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Microscopy and Microanalysis, ISSN 1431-9276, 07/2017, Volume 23, Issue S1, pp. 1312 - 1313
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7409, pp. 96 - 99
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, p. 96
  The prevalence of dementia in the Western world in people over the age of 60 has been estimated to be greater than 5%, about two-thirds of which are due to... 
Nursing | Cognition & reasoning | Older people | Cognitive ability | Genetics | Genomes | Mutation | Alzheimers disease
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 11/2014, Volume 6, Issue 261, pp. 261ra154 - 261ra154
Journal Article
Scientific Reports (Nature Publisher Group), 12/2016, Volume 6, p. 39374
Accumulation of amyloid-β (Aβ) peptides and amyloid plaque deposition in brain is postulated as a cause of Alzheimer's disease (AD). The precise pathological... 
Neurotoxicity | Neurodegenerative diseases | Immunoglobulin G | Fibrils | β-Amyloid | Disaggregation | Affinity | Hydrophobicity | Alzheimers disease | Alzheimer's disease | Conformation | Crystal structure
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2012, Volume 32, Issue 28, pp. 9677 - 9689
Passive immunization against beta-amyloid (A beta) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD).... 
APP TRANSGENIC MICE | NATURAL OLIGOMERS | HUMAN IGG1 | ALZHEIMERS-DISEASE | PROTEIN-KINASE | LONG-TERM POTENTIATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | PASSIVE-IMMUNIZATION | SECRETED OLIGOMERS | P38 MAP KINASE | Microglia - metabolism | Humans | Middle Aged | Male | Green Fluorescent Proteins - genetics | Neuroprotective Agents - metabolism | Alzheimer Disease - pathology | Neuroprotective Agents - pharmacology | Time Factors | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Statistics, Nonparametric | Aged, 80 and over | Neurons - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Alzheimer Disease - immunology | Receptors, Chemokine - genetics | Plaque, Amyloid - immunology | Disease Models, Animal | Animals, Newborn | Rats | Mice, Transgenic | Mutation - genetics | Rats, Sprague-Dawley | Microscopy, Confocal | Plaque, Amyloid - metabolism | Mice | CX3C Chemokine Receptor 1 | Alzheimer Disease - blood | Immunoglobulin G - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dose-Response Relationship, Immunologic | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Immunoglobulin G - pharmacology | Female | Neurons - drug effects | Peptide Fragments - metabolism | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Plaque, Amyloid - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Alzheimer Disease - therapy | Cells, Cultured | Presenilin-1 - genetics | Hippocampus - cytology | Gene Expression Regulation - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Amyloid beta-Peptides - immunology | Aged | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2014, Volume 20, Issue 12, pp. 1452 - 1457
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2011, Volume 3, Issue 84, pp. 84ra43 - 84ra43
Journal Article
Neuron, ISSN 0896-6273, 08/2000, Volume 27, Issue 2, pp. 265 - 277
To determine how signals emanating from Trk transmit neurotrophin actions in primary neurons, we tested the ability of TrkB mutated at defined effector binding... 
PHOSPHOLIPASE C-GAMMA-1 | NEUROTROPHIC FACTORS | RETROGRADE SIGNAL | NEURITE OUTGROWTH | PROTEIN-KINASE | PHOSPHATIDYLINOSITOL 3-KINASE | PATHWAYS INVOLVING SHC | RAT SYMPATHETIC NEURONS | MAP KINASE KINASE | TRANSCRIPTION FACTOR | NEUROSCIENCES | Proteins | Neurons | Growth
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, pp. 39374 - 39374
Accumulation of amyloid-beta (A beta) peptides and amyloid plaque deposition in brain is postulated as a cause of Alzheimer's disease (AD). The precise... 
PROTEIN | FIBRILS | ATOMIC-RESOLUTION STRUCTURE | ALZHEIMERS-DISEASE | AMYLOID-BETA | MULTIDISCIPLINARY SCIENCES | X-RAY-DIFFRACTION | ANTIBODY | CONFORMATION | OLIGOMERS | PEPTIDE
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 9, pp. 3900 - 3908
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2017, Volume 174, Issue 22, pp. 4173 - 4185
Journal Article