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1. Full Text Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease
by Feagan, Brian G and Sandborn, William J and Gasink, Christopher and Jacobstein, Douglas and Lang, Yinghua and Friedman, Joshua R and Blank, Marion A and Johanns, Jewel and Gao, Long-Long and Miao, Ye and Adedokun, Omoniyi J and Sands, Bruce E and Hanauer, Stephen B and Vermeire, Severine and Targan, Stephan and Ghosh, Subrata and de Villiers, Willem J and Colombel, Jean-Frédéric and Tulassay, Zsolt and Seidler, Ursula and Salzberg, Bruce A and Desreumaux, Pierre and Lee, Scott D and Loftus, Edward V and Dieleman, Levinus A and Katz, Seymour and Rutgeerts, Paul and UNITI-IM-UNITI Study Grp and UNITI–IM-UNITI Study Group
The New England journal of medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 20, pp. 1946 - 1960
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Humans | Middle Aged | Induction Chemotherapy | Male | Remission Induction | Ustekinumab - therapeutic use | Ustekinumab - adverse effects | Ustekinumab - pharmacokinetics | Crohn Disease - drug therapy | Ustekinumab - immunology | Adult | Female | Maintenance Chemotherapy | Infusions, Intravenous | Intravenous administration | Cytokines | Body weight | Clinical trials | Interleukin 23 | Interleukin 12 | Antagonists | Patients | Crohns disease | Side effects | Tumor necrosis factor | Immunotherapy | Monoclonal antibodies | Tumor necrosis factor-TNF | Remission | Index Medicus | Abridged Index Medicus
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2. Full Text Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
by Jostins, Luke and Ripke, Stephan and Weersma, Rinse K and Duerr, Richard H and McGovern, Dermot P and Hui, Ken Y and Lee, James C and Schumm, L. Philip and Sharma, Yashoda and Anderson, Carl A and Essers, Jonah and Mitrovic, Mitja and Ning, Kaida and Cleynen, Isabelle and Theatre, Emilie and Spain, Sarah L and Raychaudhuri, Soumya and Goyette, Philippe and Wei, Zhi and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Amininejad, Leila and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anews, Jane M and Baidoo, Leonard and Balschun, Tobias and Bampton, Peter A and Bitton, Alain and Boucher, Gabrielle and Brand, Stephan and Büning, Carsten and Cohain, Ariella and Cichon, Sven and D'Amato, Mauro and de Jong, Dirk and Devaney, Kathy L and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Ferguson, Lynnette R and Franchimont, Denis and Fransen, Karin and Gearry, Richard and Georges, Michel and Gieger, Christian and Glas, Jürgen and Haritunians, Talin and Ponsioen, Cyriel Y and van Limbergen, Johan E and Int IBD Genetics Consortium IIBDGC and International IBD Genetics Consortium (IIBDGC) and The International IBD Genetics Consortium (IIBDGC)
Nature (London), ISSN 0028-0836, 2012, Volume 491, Issue 7422, pp. 119 - 124
no | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Dermatology | Psoriasis. Parapsoriasis. Lichen | Diseases of the osteoarticular system | Inflammatory joint diseases | Biological and medical sciences | Medical sciences | Other diseases. Semiology | Crohn Disease - genetics | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Mycobacterium tuberculosis - immunology | Inflammatory Bowel Diseases - physiopathology | Colitis, Ulcerative - immunology | Host-Pathogen Interactions - immunology | Mycobacterium tuberculosis - pathogenicity | Haplotypes - genetics | Mycobacterium - pathogenicity | Mycobacterium Infections - genetics | Inflammatory Bowel Diseases - genetics | Crohn Disease - microbiology | Mycobacterium Infections - microbiology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Reproducibility of Results | Mycobacterium - immunology | Crohn Disease - immunology | Genome, Human - genetics | Phenotype | Colitis, Ulcerative - microbiology | Host-Pathogen Interactions - genetics | Polymorphism, Single Nucleotide - genetics | Inflammatory Bowel Diseases - microbiology | Crohn Disease - physiopathology | Colitis, Ulcerative - physiopathology | Inflammatory bowel disease | Candidates | Tuberculosis | Architecture | Genetics | Genomes | Diabetes | Gene expression | Health risk assessment | Immune system | Index Medicus | Medicin och hälsovetenskap
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3. Full Text IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
by Momozawa, Yukihide and Dmitrieva, Julia and Théâtre, Emilie and Deffontaine, Valérie and Rahmouni, Souad and Charloteaux, Benoît and Crins, François and Docampo, Elisa and Elansary, Mahmoud and Gori, Ann-Stephan and Lecut, Christelle and Mariman, Rob and Mni, Myriam and Oury, C. cile and Altukhov, Ilya and Alexeev, Dmitry and Aulchenko, Yuri and Amininejad, Leila and Bouma, Gerd and Hoentjen, Frank and Löwenberg, Mark and Oldenburg, Bas and Pierik, Marieke J and Vander Meulen-de Jong, Anea E and van der Woude, C. Janneke and Visschedijk, Marijn C and Lathrop, Mark and Hugot, Jean-Pierre and Weersma, Rinse K and de Vos, Martine and Franchimont, Denis and Vermeire, Severine and Kubo, Michiaki and Louis, Edouard and Georges, Michel and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anderson, Carl A and Anews, Jane M and Annese, Vito and Aumais, Guy and Baidoo, Leonard and Baldassano, Robert N and Bampton, Peter A and Barclay, Murray and Ponsioen, Cyriel Y and van Limbergen, Johan E and Int IBD Genetics Consortium and International IBD Genetics Consortium and The International IBD Genetics Consortium
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 2427 - 18
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Crohn Disease - genetics | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Middle Aged | Genotype | Male | Gene Expression Profiling | Multifactorial Inheritance | Sequence Analysis, DNA | Inflammatory Bowel Diseases - genetics | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Cohort Studies | Inflammatory bowel disease | Inflammatory bowel diseases | Intestine | Modules | Genes | Health risks | Risk | Gene expression | Loci | Disease control | Index Medicus | Medicin och hälsovetenskap
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4. Full Text The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease
by Fedorak, Richard N and Feagan, Brian G and Hotte, Naomi and Leddin, Des and Dieleman, Levinus A and Petrunia, Denis M and Enns, Robert and Bitton, Alain and Chiba, Naoki and Paré, Pierre and Rostom, Alaa and Marshall, John and Depew, William and Bernstein, Charles N and Panaccione, Remo and Aumais, Guy and Steinhart, A. Hillary and Cockeram, Alan and Bailey, Robert J and Gionchetti, Paolo and Wong, Cindy and Madsen, Karen
Clinical gastroenterology and hepatology, ISSN 1542-3565, 2015, Volume 13, Issue 5, pp. 928 - 935.e2
Gastroenterology and Hepatology | Microbiota | Streptococcus | Treatment | Inflammatory Bowel Disease | IBDQ | Bifidobacteria | Inflammatory bowel disease | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Probiotics - administration & dosage | Recurrence | Ileum - pathology | Double-Blind Method | Cytokines - analysis | Humans | Middle Aged | Crohn Disease - surgery | Male | Treatment Outcome | Crohn Disease - prevention & control | Biopsy | Colonoscopy | Immunoglobulin Light Chains, Surrogate | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Placebos - administration & dosage | Anti-inflammatory drugs | Surgical clinics | Bacteria | Index Medicus
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5. Full Text A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
by Bodea, Corneliu A and Neale, Benjamin M and Ripke, Stephan and Barclay, Murray and Peyrin-Biroulet, Laurent and Chamaillard, Mathias and Colombel, Jean-Frederick and Cottone, Mario and Croft, Anthony and D’Incà, Renata and Halfvarson, Jonas and Hanigan, Katherine and Henderson, Paul and Hugot, Jean-Pierre and Karban, Amir and Kennedy, Nicholas A and Khan, Mohammed Azam and Lémann, Marc and Levine, Arie and Massey, Dunecan and Milla, Monica and Montgomery, Grant W and Ng, Sok Meng Evelyn and Oikonomou, Ioannis and Peeters, Harald and Proctor, Deborah D and Rahier, Jean-Francois and Roberts, Rebecca and Rutgeerts, Paul and Seibold, Frank and Stronati, Laura and Taylor, Kirstin M and Törkvist, Leif and Ublick, Kullak and Van Limbergen, Johan and Van Gossum, Andre and Vatn, Morten H and Zhang, Hu and Zhang, Wei and Andrews, Jane M and Bampton, Peter A and Florin, Timothy H and Gearry, Richard and Krishnaprasad, Krupa and Lawrance, Ian C and Mahy, Gillian and Radford-Smith, Graham and Roberts, Rebecca L and Simms, Lisa A and Amininijad, Leila and Cleynen, Isabelle and Dewit, Olivier and Franchimont, Denis and Georges, Michel and Laukens, Debby and Theatre, Emilie and Van Gossum, André and Vermeire, Severine and Aumais, Guy and Baidoo, Leonard and Barrie, Arthur M and Beck, Karen and Bernard, Edmond-Jean and Binion, David G and Bitton, Alain and Brant, Steve R and Cho, Judy H and Cohen, Albert and Croitoru, Kenneth and Daly, Mark J and Datta, Lisa W and Deslandres, Colette and Duerr, Richard H and Dutridge, Debra and Ferguson, John and Fultz, Joann and Goyette, Philippe and Greenberg, Gordon R and Haritunians, Talin and Jobin, Gilles and Katz, Seymour and Lahaie, Raymond G and McGovern, Dermot P and Nelson, Linda and Ng, Sok Meng and Ning, Kaida and Paré, Pierre and Regueiro, Miguel D and Rioux, John D and Ruggiero, Elizabeth and Schumm, L. Philip and Schwartz, Marc and Scott, Regan and Sharma, Yashoda and Silverberg, Mark S and Spears, Denise and Steinhart, A. Hillary and Stempak, Joanne M and Swoger, Jason M and Tsagarelis, Constantina and ... and The International IBD Genetics Consortium and Int IBD Genetics Consortium and International IBD Genetics Consortium
American journal of human genetics, ISSN 0002-9297, 05/2016, Volume 98, Issue 5, pp. 857 - 868
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetics, Population | Genetic Predisposition to Disease | Disease - genetics | Gene Frequency | Humans | Bayes Theorem | Heredity - genetics | Polymorphism, Single Nucleotide - genetics | Genotype | Software | Case-Control Studies | Genetic Linkage | Genetic research | Usage | Methods | Gaussian processes | Genetics | Disease | Genes | Risk factors | Index Medicus
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6. Full Text IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
by Momozawa, Y and Dmitrieva, J and Théâtre, E and Deffontaine, V and Rahmouni, S and Charloteaux, B and Crins, F and Docampo, E and Elansary, M and Gori, A.-S and Lecut, C and Mariman, R and Mni, M and Oury, C and Altukhov, I and Alexeev, D and Aulchenko, Yurii and Amininejad, L and Bouma, Gerd and Hoentjen, F and Löwenberg, M and Oldenburg, Bas and Pierik, Marieke and Vander Meulen-De Jong, A.E and Woude, Janneke and Visschedijk, Marijn and Lathrop, Mark and Hugot, J and Weersma, Rinse and De Vos, M and Franchimont, Denis and Vermeire, Séverine and Kubo, M and Louis, Edouard and Georges, M and Abraham, C and Achkar, J.-P and Ahmad, Tariq and Ananthakrishnan, A.N and Andersen, V and Anderson, C.A and Anews, J.M and Annese, Vito and Aumais, G and Baidoo, L and Baldassano, Robert and Bampton, P.A and Barclay, M and Barrett, Jeffrey and Bayless, T.M and Bethge, J and Bitton, A and Boucher, Gabrielle and Brand, S and Brandt, B and Brant, S.R and Büning, Carsten and Chew, A and Cho, J.H and Cleynen, Isabelle and Cohain, A and Croft, A and Daly, M.J and D'Amato, M and Danese, Silvio and De Jong, Dirk J and Denapiene, G and Denson, L.A and Devaney, K.L and Dewit, O and D'Inca, Renata and Dubinsky, Marla and Duerr, Richard and Edwards, Cathryn and Ellinghaus, David and Essers, Jonah and Ferguson, L.R and Festen, Eleonora and Fleshner, P and Florin, T and Franke, A and Fransen, K and Gearry, R and Gieger, Christian and Glas, Jürgen and Goyette, Philippe and Green, Todd and Griffiths, Anne and Guthery, S.L and Hakonarson, Hakon and Halfvarson, J and Hanigan, K and Haritunians, Talin and Hart, Ailsa and Hawkey, S and Hayward, N.K and Hedl, M and Henderson, P and Hu, X and Huang, Hailiang and ...
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1
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7. Full Text A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition
by Li, Dalin and Achkar, Jean-Paul and Haritunians, Talin and Jacobs, Jonathan P and Hui, Ken Y and D'Amato, Mauro and Brand, Stephan and Radford-Smith, Graham and Halfvarson, Jonas and Niess, Jan-Hendrik and Kugathasan, Subra and Büning, Carsten and Schumm, L. Philip and Klei, Lambertus and Ananthakrishnan, Ashwin and Aumais, Guy and Baidoo, Leonard and Dubinsky, Marla and Fiocchi, Claudio and Glas, Jürgen and Milgrom, Raquel and Proctor, Deborah D and Regueiro, Miguel and Simms, Lisa A and Stempak, Joanne M and Targan, Stephan R and Törkvist, Leif and Sharma, Yashoda and Devlin, Bernie and Borneman, James and Hakonarson, Hakon and Xavier, Ramnik J and Daly, Mark and Brant, Steven R and Rioux, John D and Silverberg, Mark S and Cho, Judy H and Braun, Jonathan and McGovern, Dermot P.B and Duerr, Richard H
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2016, Volume 151, Issue 4, pp. 724 - 732
Gastroenterology and Hepatology | Inflammatory Bowel Diseases | Genetics | Microbiota | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Crohn Disease - genetics | Humans | Risk Factors | Colitis, Ulcerative - genetics | Genotype | Male | Genetic Pleiotropy | Mutation, Missense | Gastrointestinal Microbiome - genetics | Case-Control Studies | Colitis, Ulcerative - microbiology | Alleles | Cation Transport Proteins - genetics | Crohn Disease - microbiology | Female | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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