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Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1334 - 1340
Juvenile myelomonocytic leukemia (JMML) is a rare and severe myelodysplastic and myeloproliferative neoplasm of early childhood initiated by germline or... 
LYSINE 27 | COMPLEX | MULTIPLE MECHANISMS | NRAS MUTATION | GENETICS & HEREDITY | MYELOID MALIGNANCIES | RHO-GTPASES | DETECTABLE CLONAL MOSAICISM | CANCER | NERVE SHEATH TUMORS | SOMATIC MUTATIONS | ras Proteins - genetics | Leukemia, Myelomonocytic, Juvenile - metabolism | Polycomb Repressive Complex 2 - genetics | Humans | Leukemia, Myeloid - genetics | Transcriptome | Child, Preschool | ras Proteins - metabolism | Infant | Male | Phosphatidylinositol 3-Kinases - metabolism | Protein Subunits - metabolism | DNA Copy Number Variations | Female | Acetylation | Leukemia, Myelomonocytic, Juvenile - genetics | Child | Protein Subunits - genetics | Acute Disease | Gene Regulatory Networks - genetics | Signal Transduction - genetics | Disease Progression | Phosphatidylinositol 3-Kinases - genetics | Microscopy, Confocal | Leukemia, Myeloid - metabolism | Survival Analysis | Histones - metabolism | Mutation | Methylation | Polycomb Repressive Complex 2 - metabolism | Sequence Analysis, DNA - methods | Gene mutations | Leukemia in children | Development and progression | Genetic aspects | Identification and classification | Health aspects | Myeloproliferative disorders | Laboratories | Colonies & territories | Genomes | Kinases | Patients | Data bases | Proteins | Studies | Archives & records | Acquisitions & mergers | Tumors | Cancer | Life Sciences | Genetics
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 10/2014, Volume 51, Issue 10, pp. 689 - 697
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 937 - 937
Abstract L-asparaginase (L-ASP) is an important drug in the treatment of acute lymphoblastic leukemia (ALL) demonstrating efficacy in a broad range of... 
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 02/2015, Volume 168, Issue 4, pp. 518 - 525
Summary Cataract was prospectively assessed by serial slip lamp tests in 271 patients included in the Leucémie Enfants Adolescents (LEA) programme, the French... 
leukaemia | cataract | haematopoietic stem cell transplantation | irradiation | late effects | Irradiation | Late effects | Cataract | Haematopoietic stem cell transplantation | Leukaemia | TOTAL-BODY IRRADIATION | BONE-MARROW-TRANSPLANTATION | CHEMOTHERAPY | CHILDREN | SF-36 | ACUTE LYMPHOBLASTIC-LEUKEMIA | COMPLICATIONS | HEMATOLOGY | SURVIVORS | HEALTH SURVEY | REMISSION | Myeloablative Agonists - therapeutic use | Cataract - chemically induced | Follow-Up Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Cataract - epidemiology | Radiotherapy - adverse effects | Incidence | Dose-Response Relationship, Drug | Young Adult | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Adult | Dose Fractionation | Female | Transplantation Conditioning - adverse effects | Graft vs Host Disease - etiology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications | Busulfan - therapeutic use | Cataract - etiology | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Hematopoietic Stem Cell Transplantation | Combined Modality Therapy | Adolescent | Quality of Life | Immunosuppressive Agents - adverse effects | Medical research | Stem cells | Medicine, Experimental | Transplantation | Risk factors | Hematopoietic stem cells | Life Sciences | Hematology | Human health and pathology
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 06/2016, Volume 81, Issue 6, pp. 1195 - 1196
We describe herein the first reported case of a drug–drug interaction between dasatinib and esomeprazole in a patient with Philadelphia-positive acute... 
OMEPRAZOLE | PROTON PUMP INHIBITORS | PHARMACOLOGY & PHARMACY | PHARMACOKINETICS | Life Sciences | Case Report
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2013, Volume 19, Issue 7, pp. 1065 - 1072
Journal Article