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science & technology (75) 75
life sciences & biomedicine (66) 66
humans (64) 64
pharmacology & pharmacy (53) 53
chemistry, medicinal (47) 47
molecular structure (43) 43
cell line, tumor (38) 38
biological and medical sciences (35) 35
drug screening assays, antitumor (35) 35
medical sciences (35) 35
pharmacology. drug treatments (34) 34
animals (33) 33
general pharmacology (32) 32
pharmacognosy. homeopathy. health food (32) 32
antineoplastic agents, phytogenic - pharmacology (31) 31
antineoplastic agents, phytogenic - isolation & purification (30) 30
pancreatic cancer (28) 28
chemistry (27) 27
antineoplastic agents, phytogenic - chemistry (26) 26
physical sciences (23) 23
mice (22) 22
plants, medicinal - chemistry (22) 22
pancreatic neoplasms - drug therapy (21) 21
panc-1 (20) 20
diterpenes - chemistry (19) 19
cytotoxicity (18) 18
diterpenes - isolation & purification (18) 18
myanmar (17) 17
plant extracts - chemistry (17) 17
diterpenes - pharmacology (15) 15
magnetic resonance spectroscopy (14) 14
plant extracts - pharmacology (14) 14
plant sciences (14) 14
structure-activity relationship (14) 14
dose-response relationship, drug (13) 13
food science & technology (13) 13
preferential cytotoxicity (13) 13
analysis (12) 12
drug discovery (12) 12
integrative & complementary medicine (12) 12
nuclear magnetic resonance, biomolecular (12) 12
seeds - chemistry (12) 12
apoptosis (11) 11
inhibitory concentration 50 (11) 11
pancreatic neoplasms - pathology (11) 11
propolis - chemistry (11) 11
structure (11) 11
antineoplastic agents - pharmacology (10) 10
caesalpinia - chemistry (10) 10
cancer (10) 10
antineoplastic agents - chemistry (9) 9
cell death (9) 9
cell proliferation - drug effects (9) 9
cell survival - drug effects (9) 9
female (9) 9
indonesia (9) 9
propolis (9) 9
research (9) 9
apoptosis - drug effects (8) 8
chemistry, multidisciplinary (8) 8
hela cells (8) 8
nitric oxide - antagonists & inhibitors (8) 8
proteins (8) 8
stereoisomerism (8) 8
terpenes (8) 8
toxicity (8) 8
antineoplastic agents (7) 7
care and treatment (7) 7
chemistry, organic (7) 7
macrophages - drug effects (7) 7
medicine (7) 7
oncology (7) 7
plant extracts - isolation & purification (7) 7
tumor cells, cultured (7) 7
anticarcinogenic activity, anticancer activity (6) 6
antineoplastic agents - isolation & purification (6) 6
biochemistry & molecular biology (6) 6
coumarins - pharmacology (6) 6
diterpenes (6) 6
flavonoids (6) 6
flavonoids - chemistry (6) 6
flavonoids - pharmacology (6) 6
lignans - isolation & purification (6) 6
lignans - pharmacology (6) 6
orthosiphon stamineus (6) 6
other bioactive products (6) 6
plant roots - chemistry (6) 6
rodents (6) 6
triterpenes - isolation & purification (6) 6
vietnam (6) 6
alkaloids (5) 5
antiausterity agent (5) 5
antiausterity agents (5) 5
antimalarials - pharmacology (5) 5
caesalpinia crista (5) 5
cell division - drug effects (5) 5
cell line (5) 5
chemistry, applied (5) 5
flavonoids - isolation & purification (5) 5
hygiene (5) 5
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1. Full Text Chrysin Inhibits Lymphangiogenesis in Vitro
by Prangsaengtong, Orawin and Athikomkulchai, Sirivan and Xu, Jiuxiang and Koizumi, Keiichi and Inujima, Akiko and Shibahara, Naotoshi and Shimada, Yutaka and Tadtong, Sarin and Awale, Suresh and Graduate School of Medicine and Pharmaceutical Sciences and Srinakharinwirot University and cDepartment of Japanese-Oriental (Kampo Medicine and eDepartment of Translational Research and bDepartment of Pharmacognosy and University of Toyama and Faculty of Pharmacy and dDepartment of Kampo Diagnostics and Institute of Natural Medicine and aDepartment of Biopharmacy
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 4, pp. 466 - 472
lymphangiogenesis | chrysin | in vitro | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Line | Endothelial Cells - metabolism | Propolis | Rats | Cell Adhesion - drug effects | RNA, Messenger - metabolism | Bees | Vascular Endothelial Growth Factor C - genetics | Lymphangiogenesis - drug effects | Cell Movement - drug effects | Animals | Cell Proliferation - drug effects | Flavonoids - pharmacology | Nitric Oxide - metabolism | Endothelial Cells - drug effects | Index Medicus
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2. Full Text Ancistrolikokines E-H and related 5,8′-coupled naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus likoko with antiausterity activities against PANC-1 human pancreatic cancer cells
by Fayez, Shaimaa and Feineis, Doris and Mudogo, Virima and Awale, Suresh and Bringmann, Gerhard
RSC advances, ISSN 2046-2069, 2017, Volume 7, Issue 85, pp. 53740 - 53751
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Coupling (molecular) | Alkaloids | Nuclear magnetic resonance--NMR | Toxicity | Dehydrogenation | Dichroism | Two dimensional analysis
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3. Full Text Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese: Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells
by Lombe, Blaise Kimbadi and Feineis, Doris and Mudogo, Virima and Brun, Reto and Awale, Suresh and Bringmann, Gerhard
RSC advances, ISSN 2046-2069, 2018, Volume 8, Issue 10, pp. 5243 - 5254
Alkaloids | Dimers | Metabolites | Toxicity | Pancreatic cancer | Cancer
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4. Full Text Xanthine Oxidase Inhibitory Activity of Vietnamese Medicinal Plants
by Nguyen, Mai Thanh Thi and Awale, Suresh and Tezuka, Yasuhiro and Tran, Quan Le and Watanabe, Hiroshi and Kadota, Shigetoshi and Institute of Natural Medicine and Toyama Medical and Pharmaceutical University
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2004, Volume 27, Issue 9, pp. 1414 - 1421
Vietnamese medicinal plant | Chrysanthemum sinense | xanthine oxidase inhibitory activity | gout | Xanthine oxidase inhibitory activity | Gout | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Plant Extracts - chemistry | Medicine, East Asian Traditional | Plants, Medicinal - chemistry | Vietnam | Plant Extracts - pharmacology | Chrysanthemum - chemistry | Xanthine Oxidase - antagonists & inhibitors | Index Medicus
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5. Full Text Two New Cytotoxic Phenylallylflavanones from Mexican Propolis
by Li, Feng and He, Yu-Min and Awale, Suresh and Kadota, Shigetoshi and Tezuka, Yasuhiro and aInstitute of Natural Medicine and University of Toyama and China Three Gorges University and bCollege of Medical Science
Chemical & pharmaceutical bulletin, ISSN 0009-2363, 2011, Volume 59, Issue 9, pp. 1194 - 1196
preferential cytotoxicity | phenylallylflavanone | PANC-1 cell | Mexican propolis | Preferential cytotoxicity | Phenylallylflavanone | Flavanones - isolation & purification | Flavanones - toxicity | Flavanones - chemistry | Magnetic Resonance Spectroscopy | Antineoplastic Agents - isolation & purification | Humans | Molecular Conformation | Cell Line, Tumor | Propolis - chemistry | Mexico | Antineoplastic Agents - chemistry | Antineoplastic Agents - toxicity | Index Medicus
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6. Full Text A New Ciprofloxacin-derivative Inhibits Proliferation and Suppresses the Migration Ability of HeLa Cells
by Fathy, Moustafa and Sun, Sijia and Zhao, Qing-Li and Abdel-Aziz, Mohamed and Abuo-Rahma, Gamal El-Din A and Awale, Suresh and Nikaido, Toshio
Anticancer research, ISSN 0250-7005, 09/2020, Volume 40, Issue 9, pp. 5025 - 5033
Life Sciences & Biomedicine | Oncology | Science & Technology | Cell proliferation | Flow cytometry | Wound healing | Bax protein | Colonies | Cytology | Cytotoxicity | Cell viability | Cervix | Drug development | Caspase-3 | Western blotting | Metastases | Proteins | Molecular modelling | Cell death | Morphology | Ciprofloxacin | Cell migration | Cervical cancer | Apoptosis | Index Medicus
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7. Full Text Ancistrolikokine E3, a 5,8′-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway
by Awale, Suresh and Dibwe, Dya Fita and Balachandran, Chandrasekar and Fayez, Shaimaa and Feineis, Doris and Lombe, Blaise Kimbadi and Bringmann, Gerhard
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 10/2018, Volume 81, Issue 10, pp. 2282 - 2291
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8. Full Text Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Ameliorated Unpredictable Chronic Mild Stress-Induced Cognitive Impairment in ICR Mice
by Maneenet, Juthamart and Daodee, Supawadee and Monthakantirat, Orawan and Boonyarat, Chantana and Khamphukdee, Charinya and Kwankhao, Pakakrong and Pitiporn, Supaporn and Awale, Suresh and Chulikhit, Yaowared and Kijjoa, Anake
Molecules (Basel, Switzerland), ISSN 1420-3049, 12/2019, Volume 24, Issue 24, p. 4587
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cognitive Dysfunction - drug therapy | Phytochemicals - chemistry | Plant Extracts - chemistry | Plants, Medicinal - chemistry | Plant Extracts - pharmacology | Brain - physiopathology | Chromatography, High Pressure Liquid | Cognition - drug effects | Cognitive Dysfunction - etiology | Thailand | Mice, Inbred ICR | Brain - drug effects | Brain - metabolism | Animals | Lipid Peroxidation - drug effects | Drug Compounding | Stress, Psychological | Mice | Molecular Structure | Oxidative Stress - drug effects | Adrenal Cortex Hormones - blood | Phytochemicals - pharmacology | Cell proliferation | Therapy | Oxidative stress | Seeds | Pathogenesis | Memory | Cognitive ability | Lipid peroxidation | Acetylcholinesterase | Neurogenesis | Antioxidants | Rhizomes | Vitamin E | Antidepressants | Dementia disorders | Anxiety | Drug dosages | Ultrasound | Medicinal plants | Aquatic plants | Embryos | Herbal medicine | Dentate gyrus | Flavonoids | Acids | Index Medicus
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9. Full Text Co‐cultured bone marrow mesenchymal stem cells repair thioacetamide‐induced hepatocyte damage
by Chen, Hung‐Chiuan and Awale, Suresh and Wu, Chean‐Ping and Lee, Hu‐Hui and Wu, Hsi‐Tien
Cell biology international, ISSN 1065-6995, 12/2020, Volume 44, Issue 12, pp. 2459 - 2472
thioacetamide | hepatocyte HepG2 | bone marrow mesenchymal stem cells | transwell co‐culture system | STAT3 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell culture | Collagen (type I) | Free radicals | Cell survival | Mesenchyme | Transcription | Stat3 protein | Stem cell transplantation | Superoxide dismutase | Inflammation | Gene expression | Immunosuppressive agents | Gelatinase B | Interleukin 6 | Antioxidants | Thioacetamide | Hepatocytes | Tumor necrosis factor | Stem cells | Fibrosis | Bone marrow | Extracellular matrix | Index Medicus
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10. Full Text A Triterpene Lactone from Callistemon citrinus Inhibits the PANC‐1 Human Pancreatic Cancer Cells Viability through Suppression of Unfolded Protein Response
by Tawila, Ahmed M and Sun, Sijia and Kim, Min Jo and Omar, Ashraf M and Dibwe, Dya Fita and Awale, Suresh
Chemistry & biodiversity, ISSN 1612-1872, 10/2020, Volume 17, Issue 10, pp. e2000495 - n/a
nutrient-deprived conditions | PANC-1 | proteins | triterpenes | anti-austerity | glucose-regulated proteins | cytotoxicity | TOR protein | Phosphorylation | Starvation | Cell survival | Toxicity | Tumor cells | Cytology | Cytotoxicity | AKT protein | Cell viability | Cell membranes | Rounding | Survival | Cell morphology | Cell adhesion & migration | Anticancer properties | Proteins | Protein folding | Cell death | Morphology | Pancreatic cancer | Nutrients | Cell migration | Tumors | Index Medicus
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11. Full Text Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative
by Devji, Tehsina and Reddy, Claire and Woo, Christina and Awale, Suresh and Kadota, Shigetoshi and Carrico-Moniz, Dora
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2011, Volume 21, Issue 19, pp. 5770 - 5773
Coumarins | Preferential cytotoxicity | Anticancer agents | Pancreatic cancer | PANC-1 | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Prenylation | Cell Survival | Antineoplastic Agents - chemical synthesis | Humans | Pancreatic Neoplasms - pathology | Pancreas - pathology | Coumarins - chemistry | Antineoplastic Agents - chemistry | Alkylation | Coumarins - pharmacology | Pancreatic Neoplasms - drug therapy | Coumarins - chemical synthesis | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Drug Screening Assays, Antitumor | Care and treatment | Cancer | Index Medicus
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12. Full Text Antimalarial Activity of Cassane- and Norcassane-Type Diterpenes from Caesalpinia crista and Their Structure-Activity Relationship
by Kalauni, Surya Kant and Awale, Suresh and Tezuka, Yasuhiro and Banskota, Arjun Hari and Linn, Thein Zaw and Asih, Puji Budi Setia and Syafruddin, Din and Kadota, Shigetoshi
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2006, Volume 29, Issue 5, pp. 1050 - 1052
norcassane-type diterpene | antimalarial activity | cassane-type diterpene | structure-activity relationship | Caesalpinia crista | Antimalarial activity | Norcassane-type diterpene | Cassane-type diterpene | Structure-activity relationship | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Diterpenes - pharmacology | Myanmar | Humans | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Antimalarials - pharmacology | Chloroquine - pharmacology | Animals | Caesalpinia - chemistry | Erythrocytes - parasitology | In Vitro Techniques | Diterpenes - chemistry | Indonesia | Index Medicus
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13. Full Text Chemical Constituents of Propolis from Vietnamese Trigona minor and Their Antiausterity Activity against the PANC‑1 Human Pancreatic Cancer Cell Line
by Nguyen, Hai X and Nguyen, Mai T. T and Nguyen, Nhan T and Awale, Suresh
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 08/2017, Volume 80, Issue 8, pp. 2345 - 2352
Triterpenes - pharmacology | Humans | Antineoplastic Agents, Phytogenic - chemistry | Pancreatic Neoplasms - drug therapy | Triterpenes - chemistry | Vietnam | Animals | Cell Line, Tumor | Nuclear Magnetic Resonance, Biomolecular | Propolis - chemistry | Triterpenes - isolation & purification | Molecular Structure | Drug Screening Assays, Antitumor | Index Medicus
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14. Full Text Ancistrosecolines A–F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells
by Fayez, Shaimaa and Bruhn, Torsten and Feineis, Doris and Assi, Laurent Aké and Awale, Suresh and Bringmann, Gerhard
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 04/2020, Volume 83, Issue 4, pp. 1139 - 1151
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15. Full Text Antiausterity Activity of Secondary Metabolites from the Roots of Ferula hezarlalehzarica against the PANC‑1 Human Pancreatic Cancer Cell Line
by Alilou, Mostafa and Dibwe, Dya Fita and Schwaiger, Stefan and Khodami, Mojtaba and Troppmair, Jakob and Awale, Suresh and Stuppner, Hermann
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 04/2020, Volume 83, Issue 4, pp. 1099 - 1106
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16. Full Text Cytotoxic Constituents of Propolis from Myanmar and Their Structure-Activity Relationship
by Li, Feng and Awale, Suresh and Tezuka, Yasuhiro and Kadota, Shigetoshi
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2009, Volume 32, Issue 12, pp. 2075 - 2078
propolis | flavanone | cycloartane-type triterpene | structure-activity relationship | cytotoxicity | Cytotoxicity | Flavanone | Propolis | Structure-activity relationship | Cycloartane-type triterpene | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Prenylation | Flavanones - isolation & purification | Myanmar | Triterpenes - pharmacology | Flavanones - therapeutic use | Flavanones - pharmacology | Humans | Triterpenes - therapeutic use | Structure-Activity Relationship | Apitherapy | Neoplasms - drug therapy | Animals | Cell Line, Tumor | Inhibitory Concentration 50 | Propolis - chemistry | Propolis - pharmacology | Triterpenes - isolation & purification | Female | Mice | Propolis - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - isolation & purification | Index Medicus
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