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Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2016, Volume 59, Issue 7, pp. 3392 - 3408
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase responsible for the development of different tumor types. Despite the remarkable clinical... 
CELL LUNG-CANCER | EML4-ALK | CHEMISTRY, MEDICINAL | FUSION | GENE | RESISTANCE | NEUROBLASTOMA | GENERATION | IDENTIFICATION | REARRANGEMENTS | ACTIVATING MUTATIONS | Lung Neoplasms - drug therapy | Rats, Wistar | Humans | Lung Neoplasms - metabolism | Receptor, trkA - antagonists & inhibitors | Crystallography, X-Ray | Lung Neoplasms - pathology | Antineoplastic Agents - administration & dosage | Indazoles - administration & dosage | Benzamides - administration & dosage | Protein Kinase Inhibitors - chemistry | Anaplastic Lymphoma Kinase | Microsomes, Liver - drug effects | Receptor, trkB - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Tumor Cells, Cultured | Benzamides - chemistry | Proto-Oncogene Proteins - antagonists & inhibitors | Indazoles - chemistry | Administration, Oral | Crystallization | Receptor, trkC - antagonists & inhibitors | Rats | Antineoplastic Agents - chemistry | Mice, SCID | Blood-Brain Barrier - drug effects | Drug Discovery | Blotting, Western | Indazoles - pharmacology | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Animals | Mice, Nude | Cell Membrane Permeability - drug effects | Dogs | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Geospatial Health, ISSN 1827-1987, 05/2018, Volume 13, Issue 1, pp. 188 - 194
Viral hepatitis is a major public health problem in Brazil and worldwide. We retrospectively analyzed 338 cases of hepatitis A, B and C in Maringa, Parana... 
Co-infection | Demography | Brazil | Health education | Epidemiology | Health surveys | Human viral hepatitis | VIRUS | VACCINE | MARKERS | SEROPREVALENCE | IMMUNOGENICITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CITY | HEALTH CARE SCIENCES & SERVICES
Journal Article
Biomarkers in Medicine, ISSN 1752-0363, 01/2018, Volume 12, Issue 1, pp. 27 - 34
Aim: Plasma Gas6 was tested as an alternative to Baveno VI criteria (liver stiffness <20 kPa and platelet count >150 x 10(9)/l) in an endoscopy-sparing... 
Gas6 | cirrhosis | esophageal varices | TRANSIENT ELASTOGRAPHY | FIBROSIS | MEDICINE, RESEARCH & EXPERIMENTAL | VALIDATION | RISK | PROTEIN-S | PORTAL-HYPERTENSION
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7598, pp. 245 - 249
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 05/2010, Volume 87, Issue 5, pp. 869 - 875
Journal Article
Cell Reports, ISSN 2211-1247, 12/2015, Volume 13, Issue 9, pp. 1909 - 1921
Dectin-1 is a C-type lectin receptor critical in anti-fungal immunity, but Dectin-1 has not been linked to regulation of sterile inflammation or oncogenesis.... 
hepatocellular cancer | liver fibrosis | C-type lectin receptors | Liver fibrosis | Hepatocellular cancer | HEPATOCELLULAR-CARCINOMA | DENDRITIC CELLS | LIVER-REGENERATION | PANCREATIC CARCINOGENESIS | TOLL-LIKE RECEPTORS | STELLATE CELLS | DELTA-T-CELLS | LECTIN RECEPTORS | NEGATIVE REGULATOR | INNATE IMMUNITY | CELL BIOLOGY | Diethylnitrosamine - toxicity | Liver - pathology | Sepsis - etiology | Humans | Liver Neoplasms - chemically induced | Hepatocytes - metabolism | Recombinant Proteins - biosynthesis | Lectins, C-Type - genetics | Liver Cirrhosis - chemically induced | Lipopolysaccharide Receptors - metabolism | Recombinant Proteins - isolation & purification | Lectins, C-Type - metabolism | Hepatocytes - cytology | Liver Cirrhosis - metabolism | Macrophage Colony-Stimulating Factor - pharmacology | Liver Neoplasms - pathology | Lectins, C-Type - deficiency | Toll-Like Receptor 4 - antagonists & inhibitors | Macrophage Colony-Stimulating Factor - genetics | Lipopolysaccharides - toxicity | Cytokines - metabolism | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Inflammation | Macrophage Colony-Stimulating Factor - metabolism | Recombinant Proteins - pharmacology | Chemokine CCL2 - blood | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Up-Regulation - drug effects | Animals | Thioacetamide - toxicity | Signal Transduction - drug effects | Liver Neoplasms - metabolism | Liver Cirrhosis - pathology | Mice | Cell Transformation, Neoplastic - drug effects
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 352 - 11
Journal Article
by Bellelli, Giuseppe and Morandi, Alessandro and Di Santo, Simona G and Mazzone, Andrea and Cherubini, Antonio and Mossello, Enrico and Bo, Mario and Bianchetti, Angelo and Rozzini, Renzo and Zanetti, Ermellina and Musicco, Massimo and Ferrari, Alberto and Ferrara, Nicola and Trabucchi, Marco and Boffelli, Stefano and Stefano, Fabio Di and Filippi, Francesco De and Guerini, Fabio and Bertoletti, Erik and March, Albert and Margiotta, Alessandro and Mecocci, Patrizia and Addesi, Desireè and Fantò, Fausto and Dijik, Babette and Porrino, Paola and Cotroneo, Antonino Maria and Galli, Giovanni and Bruni, Amalia Cecilia and Bernardini, Bruno and Corsini, Carla and Cagnin, Annachiara and Zurlo, Amedeo and Barbagallo, Giuseppe and Lunardelli, Maria Lia and Martini, Emilio and Battaglia, Giuseppe and Latella, Raffaele and Petritola, Donatella and Sinforiani, Elena and Cester, Alberto and Formilan, Marino and Carbone, Pasqualina and Appollonio, Ildebrando and Cereda, Diletta and Tremolizzo, Lucio and Bottacchi, Edo and Lucchetti, Lucio and Mariani, Claudio and Rapazzini, Piero and Romanelli, Giuseppe and Marengoni, Alessandra and Zuliani, Giovanni and Bianchi, Lara and Suardi, Teresa and Muti, Ettore and Bottura, Renato and Sgrò, Giovanni and Mandas, Antonella and Serchisu, Luca and Crippa, Patrizia and Ivaldi, Claudio and Ungar, Andrea and Villani, Daniele and Raimondi, Clara and Mussi, Chiara and Isaia, Giancarlo and Provenzano, Giuseppe and Mari, Daniela and Odetti, Patrizio and Monacelli, Fiammetta and Incalzi, Raffaele Antonelli and Pluderi, Alice and Bellamoli, Claudio and Terranova, Luciano and Scarpini, Elio and D'Amico, Ferdinando and Cavallini, Maria Chiara and Guerrini, Gianbattista and Scotuzzi, Anna Maria and Chiarello, Antonino and Pilotto, Alberto and Tognini, Sara and Dell'Aquila, Giuseppina and Toigo, Gabriele and Ceschia, Giuliano and Piccinini, Maristella and Fabbo, Andrea and Zoli, Marco and Forti, Paola and Wenter, Christian and Basile, Giorgio and Lasagni, Anna and Padovani, Alessandro and Rozzini, Luca and Cottino, Maria and Vitali, Silvia and Tripi, Gabriele and Avanzi, Stefano and Annoni, Giorgio and ... and Italian Study Grp Delirium ISGoD and Italian Study Group on Delirium (ISGoD) and on behalf of the Italian Study Group on Delirium (ISGoD)
BMC Medicine, ISSN 1741-7015, 07/2016, Volume 14, Issue 1, p. 106
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 2289 - 2289
Abstract Abstract 2289 Introduction: One of the goals of stem cell medicine is the production of platelets from stem cells for transfusion therapy. The process... 
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 5, pp. 1844 - 1853
Journal Article