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NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3669 - 14
Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies of a... 
SURVIVAL | LIFE-SPAN | GWAS | CONFIRMS APOE | MULTIDISCIPLINARY SCIENCES | HEALTH | PREVALENCE | LD SCORE REGRESSION | LOCUS | HERITABILITY | AGE | Phenotypes | Apolipoprotein E | Genes | Association analysis | Genomes | Longevity | Gene expression | Survival | Age
Journal Article
by Evangelou, Evangelos and Warren, Helen R and Mosen-Ansorena, David and Mifsud, Borbala and Pazoki, Raha and Gao, He and Ntritsos, Georgios and Dimou, Niki and Cabrera, Claudia P and Karaman, Ibrahim and Ng, Fu Liang and Evangelou, Marina and Witkowska, Katarzyna and Tzanis, Evan and Hellwege, Jacklyn N and Giri, Ayush and Velez Edwards, Digna R and Sun, Yan V and Cho, Kelly and Gaziano, J.Michael and Wilson, Peter WF and Tsao, Philip S and Kovesdy, Csaba P and Esko, Tonu and Mägi, Reedik and Milani, Lili and Almgren, Peter and Boutin, Thibaud and Debette, Stéphanie and Ding, Jun and Giulianini, Franco and Holliday, Elizabeth G and Jackson, Anne U and Li-Gao, Ruifang and Lin, Wei-Yu and Luan, Jian'an and Mangino, Massimo and Oldmeadow, Christopher and Prins, Bram Peter and Qian, Yong and Sargurupremraj, Muralidharan and Shah, Nabi and Surendran, Praveen and Thériault, Sébastien and Verweij, Niek and Willems, Sara M and Zhao, Jing-Hua and Amouyel, Philippe and Connell, John and de Mutsert, Renée and Doney, Alex SF and Farrall, Martin and Menni, Cristina and Morris, Andrew D and Noordam, Raymond and Paré, Guillaume and Poulter, Neil R and Shields, Denis C and Stanton, Alice and Thom, Simon and Abecasis, Gonçalo and Amin, Najaf and Arking, Dan E and Ayers, Kristin L and Barbieri, Caterina M and Batini, Chiara and Bis, Joshua C and Blake, Tineka and Bochud, Murielle and Boehnke, Michael and Boerwinkle, Eric and Boomsma, Dorret I and Bottinger, Erwin P and Braund, Peter S and Brumat, Marco and Campbell, Archie and Campbell, Harry and Chakravarti, Aravinda and Chambers, John C and Chauhan, Ganesh and Ciullo, Marina and Cocca, Massimiliano and Collins, Francis and Cordell, Heather J and Davies, Gail and de Borst, Martin H and de Geus, Eco J and Deary, Ian J and Deelen, Joris and Del Greco, M Fabiola and Demirkale, Cumhur Yusuf and Dörr, Marcus and Ehret, Georg B and Elosua, Roberto and Enroth, Stefan and Erzurumluoglu, A Mesut and Ferreira, Teresa and Frånberg, Mattias and Franco, Oscar H and Gandin, Ilaria and ...
Nature genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1412 - 1425
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood... 
Journal Article
BMC Genomics, ISSN 1471-2164, 06/2016, Volume 17, Issue Suppl 2
Alzheimer's disease (AD) represents the most common form of dementia in elder populations with approximately 30 million cases worldwide. Genome wide genotyping... 
Analysis | Genetic aspects | Diagnosis | Research | Homozygosity | Alzheimer's disease | Risk factors | Dementia
Journal Article
by Evangelou, Evangelos and Warren, Helen R and Mosen-Ansorena, David and Mifsud, Borbala and Pazoki, Raha and Gao, He and Ntritsos, Georgios and Dimou, Niki and Cabrera, Claudia P and Karaman, Ibrahim and Ng, Fu Liang and Evangelou, Marina and Witkowska, Katarzyna and Tzanis, Evan and Hellwege, Jacklyn N and Giri, Ayush and Velez Edwards, Digna R and Sun, Yan V and Cho, Kelly and Gaziano, J Michael and Wilson, Peter W F and Tsao, Philip S and Kovesdy, Csaba P and Esko, Tonu and Mägi, Reedik and Milani, Lili and Almgren, Peter and Boutin, Thibaud and Debette, Stéphanie and Ding, Jun and Giulianini, Franco and Holliday, Elizabeth G and Jackson, Anne U and Li-Gao, Ruifang and Lin, Wei-Yu and Luan, Jian'an and Mangino, Massimo and Oldmeadow, Christopher and Prins, Bram Peter and Qian, Yong and Sargurupremraj, Muralidharan and Shah, Nabi and Surendran, Praveen and Thériault, Sébastien and Verweij, Niek and Willems, Sara M and Zhao, Jing-Hua and Amouyel, Philippe and Connell, John and de Mutsert, Renée and Doney, Alex S F and Farrall, Martin and Menni, Cristina and Morris, Andrew D and Noordam, Raymond and Paré, Guillaume and Poulter, Neil R and Shields, Denis C and Stanton, Alice and Thom, Simon and Abecasis, Gonçalo and Amin, Najaf and Arking, Dan E and Ayers, Kristin L and Barbieri, Caterina M and Batini, Chiara and Bis, Joshua C and Blake, Tineka and Bochud, Murielle and Boehnke, Michael and Boerwinkle, Eric and Boomsma, Dorret I and Bottinger, Erwin P and Braund, Peter S and Brumat, Marco and Campbell, Archie and Campbell, Harry and Chakravarti, Aravinda and Chambers, John C and Chauhan, Ganesh and Ciullo, Marina and Cocca, Massimiliano and Collins, Francis and Cordell, Heather J and Davies, Gail and de Borst, Martin H and de Geus, Eco J and Deary, Ian J and Deelen, Joris and Del Greco M, Fabiola and Demirkale, Cumhur Yusuf and Dörr, Marcus and Ehret, Georg B and Elosua, Roberto and Enroth, Stefan and Erzurumluoglu, A Mesut and Ferreira, Teresa and Frånberg, Mattias and Franco, Oscar H and Gandin, Ilaria and ... and Science for Life Laboratory, SciLifeLab and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 2018, Volume 50, Issue 10, p. 1412
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood... 
Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Wain, Louise V and Vaez, Ahmad and Jansen, Rick and Joehanes, Roby and van der Most, Peter J and Erzurumluoglu, A Mesut and O'Reilly, Paul F and Cabrera, Claudia P and Warren, Helen R and Rose, Lynda M and Verwoert, Germaine C and Hottenga, Jouke-Jan and Strawbridge, Rona J and Esko, Tonu and Arking, Dan E and Hwang, Shih-Jen and Guo, Xiuqing and Kutalik, Zoltan and Trompet, Stella and Shrine, Nick and Teumer, Alexander and Ried, Janina S and Bis, Joshua C and Smith, Albert V and Amin, Najaf and Nolte, Ilja M and Lyytikäinen, Leo-Pekka and Mahajan, Anubha and Wareham, Nicholas J and Hofer, Edith and Joshi, Peter K and Kristiansson, Kati and Traglia, Michela and Havulinna, Aki S and Goel, Anuj and Nalls, Mike A and Sõber, Siim and Vuckovic, gana and Luan, Jian'an and Del Greco M, Fabiola and Ayers, Kristin L and Marrugat, Jaume and Ruggiero, Daniela and Lopez, Lorna M and Niiranen, Teemu and Enroth, Stefan and Jackson, Anne U and Nelson, Christopher P and Huffman, Jennifer E and Zhang, Weihua and Marten, Jonathan and Gandin, Ilaria and Harris, Sarah E and Zemunik, Tatijana and Lu, Yingchang and Evangelou, Evangelos and Shah, Nabi and de Borst, Martin H and Mangino, Massimo and Prins, Bram P and Campbell, Archie and Li-Gao, Ruifang and Chauhan, Ganesh and Oldmeadow, Christopher and Abecasis, Gonçalo R and Abedi, Maryam and Barbieri, Caterina M and Barnes, Michael R and Batini, Chiara and Beilby, John and Blake, Tineka and Boehnke, Michael and Bottinger, Erwin P and Braund, Peter S and Brown, Morris and Brumat, Marco and Campbell, Harry and Chambers, John C and Cocca, Massimiliano and Collins, Francis S and Connell, John and Cordell, Heather J and Damman, Jeffrey J and Davies, Gail and de Geus, Eco J and de Mutsert, Renée and Deelen, Joris and Demirkale, Yusuf and Doney, Alex S F and Dörr, Marcus and Farrall, Martin and Ferreira, Teresa and Frånberg, Mattias and Gao, He and Gieaitis, Vilmantas and Gieger, Christian and Giulianini, Franco and Gow, Alan J and Hamsten, Anders and Harris, Tamara B and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinsk genetik och genomik and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Hypertension, ISSN 0194-911X, 07/2017, Volume 70, Issue 3, p. E4
Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood... 
Kardiologi | Clinical Medicine | blood pressure | Cardiac and Cardiovascular Systems | GWAS | Medical and Health Sciences | Medicin och hälsovetenskap | complex traits | cardiovascular risk | Klinisk medicin | hypertension | eSNP
Journal Article
by Warren, Helen R and Evangelou, Evangelos and Cabrera, Claudia P and Gao, He and Ren, Meixia and Mifsud, Borbala and Ntalla, Ioanna and Surenan, Praveen and Liu, Chunyu and Cook, James P and Kraja, Aldi T and nos, Fotios and Loh, Marie and Verweij, Niek and Marten, Jonathan and Karaman, Ibrahim and Lepe, Marcelo P. Segura and O'Reilly, Paul F and Knight, Joanne and Snieder, Harold and Kato, Norihiro and He, Jiang and Tai, E. Shyong and Said, M. Abdullah and Porteous, David and Alver, Maris and Poulter, Neil and Farrall, Martin and Gansevoort, Ron T and Padmanabhan, Sandosh and Magi, Reedik and Stanton, Alice and Connell, John and Bakker, Stephan J. L and Metspalu, Anes and Shields, Denis C and Thom, Simon and Brown, Morris and Sever, Peter and Esko, Tonu and Hayward, Caroline and van der Harst, Pim and Saleheen, Danish and Chowdhury, Rajiv and Chambers, John C and Chasman, Daniel I and Chakravarti, Aravinda and Newton-Cheh, Christopher and Lindgren, Cecilia M and Levy, Daniel and Kooner, Jaspal S and Keavney, Bernard and Tomaszewski, Maciej and Samani, Nilesh J and Howson, Joanna M. M and Tobin, Martin D and Munroe, Patricia B and Ehret, Georg B and Wain, Louise V and Barnes, Michael R and Tzoulaki, Joanna and Caulfield, Mark J and Elliott, Paul and Vaez, Ahmad and Jansen, Rick and Joehanes, Roby and van der Most, Peter J and Erzurumluoglu, A. Mesut and O'Reilly, Paul and Rose, Lynda M and Verwoert, Germaine C and Hottenga, Jouke-Jan and Strawbridge, Rona J and Arking, Dan E and Hwang, Shih-Jen and Guo, Xiuqing and Kutalik, Zoltan and Trompet, Stella and Shrine, Nick and Teumer, Alexander and Ried, Janina S and Bis, Joshua C and Smith, Albert V and Amin, Najaf and Nolte, Ilja M and Lyytikainen, Leo-Pekka and Mahajan, Anubha and Wareham, Nicholas J and Hofer, Edith and Joshi, Peter K and Kristiansson, Kati and Traglia, Michela and Havulinna, Aki S and Goel, Anuj and Nalls, Mike A and Sober, Siim and Vuckovic, gana and Luan, Jian'an and del Greco, Fabiola M and Ayers, Kristin L and ... and CHARGE BP Exome Consortium and UK Biobank CardioMetab Consortium and GoT2D Genes Consortium and Understanding Soc Sci Grp and Lifelines Cohort Study and Int Consortium Blood Pressure ICBP and BIOS Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-GENES Consortium and iGEN-BP Consortium and International Consortium of Blood Pressure (ICBP) 1000G Analyses and Understanding Society Scientific group and CHD Exome+ Consortium and Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium and International Genomics of Blood Pressure (iGEN-BP) Consortium and UK Biobank CardioMetabolic Consortium BP working group and GoT2DGenes Consortium and The CHD Exome+ Consortium and The International Consortium of Blood Pressure (ICBP) 1000G Analyses and The International Genomics of Blood Pressure (iGEN-BP) Consortium and The UK Biobank CardioMetabolic Consortium BP working group and The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium and The GoT2DGenes Consortium and The ExomeBP Consortium and The T2D-GENES Consortium and Stockholms universitet and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 3, pp. 403 - 415
Journal Article
by Deelen, Joris and Beekman, Marian and Uh, Hae-Won and Broer, Linda and Ayers, Kristin and Tan, Qihua and Kamatani, Yoichiro and Bennet, Anna Michaela and Tamm, Riin and Trompet, Stella and Guobjartsson, Daníel and Flachsbart, Friederike and Rose, Giuseppina and Viktorin, Alexander and Fischer, Krista and Nygaard, Marianne and Cordell, Heather and Crocco, Paolina and Akker, Erik and Böhringer, Stefan and Helmer, Quinta and Nelson, Christopher P and Saunders, Gary and Alver, Maris and Andersen-Ranberg, Karen and Breen, Gerome and Breggen, Ruud and Caliebe, Amke and Capri, Yline and Cevenini, Elisa and Collerton, Joanna and Dato, Serena and Davies, Karen and Ford, Ian and Gampe, Jutta and Garagnani, Paolo and Geus, Eco and Harrow, Jennifer and Heemst, Diana and Heijmans, Bastiaan and Heinsen, Femke-Anouska and Hottenga, Jouke Jan and Hofman, Albert and Jeune, Bernard and Jonsson, Palmi and Lathrop, Mark and Lechner, Doris and Martin-Ruiz, Carmen and Mcnerlan, Susan and Mihailov, Evelin and Montesanto, Alberto and Mooijaart, Simon and Murphy, Anne and Nohr, Christian and Paternoster, Lavinia and Postmus, Douwe and Rivadeneira Ramirez, Fernando and Ross, Owen and Salvioli, Stefano and Sattar, Naveed and Schreiber, Stefan and Stefansson, Hreinn and Stott, David. J and Tiemeier, Henning and Uitterlinden, Ané and Westendorp, Rudi and Willemsen, Gonneke and Samani, Nilesh and Galan, Pilar and Sorensen, H.G and Boomsma, Dorret and Jukema, Jan Wouter and Rea, Dan and Passarino, Giuseppe and Craen, Anton and Christensen, Kaare and Nebel, Almut and Zwart, John-Anker and Metspalu, Anes and Magnusson, Patrik and Blanché, Hélène and Christiansen, Lene and Kirkwood, John and Duijn, Cornelia and Franceschi, Claudio and Houwing-Duistermaat, Jeanine and Slagboom, Eline
Human Molecular Genetics, ISSN 0964-6906, 01/2014, Volume 23, Issue 16, pp. 4420 - 4432
Journal Article
by Evangelou, Evangelos and Warren, Helen R and Mosen-Ansorena, David and Mifsud, Borbala and Pazoki, Raha and Gao, He and Ntritsos, Georgios and Dimou, Niki and Cabrera, Claudia P and Karaman, Ibrahim and Ng, Fu Liang and Evangelou, Marina and Witkowska, Katarzyna and Tzanis, Evan and Hellwege, Jacklyn N and Giri, Ayush and Velez Edwards, Digna R and Sun, Yan V and Cho, Kelly and Gaziano, J. Michael and Wilson, Peter W. F and Tsao, Philip S and Kovesdy, Csaba P and Esko, Tonu and Mägi, Reedik and Milani, Lili and Almgren, Peter and Boutin, Thibaud and Debette, Stéphanie and Ding, Jun and Giulianini, Franco and Holliday, Elizabeth G and Jackson, Anne U and Li-Gao, Ruifang and Lin, Wei-Yu and Luan, Jian’an and Mangino, Massimo and Oldmeadow, Christopher and Prins, Bram Peter and Qian, Yong and Sargurupremraj, Muralidharan and Shah, Nabi and Surendran, Praveen and Thériault, Sébastien and Verweij, Niek and Willems, Sara M and Zhao, Jing-Hua and Amouyel, Philippe and Connell, John and de Mutsert, Renée and Doney, Alex S. F and Farrall, Martin and Menni, Cristina and Morris, Andrew D and Noordam, Raymond and Paré, Guillaume and Poulter, Neil R and Shields, Denis C and Stanton, Alice and Thom, Simon and Abecasis, Gonçalo and Amin, Najaf and Arking, Dan E and Ayers, Kristin L and Barbieri, Caterina M and Batini, Chiara and Bis, Joshua C and Blake, Tineka and Bochud, Murielle and Boehnke, Michael and Boerwinkle, Eric and Boomsma, Dorret I and Bottinger, Erwin P and Braund, Peter S and Brumat, Marco and Campbell, Archie and Campbell, Harry and Chakravarti, Aravinda and Chambers, John C and Chauhan, Ganesh and Ciullo, Marina and Cocca, Massimiliano and Collins, Francis and Cordell, Heather J and Davies, Gail and Borst, Martin H. de and Geus, Eco J. de and Deary, Ian J and Deelen, Joris and Del Greco M, Fabiola and Demirkale, Cumhur Yusuf and Dörr, Marcus and Ehret, Georg B and Elosua, Roberto and Enroth, Stefan and Erzurumluoglu, A. Mesut and Ferreira, Teresa and Frånberg, Mattias and Franco, Oscar H and Gandin, Ilaria and ... and Million Vet Program and Million Veteran Program and the Million Veteran Program and Stockholms universitet and Matematiska institutionen and Naturvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1412 - 1425
Journal Article
Aging Cell, ISSN 1474-9718, 04/2013, Volume 12, Issue 2, pp. 184 - 193
Journal Article