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Pharmacology and Therapeutics, ISSN 0163-7258, 01/2010, Volume 125, Issue 1, pp. 11 - 26
α5IA is a triazolophthalazine that selectively attenuates the effects of GABA at GABA receptors containing an α5 subunit. It enhances long-term potentiation in... 
GABA | α5IA | Cognition | Subtype-selective | Inverse agonist | benzodiazepine
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2019
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2011, Volume 11, Issue 9, pp. 1176 - 1202
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2011, Volume 11, Issue 9, pp. 1203 - 1214
Journal Article
Drug Discovery Today, ISSN 1359-6446, 09/2009, Volume 14, Issue 17-18, pp. 866 - 875
Journal Article
Drug Discovery Today, ISSN 1359-6446, 2009, Volume 14, Issue 17, pp. 866 - 875
Gamma-amino butyric acid (GABA) is the most abundant inhibitory neurotransmitter in the central nervous system (CNS) and many physiological actions are... 
DELTA-SUBUNIT | A RECEPTORS | ENHANCES COGNITION | ALPHA-5 SUBUNIT | NEUROACTIVE STEROIDS | INVERSE AGONIST | PHARMACOLOGY & PHARMACY | RAT-BRAIN | NEURONAL EXCITABILITY | TONIC INHIBITION | SUBUNIT-DEFICIENT MICE
Journal Article
CNS Neuroscience and Therapeutics, ISSN 1755-5930, 03/2008, Volume 14, Issue 1, pp. 25 - 35
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2010, Volume 125, Issue 1, pp. 11 - 26
α5IA is a triazolophthalazine that selectively attenuates the effects of GABA at GABA receptors containing an α5 subunit. It enhances long-term potentiation in... 
α5IA | Subtype-selective | Inverse agonist | Cognition | GABA A benzodiazepine
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 01/2010, Volume 125, Issue 1, p. 11
[alpha]5IA is a triazolophthalazine that selectively attenuates the effects of GABA at GABA.sub.A receptors containing an [alpha]5 subunit. It enhances... 
Neurosciences | GABA | Benzodiazepines
Journal Article
Pharmacology & Therapeutics, ISSN 0163-7258, 01/2010, Volume 125, Issue 1, pp. 11 - 26
a5IA is a triazolophthalazine that selectively attenuates the effects of GABA at GABA sub(A) receptors containing an a5 subunit. It enhances long-term... 
Journal Article
Current Topics in Behavioral Neurosciences, ISSN 1866-3370, 2010, Volume 2, pp. 331 - 360
Conference Proceeding
Neuropharmacology, ISSN 0028-3908, 11/2006, Volume 51, Issue 6, pp. 1023 - 1029
The in vitro and in vivo properties of L-655,708, a compound with higher affinity for GABA receptors containing an α5 compared to an α1, α2 or α3 subunit have... 
receptor | Morris water maze | Proconvulsant | Inverse agonist | Benzodiazepine | GABA | Cognition | α5 Subunit | L-655,708
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2010, Volume 332, Issue 1, pp. 4 - 16
Journal Article
Psychopharmacology, ISSN 0033-3158, 05/2011, Volume 215, Issue 2, p. 311
  Experimental evidence suggests that the differential behavioral effects of benzodiazepines depend on their relative actions at γ-aminobutyric acid type A... 
Psychotropic drugs | Psychopharmacology | Monkeys & apes
Journal Article
Drug Discovery Today, ISSN 1359-6446, 09/2009, Volume 14, Issue 17-18, p. 866
Gamma-amino butyric acid (GABA) is the most abundant inhibitory neurotransmitter in the central nervous system (CNS) and many physiological actions are... 
Physiological aspects | GABA | Saturated fatty acids | Benzodiazepines
Journal Article
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