | orexin | RAT-BRAIN | NEURAL CIRCUIT | hypothalamus | arousal | Intracellular Signaling Peptides and Proteins - pharmacology | Benzoxazoles - pharmacology | Synaptic Transmission - physiology | Receptors, G-Protein-Coupled - metabolism | Locus Coeruleus - drug effects | Male | Receptors, Neuropeptide - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Locus Coeruleus - cytology | Neuropeptides - pharmacology | Urea - analogs & derivatives | Axons - ultrastructure | Synaptic Transmission - drug effects | Microinjections | Orexins | Dorsomedial Hypothalamic Nucleus - cytology | Receptors, Neuropeptide - antagonists & inhibitors | Axons - metabolism | Rats | Neuropeptides - metabolism | Circadian Rhythm - physiology | Orexin Receptors | Dorsomedial Hypothalamic Nucleus - metabolism | Rats, Sprague-Dawley | Action Potentials - physiology | Animals | Neural Pathways - cytology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Neural Pathways - metabolism | Wakefulness - physiology | Urea - pharmacology | Locus Coeruleus - metabolism | Phosphates | Noradrenaline | Cholera toxin | dorsomedial hypothalamus
Journal Article
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 02/2020, Volume 134, p. 104616
The pontine nucleus locus coeruleus (LC) is the primary source of noradrenergic (NE) projections to the brain and is important for working memory, attention,... 
Locus Coeruleus | Memory | Neuroinflammation | Norepinephrine | Down syndrome | Designer receptors exclusively activated by designer drugs (DREADD) | Alzheimer's disease | NUCLEUS BASALIS | ALZHEIMERS-DISEASE | TS65DN MICE | COERULEUS NORADRENERGIC SYSTEM | G-PROTEIN | NEUROSCIENCES | BETA-1 ADRENERGIC-RECEPTOR | LOCUS-COERULEUS | SPATIAL MEMORY | DEFICITS | AGE
Journal Article
Journal Article